Reaction

Antipsychotic Drug Level Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,779 reports · 71 co-occurring drugs

As of the last recalculation, Antipsychotic Drug Level Increased appears in 2,779 FAERS reports alongside 71 co-occurring drug terms. The strongest observed disproportionality signal is CLOZAPINE (PRR 228.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Clozapine	1,615	228.6	231.6
Lithium Carbonate	239	115.2	116.9
Lithium	241	78.3	79.0
Lithium Bromatum	241	78.3	79.0
Valproate Sodium	123	46.6	46.9
Aripiprazole Oral	175	33.8	33.9
Aripiprazole Orally Disintegrating	175	33.8	33.9
Haloperidol	92	29.3	29.4
Haloperidol Lactate	93	29.1	29.2
Valproic Acid	96	23.6	23.7
Olanzapine	295	22.9	22.9
Atropine	23	21.0	21.0
Atropine Sulfate	23	16.1	16.1
Fluoxetine	132	15.5	15.5
Aripiprazole	229	15.2	15.2
Divalproex Sodium	89	14.8	14.8
Nicotine Polacrilex Mini	26	13.1	13.1
Nicotine Polarilex	26	13.1	13.1
Ziprasidone	28	12.0	12.0
Sennosides 8.6 Mg Tablets	33	11.9	11.9
Quetiapine	278	11.9	11.9
Senna	33	11.9	11.9
Paliperidone	36	11.7	11.7
Lactulose	58	11.6	11.6
Lamotirigine	106	11.5	11.5
Lamotrigine Extended-Release	106	11.5	11.5
Lamotrigine Chewable Dispersible	106	11.5	11.5
Risperidone	181	10.8	10.9
Senna Leaf	33	10.8	10.8
Sertraline	158	10.6	10.6
Olanzapine Pamoate	57	10.6	10.6
Fluoxetine Hydrochloride	169	10.5	10.5
Diazepam Oral Solution (Concentrate)	117	10.2	10.2
Diazepam Oral	117	10.2	10.2
Quetiapine Fumarate	39	10.0	10.0
Oxazepam	28	9.8	9.9
Paroxetine Hydrochloride Hemihydrate	41	9.3	9.4
Paroxetine	41	9.2	9.2
Sennosides	35	8.9	8.9
Diazepam	132	8.5	8.5
Lamotrigine	140	8.3	8.3
Venlafaxine	76	8.1	8.2
Cariprazine	10	8.1	8.1
Instalax Polyethylene Glycol 3350	13	7.9	7.9
Thiamine Hydrochloride	13	7.9	7.9
Polyethylene Glycol 400	13	7.7	7.7
Gemfibrozil	13	6.4	6.4
Lurasidone Hydrochloride	17	6.1	6.1
Mirtazapine	71	5.9	5.9
Derma Foam Excel Hand Sanitizer	6	5.6	5.6
Paliperidone Palmitate	24	5.6	5.6
Ethanol	6	5.6	5.6
Escitslopram	41	5.3	5.3
Nicotine Polacrilex	27	5.3	5.3
Citalopram Hydrobromide	74	5.3	5.3
Propranolol Hydrochloride	50	5.3	5.3
Asenapine Maleate	6	5.2	5.2
Nicotine	27	5.0	5.0
Umeclidinium	6	5.0	5.0
Dolutegravir Sodium	6	5.0	5.0
Brexpiprazole	10	4.5	4.5
Febuxostat Tablets 40 Mg	6	4.4	4.4
Febuxostat Tablets 80 Mg	6	4.4	4.4
Ethyl Alcohol	14	3.9	3.9
Alcohol	19	3.7	3.7
Amphetamine	4	3.6	3.6
Isopropyl Alcohol	13	2.9	2.9
Oseltamivir	3	2.8	2.8
Methoxy Polyethylene Glycol-Epoetin Beta	4	2.7	2.7
Sevelamer Carbonate	3	2.0	2.0
Valbenazine	6	1.8	1.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.