Reaction
Application Site Swelling reporting signals
As of the last recalculation, Application Site Swelling appears in 4,930 FAERS reports alongside 38 co-occurring drug terms. The strongest observed disproportionality signal is NICOTINE (PRR 79.2).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Nicotine | 659 | 79.2 | 80.5 |
| Glycerin, Lidocaine | 208 | 65.4 | 66.4 |
| Docosanol | 208 | 62.5 | 63.4 |
| Crisaborole | 78 | 34.9 | 35.1 |
| Methylphenidate | 168 | 25.3 | 25.5 |
| Rotigotine | 52 | 15.3 | 15.4 |
| Nicotine Polacrilex | 128 | 14.5 | 14.5 |
| Tretinoin | 26 | 13.6 | 13.6 |
| Miconazole Nitrate | 23 | 11.2 | 11.2 |
| Estradiol | 179 | 9.0 | 9.1 |
| Nicotine Polacrilex Mini | 30 | 8.5 | 8.5 |
| Nicotine Polarilex | 30 | 8.5 | 8.5 |
| Buprenorphine | 158 | 7.4 | 7.4 |
| Rivastigmine | 29 | 6.5 | 6.5 |
| Oxybutynin | 41 | 6.0 | 6.0 |
| Progesterone | 28 | 5.2 | 5.2 |
| Mupirocin | 16 | 5.0 | 5.0 |
| Mupirocin Calcium | 16 | 4.9 | 4.9 |
| Minoxidil Foam 5% (Womens) | 37 | 4.8 | 4.8 |
| Minoxidil | 49 | 4.6 | 4.6 |
| Ketoconazole | 16 | 3.9 | 3.9 |
| Ketoconazole Foam | 13 | 3.7 | 3.7 |
| Ketoconazole Cream, 2% | 13 | 3.7 | 3.7 |
| Triamcinolone Acetonide Ointment Usp, 0.05% | 19 | 3.4 | 3.4 |
| Clonidine | 40 | 3.3 | 3.3 |
| Estradiol Gel 0.1% | 33 | 3.1 | 3.1 |
| Estradiol Transdermal | 33 | 3.1 | 3.1 |
| Travoprost | 6 | 2.9 | 2.9 |
| Salicylic Acid | 33 | 2.6 | 2.6 |
| Pegfilgrastim | 61 | 2.6 | 2.6 |
| Diclofenac Sodium | 92 | 2.6 | 2.6 |
| Triamcinolone Acetonide | 19 | 2.6 | 2.6 |
| Minocycline | 7 | 2.5 | 2.5 |
| Brimonidine Tartrate | 8 | 1.9 | 1.9 |
| Timolol | 5 | 1.7 | 1.7 |
| Bimatoprost | 10 | 1.5 | 1.5 |
| Evolocumab | 50 | 1.3 | 1.3 |
| Adapalene | 12 | 0.3 | 0.3 |