Reaction

Hostility reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,535 reports · 83 co-occurring drugs

As of the last recalculation, Hostility appears in 2,535 FAERS reports alongside 83 co-occurring drug terms. The strongest observed disproportionality signal is VARENICLINE TARTRATE (PRR 51.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Varenicline Tartrate	419	51.3	51.6
Botulinum Toxin Type A	41	27.5	27.6
Atomoxetine Hydrochloride	59	20.8	20.9
Lithium	62	20.7	20.7
Lithium Bromatum	62	20.7	20.7
Ziprasidone Mesylate	30	17.5	17.5
Ziprasidone	33	15.6	15.6
Guanfacine	14	14.7	14.7
Desvenlafaxine Succinate	47	14.5	14.6
Aripiprazole	196	14.2	14.2
Sumatriptan Succinate	42	13.9	13.9
Temazepam	57	12.7	12.7
Olanzapine Pamoate	58	11.9	11.9
Bupropion Hydrochloride	131	11.4	11.4
Paroxetine Hydrochloride	120	11.3	11.3
Felodipine Extended-Release Tablets	15	10.9	10.9
Felodipine	15	10.9	10.9
Lithium Carbonate	22	10.7	10.7
Aripiprazole Oral	52	10.5	10.5
Aripiprazole Orally Disintegrating	52	10.5	10.5
Asenapine Maleate	11	10.5	10.5
Venlafaxine Hydrochloride	154	10.1	10.1
Divalproex Sodium	55	9.9	9.9
Haloperidol	28	9.6	9.6
Haloperidol Lactate	28	9.4	9.4
Lisdexamfetamine Dimesylate	37	9.3	9.3
Bisacodyl Suppositories	14	8.9	8.9
Biscodyl	14	8.8	8.9
Cyclobenzaprine	52	8.7	8.7
Lamotirigine	72	8.5	8.5
Lamotrigine Extended-Release	72	8.5	8.5
Lamotrigine Chewable Dispersible	72	8.5	8.5
Bisacodyl	14	8.2	8.2
Fluoxetine Hydrochloride	122	8.2	8.2
Vilazodone Hydrochloride	9	8.0	8.0
Venlafaxine	68	8.0	8.0
Paroxetine Hydrochloride Hemihydrate	32	8.0	8.0
Paroxetine	32	7.8	7.8
Clonazepam	144	7.8	7.8
Olanzapine	97	7.7	7.7
Duloxetine Hydrochloride	163	7.5	7.5
Lamotrigine	115	7.5	7.5
Lurasidone Hydrochloride	18	7.1	7.1
Sumatriptan	32	7.0	7.0
Fluoxetine	55	6.9	6.9
Risperidone	107	6.9	6.9
Paliperidone Palmitate	26	6.7	6.7
Sertraline Hydrochloride	93	6.7	6.7
Topiramate	73	6.6	6.6
Paliperidone	18	6.4	6.4
Montelukast Sodium	91	6.3	6.3
Citalopram	99	6.1	6.1
Diazepam	85	5.9	5.9
Diazepam Oral Solution (Concentrate)	61	5.7	5.7
Diazepam Oral	61	5.7	5.7
Erenumab-Aooe	38	5.7	5.7
Citalopram Hydrobromide	73	5.7	5.7
Zonisamide	10	5.6	5.6
Quetiapine	124	5.5	5.5
Baclofen	56	5.4	5.4
Levetiracetam	85	5.4	5.4
Amphetamine	5	5.0	5.0
Ethyl Alcohol	16	4.9	4.9
Vortioxetine	10	4.8	4.8
Levetiracetam Injection	44	4.7	4.7
Brexpiprazole	9	4.5	4.5
Levetiracetam In Sodium Chloride	41	4.4	4.4
Levetiracetam Oral	41	4.4	4.4
Isopropyl Alcohol	18	4.4	4.4
Pimavanserin Tartrate	29	4.3	4.3
Lacosamide	19	4.2	4.2
Eszopiclone	13	4.2	4.2
Alcohol	19	4.0	4.0
Methylphenidate	14	4.0	4.0
Cenobamate	4	3.9	3.9
Brivaracetam	4	3.7	3.7
Cariprazine	4	3.5	3.5
Onabotulinumtoxina	30	3.2	3.2
Loratadine And Pseudoephedrine Sulfate	3	3.1	3.1
Derma Foam Excel Hand Sanitizer	3	3.1	3.1
Ethanol	3	3.1	3.1
Naltrexone Hydrochloride And Bupropion Hydrochloride	3	2.9	2.9
Esketamine Hydrochloride	5	2.3	2.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.