Reaction

Drug Abuser reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,147 reports · 77 co-occurring drugs

As of the last recalculation, Drug Abuser appears in 6,147 FAERS reports alongside 77 co-occurring drug terms. The strongest observed disproportionality signal is OXYCODONE HYDROCHLORIDE (PRR 55.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Oxycodone Hydrochloride	2,262	55.2	55.8
Nicotine Polacrilex	321	29.9	30.2
Carisoprodol	130	23.5	23.7
Derma Foam Excel Hand Sanitizer	36	15.3	15.4
Ethanol	36	15.3	15.3
Methadone Hydrochloride	36	11.3	11.4
Diphenhydramine Hcl	30	9.2	9.2
Alcohol	99	8.8	8.8
Nicotine Polacrilex Mini	37	8.4	8.4
Nicotine Polarilex	37	8.4	8.4
Nicotine	93	7.9	7.9
Diazepam	272	7.9	7.9
Amphetamine	19	7.8	7.8
Ethyl Alcohol	62	7.8	7.8
Isopropyl Alcohol	73	7.4	7.4
Morphine Sulfate	238	6.9	6.9
Meperidine Hydrochloride	18	6.6	6.6
Acetaminophen, Aspirin (Nsaid) And Caffeine	33	6.6	6.6
Alprazolam	365	6.3	6.3
Diazepam Oral Solution (Concentrate)	151	5.9	5.9
Diazepam Oral	151	5.9	5.9
Acetaminophen, Aspirin, And Caffeine	34	5.5	5.5
Oxycodone Hydrochloride And Acetaminophen	151	5.3	5.3
Zolpidem Tartrate	188	4.8	4.8
Tizanidine Hydrochloride	25	4.7	4.7
Olanzapine Pamoate	54	4.5	4.5
Hydrocodone Bitartrate	57	4.5	4.5
Fentanyl	124	4.3	4.3
Promethazine Hydrochloride	22	4.0	4.0
Methocarbamol	26	3.9	3.9
Temazepam	41	3.7	3.7
Oxazepam	23	3.6	3.6
Ziprasidone Mesylate	15	3.6	3.6
Oxymorphone Hydrochloride	12	3.5	3.5
Paroxetine Hydrochloride	90	3.4	3.4
Methylphenidate Hydrochloride	57	3.3	3.3
Ziprasidone	17	3.3	3.3
Morphine	71	3.2	3.3
Butalbital, Acetaminophen, And Caffeine	10	3.2	3.2
Clonazepam	145	3.1	3.1
Ketoprofen	12	3.1	3.1
Fluoxetine Hydrochloride	113	3.0	3.0
Lithium Carbonate	15	3.0	3.0
Methadone	36	2.9	2.9
Clonidine	42	2.8	2.8
Quetiapine Fumarate	23	2.6	2.6
Loratadine And Pseudoephedrine Sulfate	6	2.6	2.6
Olanzapine	79	2.5	2.5
Lopinavir And Ritonavir	10	2.5	2.5
Buspirone Hydrochloride	8	2.5	2.5
Bupropion Hydrochloride	71	2.5	2.5
Extended Phenytoin Sodium	12	2.4	2.4
Methocarbamol Tablets	12	2.4	2.4
Sertraline Hydrochloride	84	2.4	2.4
Paroxetine Hydrochloride Hemihydrate	23	2.3	2.3
Mirtazapine	63	2.3	2.3
Losartan Potassium And Hydrochlorothiazide	8	2.3	2.3
Rizatriptan Benzoate	7	2.3	2.3
Paroxetine	23	2.3	2.3
Terbinafine Hydrochloride	6	2.3	2.3
Oxycodone And Acetaminophen Tablets	8	2.3	2.3
Modafinil	21	2.2	2.2
Amlodipine Besylate And Benazepril Hydrochloride	6	2.2	2.2
Divalproex Sodium	29	2.1	2.1
Conjugated Estrogens	34	2.0	2.0
Estrogens, Conjugated	34	1.9	1.9
Hydromorphone Hydrochloride	51	1.9	1.9
Risperidone	72	1.8	1.8
Oxycodone And Acetaminophen	12	1.7	1.7
Lanreotide Acetate	4	1.7	1.7
Fentanyl Citrate	9	1.7	1.7
Pseudoephedrine Hcl	4	1.2	1.2
Glecaprevir And Pibrentasvir	3	0.9	0.9
Isotretinoin	13	0.9	0.9
Paliperidone Palmitate	8	0.8	0.8
Emicizumab	3	0.8	0.8
Buprenorphine	21	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.