Reaction

Hypertensive Heart Disease reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,858 reports · 61 co-occurring drugs

As of the last recalculation, Hypertensive Heart Disease appears in 1,858 FAERS reports alongside 61 co-occurring drug terms. The strongest observed disproportionality signal is AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (PRR 22.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Amlodipine Besylate And Benazepril Hydrochloride	18	22.0	22.1
Sevelamer Carbonate	17	16.7	16.7
Torsemide	48	16.6	16.7
Cefepime	20	15.8	15.8
Quinine	12	15.8	15.8
Carisoprodol	26	15.5	15.5
Cefepime Hydrochloride	21	14.8	14.8
Epoetin Alfa	14	13.3	13.3
Methoxy Polyethylene Glycol-Epoetin Beta	13	13.3	13.3
Felodipine Extended-Release Tablets	13	12.9	12.9
Felodipine	13	12.9	12.9
Tolterodine Tartrate	10	12.5	12.6
Diltiazem Hydrochloride	38	12.5	12.6
Valsartan And Hydrochlorothiazide	14	11.6	11.6
Enalapril Maleate	25	11.4	11.4
Cyclobenzaprine Hydrochloride	9	11.3	11.3
Isosorbide Dinitrate	19	11.0	11.0
Glyburide	23	10.8	10.8
Temazepam	35	10.6	10.6
Cimetidine	9	10.5	10.5
Digoxin	65	10.5	10.5
Doxazosin Mesylate	33	10.4	10.4
Meclizine Hcl 12.5Mg	12	9.9	9.9
Meclizine Hcl 25Mg	12	9.9	9.9
Meclizine Hcl 12.5 Mg	12	9.9	9.9
Meclizine Hcl 25 Mg	12	9.9	9.9
Candesartan	31	9.9	9.9
Losartan Potassium And Hydrochlorothiazide	10	9.7	9.7
Paricalcitol	12	9.6	9.6
Valsartan Oral	44	9.3	9.3
Valsartan	82	9.1	9.1
Metolazone	9	9.0	9.0
Meclizine	13	9.0	9.0
Nitroglycerin	42	9.0	9.0
Doxazosin	22	8.9	8.9
Clonidine	38	8.5	8.5
Enalapril	41	8.4	8.4
Ziprasidone	13	8.3	8.3
Nicotine Polacrilex Mini	11	8.3	8.3
Nicotine Polarilex	11	8.3	8.3
Labetalol	9	7.6	7.6
Carvedilol	85	7.3	7.3
Dapagliflozin	20	7.2	7.2
Glipizide	37	6.9	6.9
Ceftriaxone	20	6.9	6.9
Ceftriaxone Sodium	22	6.5	6.5
Ethyl Alcohol	14	5.8	5.8
Pioglitazone	20	5.2	5.2
Isopropyl Alcohol	15	5.0	5.0
Alcohol	17	4.9	4.9
Tafamidis	5	4.8	4.8
Hydrocodone Bitartrate And Acetaminophen	23	4.6	4.6
Sacubitril And Valsartan	46	4.5	4.5
Loratadine And Pseudoephedrine Sulfate	3	4.2	4.2
Derma Foam Excel Hand Sanitizer	3	4.2	4.2
Ethanol	3	4.2	4.2
Ranibizumab	8	3.4	3.4
Conjugated Estrogens And Medroxyprogesterone Acetate	7	3.3	3.3
Budesonide, Glycopyrrolate, And Formoterol Fumarate	3	3.2	3.2
Hydrocodone Bitartrate	12	3.1	3.1
Cinacalcet Hydrochloride	7	1.7	1.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.