Reaction

Device Infusion Issue reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,418 reports · 131 co-occurring drugs

As of the last recalculation, Device Infusion Issue appears in 2,418 FAERS reports alongside 131 co-occurring drug terms. The strongest observed disproportionality signal is HUMAN IMMUNOGLOBULIN G (PRR 94.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Human Immunoglobulin G	207	94.4	95.3
Ketoprofen	123	85.0	85.8
Treprostinil	781	78.7	79.1
Epoprostenol	105	72.1	72.7
Amitriptyline Hydrochloride	112	57.6	57.9
Bupivacaine	54	50.9	51.2
Diphenhydramine Hydrochloride Capsule, Liquid Filled	110	46.4	46.6
0Xygen	226	43.5	43.7
Oxygen	226	43.5	43.7
Macitentan	294	41.5	41.6
Sodium Chloride Tablet	288	38.1	38.3
Sodium Chloride Tablets	288	38.1	38.3
Sodium Chloride	294	36.3	36.5
Lidocaine Hydrochloride	228	35.8	36.0
Sildenafil Powder,	132	33.7	33.8
Sildenafil	198	32.0	32.1
Clonidine	171	30.8	30.9
Riociguat	108	29.8	29.9
Adrenalinum	135	29.6	29.7
Tadalafil	286	27.8	27.8
Metolazone	35	27.2	27.3
Norepinephrine Bitartrate	44	26.8	26.9
Cetirizine Hcl	26	24.7	24.7
Lidocaine	135	21.0	21.1
Sildenafil Citrate	271	20.5	20.6
Bumetanide	61	20.4	20.4
Baclofen	181	19.5	19.5
Epinephrine	140	19.5	19.5
Lidicaine	105	19.3	19.3
Burn Relief	105	19.3	19.3
Lidocaine Hydrochloride And Epinephrine	105	19.2	19.3
Lidocaine, Menthol	106	19.2	19.2
Hydroxyzine Hydrochloride	28	18.5	18.6
Hydroxyzine Hydrochloride Oral	28	18.5	18.6
Lidocaine Hydrochloride And Epinephrine Bitartrate	105	17.7	17.7
Torsemide	66	17.6	17.6
Lidocaine 4%	106	17.5	17.5
Blinatumomab	21	17.5	17.5
Cyclobenzaprine Hydrochloride	18	17.4	17.4
Diphenhydramine	118	16.8	16.9
Ambrisentan	200	14.9	15.0
Fluticasone Propionate Nasal	49	14.2	14.2
Butalbital, Acetaminophen, And Caffeine	17	13.8	13.8
Heparin Sodium	21	13.3	13.3
Amiodarone Hydrochloride	17	13.1	13.2
Azelastine	27	13.1	13.1
Buspirone Hydrochloride	16	12.6	12.6
Potassium Chloride, Dextrose Monohydrate	121	11.8	11.8
Potassium Chloride Oral	121	11.8	11.8
Potassium Chloride Extended-Release	121	11.8	11.8
Dextrose Monohydrate	18	11.7	11.7
Dextrose	17	11.2	11.2
Potassium Chloride	136	10.8	10.8
Tiotropium Bromide Inhalation Spray	14	10.8	10.8
Diphenhydramine Hydrochloride	177	9.8	9.8
Norepinephrine	12	9.7	9.7
Atorvastatin Calcium, Film Coated	76	9.6	9.6
Selexipag	28	9.4	9.4
Fexofenadine Hcl	10	9.3	9.4
Spironolactone	144	9.3	9.3
Magnesium Sulfate Heptahydrate	14	9.3	9.3
Magnesium Sulfate	14	9.3	9.3
Pantoprazole Sodium In 0.9% Sodium Chloride	65	9.2	9.3
Pantoprazole Sodium Injection	65	9.2	9.3
Promethazine Hydrochloride	19	8.9	8.9
Diphenoxylate Hydrochloride And Atropine Sulfate	14	8.8	8.9
Magnesium Sulfate In Water For	13	8.8	8.8
Doxyclycline Hyclate	17	8.6	8.7
Rosuvastatin Calcium	28	8.6	8.7
Tizanidine Hydrochloride	18	8.6	8.6
Melatonin	53	8.5	8.6
Warfarin Sodium	44	8.3	8.3
Bosentan	46	8.0	8.0
Oxycodone And Acetaminophen Tablets	11	8.0	8.0
Dicyclomine Hydrochloride	13	7.9	7.9
Triamcinolone Acetonide Ointment Usp, 0.05%	21	7.8	7.8
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	18	7.6	7.6
Naproxen Sodium, Pseudoephedrine Hydrochloride	18	7.6	7.6
Ondansetron Hydrochloride	103	7.5	7.5
Loperamide Hydrochloride	38	7.4	7.4
Carboxymethylcellulose Sodium	8	7.3	7.4
Benzonatate	14	7.3	7.3
Fluticasone Furoate	10	7.1	7.1
Mupirocin	11	7.0	7.1
Loperamide Hydrochloride And Dimethicone	26	7.0	7.1
Magnesium	65	7.0	7.0
Mupirocin Calcium	11	6.9	6.9
Meclizine	13	6.9	6.9
Famotidine	90	6.8	6.8
Zinc	19	6.7	6.7
Zinc Chloride	19	6.6	6.6
Azithromycin	30	6.5	6.5
Triamcinolone Acetonide	23	6.5	6.5
Magnesium Oxide	31	6.4	6.5
Ferrous Sulfate	37	6.4	6.4
Biotin	23	6.4	6.4
Hydroxyzine	35	6.4	6.4
Fexofenadine Hydrochloride	16	6.4	6.4
Fluticasone Propionate	92	6.3	6.3
Azithromycin Monohydrate	30	6.3	6.3
Guaifenesin	22	6.3	6.3
Meclizine Hydrochloride	14	6.2	6.2
Gabapentin	240	6.2	6.2
Warfarin	86	6.0	6.0
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	28	5.9	5.9
Metoprolol Succinate Er Tablets	40	5.6	5.6
Levocetirizine Dihydrochloride	15	5.4	5.4
Empagliflozin	41	5.3	5.3
Loratadine Tablet	32	5.2	5.2
Loratadine Oral	29	5.1	5.1
Mometasone Furoate And Formoterol Fumarate Dihydrate	9	5.0	5.0
Budesonide, Glycopyrrolate, And Formoterol Fumarate	6	5.0	5.0
Loratadine	60	4.9	4.9
Hydromorphone Hydrochloride	51	4.9	4.9
Umeclidinium	5	4.8	4.8
Belimumab	16	4.4	4.4
Fluticasone Furoate And Vilanterol Trifenatate	18	4.3	4.3
Dofetilide	5	4.1	4.1
Oxycodone And Acetaminophen	11	4.1	4.1
Linaclotide	12	3.9	3.9
Fluorouracil Cream, 0.5%	34	3.9	3.9
Fluorouracil	34	3.8	3.8
Sevelamer Carbonate	5	3.8	3.8
Vortioxetine	7	3.5	3.5
Rimegepant Sulfate	5	3.4	3.4
Umeclidinium Bromide And Vilanterol Trifenatate	6	3.1	3.1
Acetaminophen, Aspirin (Nsaid) And Caffeine	6	3.0	3.0
Acetaminophen, Aspirin, And Caffeine	7	2.9	2.9
Brexpiprazole	5	2.6	2.6
Somatropin	15	1.8	1.8
Dornase Alfa	4	1.8	1.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.