Reaction

Drug Effect Delayed reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,538 reports · 56 co-occurring drugs

As of the last recalculation, Drug Effect Delayed appears in 4,538 FAERS reports alongside 56 co-occurring drug terms. The strongest observed disproportionality signal is LORATADINE AND PSEUDOEPHEDRINE SULFATE (PRR 48.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Loratadine And Pseudoephedrine Sulfate	82	48.1	48.6
Methylphenidate	114	18.5	18.6
Ibuprofen Sodium	146	16.1	16.2
Ibuprofen Tablets, Coated	143	15.9	15.9
Polyethylene Glycol 3350	290	14.8	14.8
Rasagiline Mesylate	33	13.7	13.7
Suvorexant	36	12.8	12.9
Carbidopa And Levodopa	124	12.3	12.3
Oxybutynin	76	12.1	12.1
Loratadine Tablet	121	10.6	10.6
Glycerin, Lidocaine	30	9.9	9.9
Docosanol	30	9.4	9.5
Ibuprofen And Diphenhydramine Citrate	41	8.1	8.2
Loperamide Hydrochloride Oral	18	8.1	8.1
Loratadine	172	7.6	7.6
Naproxen Sodium Tablet	80	7.0	7.0
Loperamide Hcl	19	6.8	6.8
Sildenafil Citrate	156	5.8	5.8
Lisdexamfetamine Dimesylate	39	5.5	5.5
Fexofenadine Hydrochloride	25	5.3	5.3
Magnesium Hydroxide	14	4.8	4.8
Acetaminophen, Aspirin (Nsaid) And Caffeine	17	4.6	4.6
Amantadine	15	4.5	4.5
Etanercept	460	3.8	3.8
Acetaminophen, Aspirin, And Caffeine	17	3.7	3.7
Instalax Polyethylene Glycol 3350	10	3.7	3.7
Romiplostim	12	3.7	3.7
Polyethylene Glycol 400	10	3.6	3.6
Ibuprofen	199	3.5	3.5
Thyroid, Porcine	8	3.4	3.5
Armodafinil	15	3.3	3.3
Naproxen Sodium	98	3.2	3.2
Rizatriptan Benzoate	7	3.2	3.2
Sumatriptan	25	3.0	3.0
Insulin Human	26	3.0	3.0
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	27	3.0	3.0
Ropinirole	10	3.0	3.0
Guanfacine	5	2.9	2.9
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	22	2.9	2.9
Rocuronium Bromide	7	2.7	2.7
Methylphenidate Hydrochloride	34	2.6	2.6
Linaclotide	15	2.6	2.6
Conjugated Estrogens	30	2.4	2.4
Lifitegrast	8	2.2	2.2
Fesoterodine Fumarate	5	2.1	2.1
Secukinumab	70	2.0	2.0
Erenumab-Aooe	24	2.0	2.0
Tofacitinib	74	1.9	1.9
Mometasone Furoate And Formoterol Fumarate Dihydrate	6	1.8	1.8
Sevoflurane	3	1.7	1.7
Crisaborole	3	1.4	1.4
Minoxidil	14	1.4	1.4
Droxidopa	6	1.3	1.3
Varenicline Tartrate	22	1.3	1.3
Buprenorphine	22	1.1	1.1
Dalfampridine	17	1.1	1.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.