Drug

Ifosfamide

1,038 flagged reaction(s) · 69,814 total co-reports · max PRR 2,419.4

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	T-cell Lymphoma Refractory	25	2,419.4	2,422.2	signal
2	Peripheral Blood Stem Cell Apheresis	10	1,612.9	1,613.7	signal
3	Desmoplastic Small Round Cell Tumour	41	862.6	864.2	signal
4	Rhabdomyosarcoma Recurrent	20	841.5	842.3	signal
5	Rhabdoid Tumour	17	498.5	498.9	signal
6	Osteosarcoma Recurrent	18	414.8	415.1	signal
7	Haematopoietic Stem Cell Mobilisation	18	387.1	387.4	signal
8	Myelodysplastic Syndrome With Multilineage Dysplasia	13	331.1	331.3	signal
9	Leukoerythroblastosis	22	273.0	273.2	signal
10	Meningitis Tuberculous	119	263.5	265.0	signal
11	Primitive Neuroectodermal Tumour	11	253.5	253.6	signal
12	Ameloblastoma	10	230.4	230.5	signal
13	Autologous Haematopoietic Stem Cell Transplant	16	218.1	218.2	signal
14	Blood Stem Cell Transplant Failure	39	216.9	217.3	signal
15	Diffuse Large B-cell Lymphoma Refractory	165	212.1	213.7	signal
16	Ovarian Failure	92	201.9	202.8	signal
17	Encephalitis Enteroviral	16	198.5	198.7	signal
18	Synovial Sarcoma	15	181.5	181.6	signal
19	B-cell Lymphoma Refractory	14	180.6	180.8	signal
20	Pleuroparenchymal Fibroelastosis	15	165.0	165.1	signal
21	Osteosarcoma	51	150.0	150.4	signal
22	Diffuse Large B-cell Lymphoma Recurrent	283	149.1	151.1	signal
23	Malignant Transformation	57	142.9	143.3	signal
24	Nephroblastoma	15	129.6	129.7	signal
25	Osteosarcoma Metastatic	10	113.9	113.9	signal
26	Adenovirus Reactivation	13	101.5	101.5	signal
27	Salivary Gland Cancer	44	95.3	95.5	signal
28	B-cell Lymphoma Recurrent	46	91.0	91.2	signal
29	Neuroblastoma Recurrent	17	90.4	90.5	signal
30	Fanconi Syndrome	117	89.2	89.6	signal
31	Congenital Aplasia	24	88.6	88.7	signal
32	Bone Sarcoma	16	88.0	88.0	signal
33	Delayed Puberty	20	83.8	83.9	signal
34	Myeloid Leukaemia	39	82.0	82.2	signal
35	Diffuse Large B-cell Lymphoma Stage Iv	24	78.7	78.8	signal
36	Rhabdomyosarcoma	14	78.3	78.4	signal
37	Sarcoma Metastatic	10	73.9	73.9	signal
38	Anal Inflammation	42	69.5	69.6	signal
39	Adenoviral Hepatitis	15	67.8	67.9	signal
40	Refractory Cancer	14	67.7	67.8	signal
41	Pneumonia Adenoviral	12	65.6	65.6	signal
42	Follicular Lymphoma	53	65.0	65.2	signal
43	Lymphoma Transformation	22	63.7	63.8	signal
44	Aspergillus Infection	395	63.7	64.8	signal
45	Parasitic Gastroenteritis	11	60.8	60.9	signal
46	Azoospermia	22	59.0	59.0	signal
47	Metastases To Muscle	10	57.9	58.0	signal
48	Cellulitis Gangrenous	11	57.5	57.6	signal
49	Sars-cov-2 Test Negative	35	52.9	53.0	signal
50	Chromosome Analysis Abnormal	13	52.0	52.0	signal
51	Subdural Hygroma	15	50.9	51.0	signal
52	High-grade B-cell Lymphoma	9	49.2	49.2	signal
53	Marginal Zone Lymphoma	10	48.6	48.7	signal
54	Cytopenia	546	47.0	48.2	signal
55	Hepatosplenic T-cell Lymphoma	17	46.9	46.9	signal
56	Angiocentric Lymphoma	22	45.4	45.4	signal
57	Metastases To Spleen	18	44.3	44.4	signal
58	Diffuse Large B-cell Lymphoma	328	44.1	44.7	signal
59	Soft Tissue Sarcoma	15	44.0	44.0	signal
60	Metastases To Breast	14	43.8	43.9	signal
61	Transformation To Acute Myeloid Leukaemia	28	43.6	43.7	signal
62	Aplasia	85	43.6	43.8	signal
63	Neuroblastoma	16	43.4	43.4	signal
64	Febrile Neutropenia	2,701	41.7	47.6	signal
65	Myelodysplastic Syndrome	559	39.4	40.4	signal
66	Renal Tubular Disorder	107	38.5	38.7	signal
67	Tumour Compression	12	38.5	38.5	signal
68	Autoimmune Neutropenia	11	38.4	38.5	signal
69	Encephalitis Cytomegalovirus	16	37.7	37.7	signal
70	Premature Menopause	34	37.4	37.4	signal
71	Haematotoxicity	336	36.9	37.5	signal
72	Vulvovaginitis	10	34.4	34.5	signal
73	Acute Myeloid Leukaemia	527	34.4	35.2	signal
74	Neutropenic Sepsis	233	33.0	33.4	signal
75	Metastases To The Mediastinum	13	31.7	31.7	signal
76	Febrile Bone Marrow Aplasia	131	31.7	31.9	signal
77	Skin Turgor Decreased	12	31.2	31.2	signal
78	Idiopathic Pneumonia Syndrome	9	30.6	30.6	signal
79	Neoplasm Recurrence	102	30.4	30.5	signal
80	Metastases To Heart	9	29.9	29.9	signal
81	Central Nervous System Lymphoma	40	29.4	29.5	signal
82	Cystitis Haemorrhagic	116	29.2	29.3	signal
83	Vena Cava Thrombosis	48	29.1	29.2	signal
84	Pseudomonal Bacteraemia	24	28.9	28.9	signal
85	Acquired Diaphragmatic Eventration	10	28.6	28.6	signal
86	Second Primary Malignancy	234	28.4	28.7	signal
87	Mucosal Inflammation	733	28.4	29.4	signal
88	Plasmablastic Lymphoma	10	28.3	28.3	signal
89	Recall Phenomenon	23	27.8	27.8	signal
90	Klebsiella Sepsis	31	27.7	27.7	signal
91	Neutropenic Infection	26	27.1	27.1	signal
92	Acetabulum Fracture	10	26.7	26.7	signal
93	Encephalopathy	620	25.5	26.2	signal
94	Dysplasia	30	25.3	25.4	signal
95	Venoocclusive Disease	63	25.3	25.4	signal
96	Drug Clearance Decreased	31	24.8	24.8	signal
97	Angiodysplasia	9	24.7	24.8	signal
98	Fanconi Syndrome Acquired	43	24.7	24.7	signal
99	Enterobacter Sepsis	9	24.5	24.5	signal
100	Nephrogenic Diabetes Insipidus	28	24.5	24.5	signal
101	Gene Mutation	48	24.3	24.3	signal
102	Bone Marrow Toxicity	29	24.2	24.3	signal
103	Mantle Cell Lymphoma Recurrent	10	23.4	23.4	signal
104	Renal Tubular Dysfunction	13	23.4	23.4	signal
105	Ototoxicity	42	22.7	22.8	signal
106	Klebsiella Bacteraemia	21	22.7	22.7	signal
107	Renal Tubular Injury	26	22.5	22.6	signal
108	Tumour Lysis Syndrome	195	22.4	22.6	signal
109	Caecitis	10	22.0	22.0	signal
110	Metastases To Bone Marrow	11	21.9	21.9	signal
111	Human Herpesvirus 8 Infection	13	21.4	21.4	signal
112	Sarcoma	24	21.2	21.3	signal
113	Motor Developmental Delay	12	20.8	20.9	signal
114	Bone Marrow Failure	423	20.7	21.1	signal
115	Periorbital Cellulitis	11	20.6	20.6	signal
116	Peripheral T-cell Lymphoma Unspecified	12	20.5	20.5	signal
117	Neurotoxicity	354	20.4	20.7	signal
118	Cardiotoxicity	180	20.3	20.5	signal
119	Toxic Encephalopathy	100	20.3	20.4	signal
120	Body Height Below Normal	13	20.0	20.0	signal
121	Escherichia Bacteraemia	46	19.9	19.9	signal
122	Viral Haemorrhagic Cystitis	14	19.8	19.8	signal
123	Abdominal Lymphadenopathy	17	19.8	19.8	signal
124	Vasogenic Cerebral Oedema	14	19.8	19.8	signal
125	Tracheitis	15	19.8	19.8	signal
126	Acute Promyelocytic Leukaemia	20	19.6	19.6	signal
127	Angiosarcoma	9	19.4	19.4	signal
128	Ear Malformation	9	19.2	19.2	signal
129	Acute Lymphocytic Leukaemia	54	19.1	19.1	signal
130	Ovarian Disorder	18	19.0	19.0	signal
131	Systemic Candida	46	18.6	18.7	signal
132	Therapy Partial Responder	280	18.6	18.8	signal
133	Neutropenic Colitis	38	18.4	18.5	signal
134	Klebsiella Test Positive	12	18.4	18.4	signal
135	Oligohydramnios	61	18.2	18.2	signal
136	Immune Effector Cell-associated Neurotoxicity Syndrome	102	18.1	18.2	signal
137	Epstein Barr Virus Positive Mucocutaneous Ulcer	9	18.0	18.0	signal
138	Disease Progression	2,122	18.0	19.8	signal
139	Venoocclusive Liver Disease	87	17.7	17.7	signal
140	Nephropathy Toxic	197	17.7	17.8	signal
141	Cytokine Release Syndrome	330	17.3	17.5	signal
142	Scedosporium Infection	12	17.3	17.3	signal
143	Hepatitis E	27	17.2	17.2	signal
144	Engraftment Syndrome	10	17.0	17.0	signal
145	Stem Cell Transplant	42	16.9	17.0	signal
146	Graft Complication	10	16.9	16.9	signal
147	Tracheobronchitis	13	16.8	16.8	signal
148	Quadriplegia	34	16.5	16.5	signal
149	Myelopathy	31	16.2	16.3	signal
150	Pneumothorax Spontaneous	11	16.1	16.1	signal
151	Superficial Vein Thrombosis	13	16.1	16.1	signal
152	Myelosuppression	546	16.0	16.4	signal
153	Epstein-barr Virus Test Positive	10	15.9	16.0	signal
154	Metastases To Peritoneum	40	15.9	15.9	signal
155	Rectal Fissure	10	15.6	15.6	signal
156	Platelet Transfusion	20	15.6	15.6	signal
157	Acute Graft Versus Host Disease In Liver	11	15.2	15.2	signal
158	Leukoencephalopathy	57	15.2	15.2	signal
159	Hepatitis B Reactivation	48	15.0	15.1	signal
160	Hypogammaglobulinaemia	96	14.9	15.0	signal
161	Streptococcal Bacteraemia	16	14.8	14.8	signal
162	Pseudomonal Sepsis	26	14.7	14.7	signal
163	Systemic Mycosis	17	14.5	14.5	signal
164	Pancytopenia	806	14.4	14.9	signal
165	Arachnoiditis	10	14.4	14.4	signal
166	Metastases To Meninges	32	14.2	14.2	signal
167	Neutropenia	1,905	14.0	15.3	signal
168	Blood Lactate Dehydrogenase Increased	224	14.0	14.1	signal
169	Thrombocytopenia	1,548	13.8	14.8	signal
170	Intussusception	13	13.6	13.6	signal
171	Peripheral Motor Neuropathy	19	13.5	13.5	signal
172	Gastrointestinal Toxicity	64	13.5	13.6	signal
173	Cytomegalovirus Chorioretinitis	26	13.4	13.4	signal
174	Resorption Bone Increased	11	13.3	13.3	signal
175	Blood Lactate Dehydrogenase Abnormal	9	13.3	13.3	signal
176	Positron Emission Tomogram Abnormal	9	12.9	12.9	signal
177	Post-acute Covid-19 Syndrome	16	12.9	12.9	signal
178	Pulmonary Veno-occlusive Disease	9	12.8	12.9	signal
179	Foetal Growth Restriction	78	12.8	12.9	signal
180	Pyelocaliectasis	12	12.8	12.8	signal
181	Gastritis Haemorrhagic	19	12.5	12.6	signal
182	Peripheral Nerve Injury	11	12.5	12.5	signal
183	Postictal State	13	12.5	12.5	signal
184	Enterocutaneous Fistula	11	12.5	12.5	signal
185	Jc Virus Infection	20	12.4	12.4	signal
186	Metastases To Lung	144	12.4	12.5	signal
187	Sepsis Neonatal	10	12.3	12.3	signal
188	Bk Virus Infection	40	11.9	11.9	signal
189	Hypophosphataemia	87	11.8	11.8	signal
190	B-cell Lymphoma	40	11.6	11.6	signal
191	Hepatosplenomegaly	30	11.5	11.6	signal
192	Blood Fibrinogen Decreased	13	11.5	11.5	signal
193	Myelitis	18	11.5	11.5	signal
194	Pneumonia Cytomegaloviral	22	11.4	11.4	signal
195	Hyperleukocytosis	10	11.3	11.4	signal
196	Posterior Reversible Encephalopathy Syndrome	108	11.3	11.3	signal
197	Pneumonia Fungal	44	11.2	11.3	signal
198	Candida Sepsis	10	11.0	11.0	signal
199	Renal Tubular Acidosis	24	10.9	10.9	signal
200	Fungaemia	17	10.8	10.8	signal
201	Adenocarcinoma Gastric	10	10.8	10.8	signal
202	Developmental Hip Dysplasia	9	10.7	10.7	signal
203	Tumour Necrosis	11	10.4	10.4	signal
204	Pneumocystis Jirovecii Infection	12	10.3	10.3	signal
205	Hypofibrinogenaemia	10	10.2	10.2	signal
206	Neoplasm Progression	362	10.2	10.4	signal
207	Progressive Multifocal Leukoencephalopathy	84	10.1	10.1	signal
208	Tumour Haemorrhage	29	10.1	10.1	signal
209	Bone Marrow Depression	10	10.0	10.0	signal
210	Enterococcal Infection	49	10.0	10.0	signal
211	Norovirus Infection	14	10.0	10.0	signal
212	Klebsiella Infection	50	9.9	9.9	signal
213	Blood Culture Positive	30	9.8	9.8	signal
214	Hypoalbuminaemia	75	9.7	9.7	signal
215	Meningitis Bacterial	14	9.7	9.7	signal
216	Peripheral Sensory Neuropathy	57	9.7	9.7	signal
217	Demyelinating Polyneuropathy	10	9.6	9.6	signal
218	Cytogenetic Abnormality	11	9.6	9.6	signal
219	Dilated Cardiomyopathy	9	9.6	9.6	signal
220	Bacteraemia	114	9.6	9.6	signal
221	Alpha Haemolytic Streptococcal Infection	9	9.6	9.6	signal
222	Histiocytosis Haematophagic	29	9.5	9.5	signal
223	Leukopenia	479	9.5	9.7	signal
224	Diffuse Alveolar Damage	11	9.4	9.4	signal
225	Diabetes Insipidus	23	9.4	9.4	signal
226	Bacterial Sepsis	31	9.4	9.4	signal
227	Postoperative Wound Complication	12	9.3	9.3	signal
228	Abdominal Mass	25	9.3	9.3	signal
229	Acute Graft Versus Host Disease In Intestine	13	9.2	9.2	signal
230	Strongyloidiasis	15	9.2	9.2	signal
231	Pneumonia Pseudomonal	14	9.1	9.1	signal
232	Escherichia Test Positive	11	9.1	9.1	signal
233	Hearing Impaired	55	9.0	9.0	signal
234	Systemic Infection	15	8.9	8.9	signal
235	Packed Red Blood Cell Transfusion	12	8.9	8.9	signal
236	Proctalgia	57	8.8	8.8	signal
237	Glycosuria	12	8.8	8.8	signal
238	Radiation Pneumonitis	19	8.8	8.8	signal
239	Hypogonadism	9	8.7	8.7	signal
240	Metastases To Lymph Nodes	59	8.7	8.7	signal
241	Lymphoma	136	8.7	8.7	signal
242	Bronchopulmonary Aspergillosis	67	8.6	8.6	signal
243	Metastasis	62	8.5	8.6	signal
244	Streptococcal Sepsis	10	8.3	8.3	signal
245	Oesophageal Candidiasis	33	8.3	8.3	signal
246	Osteolysis	17	8.2	8.2	signal
247	Varicella Zoster Virus Infection	17	8.1	8.1	signal
248	White Blood Cell Disorder	22	8.1	8.1	signal
249	Lymphopenia	115	8.1	8.1	signal
250	Septic Shock	353	8.1	8.2	signal
251	Meningitis Cryptococcal	14	8.0	8.0	signal
252	Polyneuropathy	96	8.0	8.0	signal
253	Enterocolitis	46	8.0	8.0	signal
254	Adenovirus Infection	23	7.9	7.9	signal
255	Post Transplant Lymphoproliferative Disorder	40	7.9	7.9	signal
256	Cytomegalovirus Infection Reactivation	34	7.9	7.9	signal
257	Platelet Count Abnormal	48	7.9	7.9	signal
258	Foetal Death	41	7.8	7.8	signal
259	Sepsis	878	7.8	8.1	signal
260	Granulocyte Count Decreased	14	7.8	7.8	signal
261	Procalcitonin Increased	9	7.7	7.7	signal
262	Neutrophil Count Abnormal	22	7.7	7.7	signal
263	Osteoporotic Fracture	15	7.7	7.7	signal
264	Glomerulonephritis	19	7.7	7.7	signal
265	Mucormycosis	20	7.7	7.7	signal
266	Lung Opacity	20	7.7	7.7	signal
267	Multiple-drug Resistance	24	7.7	7.7	signal
268	Enterobacter Infection	13	7.7	7.7	signal
269	Restrictive Pulmonary Disease	9	7.6	7.6	signal
270	Pneumonia Klebsiella	14	7.6	7.6	signal
271	Cutaneous T-cell Lymphoma	9	7.5	7.5	signal
272	Acquired Gene Mutation	10	7.5	7.5	signal
273	Cytomegalovirus Infection	124	7.4	7.4	signal
274	Encephalitis Viral	9	7.3	7.3	signal
275	Haemoglobin Abnormal	47	7.3	7.3	signal
276	Blood Electrolytes Abnormal	9	7.2	7.2	signal
277	Hyperbilirubinaemia	75	7.2	7.2	signal
278	Hydronephrosis	54	7.1	7.2	signal
279	Malignant Neoplasm Progression	735	7.1	7.3	signal
280	Herpes Simplex	46	7.0	7.0	signal
281	Osteomalacia	11	7.0	7.0	signal
282	Graft Versus Host Disease	51	7.0	7.0	signal
283	Erosive Oesophagitis	12	7.0	7.0	signal
284	Clostridial Infection	24	6.9	6.9	signal
285	Bladder Spasm	13	6.9	6.9	signal
286	Lymphocytosis	15	6.9	6.9	signal
287	Papillary Thyroid Cancer	12	6.9	6.9	signal
288	Kidney Fibrosis	12	6.9	6.9	signal
289	Staphylococcal Bacteraemia	30	6.8	6.8	signal
290	Disease Recurrence	330	6.8	6.9	signal
291	Small Intestinal Perforation	13	6.8	6.8	signal
292	Escherichia Sepsis	20	6.8	6.8	signal
293	Recurrent Cancer	28	6.8	6.8	signal
294	White Blood Cell Count Abnormal	44	6.8	6.8	signal
295	Device Related Sepsis	14	6.8	6.8	signal
296	Acute Graft Versus Host Disease In Skin	19	6.8	6.8	signal
297	Epstein-barr Virus Associated Lymphoproliferative Disorder	12	6.7	6.7	signal
298	Non-hodgkin's Lymphoma	9	6.7	6.7	signal
299	Pulmonary Toxicity	47	6.6	6.6	signal
300	Clostridium Difficile Colitis	71	6.6	6.6	signal
301	Bone Marrow Disorder	20	6.6	6.6	signal
302	Immune Thrombocytopenic Purpura	19	6.5	6.5	signal
303	Neurological Decompensation	15	6.5	6.5	signal
304	Anaemia	1,258	6.5	6.9	signal
305	Malignant Pleural Effusion	11	6.5	6.5	signal
306	Hepatic Lesion	28	6.4	6.4	signal
307	Parainfluenzae Virus Infection	10	6.4	6.4	signal
308	Tubulointerstitial Nephritis	120	6.3	6.4	signal
309	Pseudomonas Infection	54	6.3	6.3	signal
310	Pneumocystis Jirovecii Pneumonia	63	6.2	6.2	signal
311	Alopecia Areata	11	6.2	6.2	signal
312	Electrolyte Imbalance	72	6.2	6.2	signal
313	Multiple Organ Dysfunction Syndrome	174	6.2	6.2	signal
314	Hepatotoxicity	137	6.1	6.1	signal
315	Graft Versus Host Disease In Gastrointestinal Tract	13	6.0	6.0	signal
316	Soft Tissue Infection	11	6.0	6.0	signal
317	Agranulocytosis	112	6.0	6.0	signal
318	Metabolic Disorder	35	5.9	6.0	signal
319	Cardiac Dysfunction	22	5.9	5.9	signal
320	Aspartate Aminotransferase Abnormal	9	5.9	5.9	signal
321	Hepatitis B	36	5.9	5.9	signal
322	Mantle Cell Lymphoma	9	5.9	5.9	signal
323	Paraplegia	17	5.8	5.8	signal
324	Left Ventricular Failure	20	5.8	5.8	signal
325	Acute Graft Versus Host Disease	27	5.8	5.8	signal
326	Capillary Leak Syndrome	12	5.8	5.8	signal
327	Therapy Non-responder	259	5.7	5.8	signal
328	Paresis	13	5.7	5.7	signal
329	Pneumothorax	92	5.7	5.7	signal
330	Ventricular Dysfunction	15	5.7	5.7	signal
331	Suspected Off Label Use	10	5.7	5.7	signal
332	Hypertransaminasaemia	39	5.6	5.7	signal
333	Bicytopenia	11	5.6	5.6	signal
334	Congestive Cardiomyopathy	24	5.6	5.6	signal
335	Foetal Distress Syndrome	12	5.6	5.6	signal
336	Acute Respiratory Distress Syndrome	100	5.6	5.6	signal
337	Staphylococcus Test Positive	12	5.6	5.6	signal
338	Candida Infection	94	5.6	5.6	signal
339	Infection	810	5.5	5.7	signal
340	Areflexia	15	5.5	5.5	signal
341	Device Related Infection	86	5.5	5.5	signal
342	Speech Disorder Developmental	16	5.5	5.5	signal
343	Haemophagocytic Lymphohistiocytosis	40	5.5	5.5	signal
344	Ejection Fraction Decreased	86	5.4	5.5	signal
345	Escherichia Infection	45	5.4	5.4	signal
346	Chronic Graft Versus Host Disease	20	5.4	5.4	signal
347	Deafness Neurosensory	18	5.4	5.4	signal
348	Clostridium Difficile Infection	119	5.4	5.4	signal
349	Hypertriglyceridaemia	32	5.4	5.4	signal
350	Cachexia	28	5.4	5.4	signal
351	Tetany	10	5.4	5.4	signal
352	Neutrophil Count Decreased	220	5.4	5.4	signal
353	Body Temperature Abnormal	10	5.3	5.3	signal
354	Covid-19 Pneumonia	64	5.3	5.3	signal
355	Brain Herniation	16	5.3	5.3	signal
356	Cardiomyopathy	79	5.3	5.3	signal
357	Metastases To Central Nervous System	68	5.2	5.2	signal
358	Hepatorenal Syndrome	9	5.2	5.2	signal
359	Lymphadenopathy Mediastinal	10	5.2	5.2	signal
360	Staphylococcal Sepsis	26	5.2	5.2	signal
361	Alanine Aminotransferase Abnormal	11	5.2	5.2	signal
362	Blood Disorder	42	5.2	5.2	signal
363	Pyelonephritis Acute	10	5.0	5.1	signal
364	Left Ventricular Dysfunction	34	5.0	5.0	signal
365	Henoch-schonlein Purpura	11	5.0	5.0	signal
366	Drug Resistance	128	4.9	4.9	signal
367	Panniculitis	12	4.9	4.9	signal
368	Lymphadenitis	12	4.9	4.9	signal
369	Aplastic Anaemia	26	4.9	4.9	signal
370	Skin Toxicity	27	4.8	4.8	signal
371	Thrombotic Thrombocytopenic Purpura	17	4.7	4.7	signal
372	Diffuse Alopecia	9	4.7	4.7	signal
373	Stomatitis	288	4.7	4.7	signal
374	Growth Retardation	14	4.7	4.7	signal
375	Embolism	39	4.6	4.6	signal
376	Urinary Tract Obstruction	11	4.6	4.6	signal
377	Epstein-barr Virus Infection	29	4.6	4.6	signal
378	Vascular Device Infection	21	4.6	4.6	signal
379	Amylase Increased	17	4.6	4.6	signal
380	Metastatic Neoplasm	20	4.6	4.6	signal
381	Papilloedema	21	4.6	4.6	signal
382	Pulmonary Haemorrhage	36	4.5	4.5	signal
383	Hypokalaemia	211	4.5	4.6	signal
384	Clostridium Test Positive	10	4.5	4.5	signal
385	Pneumatosis Intestinalis	13	4.5	4.5	signal
386	Guillain-barre Syndrome	22	4.5	4.5	signal
387	Neoplasm	52	4.4	4.5	signal
388	Metastases To Spine	15	4.4	4.4	signal
389	Meningitis Aseptic	20	4.4	4.4	signal
390	Hypernatraemia	22	4.4	4.4	signal
391	Wound Dehiscence	15	4.4	4.4	signal
392	Enteritis	28	4.3	4.3	signal
393	Ileus	54	4.3	4.3	signal
394	Granulocytopenia	25	4.3	4.3	signal
395	Ascites	128	4.3	4.3	signal
396	Hypercapnia	13	4.3	4.3	signal
397	Cytomegalovirus Viraemia	19	4.3	4.3	signal
398	Metabolic Encephalopathy	13	4.3	4.3	signal
399	Dysaesthesia	13	4.2	4.2	signal
400	Staphylococcal Infection	142	4.2	4.2	signal
401	Metastases To Liver	75	4.2	4.2	signal
402	Blood Creatine Increased	19	4.2	4.2	signal
403	Dilatation Ventricular	9	4.2	4.2	signal
404	Fibrosis	13	4.2	4.2	signal
405	Mycobacterium Avium Complex Infection	11	4.1	4.1	signal
406	Necrosis	23	4.0	4.1	signal
407	Lymphoproliferative Disorder	12	4.0	4.0	signal
408	Cerebellar Syndrome	9	4.0	4.0	signal
409	Lymphadenopathy	142	3.9	4.0	signal
410	Escherichia Urinary Tract Infection	17	3.9	3.9	signal
411	Pneumocystis Jiroveci Pneumonia	9	3.9	3.9	signal
412	Lung Infiltration	35	3.9	3.9	signal
413	Candidiasis	16	3.9	3.9	signal
414	Thrombotic Microangiopathy	38	3.9	3.9	signal
415	Acidosis	30	3.9	3.9	signal
416	Small Intestinal Obstruction	48	3.9	3.9	signal
417	Lung Consolidation	11	3.9	3.9	signal
418	Urosepsis	36	3.8	3.8	signal
419	Product Use In Unapproved Indication	953	3.8	4.0	signal
420	Acute Febrile Neutrophilic Dermatosis	9	3.8	3.8	signal
421	Haemangioma	9	3.8	3.8	signal
422	Haematological Infection	9	3.8	3.8	signal
423	Respiratory Failure	282	3.8	3.8	signal
424	Spinal Cord Compression	15	3.8	3.8	signal
425	Respiratory Acidosis	15	3.8	3.8	signal
426	Hypomagnesaemia	53	3.8	3.8	signal
427	Gastrointestinal Necrosis	11	3.7	3.7	signal
428	Atrial Fibrillation	368	3.7	3.8	signal
429	Azotaemia	15	3.7	3.7	signal
430	Bacterial Infection	69	3.7	3.7	signal
431	Stupor	12	3.7	3.7	signal
432	Rhinovirus Infection	14	3.6	3.6	signal
433	Systemic Inflammatory Response Syndrome	14	3.6	3.6	signal
434	Normochromic Normocytic Anaemia	11	3.6	3.6	signal
435	Cerebral Ischaemia	19	3.6	3.6	signal
436	Skin Necrosis	19	3.6	3.6	signal
437	Transaminases Increased	81	3.6	3.6	signal
438	Platelet Count Decreased	388	3.6	3.6	signal
439	Subdural Haemorrhage	10	3.6	3.6	signal
440	Oral Candidiasis	47	3.6	3.6	signal
441	Coagulopathy	60	3.6	3.6	signal
442	Red Cell Distribution Width Increased	15	3.6	3.6	signal
443	Leukaemia	34	3.5	3.6	signal
444	Monocyte Count Increased	13	3.5	3.5	signal
445	Haemorrhage	372	3.5	3.5	signal
446	Platelet Disorder	9	3.5	3.5	signal
447	Anal Abscess	19	3.5	3.5	signal
448	Inappropriate Antidiuretic Hormone Secretion	36	3.5	3.5	signal
449	Haemodialysis	30	3.5	3.5	signal
450	Autoimmune Haemolytic Anaemia	12	3.5	3.5	signal
451	Atelectasis	34	3.5	3.5	signal
452	Mean Cell Volume Increased	9	3.4	3.5	signal
453	Blood Creatinine Abnormal	12	3.4	3.4	signal
454	Acute Lymphocytic Leukaemia Recurrent	9	3.4	3.4	signal
455	Pneumonitis	94	3.4	3.4	signal
456	Deafness	90	3.4	3.4	signal
457	Ventricular Hypokinesia	11	3.4	3.4	signal
458	Disseminated Intravascular Coagulation	48	3.3	3.4	signal
459	Liver Abscess	11	3.3	3.3	signal
460	Lymphocyte Count Decreased	60	3.3	3.3	signal
461	Fibrin D Dimer Increased	12	3.3	3.3	signal
462	Chronic Lymphocytic Leukaemia	16	3.3	3.3	signal
463	Atypical Pneumonia	10	3.3	3.3	signal
464	Malnutrition	37	3.3	3.3	signal
465	Cardiac Failure Acute	22	3.3	3.3	signal
466	White Blood Cell Count Decreased	359	3.3	3.3	signal
467	Myelofibrosis	10	3.2	3.2	signal
468	Blood Phosphorus Decreased	12	3.2	3.2	signal
469	Hypocalcaemia	62	3.2	3.2	signal
470	Drug Ineffective For Unapproved Indication	183	3.2	3.2	signal
471	Hepatic Failure	99	3.2	3.2	signal
472	Accident	39	3.2	3.2	signal
473	Pleural Effusion	199	3.2	3.2	signal
474	Colitis	123	3.2	3.2	signal
475	Pyelonephritis	28	3.2	3.2	signal
476	Premature Baby	98	3.2	3.2	signal
477	Off Label Use	2,816	3.2	3.5	signal
478	Mental Status Changes	90	3.2	3.2	signal
479	Brain Death	10	3.2	3.2	signal
480	Diverticulum Intestinal	14	3.2	3.2	signal
481	Small For Dates Baby	16	3.2	3.2	signal
482	Oesophagitis	35	3.1	3.2	signal
483	Electroencephalogram Abnormal	10	3.1	3.1	signal
484	C-reactive Protein Increased	115	3.1	3.1	signal
485	Hypercalcaemia	39	3.1	3.1	signal
486	Premature Labour	18	3.1	3.1	signal
487	Pneumonia Viral	10	3.1	3.1	signal
488	Immune Thrombocytopenia	14	3.1	3.1	signal
489	Drug Toxicity	43	3.1	3.1	signal
490	Mixed Liver Injury	9	3.0	3.0	signal
491	Nervous System Disorder	96	3.0	3.0	signal
492	Inflammatory Marker Increased	15	3.0	3.0	signal
493	Abscess Limb	13	3.0	3.0	signal
494	Renal Impairment	253	3.0	3.0	signal
495	Low Birth Weight Baby	24	3.0	3.0	signal
496	Acute Kidney Injury	459	3.0	3.0	signal
497	Angiopathy	17	3.0	3.0	signal
498	Immunosuppression	26	2.9	2.9	signal
499	Neurological Symptom	17	2.9	2.9	signal
500	Neuropathy Peripheral	281	2.9	2.9	signal
501	Haemorrhoids	58	2.9	2.9	signal
502	Multi-organ Failure	52	2.9	2.9	signal
503	Hepatic Cyst	10	2.9	2.9	signal
504	Catheter Site Infection	11	2.9	2.9	signal
505	Body Temperature Increased	60	2.9	2.9	signal
506	Hyperuricaemia	12	2.9	2.9	signal
507	Proteinuria	55	2.9	2.9	signal
508	Pyrexia	1,006	2.9	2.9	signal
509	Hyperpyrexia	12	2.8	2.8	signal
510	Haemolytic Anaemia	26	2.8	2.8	signal
511	Stillbirth	14	2.8	2.8	signal
512	Hypophagia	73	2.8	2.8	signal
513	Acute Hepatic Failure	39	2.8	2.8	signal
514	Hyperreflexia	10	2.8	2.8	signal
515	Urine Output Decreased	25	2.8	2.8	signal
516	Myoclonus	34	2.8	2.8	signal
517	Renal Tubular Necrosis	28	2.8	2.8	signal
518	Pneumonia Bacterial	26	2.8	2.8	signal
519	Blood Creatinine Increased	186	2.8	2.8	signal
520	Alanine Aminotransferase Increased	174	2.8	2.8	signal
521	Thrombophlebitis	10	2.8	2.8	signal
522	Premature Delivery	45	2.8	2.8	signal
523	Cardiopulmonary Failure	11	2.8	2.8	signal
524	Localised Oedema	13	2.8	2.8	signal
525	Prostatomegaly	11	2.8	2.8	signal
526	Portal Vein Thrombosis	9	2.7	2.7	signal
527	Venous Thrombosis	11	2.7	2.7	signal
528	Intestinal Perforation	31	2.7	2.7	signal
529	Monoplegia	12	2.7	2.7	signal
530	Oliguria	17	2.7	2.7	signal
531	Thrombocytosis	10	2.7	2.7	signal
532	Tachypnoea	37	2.7	2.7	signal
533	Hypovolaemic Shock	13	2.7	2.7	signal
534	Cardiac Tamponade	13	2.7	2.7	signal
535	Hypervolaemia	13	2.7	2.7	signal
536	Generalised Tonic-clonic Seizure	44	2.6	2.6	signal
537	Myositis	24	2.6	2.6	signal
538	Retinal Haemorrhage	19	2.6	2.6	signal
539	Lung Infection	42	2.6	2.6	signal
540	Respiratory Syncytial Virus Infection	23	2.6	2.6	signal
541	Dermatitis Bullous	19	2.6	2.6	signal
542	Encephalitis	18	2.6	2.6	signal
543	Treatment Failure	213	2.6	2.6	signal
544	Hepatic Function Abnormal	96	2.5	2.6	signal
545	Activated Partial Thromboplastin Time Prolonged	13	2.5	2.5	signal
546	Haematuria	87	2.5	2.5	signal
547	Haemodynamic Instability	19	2.5	2.5	signal
548	Facial Paresis	9	2.5	2.5	signal
549	Pericardial Effusion	58	2.5	2.5	signal
550	Partial Seizures	13	2.5	2.5	signal
551	Hypoxia	88	2.5	2.5	signal
552	Gastric Ulcer Haemorrhage	14	2.5	2.5	signal
553	Splenomegaly	29	2.4	2.4	signal
554	Appendicitis	23	2.4	2.4	signal
555	Sinus Tachycardia	35	2.4	2.4	signal
556	Faecal Incontinence	12	2.4	2.4	signal
557	Toxicity To Various Agents	412	2.4	2.4	signal
558	Acute Respiratory Failure	47	2.4	2.4	signal
559	Organising Pneumonia	12	2.4	2.4	signal
560	Leukocytosis	44	2.4	2.4	signal
561	Chemotherapy	9	2.4	2.4	signal
562	Herpes Virus Infection	14	2.4	2.4	signal
563	Renal Function Test Abnormal	11	2.4	2.4	signal
564	Disorientation	95	2.4	2.4	signal
565	Transfusion	25	2.3	2.3	signal
566	Cardiac Failure Chronic	10	2.3	2.3	signal
567	Mouth Ulceration	49	2.3	2.3	signal
568	Sarcoidosis	11	2.3	2.3	signal
569	Catatonia	12	2.3	2.3	signal
570	Mitral Valve Incompetence	26	2.3	2.3	signal
571	Haemoglobin Decreased	234	2.2	2.2	signal
572	Purpura	20	2.2	2.2	signal
573	Serotonin Syndrome	43	2.2	2.2	signal
574	Meningitis	15	2.2	2.2	signal
575	Grand Mal Convulsion	21	2.2	2.2	signal
576	Urinary Tract Disorder	10	2.2	2.2	signal
577	Fungal Infection	74	2.2	2.2	signal
578	Aspartate Aminotransferase Increased	118	2.2	2.2	signal
579	Hydrocephalus	12	2.2	2.2	signal
580	Ataxia	26	2.1	2.1	signal
581	Altered State Of Consciousness	47	2.1	2.1	signal
582	Palmar-plantar Erythrodysaesthesia Syndrome	51	2.1	2.1	signal
583	Disease Complication	10	2.1	2.1	signal
584	Gastrointestinal Perforation	9	2.1	2.1	signal
585	Renal Failure Acute	93	2.1	2.1	signal
586	Arthritis Infective	10	2.1	2.1	signal
587	Subarachnoid Haemorrhage	22	2.1	2.1	signal
588	Performance Status Decreased	10	2.1	2.1	signal
589	Metabolic Acidosis	67	2.1	2.1	signal
590	Lipase Increased	16	2.1	2.1	signal
591	Shock Haemorrhagic	17	2.1	2.1	signal
592	Renal Failure	279	2.0	2.1	signal
593	Visual Field Defect	15	2.0	2.0	signal
594	Postoperative Wound Infection	14	2.0	2.0	signal
595	Nystagmus	11	2.0	2.0	signal
596	Respiratory Distress	57	2.0	2.0	signal
597	Ecchymosis	14	2.0	2.0	signal
598	Nephropathy	19	2.0	2.0	no signal
599	Blood Albumin Decreased	16	2.0	2.0	no signal
600	Haemorrhage Intracranial	30	2.0	2.0	no signal
601	Poisoning	25	1.9	1.9	no signal
602	Hepatic Cytolysis	24	1.9	1.9	no signal
603	Pulmonary Alveolar Haemorrhage	11	1.9	1.9	no signal
604	Skin Mass	13	1.9	1.9	no signal
605	Metastases To Bone	32	1.9	1.9	no signal
606	Status Epilepticus	22	1.9	1.9	no signal
607	Hyponatraemia	109	1.9	1.9	no signal
608	Erythema Multiforme	18	1.9	1.9	no signal
609	Circulatory Collapse	33	1.9	1.9	no signal
610	Mass	27	1.9	1.9	no signal
611	Petechiae	20	1.9	1.9	no signal
612	Cardiac Failure	153	1.9	1.9	no signal
613	Thyroid Cancer	23	1.9	1.9	no signal
614	Blood Bilirubin Increased	51	1.8	1.9	no signal
615	Pulmonary Mass	28	1.8	1.9	no signal
616	Hemiparesis	32	1.8	1.8	no signal
617	Odynophagia	11	1.8	1.8	no signal
618	Osteonecrosis	61	1.8	1.8	no signal
619	Tachycardia	163	1.8	1.8	no signal
620	Pulmonary Oedema	82	1.8	1.8	no signal
621	Cardiogenic Shock	26	1.8	1.8	no signal
622	Blood Alkaline Phosphatase Increased	45	1.8	1.8	no signal
623	Deep Vein Thrombosis	117	1.8	1.8	no signal
624	Dermatitis	37	1.8	1.8	no signal
625	Product Use Issue	332	1.7	1.8	no signal
626	Pathological Fracture	9	1.7	1.7	no signal
627	Therapeutic Product Effect Incomplete	125	1.7	1.7	no signal
628	Cholecystitis	21	1.7	1.7	no signal
629	Hepatocellular Injury	25	1.7	1.7	no signal
630	Abscess	28	1.7	1.7	no signal
631	Neutrophil Count Increased	18	1.7	1.7	no signal
632	Wound Infection	19	1.7	1.7	no signal
633	Brain Oedema	22	1.7	1.7	no signal
634	Amenorrhoea	29	1.7	1.7	no signal
635	Anuria	15	1.7	1.7	no signal
636	Hiccups	14	1.7	1.7	no signal
637	Asphyxia	14	1.7	1.7	no signal
638	Shock	39	1.7	1.7	no signal
639	Immunodeficiency	25	1.7	1.7	no signal
640	Live Birth	14	1.7	1.7	no signal
641	Drug Interaction	264	1.6	1.6	no signal
642	Central Nervous System Lesion	23	1.6	1.6	no signal
643	Hepatitis	42	1.6	1.6	no signal
644	Respiratory Disorder	49	1.6	1.6	no signal
645	Skin Hyperpigmentation	14	1.6	1.6	no signal
646	Vomiting	758	1.6	1.6	no signal
647	Intracranial Pressure Increased	9	1.6	1.6	no signal
648	Gamma-glutamyltransferase Increased	35	1.5	1.6	no signal
649	Cholestasis	30	1.5	1.5	no signal
650	Generalised Oedema	19	1.5	1.5	no signal
651	Gastrointestinal Inflammation	12	1.5	1.5	no signal
652	Incoherent	10	1.5	1.5	no signal
653	Confusional State	248	1.5	1.5	no signal
654	Toxic Epidermal Necrolysis	23	1.5	1.5	no signal
655	Aphasia	46	1.5	1.5	no signal
656	Therapeutic Response Decreased	91	1.5	1.5	no signal
657	Adrenal Insufficiency	18	1.5	1.5	no signal
658	Intentional Product Use Issue	132	1.5	1.5	no signal
659	Hepatitis Cholestatic	9	1.5	1.5	no signal
660	Coronavirus Infection	10	1.5	1.5	no signal
661	Blood Urea Increased	25	1.5	1.5	no signal
662	Delirium	51	1.4	1.4	no signal
663	Inguinal Hernia	9	1.4	1.4	no signal
664	Oral Pain	33	1.4	1.4	no signal
665	Hyperglycaemia	53	1.4	1.4	no signal
666	Concomitant Disease Aggravated	9	1.4	1.4	no signal
667	No Therapeutic Response	18	1.4	1.4	no signal
668	Pneumonia	459	1.4	1.4	no signal
669	Right Ventricular Failure	10	1.4	1.4	no signal
670	Renal Failure Chronic	11	1.4	1.4	no signal
671	C-reactive Protein Abnormal	9	1.4	1.4	no signal
672	Blood Potassium Decreased	42	1.4	1.4	no signal
673	Subdural Haematoma	20	1.4	1.4	no signal
674	Diarrhoea Haemorrhagic	13	1.4	1.4	no signal
675	Cellulitis	70	1.4	1.4	no signal
676	Epistaxis	104	1.4	1.4	no signal
677	Toxic Skin Eruption	14	1.4	1.4	no signal
678	Urinary Incontinence	41	1.4	1.4	no signal
679	Renal Cyst	11	1.4	1.4	no signal
680	Atrial Flutter	11	1.3	1.3	no signal
681	Gastroenteritis	20	1.3	1.3	no signal
682	Interstitial Lung Disease	66	1.3	1.3	no signal
683	Caesarean Section	16	1.3	1.3	no signal
684	Pulmonary Hypertension	28	1.3	1.3	no signal
685	Covid-19	236	1.3	1.3	no signal
686	Troponin Increased	10	1.3	1.3	no signal
687	Skin Lesion	36	1.3	1.3	no signal
688	Hyperthermia	10	1.3	1.3	no signal
689	Paralysis	19	1.3	1.3	no signal
690	Developmental Delay	12	1.3	1.3	no signal
691	Hepatomegaly	13	1.3	1.3	no signal
692	Optic Neuritis	12	1.3	1.3	no signal
693	Maternal Exposure During Pregnancy	116	1.3	1.3	no signal
694	Cerebral Haemorrhage	47	1.3	1.3	no signal
695	Osteopenia	20	1.3	1.3	no signal
696	Rash Maculo-papular	29	1.3	1.3	no signal
697	Chills	153	1.3	1.3	no signal
698	Motor Dysfunction	13	1.3	1.3	no signal
699	Intestinal Obstruction	48	1.3	1.3	no signal
700	Neuralgia	31	1.3	1.3	no signal
701	Seizure	146	1.2	1.3	no signal
702	Drug Effective For Unapproved Indication	37	1.2	1.2	no signal
703	Haematemesis	32	1.2	1.2	no signal
704	Decreased Appetite	286	1.2	1.2	no signal
705	Platelet Count Increased	16	1.2	1.2	no signal
706	Hypotension	245	1.2	1.2	no signal
707	Polyuria	10	1.2	1.2	no signal
708	Coma	58	1.2	1.2	no signal
709	Drug Ineffective	1,597	1.2	1.2	no signal
710	Lower Gastrointestinal Haemorrhage	9	1.2	1.2	no signal
711	Pancreatitis Acute	27	1.2	1.2	no signal
712	Peritonitis	25	1.2	1.2	no signal
713	Pharyngitis	15	1.2	1.2	no signal
714	Medical Device Complication	9	1.2	1.2	no signal
715	Liver Injury	29	1.2	1.2	no signal
716	Hypotonia	12	1.2	1.2	no signal
717	Dialysis	17	1.2	1.2	no signal
718	Nerve Compression	11	1.2	1.2	no signal
719	Atrial Septal Defect	10	1.2	1.2	no signal
720	Upper Gastrointestinal Haemorrhage	20	1.2	1.2	no signal
721	Pulmonary Embolism	113	1.2	1.2	no signal
722	Hepatic Encephalopathy	11	1.2	1.2	no signal
723	Unresponsive To Stimuli	30	1.1	1.1	no signal
724	Hypothyroidism	37	1.1	1.1	no signal
725	Congenital Anomaly	9	1.1	1.1	no signal
726	Gastrointestinal Haemorrhage	97	1.1	1.1	no signal
727	Haematocrit Decreased	23	1.1	1.1	no signal
728	Jaundice	31	1.1	1.1	no signal
729	Bone Pain	67	1.1	1.1	no signal
730	End Stage Renal Disease	21	1.1	1.1	no signal
731	Anaphylactic Shock	29	1.1	1.1	no signal
732	Sudden Death	12	1.1	1.1	no signal
733	Night Sweats	36	1.1	1.1	no signal
734	Rhinitis	9	1.1	1.1	no signal
735	Presyncope	27	1.1	1.1	no signal
736	Vasculitis	13	1.1	1.1	no signal
737	Dehydration	148	1.1	1.1	no signal
738	Aspiration	12	1.1	1.1	no signal
739	Hallucination, Visual	23	1.1	1.1	no signal
740	Full Blood Count Decreased	22	1.1	1.1	no signal
741	Drug Level Increased	18	1.1	1.1	no signal
742	Cardiac Arrest	90	1.1	1.1	no signal
743	Urinary Retention	36	1.1	1.1	no signal
744	Oral Herpes	21	1.1	1.1	no signal
745	Respiratory Tract Infection	28	1.1	1.1	no signal
746	Skin Infection	12	1.1	1.1	no signal
747	Folliculitis	11	1.0	1.0	no signal
748	Abdominal Pain	247	1.0	1.0	no signal
749	Myocarditis	12	1.0	1.0	no signal
750	Ill-defined Disorder	64	1.0	1.0	no signal
751	Drug Intolerance	101	1.0	1.0	no signal
752	Epilepsy	32	1.0	1.0	no signal
753	Cardiomegaly	13	1.0	1.0	no signal
754	Blood Magnesium Decreased	9	1.0	1.0	no signal
755	Hallucination	78	1.0	1.0	no signal
756	Convulsion	60	1.0	1.0	no signal
757	Decreased Activity	11	1.0	1.0	no signal
758	Red Blood Cell Count Decreased	29	1.0	1.0	no signal
759	Dyspnoea Exertional	38	1.0	1.0	no signal
760	Blood Sodium Decreased	19	1.0	1.0	no signal
761	Dysphagia	95	1.0	1.0	no signal
762	Cognitive Disorder	46	1.0	1.0	no signal
763	Gastrointestinal Disorder	87	1.0	1.0	no signal
764	Diarrhoea	633	1.0	1.0	no signal
765	General Physical Health Deterioration	113	1.0	1.0	no signal
766	Tooth Abscess	10	1.0	1.0	no signal
767	Blood Calcium Decreased	11	1.0	1.0	no signal
768	Herpes Zoster	56	1.0	1.0	no signal
769	Skin Ulcer	25	1.0	1.0	no signal
770	Agitation	71	0.9	0.9	no signal
771	Tinnitus	44	0.9	0.9	no signal
772	Gingival Bleeding	13	0.9	0.9	no signal
773	Full Blood Count Abnormal	10	0.9	0.9	no signal
774	Nausea	746	0.9	0.9	no signal
775	Gastric Ulcer	18	0.9	0.9	no signal
776	Supraventricular Tachycardia	9	0.9	0.9	no signal
777	Drug-induced Liver Injury	29	0.9	0.9	no signal
778	Breast Pain	10	0.9	0.9	no signal
779	Mydriasis	12	0.9	0.9	no signal
780	White Blood Cell Count Increased	36	0.9	0.9	no signal
781	Pelvic Pain	17	0.9	0.9	no signal
782	Product Prescribing Issue	19	0.9	0.9	no signal
783	Dystonia	18	0.9	0.9	no signal
784	Constipation	198	0.9	0.9	no signal
785	Depressed Level Of Consciousness	36	0.9	0.9	no signal
786	Glomerular Filtration Rate Decreased	11	0.9	0.9	no signal
787	Musculoskeletal Chest Pain	14	0.9	0.9	no signal
788	Renal Injury	27	0.9	0.9	no signal
789	Obstructive Airways Disorder	10	0.9	0.9	no signal
790	Emphysema	9	0.9	0.9	no signal
791	Rhabdomyolysis	37	0.9	0.9	no signal
792	Ulcer	14	0.9	0.9	no signal
793	Liver Disorder	38	0.8	0.8	no signal
794	Tuberculosis	11	0.8	0.8	no signal
795	Oedema	46	0.8	0.8	no signal
796	Incontinence	9	0.8	0.8	no signal
797	Ischaemic Stroke	15	0.8	0.8	no signal
798	Pulmonary Fibrosis	16	0.8	0.8	no signal
799	Hypercholesterolaemia	8	0.8	0.8	no signal
800	International Normalised Ratio Increased	24	0.8	0.8	no signal
801	Affect Lability	8	0.8	0.8	no signal
802	Face Oedema	14	0.8	0.8	no signal
803	Pulmonary Arterial Hypertension	12	0.8	0.8	no signal
804	Liver Function Test Abnormal	24	0.8	0.8	no signal
805	Fluid Overload	12	0.8	0.8	no signal
806	Foetal Exposure During Pregnancy	66	0.8	0.8	no signal
807	Pneumonia Aspiration	20	0.8	0.8	no signal
808	Lethargy	46	0.8	0.8	no signal
809	Gastritis	21	0.8	0.8	no signal
810	Inflammation	41	0.8	0.8	no signal
811	Chronic Kidney Disease	61	0.8	0.8	no signal
812	Eating Disorder	17	0.8	0.8	no signal
813	Thrombosis	64	0.8	0.8	no signal
814	Hypothermia	8	0.8	0.8	no signal
815	Exposure During Pregnancy	49	0.8	0.8	no signal
816	Haemoptysis	22	0.8	0.8	no signal
817	Eyelid Ptosis	8	0.8	0.8	no signal
818	Anaphylactic Reaction	43	0.8	0.8	no signal
819	Syncope	78	0.8	0.8	no signal
820	Anorexia	10	0.8	0.8	no signal
821	Neoplasm Malignant	51	0.8	0.7	no signal
822	Cyanosis	12	0.7	0.7	no signal
823	Upper Respiratory Tract Infection	35	0.7	0.7	no signal
824	Arrhythmia	36	0.7	0.7	no signal
825	Drug Effect Incomplete	27	0.7	0.7	no signal
826	Dysuria	27	0.7	0.7	no signal
827	Viral Infection	24	0.7	0.7	no signal
828	Cystitis	23	0.7	0.7	no signal
829	Parkinsonism	7	0.7	0.7	no signal
830	Lung Disorder	35	0.7	0.7	no signal
831	Eye Infection	8	0.7	0.7	no signal
832	Infusion Related Reaction	47	0.7	0.7	no signal
833	Psychotic Disorder	21	0.7	0.7	no signal
834	Delusion	11	0.7	0.7	no signal
835	Renal Disorder	33	0.7	0.7	no signal
836	Salivary Hypersecretion	7	0.7	0.7	no signal
837	Mental Impairment	17	0.7	0.7	no signal
838	Weight Decreased	195	0.7	0.7	no signal
839	Asthenia	262	0.7	0.7	no signal
840	Lactic Acidosis	22	0.7	0.7	no signal
841	Melaena	15	0.7	0.7	no signal
842	Death	577	0.7	0.6	no signal
843	Electrocardiogram Qt Prolonged	24	0.7	0.7	no signal
844	Dyskinesia	27	0.7	0.7	no signal
845	Iron Deficiency Anaemia	6	0.6	0.6	no signal
846	Respiratory Depression	8	0.6	0.6	no signal
847	Feeding Disorder	13	0.6	0.6	no signal
848	Alopecia	128	0.6	0.6	no signal
849	Hepatic Enzyme Increased	44	0.6	0.6	no signal
850	Pancreatitis	34	0.6	0.6	no signal
851	Flank Pain	6	0.6	0.6	no signal
852	Drug Exposure During Pregnancy	22	0.6	0.6	no signal
853	Dental Caries	7	0.6	0.6	no signal
854	Abdominal Pain Lower	16	0.6	0.6	no signal
855	Stevens-johnson Syndrome	14	0.6	0.6	no signal
856	Condition Aggravated	189	0.6	0.6	no signal
857	Diplopia	16	0.6	0.6	no signal
858	Nodule	8	0.6	0.6	no signal
859	Osteomyelitis	11	0.6	0.6	no signal
860	Ventricular Tachycardia	10	0.6	0.6	no signal
861	Colon Cancer	9	0.6	0.6	no signal
862	Conjunctivitis	11	0.6	0.6	no signal
863	Bone Disorder	11	0.6	0.6	no signal
864	Brain Injury	6	0.6	0.6	no signal
865	Malignant Melanoma	8	0.6	0.6	no signal
866	Movement Disorder	19	0.6	0.6	no signal
867	Oedema Peripheral	72	0.6	0.6	no signal
868	Pallor	16	0.6	0.6	no signal
869	Blood Count Abnormal	9	0.6	0.6	no signal
870	Osteoporosis	24	0.6	0.6	no signal
871	Somnolence	116	0.6	0.6	no signal
872	Acute Myocardial Infarction	17	0.6	0.6	no signal
873	Hepatitis C	7	0.6	0.6	no signal
874	Cerebral Infarction	14	0.6	0.6	no signal
875	Post Procedural Complication	11	0.6	0.6	no signal
876	Wrong Technique In Drug Usage Process	21	0.6	0.6	no signal
877	Loss Of Consciousness	73	0.6	0.6	no signal
878	Skin Reaction	8	0.6	0.6	no signal
879	Blindness	23	0.6	0.6	no signal
880	Transient Ischaemic Attack	19	0.6	0.5	no signal
881	Breast Cancer Metastatic	6	0.5	0.5	no signal
882	Extrapyramidal Disorder	14	0.5	0.5	no signal
883	Rash Erythematous	26	0.5	0.5	no signal
884	Bradycardia	29	0.5	0.5	no signal
885	Productive Cough	25	0.5	0.5	no signal
886	Spinal Disorder	5	0.5	0.5	no signal
887	Sars-cov-2 Test Positive	7	0.5	0.5	no signal
888	Pharyngeal Swelling	5	0.5	0.5	no signal
889	Disturbance In Attention	28	0.5	0.5	no signal
890	Sinus Bradycardia	5	0.5	0.5	no signal
891	Orthostatic Hypotension	9	0.5	0.5	no signal
892	Eyelid Oedema	6	0.5	0.5	no signal
893	Cold Sweat	9	0.5	0.5	no signal
894	Oxygen Saturation Decreased	28	0.5	0.5	no signal
895	Abnormal Behaviour	20	0.5	0.5	no signal
896	Drug Effect Less Than Expected	7	0.5	0.5	no signal
897	Sensory Disturbance	8	0.5	0.5	no signal
898	Pregnancy	10	0.5	0.5	no signal
899	Bronchospasm	7	0.5	0.5	no signal
900	Cholelithiasis	16	0.5	0.5	no signal
901	Hyperkalaemia	17	0.5	0.5	no signal
902	Dyspnoea	274	0.5	0.5	no signal
903	Pericarditis	8	0.5	0.5	no signal
904	Psychomotor Hyperactivity	8	0.5	0.5	no signal
905	Back Pain	111	0.5	0.5	no signal
906	Erythema	98	0.5	0.5	no signal
907	Meningioma	7	0.5	0.5	no signal
908	Hypoglycaemia	23	0.5	0.5	no signal
909	Hypertension	99	0.5	0.5	no signal
910	Adverse Event	43	0.5	0.5	no signal
911	Oropharyngeal Pain	43	0.5	0.5	no signal
912	Chest Pain	82	0.4	0.4	no signal
913	Hallucination, Auditory	7	0.4	0.4	no signal
914	No Adverse Event	78	0.4	0.4	no signal
915	Myocardial Ischaemia	5	0.4	0.4	no signal
916	Blood Glucose Abnormal	8	0.4	0.4	no signal
917	Blister	24	0.4	0.4	no signal
918	Cardio-respiratory Arrest	18	0.4	0.4	no signal
919	Coordination Abnormal	6	0.4	0.4	no signal
920	Fracture	8	0.4	0.4	no signal
921	Fatigue	324	0.4	0.4	no signal
922	Blood Pressure Decreased	27	0.4	0.4	no signal
923	Speech Disorder	21	0.4	0.4	no signal
924	Chromaturia	9	0.4	0.4	no signal
925	Cough	111	0.4	0.4	no signal
926	Impaired Healing	13	0.4	0.4	no signal
927	Cardiac Disorder	37	0.4	0.4	no signal
928	Muscle Twitching	9	0.4	0.4	no signal
929	Urinary Tract Infection	66	0.4	0.4	no signal
930	Paraesthesia	61	0.4	0.4	no signal
931	Chest Discomfort	39	0.4	0.4	no signal
932	Restlessness	14	0.4	0.4	no signal
933	Adverse Reaction	5	0.4	0.4	no signal
934	Vaginal Haemorrhage	16	0.4	0.4	no signal
935	Musculoskeletal Disorder	7	0.4	0.4	no signal
936	Abdominal Distension	38	0.4	0.4	no signal
937	Diverticulitis	10	0.4	0.4	no signal
938	Hypertensive Crisis	4	0.4	0.4	no signal
939	Rash	154	0.3	0.3	no signal
940	Erectile Dysfunction	9	0.3	0.3	no signal
941	Dysarthria	13	0.3	0.3	no signal
942	Muscle Rigidity	4	0.3	0.3	no signal
943	Cardiac Failure Congestive	27	0.3	0.3	no signal
944	Skin Disorder	11	0.3	0.3	no signal
945	Pain In Extremity	95	0.3	0.3	no signal
946	Gynaecomastia	10	0.3	0.3	no signal
947	Pain	196	0.3	0.3	no signal
948	Dyspepsia	31	0.3	0.3	no signal
949	Pollakiuria	13	0.3	0.3	no signal
950	Intraocular Pressure Increased	4	0.3	0.3	no signal
951	Therapeutic Response Unexpected	14	0.3	0.3	no signal
952	Incorrect Route Of Drug Administration	11	0.3	0.3	no signal
953	Contraindicated Product Administered	9	0.3	0.3	no signal
954	Ovarian Cyst	3	0.3	0.3	no signal
955	Type 2 Diabetes Mellitus	10	0.3	0.3	no signal
956	Tremor	49	0.3	0.3	no signal
957	Cerebrovascular Accident	50	0.3	0.3	no signal
958	Muscular Weakness	33	0.3	0.3	no signal
959	Emotional Disorder	9	0.3	0.3	no signal
960	Femur Fracture	9	0.3	0.3	no signal
961	Discomfort	17	0.3	0.3	no signal
962	Headache	175	0.3	0.3	no signal
963	Mobility Decreased	20	0.3	0.3	no signal
964	Rectal Haemorrhage	12	0.3	0.3	no signal
965	Eczema	14	0.3	0.3	no signal
966	Malaise	122	0.3	0.3	no signal
967	Heart Rate Increased	27	0.3	0.3	no signal
968	Fistula	3	0.3	0.3	no signal
969	Hypersensitivity	49	0.3	0.3	no signal
970	Aggression	13	0.3	0.3	no signal
971	Treatment Noncompliance	14	0.3	0.3	no signal
972	Fluid Retention	13	0.3	0.3	no signal
973	Hypoaesthesia	38	0.2	0.2	no signal
974	Swelling	23	0.2	0.2	no signal
975	Accidental Overdose	9	0.2	0.2	no signal
976	Prostate Cancer	19	0.2	0.2	no signal
977	Arthropathy	13	0.2	0.2	no signal
978	Migraine	22	0.2	0.2	no signal
979	Complication Associated With Device	3	0.2	0.2	no signal
980	Dizziness	112	0.2	0.2	no signal
981	Sinusitis	23	0.2	0.2	no signal
982	Synovitis	4	0.2	0.2	no signal
983	Rhinorrhoea	14	0.2	0.2	no signal
984	Amnesia	14	0.2	0.2	no signal
985	Myalgia	36	0.2	0.2	no signal
986	Memory Impairment	29	0.2	0.2	no signal
987	Hypoacusis	9	0.2	0.2	no signal
988	Diabetic Ketoacidosis	5	0.2	0.2	no signal
989	Gait Disturbance	40	0.2	0.2	no signal
990	Arthralgia	86	0.2	0.2	no signal
991	Mental Disorder	9	0.2	0.2	no signal
992	Plasma Cell Myeloma	8	0.2	0.2	no signal
993	Pruritus	76	0.2	0.2	no signal
994	Drug Hypersensitivity	39	0.2	0.2	no signal
995	Haematochezia	11	0.2	0.2	no signal
996	Irritability	12	0.2	0.2	no signal
997	Unevaluable Event	15	0.2	0.2	no signal
998	Gastric Cancer	5	0.2	0.2	no signal
999	Hyperhidrosis	25	0.2	0.2	no signal
1000	Dysphonia	11	0.2	0.2	no signal
1001	Depression	42	0.2	0.2	no signal
1002	Skin Exfoliation	15	0.2	0.2	no signal
1003	Metrorrhagia	3	0.2	0.2	no signal
1004	Overdose	37	0.2	0.2	no signal
1005	Blood Pressure Increased	26	0.2	0.2	no signal
1006	Lung Neoplasm Malignant	7	0.2	0.2	no signal
1007	Anxiety	48	0.2	0.2	no signal
1008	Rash Pruritic	9	0.2	0.2	no signal
1009	Myocardial Infarction	29	0.2	0.2	no signal
1010	Vertigo	10	0.2	0.2	no signal
1011	Blood Glucose Increased	31	0.2	0.2	no signal
1012	Peripheral Swelling	25	0.2	0.2	no signal
1013	Dysgeusia	12	0.2	0.2	no signal
1014	Abdominal Pain Upper	33	0.2	0.2	no signal
1015	Influenza	17	0.1	0.1	no signal
1016	Vision Blurred	20	0.1	0.1	no signal
1017	Visual Impairment	18	0.1	0.1	no signal
1018	Adverse Drug Reaction	12	0.1	0.1	no signal
1019	Flushing	13	0.1	0.1	no signal
1020	Fall	42	0.1	0.1	no signal
1021	Feeling Abnormal	30	0.1	0.1	no signal
1022	Bladder Cancer	7	0.1	0.1	no signal
1023	Weight Increased	26	0.1	0.1	no signal
1024	Device Delivery System Issue	3	0.1	0.1	no signal
1025	Abdominal Discomfort	19	0.1	0.1	no signal
1026	Gastrooesophageal Reflux Disease	9	0.1	0.1	no signal
1027	Palpitations	13	0.1	0.1	no signal
1028	Renal Cancer	5	0.1	0.1	no signal
1029	Muscle Spasms	19	0.1	0.1	no signal
1030	Urticaria	15	0.1	0.1	no signal
1031	Asthma	10	0.1	0.1	no signal
1032	Hospitalisation	13	0.1	0.1	no signal
1033	Dry Skin	10	0.1	0.1	no signal
1034	Nasopharyngitis	11	0.1	0.1	no signal
1035	Drug Dependence	9	0.1	0.1	no signal
1036	Inappropriate Schedule Of Product Administration	9	0.0	0.0	no signal
1037	Wrong Technique In Product Usage Process	10	0.0	0.0	no signal
1038	Insomnia	13	0.0	0.0	no signal