Reaction

Hepatorenal Syndrome reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,674 reports · 64 co-occurring drugs

As of the last recalculation, Hepatorenal Syndrome appears in 1,674 FAERS reports alongside 64 co-occurring drug terms. The strongest observed disproportionality signal is QUININE (PRR 56.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Quinine	38	56.3	56.6
Sofosbuvir	66	43.3	43.4
Rifaximin	50	30.6	30.6
Sorafenib	48	29.6	29.6
Ursosiol	43	28.2	28.3
Ursodiol	46	27.0	27.0
Entecavir	21	22.6	22.7
Lactulose	67	22.6	22.6
Tolvaptan	23	19.9	20.0
Phytonadione	13	19.2	19.2
Spironolactone	175	17.2	17.2
Velpatasvir And Sofosbuvir	17	16.6	16.6
Ribavirin	82	16.6	16.6
Propofol	46	16.1	16.1
Busulfan	20	16.0	16.0
Daspone	12	15.4	15.4
Dapsone Gel, 5%	12	15.4	15.4
Midazolam Hydrochloride	31	14.6	14.6
Diltiazem Hydrochloride Extended-Release Tablets	13	14.3	14.3
Dapsone	12	14.1	14.1
Midazolam	28	14.0	14.0
Moxifloxacin	15	13.4	13.4
Budesonide	58	12.6	12.7
Lamivudine Oral	25	12.5	12.5
Lamivudine	30	12.3	12.3
Thiotepa	9	11.8	11.8
Basiliximab	11	11.7	11.7
Propranolol Hydrochloride	57	10.1	10.2
Tenofovir Disoproxil Fumarate Tablets	7	10.1	10.1
Clarithromycin	27	9.9	9.9
Ledipasvir And Sofosbuvir	15	9.8	9.8
Rifampin	11	9.4	9.4
Derma Foam Excel Hand Sanitizer	6	9.4	9.4
Norepinephrine	8	9.3	9.4
Ethanol	6	9.3	9.3
Pegaspargase	9	9.2	9.2
Raltegravir	12	9.1	9.1
Mesna Injection	6	9.1	9.1
Mesna	6	8.9	8.9
Norepinephrine Bitartrate	10	8.7	8.7
Rifampicin	7	8.6	8.6
Brentuximab Vedotin	7	8.5	8.5
Fentanyl Citrate	12	8.4	8.4
Cetirizine Hcl	6	8.2	8.2
Tenofovir Disoproxil Fumarate	20	7.6	7.6
Meropenem	19	7.4	7.4
Dronedarone	6	7.3	7.3
Ritonavir	17	7.3	7.3
Darunavir	8	6.6	6.6
Atezolizumab	20	6.5	6.5
Acetaminophen And Codeine	6	6.1	6.1
Peginterferon Alfa-2A	26	6.1	6.1
Gemcitabine	19	6.1	6.1
Bendamustine Hcl	7	5.6	5.6
Dolutegravir Sodium	4	5.5	5.5
Gemcitabine Hydrochloride	23	5.5	5.5
Doxorubicin	37	5.3	5.3
Ifosfamide	9	5.2	5.2
Alcohol	15	4.8	4.8
Sevoflurane	3	4.5	4.5
Durvalumab	7	4.3	4.3
Lenvatinib	11	4.2	4.2
Ethyl Alcohol	9	4.1	4.1
Encorafenib	3	3.8	3.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.