Reaction

Expired Drug Administered reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,955 reports · 65 co-occurring drugs

As of the last recalculation, Expired Drug Administered appears in 4,955 FAERS reports alongside 65 co-occurring drug terms. The strongest observed disproportionality signal is NICOTINE POLACRILEX (PRR 13.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Nicotine Polacrilex	123	13.8	13.9
Loratadine And Pseudoephedrine Sulfate	25	13.3	13.3
Epinephrine	158	10.4	10.5
Polyethylene Glycol 3350	184	8.4	8.4
Insulin Glulisine	20	8.3	8.3
Nicotine	75	7.9	7.9
Erythropoietin	38	7.8	7.8
Acetaminophen, Aspirin, And Caffeine	37	7.4	7.4
Salmeterol Xinafoate	15	7.3	7.3
Loratadine Tablet	77	6.1	6.1
Glycerin, Lidocaine	20	6.0	6.0
Docosanol	20	5.8	5.8
Methylphenidate	39	5.7	5.7
Desvenlafaxine Succinate	35	5.5	5.5
Dorzolamide Hydrochloride And Timolol Maleate	10	5.3	5.3
Insulin Human	49	5.2	5.2
Latanoprost	60	5.1	5.1
Acetaminophen, Aspirin (Nsaid) And Caffeine	20	5.0	5.0
Ibuprofen Tablets, Coated	44	4.4	4.4
Ibuprofen Sodium	44	4.3	4.3
Valsartan And Hydrochlorothiazide	14	4.3	4.3
Loratadine	106	4.2	4.2
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	20	4.1	4.1
Naproxen Sodium, Pseudoephedrine Hydrochloride	20	4.1	4.1
Nicotine Polacrilex Mini	14	3.9	3.9
Nicotine Polarilex	14	3.9	3.9
Fesoterodine Fumarate	10	3.9	3.9
Sumatriptan	35	3.9	3.9
Ezetimibe And Simvastatin	14	3.9	3.9
Miconazole Nitrate	8	3.9	3.9
Glyburide	22	3.8	3.8
Carboxymethylcellulose Sodium	8	3.6	3.6
Liothyronine Sodium	7	3.4	3.4
Guaifenesin	24	3.3	3.3
Oseltamivir Phosphate	19	3.3	3.3
Lisinopril And Hydrochlorothiazide Tablets	6	3.2	3.2
Sildenafil Citrate	93	3.1	3.1
Ibuprofen And Diphenhydramine Citrate	17	3.1	3.1
Lisinopril And Hydrochlorothiazide	7	2.9	2.9
Conjugated Estrogens	39	2.8	2.8
Varenicline Tartrate	53	2.8	2.8
Bimatoprost	19	2.8	2.8
Estrogens, Conjugated	39	2.8	2.8
Insulin Aspart	43	2.7	2.7
Metformin Hcl	36	2.7	2.7
Insulin Lispro	88	2.7	2.7
Mometasone Furoate And Formoterol Fumarate Dihydrate	10	2.7	2.7
Olmesartan Medoxomil	22	2.6	2.6
Insulin Glargine	146	2.5	2.5
Asenapine Maleate	5	2.4	2.4
Brinzolamide	5	2.4	2.4
Brimonidine Tartrate	10	2.4	2.4
Rotigotine	8	2.3	2.3
Fluticasone Propionate And Salmeterol	23	2.3	2.3
Orlistat	14	2.3	2.3
Guanfacine	4	2.1	2.1
Ziprasidone Mesylate	7	2.1	2.1
Pioglitazone	21	2.0	2.0
Exenatide	25	2.0	2.0
Etonogestrel And Ethinyl Estradiol	10	1.9	1.9
Leuprolide Acetate	34	1.8	1.8
Teriparatide	45	1.7	1.7
Prasugrel Hydrochloride	4	1.7	1.7
Paliperidone	9	1.6	1.6
Levonorgestrel	69	1.4	1.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.