OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Hypospadias reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,037 reports · 48 co-occurring drugs

As of the last recalculation, Hypospadias appears in 2,037 FAERS reports alongside 48 co-occurring drug terms. The strongest observed disproportionality signal is ZIDOVUDINE (PRR 56.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Zidovudine7156.256.5
Valproate Sodium9348.148.3
Valproic Acid10535.836.0
Progesterone6530.030.1
Lamotirigine18629.129.2
Lamotrigine Extended-Release18629.129.2
Lamotrigine Chewable Dispersible18629.129.2
Clobazam5021.421.5
Lamotrigine21918.918.9
Carbamazepine11618.718.7
Topiramate15117.817.8
Lamivudine4816.216.3
Misoprostol1515.815.9
Lopinavir And Ritonavir2015.215.2
Lamivudine Oral3715.215.2
Levetiracetam In Sodium Chloride10414.414.4
Levetiracetam Oral10414.414.4
Levetiracetam Injection10414.414.4
Labetalol1813.913.9
Ritonavir 100 Mg1913.113.1
Vigabatrin1812.712.7
Zonisamide1611.111.1
Ritonavir3111.011.0
Levetiracetam13010.610.6
Phenytoin2110.410.4
Aripiprazole Oral4110.310.3
Aripiprazole Orally Disintegrating4110.310.3
Tenofovir Disoproxil Fumarate Tablets89.59.5
Citalopram Hydrobromide919.09.0
Ampicillin78.78.7
Ampicillin Sodium78.78.7
Drs. Clotrimazole98.08.0
Family Wellness Clotrimazole98.08.0
Clotrimazole Topical98.08.0
Paroxetine Hydrochloride687.97.9
Atazanavir117.97.9
Lithium197.87.8
Lithium Bromatum197.87.8
Dutasteride67.67.6
Clotrimazole97.57.5
Darunavir117.57.5
Efavirenz87.47.4
Rizatriptan Benzoate77.17.1
Cetirizine Hcl66.76.7
Divalproex Sodium306.76.7
Phenobarbital96.46.4
Emtricitabine And Tenofovir Disoproxil Fumarate204.54.5
Tenofovir Disoproxil Fumarate123.73.7

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.