Reaction

Anxiety Disorder reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,316 reports · 167 co-occurring drugs

As of the last recalculation, Anxiety Disorder appears in 3,316 FAERS reports alongside 167 co-occurring drug terms. The strongest observed disproportionality signal is ASENAPINE MALEATE (PRR 28.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Asenapine Maleate	39	28.6	28.7
Valsartan Oral	120	14.3	14.4
Doxepin	20	12.5	12.5
Doxepin Hydrochloride	24	12.0	12.0
Etonogestrel And Ethinyl Estradiol	36	10.3	10.3
Duloxetine	108	10.0	10.0
Diazepam Oral Solution (Concentrate)	136	10.0	10.0
Diazepam Oral	136	10.0	10.0
Memantine	21	9.7	9.7
Memantine Hydrochloride	21	9.7	9.7
Alendronate Sodium	147	9.5	9.5
Diazepam	174	9.4	9.4
Carisoprodol	27	8.9	9.0
Hyoscyamine Sulfate	13	8.9	8.9
Mirtazapine	125	8.9	8.9
Tizanidine Hydrochloride	25	8.7	8.8
Quetiapine Fumarate	40	8.6	8.6
Valsartan	138	8.6	8.6
Torsemide	43	8.2	8.3
Senna Leaf	29	8.0	8.0
Cimetidine	12	7.8	7.9
Hydrocodone Bitartrate And Acetaminophen	68	7.7	7.7
Valproate Sodium	25	7.6	7.7
Escitslopram	68	7.5	7.5
Isosorbide Mononitrate	24	7.3	7.3
Isosorbide Dinitrate	22	7.1	7.1
Ziprasidone Mesylate	16	7.1	7.1
Brivaracetam	10	7.0	7.0
Trazodone Hydrochloride	17	6.9	6.9
Amitriptyline Hydrochloride	19	6.8	6.8
Escitalopram Oxalate	76	6.7	6.7
Cefuroxime	12	6.6	6.6
Paroxetine Hydrochloride Hemihydrate	34	6.5	6.5
Fluoxetine Hydrochloride	126	6.4	6.4
Methocarbamol Tablets	17	6.4	6.4
Alprazolam	199	6.4	6.4
Paroxetine	34	6.3	6.3
Cetirizine Hydrochloride Allergy	30	6.3	6.3
Cetirizine Hydrochloride Tablets	30	6.3	6.3
Quetiapine	182	6.2	6.2
Lamotirigine	69	6.2	6.2
Lamotrigine Extended-Release	69	6.2	6.2
Lamotrigine Chewable Dispersible	69	6.2	6.2
Zolpidem Tartrate	127	6.1	6.1
Candesartan Cilexetil	25	6.0	6.0
Duloxetine Hydrochloride	169	5.9	5.9
Methocarbamol	21	5.8	5.8
Escitalopram	126	5.8	5.8
Paroxetine Hydrochloride	82	5.8	5.8
Ziprasidone	16	5.7	5.7
Hydroxyzine	43	5.7	5.7
Temazepam	34	5.7	5.7
Ciprofolxacin	64	5.7	5.7
Ciprofloxacin Tablets	64	5.7	5.7
Senna	19	5.7	5.7
Ciprofloxacin Hydrochloride	86	5.7	5.7
Guanfacine	7	5.6	5.6
Nitroglycerin	47	5.6	5.6
Metoclopramide Hydrochloride	67	5.5	5.5
Lisinopril And Hydrochlorothiazide	9	5.5	5.5
Cephalexin	19	5.5	5.5
Lorazepam	152	5.5	5.5
Vilazodone Hydrochloride	8	5.5	5.5
Loratadine Tablet	46	5.4	5.4
Sennosides 8.6 Mg Tablets	18	5.4	5.4
Bisacodyl	12	5.4	5.4
Bisacodyl Suppositories	11	5.4	5.4
Biscodyl	11	5.3	5.3
Lamotrigine	108	5.3	5.3
Clonazepam	130	5.3	5.3
Metoclopramide	45	5.2	5.2
Fluticasone Furoate	10	5.2	5.2
Rosuvastatin Calcium	23	5.2	5.2
Mometasone	15	5.2	5.2
Buspirone Hydrochloride	9	5.1	5.1
Ciprofloxacin	73	5.1	5.1
Montelukast Sodium	96	5.1	5.1
Liothyronine Sodium	7	5.1	5.1
Gemfibrozil	12	5.0	5.0
Rizatriptan Benzoate	8	4.9	4.9
Citalopram	105	4.9	4.9
Sertraline Hydrochloride	91	4.9	4.9
Doxyclycline Hyclate	13	4.8	4.8
Clarithromycin	26	4.8	4.8
Meperidine Hydrochloride	7	4.8	4.8
Finasteride	45	4.7	4.7
Venlafaxine Hydrochloride	97	4.7	4.7
Venlafaxine	53	4.7	4.7
Olanzapine Pamoate	30	4.6	4.6
Ibuprofen And Diphenhydramine Citrate	17	4.6	4.6
Tramadol Hydrochloride	27	4.5	4.5
Fluoxetine	47	4.5	4.5
Pregabalin	185	4.5	4.5
Empagliflozin	47	4.4	4.4
Raloxifene Hydrochloride	10	4.3	4.3
Methylphenidate Hydrochloride	40	4.3	4.3
Sennosides	20	4.2	4.2
Varenicline Tartrate	53	4.2	4.2
Conjugated Estrogens	38	4.1	4.1
Metoprolol Succinate	56	4.1	4.1
Divalproex Sodium	30	4.1	4.1
Canakinumab	7	4.1	4.1
Estrogens, Conjugated	38	4.1	4.1
Belimumab	20	4.0	4.0
Buprenorphine Hydrochloride, Naloxone Hydrochloride	15	3.9	3.9
Loratadine	65	3.8	3.8
Sevelamer Carbonate	7	3.8	3.8
Lisdexamfetamine Dimesylate	20	3.8	3.8
Hydromorphone Hydrochloride	55	3.8	3.8
Amphetamine	5	3.8	3.8
Thalidomide	22	3.8	3.8
Mirabegron	23	3.8	3.8
Ezetimibe	44	3.7	3.7
Diclofenac Sodium 1%	21	3.7	3.7
Diclofenac Sodium Topical	21	3.7	3.7
Diclofenac Sodium Topical Gel, 1%	21	3.7	3.7
Oxycodone Hydrochloride	123	3.7	3.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	5	3.6	3.6
Carfilzomib	16	3.6	3.6
Eszopiclone	14	3.5	3.5
Prochlorperazine Maleate	5	3.4	3.4
Zonisamide	8	3.4	3.4
Suvorexant	7	3.4	3.4
Ranitidine Hydrochloride	29	3.4	3.4
Carboxymethylcellulose Sodium	5	3.3	3.3
Armodafinil	11	3.3	3.3
Aripiprazole	63	3.3	3.3
Lacosamide	19	3.2	3.2
Tobramycin Solution	6	3.1	3.1
Drospirenone And Ethinyl Estradiol	22	3.1	3.1
Levodopa	6	3.1	3.1
Acetaminophen And Codeine	6	3.1	3.1
Carbidopa And Levodopa	23	3.1	3.1
Tobramycin Sulfate	6	3.0	3.0
Oxycodone Hydrochloride And Acetaminophen	47	3.0	3.0
Sodium Oxybate	31	3.0	3.0
Isotretinoin	23	2.9	2.9
Conjugated Estrogens And Medroxyprogesterone Acetate	11	2.9	2.9
Atomoxetine Hydrochloride	11	2.9	2.9
Morphine Sulfate	55	2.9	2.9
Testosterone Cypionate	4	2.8	2.8
Tiotropium Bromide Inhalation Spray	5	2.8	2.8
Vortioxetine	7	2.6	2.6
Daratumumab	16	2.5	2.5
Hydrocodone Bitartrate	17	2.5	2.5
Ivacaftor	3	2.4	2.4
Desvenlafaxine Succinate	10	2.3	2.3
Clozapine	46	2.3	2.3
Fingolimod Hcl	30	2.2	2.2
Ixazomib	10	2.2	2.2
Liraglutide	17	2.2	2.2
Diroximel Fumarate	4	2.1	2.1
Lurasidone Hydrochloride	7	2.1	2.1
Ethyl Alcohol	9	2.1	2.1
Copper	14	2.0	2.0
Elexacaftor, Tezacaftor, And Ivacaftor	4	2.0	2.0
Atezolizumab	12	1.9	1.9
Peginterferon Beta-1A	4	1.9	1.9
Buprenorphine	28	1.9	1.9
Medroxyprogesterone Acetate	15	1.9	1.9
Brexpiprazole	5	1.9	1.9
Dornase Alfa	5	1.6	1.6
Levonorgestrel	49	1.5	1.5
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	4	1.4	1.4
Tapentadol Hydrochloride	5	0.9	0.9
Etonogestrel	6	0.8	0.8
Valbenazine	3	0.7	0.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.