Drug

Aprepitant

1,102 flagged reaction(s) · 134,392 total co-reports · max PRR 2,091.9

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Computerised Tomogram Thorax	39	2,091.9	2,096.4	signal
2	Grip Strength	121	1,262.0	1,270.4	signal
3	Testicular Germ Cell Cancer Metastatic	13	1,046.0	1,046.7	signal
4	Swollen Joint Count	93	698.4	701.9	signal
5	Lupus Vulgaris	267	331.2	336.1	signal
6	Anti-cyclic Citrullinated Peptide Antibody	126	266.3	268.1	signal
7	Infusion Site Streaking	15	238.0	238.2	signal
8	Procalcitonin Decreased	12	237.1	237.3	signal
9	C-reactive Protein	147	221.1	222.9	signal
10	Acquired Porphyria	11	210.0	210.1	signal
11	Porphyria Acute	212	207.5	209.9	signal
12	Deep Vein Thrombosis Postoperative	296	203.3	206.6	signal
13	X-ray Abnormal	269	203.0	206.0	signal
14	Facet Joint Syndrome	432	181.6	185.9	signal
15	Pulmonary Septal Thickening	12	175.5	175.7	signal
16	Retinitis	221	174.4	176.6	signal
17	Adjustment Disorder With Depressed Mood	254	164.8	167.1	signal
18	Dislocation Of Vertebra	265	154.6	156.8	signal
19	Duodenal Ulcer Perforation	836	146.9	153.9	signal
20	Sleep Disorder Due To General Medical Condition, Insomnia Type	708	141.2	146.9	signal
21	Swollen Joint Count Increased	343	141.2	143.9	signal
22	Anti-cyclic Citrullinated Peptide Antibody Positive	718	128.4	133.6	signal
23	Computerised Tomogram Thorax Abnormal	66	119.5	120.0	signal
24	Rheumatic Fever	410	118.4	121.0	signal
25	Muscle Injury	769	118.1	123.3	signal
26	Nail Bed Inflammation	29	114.6	114.8	signal
27	Helicobacter Infection	860	105.3	110.4	signal
28	Folliculitis	870	105.1	110.3	signal
29	Rheumatoid Factor Positive	435	93.2	95.4	signal
30	Tonsillar Haemorrhage	11	91.8	91.8	signal
31	Intestinal Strangulation	12	90.7	90.8	signal
32	Bone Erosion	250	86.7	87.9	signal
33	C-reactive Protein Abnormal	431	82.4	84.3	signal
34	Eosinophil Percentage Decreased	13	81.8	81.9	signal
35	Hand Deformity	873	81.7	85.7	signal
36	Peripheral Venous Disease	263	80.5	81.7	signal
37	Intestinal Scarring	12	79.5	79.6	signal
38	Chemotherapeutic Drug Level Increased	10	70.4	70.4	signal
39	Subcutaneous Drug Absorption Impaired	31	68.9	69.0	signal
40	Pemphigus	701	68.3	70.9	signal
41	Seminoma	13	64.8	64.8	signal
42	Colony Stimulating Factor Therapy	11	63.9	63.9	signal
43	Drug Tolerance Decreased	136	58.3	58.7	signal
44	Nasal Mucosal Disorder	28	57.4	57.5	signal
45	Breast Cancer Stage Iii	302	56.2	57.2	signal
46	Lip Dry	402	53.6	54.8	signal
47	Synovitis	786	52.0	54.3	signal
48	Pericarditis	724	51.9	54.0	signal
49	Aplasia	86	51.4	51.6	signal
50	Blood Creatine Decreased	13	51.0	51.1	signal
51	Maternal Exposure Timing Unspecified	150	48.0	48.4	signal
52	Glossodynia	890	47.3	49.7	signal
53	Irritable Bowel Syndrome	793	44.0	46.0	signal
54	Acute Polyneuropathy	10	42.2	42.2	signal
55	Joint Range Of Motion Decreased	450	39.8	40.8	signal
56	Hypocholesterolaemia	10	38.3	38.3	signal
57	Bursitis	384	37.5	38.3	signal
58	Intercepted Drug Administration Error	14	37.1	37.1	signal
59	Autoimmune Disorder	284	34.9	35.4	signal
60	Herpes Simplex Reactivation	11	34.5	34.5	signal
61	Streptococcal Sepsis	35	34.5	34.6	signal
62	Wound Infection	313	33.9	34.4	signal
63	Febrile Bone Marrow Aplasia	115	32.2	32.4	signal
64	Wound	744	31.4	32.7	signal
65	Impaired Healing	868	31.0	32.5	signal
66	Vascular Pain	25	30.9	31.0	signal
67	Dental Fistula	11	30.8	30.8	signal
68	Sense Of Oppression	29	28.9	29.0	signal
69	Alveolitis	35	28.7	28.8	signal
70	Grip Strength Decreased	213	28.5	28.8	signal
71	Exostosis	222	28.5	28.8	signal
72	Coombs Positive Haemolytic Anaemia	11	27.7	27.7	signal
73	Systemic Lupus Erythematosus	817	27.0	28.2	signal
74	Infusion Site Vesicles	12	26.8	26.8	signal
75	Lupus-like Syndrome	207	26.8	27.1	signal
76	Sciatica	361	26.6	27.1	signal
77	Hypercholesterolaemia	214	26.1	26.4	signal
78	Neutropenic Colitis	46	26.1	26.1	signal
79	Seronegative Arthritis	25	26.0	26.0	signal
80	Aortic Valve Calcification	11	25.0	25.0	signal
81	Pseudomonal Sepsis	36	23.8	23.9	signal
82	Hemianopia	20	23.3	23.3	signal
83	Fibromyalgia	485	23.3	23.9	signal
84	Laryngitis	212	22.7	23.0	signal
85	Change Of Bowel Habit	40	22.7	22.8	signal
86	Aortitis	13	22.2	22.2	signal
87	Walking Aid User	124	21.8	21.9	signal
88	Hypermagnesaemia	12	21.8	21.8	signal
89	Periorbital Cellulitis	10	21.7	21.8	signal
90	C-reactive Protein Decreased	12	21.4	21.4	signal
91	Lower Respiratory Tract Infection	821	21.1	22.0	signal
92	Contraindicated Product Administered	545	21.0	21.6	signal
93	Obesity	288	21.0	21.3	signal
94	Live Birth	150	20.9	21.1	signal
95	Blood Folate Decreased	13	20.9	20.9	signal
96	Lower Limb Fracture	340	20.7	21.1	signal
97	Klebsiella Bacteraemia	16	20.0	20.0	signal
98	Abdominal Sepsis	15	19.9	19.9	signal
99	Stoma Site Pain	25	19.8	19.9	signal
100	Stomatitis	1,035	19.8	20.9	signal
101	Febrile Neutropenia	1,076	18.9	20.0	signal
102	Hiccups	131	18.6	18.8	signal
103	Infusion Related Reaction	1,040	18.3	19.3	signal
104	Laryngeal Discomfort	10	18.2	18.2	signal
105	Foot Deformity	174	18.2	18.3	signal
106	Pulmonary Fibrosis	298	18.1	18.4	signal
107	Ulcer Haemorrhage	105	18.0	18.1	signal
108	Sputum Abnormal	10	17.7	17.7	signal
109	Atelectasis	148	17.7	17.8	signal
110	Tonic Clonic Movements	19	17.0	17.0	signal
111	Prescribed Overdose	281	16.8	17.1	signal
112	Tumour Pain	19	16.6	16.6	signal
113	Drug Clearance Decreased	18	16.6	16.6	signal
114	Cystitis Haemorrhagic	57	16.4	16.5	signal
115	Nail Infection	20	16.2	16.2	signal
116	Streptococcal Bacteraemia	15	16.2	16.2	signal
117	Vascular Device Infection	63	16.2	16.2	signal
118	Catheter Site Related Reaction	10	16.1	16.1	signal
119	Blister	776	16.0	16.7	signal
120	Red Blood Cell Sedimentation Rate Increased	153	16.0	16.1	signal
121	Hypochloraemia	16	15.9	15.9	signal
122	Type 2 Diabetes Mellitus	444	15.2	15.6	signal
123	Arthropathy	724	15.0	15.6	signal
124	Hepatic Enzyme Increased	870	14.8	15.5	signal
125	Superinfection Bacterial	10	14.6	14.6	signal
126	Facial Asymmetry	12	14.6	14.6	signal
127	Ill-defined Disorder	765	14.5	15.1	signal
128	Liver Injury	302	14.4	14.7	signal
129	Subacute Cutaneous Lupus Erythematosus	22	14.4	14.4	signal
130	Immune-mediated Hypothyroidism	13	14.0	14.0	signal
131	Discomfort	732	14.0	14.5	signal
132	Hepatic Cirrhosis	221	13.7	13.8	signal
133	Fixed Eruption	20	13.6	13.7	signal
134	Palmar Erythema	13	13.1	13.1	signal
135	Night Sweats	362	13.0	13.2	signal
136	Mucosal Inflammation	293	13.0	13.2	signal
137	Blood Urea Decreased	14	12.9	12.9	signal
138	Hair Disorder	93	12.9	12.9	signal
139	Hyperammonaemic Encephalopathy	19	12.8	12.8	signal
140	Therapeutic Product Effect Decreased	491	12.8	13.1	signal
141	Liver Disorder	489	12.7	13.1	signal
142	Pregnancy	222	12.7	12.8	signal
143	Thrombocytopenic Purpura	15	12.5	12.5	signal
144	Prescribed Underdose	214	12.4	12.5	signal
145	Hepatocellular Injury	151	12.3	12.3	signal
146	Subileus	22	12.1	12.1	signal
147	Intestinal Ischaemia	57	12.0	12.0	signal
148	Paronychia	45	12.0	12.0	signal
149	Eosinophil Count Decreased	24	11.9	11.9	signal
150	Eye Injury	31	11.9	11.9	signal
151	Psychological Trauma	90	11.9	11.9	signal
152	Psoriatic Arthropathy	410	11.8	12.0	signal
153	Sleep Disorder	711	11.7	12.2	signal
154	Toxic Encephalopathy	50	11.7	11.7	signal
155	Gastrointestinal Disorder	890	11.6	12.2	signal
156	Candida Sepsis	9	11.5	11.5	signal
157	Onychalgia	10	11.5	11.5	signal
158	Cerebellar Syndrome	22	11.5	11.5	signal
159	Joint Dislocation	104	11.4	11.4	signal
160	Alopecia Areata	17	11.2	11.2	signal
161	Carbon Dioxide Decreased	11	11.1	11.1	signal
162	Vena Cava Thrombosis	16	11.1	11.1	signal
163	Road Traffic Accident	399	11.0	11.2	signal
164	Radiation Skin Injury	11	10.9	10.9	signal
165	Aortic Thrombosis	11	10.9	10.9	signal
166	Abdominal Operation	12	10.8	10.8	signal
167	Frequent Bowel Movements	252	10.8	10.9	signal
168	Immune-mediated Enterocolitis	33	10.8	10.8	signal
169	Secondary Adrenocortical Insufficiency	14	10.8	10.8	signal
170	Left Atrial Dilatation	12	10.8	10.8	signal
171	Injury	658	10.7	11.1	signal
172	Weight Fluctuation	97	10.7	10.8	signal
173	Capillary Leak Syndrome	19	10.7	10.7	signal
174	Blood Chloride Decreased	24	10.6	10.6	signal
175	Body Temperature Abnormal	17	10.6	10.6	signal
176	Encephalopathy	220	10.3	10.5	signal
177	Delirium	308	10.3	10.4	signal
178	Hair Colour Changes	112	10.3	10.3	signal
179	Inappropriate Antidiuretic Hormone Secretion	90	10.2	10.2	signal
180	Death Neonatal	12	10.0	10.0	signal
181	Swelling	810	10.0	10.4	signal
182	Enteritis	55	10.0	10.0	signal
183	Neutrophil Count Decreased	350	9.9	10.1	signal
184	Oesophagitis	94	9.9	9.9	signal
185	Hip Arthroplasty	130	9.9	9.9	signal
186	Madarosis	100	9.8	9.9	signal
187	Hepatic Cytolysis	104	9.8	9.8	signal
188	Wheezing	502	9.8	10.0	signal
189	Pustular Psoriasis	29	9.7	9.7	signal
190	Lung Disorder	410	9.6	9.8	signal
191	Pharyngeal Erythema	18	9.6	9.6	signal
192	Sleep Disorder Due To A General Medical Condition	134	9.5	9.6	signal
193	Bicytopenia	16	9.5	9.5	signal
194	Hair Texture Abnormal	111	9.5	9.5	signal
195	Contusion	787	9.4	9.8	signal
196	Sinusitis	829	9.3	9.7	signal
197	Eastern Cooperative Oncology Group Performance Status Worsened	10	9.3	9.3	signal
198	Blood Cholesterol Increased	374	9.2	9.4	signal
199	Bone Marrow Failure	164	9.2	9.3	signal
200	Cytolytic Hepatitis	27	9.2	9.2	signal
201	Inflammation	405	9.1	9.3	signal
202	General Physical Health Deterioration	905	9.1	9.5	signal
203	Ear Infection	209	9.1	9.2	signal
204	Peripheral Sensory Neuropathy	46	9.1	9.1	signal
205	Medication Error	428	8.9	9.1	signal
206	Post Herpetic Neuralgia	11	8.8	8.8	signal
207	Atrioventricular Block Second Degree	23	8.7	8.7	signal
208	Large Intestine Perforation	52	8.6	8.6	signal
209	Anorectal Disorder	15	8.6	8.6	signal
210	Aplastic Anaemia	39	8.6	8.6	signal
211	C-reactive Protein Increased	269	8.5	8.6	signal
212	Tongue Ulceration	25	8.5	8.5	signal
213	Gait Inability	244	8.5	8.6	signal
214	Hyperthermia	55	8.4	8.4	signal
215	Musculoskeletal Pain	383	8.3	8.5	signal
216	Infusion Site Reaction	21	8.3	8.3	signal
217	Diabetic Metabolic Decompensation	10	8.3	8.3	signal
218	Electrocardiogram T Wave Inversion	16	8.3	8.3	signal
219	Oedema	389	8.3	8.4	signal
220	Enterocolitis	41	8.3	8.3	signal
221	Rash Maculo-papular	158	8.2	8.3	signal
222	Tonic Convulsion	10	8.2	8.2	signal
223	Neutropenic Sepsis	51	8.2	8.2	signal
224	Staphylococcus Test Positive	15	8.1	8.1	signal
225	Therapy Non-responder	314	8.1	8.2	signal
226	Osteoarthritis	297	8.0	8.2	signal
227	Tongue Coated	12	8.0	8.0	signal
228	Hypomagnesaemia	96	8.0	8.0	signal
229	Ear Pain	134	7.9	8.0	signal
230	Anaphylactoid Reaction	28	7.9	7.9	signal
231	Hypophosphataemia	50	7.8	7.8	signal
232	Jugular Vein Thrombosis	12	7.8	7.8	signal
233	Blepharospasm	42	7.8	7.8	signal
234	Rheumatoid Arthritis	763	7.8	8.0	signal
235	Alopecia	1,327	7.8	8.3	signal
236	Joint Swelling	808	7.7	8.0	signal
237	Soft Tissue Infection	12	7.6	7.6	signal
238	Infection	938	7.5	7.8	signal
239	Ototoxicity	12	7.4	7.4	signal
240	Hypokalaemia	296	7.4	7.5	signal
241	Phlebitis	33	7.4	7.4	signal
242	Regurgitation	22	7.4	7.4	signal
243	Hypersensitivity	1,182	7.3	7.8	signal
244	Spondylitis	23	7.3	7.3	signal
245	Splenic Infarction	11	7.3	7.3	signal
246	Keratitis	19	7.2	7.2	signal
247	Non-cardiac Chest Pain	20	7.2	7.2	signal
248	Rash Vesicular	30	7.2	7.2	signal
249	Gastrointestinal Necrosis	18	7.1	7.1	signal
250	Oral Pain	139	7.1	7.2	signal
251	Drug Intolerance	593	7.1	7.3	signal
252	Rectal Haemorrhage	265	7.1	7.1	signal
253	Dermatitis Acneiform	37	7.0	7.0	signal
254	Nail Disorder	53	7.0	7.0	signal
255	Fluid Intake Reduced	30	7.0	7.0	signal
256	Breast Cancer Stage Ii	51	7.0	7.0	signal
257	Mobility Decreased	431	6.9	7.1	signal
258	Red Cell Distribution Width Increased	25	6.9	6.9	signal
259	Varicose Vein	31	6.9	6.9	signal
260	Metastases To Lymph Nodes	40	6.8	6.9	signal
261	Abdominal Rigidity	16	6.8	6.8	signal
262	Confusional State	957	6.8	7.1	signal
263	Erosive Oesophagitis	10	6.7	6.7	signal
264	Left Ventricular Dysfunction	39	6.7	6.7	signal
265	Feeling Hot	358	6.7	6.8	signal
266	Arteriospasm Coronary	23	6.7	6.7	signal
267	Knee Arthroplasty	121	6.7	6.7	signal
268	Hypoxia	203	6.6	6.7	signal
269	Immune-mediated Hepatic Disorder	11	6.6	6.6	signal
270	Tumour Lysis Syndrome	50	6.6	6.6	signal
271	Thrombocytopenia	634	6.5	6.7	signal
272	Hyponatraemia	319	6.5	6.6	signal
273	Chemotherapy	21	6.5	6.5	signal
274	Thrombophlebitis	20	6.5	6.5	signal
275	Gastrointestinal Perforation	23	6.4	6.4	signal
276	White Blood Cell Count Increased	213	6.3	6.4	signal
277	Maternal Exposure During Pregnancy	486	6.3	6.5	signal
278	Clonus	15	6.3	6.3	signal
279	Toxic Skin Eruption	55	6.2	6.3	signal
280	Dry Mouth	439	6.2	6.3	signal
281	Joint Stiffness	142	6.2	6.3	signal
282	Hyperammonaemia	27	6.2	6.2	signal
283	Interstitial Lung Disease	260	6.2	6.3	signal
284	Cholangitis	33	6.1	6.2	signal
285	Anaphylactic Shock	137	6.1	6.2	signal
286	Protein Total Decreased	20	6.1	6.1	signal
287	Cardiotoxicity	47	6.1	6.1	signal
288	Blood Culture Positive	16	6.1	6.1	signal
289	Venous Thrombosis Limb	11	6.0	6.0	signal
290	Colitis Ulcerative	234	6.0	6.1	signal
291	Female Genital Tract Fistula	9	6.0	6.0	signal
292	Vitamin B12 Deficiency	21	6.0	6.0	signal
293	Lung Cancer Metastatic	15	6.0	6.0	signal
294	Osteoporosis	214	6.0	6.0	signal
295	Toxic Epidermal Necrolysis	78	5.9	6.0	signal
296	Immune-mediated Lung Disease	9	5.9	5.9	signal
297	Gastric Perforation	14	5.9	5.9	signal
298	Neutropenia	694	5.9	6.1	signal
299	Treatment Failure	419	5.9	6.0	signal
300	Immune-mediated Hepatitis	10	5.8	5.8	signal
301	Laboratory Test Abnormal	150	5.8	5.9	signal
302	Ileus	62	5.8	5.8	signal
303	Hypernatraemia	25	5.8	5.8	signal
304	Disseminated Intravascular Coagulation	71	5.8	5.8	signal
305	Incorrect Route Of Product Administration	83	5.7	5.7	signal
306	Cerebral Venous Thrombosis	9	5.7	5.7	signal
307	Immune Thrombocytopenia	22	5.6	5.6	signal
308	Leukopenia	245	5.6	5.7	signal
309	Odynophagia	29	5.6	5.6	signal
310	Generalised Erythema	28	5.6	5.6	signal
311	Abdominal Discomfort	807	5.5	5.7	signal
312	Pancytopenia	268	5.5	5.6	signal
313	Mixed Liver Injury	14	5.5	5.5	signal
314	Peripheral Swelling	736	5.5	5.7	signal
315	Venoocclusive Disease	12	5.5	5.5	signal
316	Pyrexia	1,653	5.5	5.9	signal
317	Respiratory Syncytial Virus Infection	41	5.4	5.4	signal
318	Decreased Appetite	1,096	5.4	5.7	signal
319	Pancreatitis	250	5.4	5.5	signal
320	Cholestasis	90	5.4	5.4	signal
321	Myositis	42	5.4	5.4	signal
322	Musculoskeletal Stiffness	410	5.4	5.5	signal
323	Blood Phosphorus Decreased	17	5.4	5.4	signal
324	Radiation Pneumonitis	10	5.3	5.4	signal
325	Mouth Ulceration	98	5.3	5.4	signal
326	Intentional Product Use Issue	408	5.3	5.4	signal
327	Neuropathy Peripheral	437	5.3	5.4	signal
328	Pulse Absent	22	5.3	5.3	signal
329	Metastases To Central Nervous System	59	5.3	5.3	signal
330	Drug-induced Liver Injury	142	5.3	5.3	signal
331	Renal Tubular Disorder	13	5.3	5.3	signal
332	Extravasation	19	5.3	5.3	signal
333	Oropharyngeal Discomfort	41	5.3	5.3	signal
334	Nasopharyngitis	847	5.3	5.5	signal
335	Septic Shock	198	5.3	5.3	signal
336	Respiratory Disorder	137	5.2	5.3	signal
337	Pancreatitis Acute	100	5.1	5.2	signal
338	Adenocarcinoma	10	5.1	5.1	signal
339	Pulmonary Toxicity	31	5.1	5.1	signal
340	Urinary Tract Infection Bacterial	11	5.0	5.0	signal
341	Palmar-plantar Erythrodysaesthesia Syndrome	102	5.0	5.0	signal
342	Hepatitis Cholestatic	26	5.0	5.0	signal
343	Rash Morbilliform	12	5.0	5.0	signal
344	Hypoalbuminaemia	33	4.9	5.0	signal
345	Incorrect Drug Administration Rate	18	4.9	4.9	signal
346	Neutrophil Count Abnormal	12	4.9	4.9	signal
347	Meningitis Aseptic	19	4.9	4.9	signal
348	Poor Peripheral Circulation	18	4.8	4.8	signal
349	Anaphylactic Reaction	230	4.8	4.8	signal
350	Tongue Oedema	16	4.8	4.8	signal
351	Amnesia	273	4.8	4.8	signal
352	Blood Albumin Decreased	33	4.8	4.8	signal
353	Infusion Site Pruritus	13	4.8	4.8	signal
354	Peripheral Ischaemia	17	4.8	4.8	signal
355	Supraventricular Extrasystoles	14	4.7	4.8	signal
356	Intracranial Pressure Increased	23	4.7	4.7	signal
357	Body Temperature Increased	84	4.7	4.7	signal
358	Pneumocystis Jirovecii Pneumonia	41	4.7	4.7	signal
359	Infusion Site Erythema	34	4.7	4.7	signal
360	Onychomadesis	17	4.7	4.7	signal
361	Oedema Peripheral	500	4.7	4.8	signal
362	Stridor	12	4.7	4.7	signal
363	Embolism	34	4.7	4.7	signal
364	Venoocclusive Liver Disease	20	4.7	4.7	signal
365	Blood Magnesium Decreased	35	4.6	4.7	signal
366	Type Iv Hypersensitivity Reaction	11	4.6	4.6	signal
367	Aortic Stenosis	14	4.6	4.6	signal
368	Gamma-glutamyltransferase Increased	89	4.6	4.6	signal
369	Type I Hypersensitivity	14	4.6	4.6	signal
370	Deafness Neurosensory	13	4.5	4.5	signal
371	Muscle Spasticity	49	4.5	4.5	signal
372	Catheter Site Pain	10	4.5	4.5	signal
373	Cancer Pain	10	4.5	4.5	signal
374	Dermatitis Bullous	28	4.5	4.5	signal
375	Pancreatic Carcinoma Metastatic	11	4.4	4.4	signal
376	Agranulocytosis	71	4.4	4.4	signal
377	Ileus Paralytic	17	4.4	4.4	signal
378	Colitis	144	4.4	4.4	signal
379	Lipase Increased	29	4.4	4.4	signal
380	Aphthous Ulcer	29	4.3	4.3	signal
381	Infusion Site Pain	48	4.3	4.3	signal
382	Lumbar Vertebral Fracture	17	4.3	4.3	signal
383	Electrolyte Imbalance	43	4.3	4.3	signal
384	Acute Pulmonary Oedema	21	4.3	4.3	signal
385	Spinal Fusion Surgery	15	4.3	4.3	signal
386	Weight Increased	822	4.2	4.4	signal
387	Hyperbilirubinaemia	38	4.2	4.2	signal
388	Jaundice Cholestatic	13	4.2	4.2	signal
389	Hypertransaminasaemia	25	4.2	4.2	signal
390	Epilepsy	111	4.2	4.2	signal
391	Abdominal Tenderness	18	4.2	4.2	signal
392	Cytokine Release Syndrome	69	4.1	4.2	signal
393	Polyneuropathy	43	4.1	4.1	signal
394	Gastrointestinal Tube Insertion	9	4.1	4.1	signal
395	Lung Infiltration	32	4.1	4.1	signal
396	Disability	71	4.1	4.1	signal
397	Gastrointestinal Motility Disorder	19	4.1	4.1	signal
398	Adverse Event	329	4.1	4.1	signal
399	Brain Oedema	45	4.1	4.1	signal
400	Hypoaesthesia	531	4.1	4.2	signal
401	Cerebral Thrombosis	10	4.0	4.1	signal
402	Dermatitis Exfoliative Generalised	12	4.0	4.0	signal
403	Staphylococcal Bacteraemia	15	4.0	4.0	signal
404	Bronchospasm	49	3.9	3.9	signal
405	Hypovolaemia	20	3.9	3.9	signal
406	Exposure During Pregnancy	212	3.9	3.9	signal
407	Gastrointestinal Toxicity	16	3.9	3.9	signal
408	Thoracic Vertebral Fracture	10	3.9	3.9	signal
409	Oral Candidiasis	44	3.9	3.9	signal
410	Infusion Site Extravasation	21	3.9	3.9	signal
411	Acute Generalised Exanthematous Pustulosis	26	3.8	3.9	signal
412	Hypertension	711	3.8	4.0	signal
413	Hypoventilation	11	3.8	3.8	signal
414	White Blood Cell Count Decreased	363	3.8	3.9	signal
415	Hypocalcaemia	63	3.8	3.8	signal
416	Urticaria	554	3.8	3.9	signal
417	Erythema Multiforme	31	3.8	3.8	signal
418	Flank Pain	31	3.8	3.8	signal
419	Dysaesthesia	10	3.8	3.8	signal
420	Device Related Infection	51	3.8	3.8	signal
421	Candida Infection	55	3.8	3.8	signal
422	Blood Alkaline Phosphatase Increased	82	3.8	3.8	signal
423	Embolism Venous	10	3.8	3.8	signal
424	Vomiting	1,542	3.8	4.0	signal
425	Sputum Discoloured	31	3.8	3.8	signal
426	Dyspepsia	320	3.7	3.8	signal
427	Duodenitis	10	3.7	3.7	signal
428	Organising Pneumonia	16	3.7	3.7	signal
429	Paraesthesia	513	3.7	3.8	signal
430	Endotracheal Intubation	9	3.7	3.7	signal
431	Aplasia Pure Red Cell	11	3.7	3.7	signal
432	Tachycardia	284	3.7	3.7	signal
433	Chest Pain	591	3.6	3.7	signal
434	Faeces Soft	23	3.6	3.6	signal
435	Hyperuricaemia	13	3.6	3.6	signal
436	Systemic Inflammatory Response Syndrome	12	3.6	3.6	signal
437	Platelet Count Increased	41	3.6	3.6	signal
438	Insomnia	836	3.6	3.7	signal
439	Skin Fissures	59	3.6	3.6	signal
440	Escherichia Sepsis	9	3.6	3.6	signal
441	Adrenal Insufficiency	37	3.5	3.5	signal
442	Fibrin D Dimer Increased	11	3.5	3.5	signal
443	Hallucinations, Mixed	13	3.5	3.5	signal
444	Vulvovaginal Mycotic Infection	12	3.5	3.5	signal
445	Platelet Count Decreased	325	3.5	3.5	signal
446	General Symptom	23	3.5	3.5	signal
447	Iron Deficiency Anaemia	28	3.5	3.5	signal
448	Taste Disorder	61	3.5	3.5	signal
449	Polydipsia	12	3.5	3.5	signal
450	Feeding Disorder	60	3.4	3.5	signal
451	Hypercapnia	9	3.4	3.4	signal
452	Colitis Ischaemic	20	3.4	3.4	signal
453	Aspiration	32	3.4	3.4	signal
454	Drug Tolerance	15	3.4	3.4	signal
455	Renal Failure Acute	127	3.4	3.4	signal
456	Transfusion	31	3.4	3.4	signal
457	Rash	1,269	3.4	3.5	signal
458	Hepatic Function Abnormal	108	3.3	3.3	signal
459	Haemolytic Anaemia	26	3.3	3.3	signal
460	Bacteraemia	34	3.3	3.3	signal
461	Asthma	323	3.3	3.3	signal
462	Eosinophilic Pneumonia	9	3.3	3.3	signal
463	Skin Toxicity	16	3.3	3.3	signal
464	Blood Urea Increased	48	3.3	3.3	signal
465	Pruritus	1,076	3.3	3.4	signal
466	Nausea	2,245	3.3	3.6	signal
467	Abdominal Pain	658	3.2	3.3	signal
468	Muscle Contractions Involuntary	10	3.2	3.2	signal
469	Pneumonitis	76	3.2	3.2	signal
470	Dyspnoea	1,583	3.2	3.4	signal
471	Flushing	284	3.2	3.2	signal
472	Hepatitis	71	3.2	3.2	signal
473	Vein Disorder	14	3.2	3.2	signal
474	Skin Reaction	39	3.2	3.2	signal
475	Laryngeal Oedema	17	3.2	3.2	signal
476	Ejection Fraction Decreased	43	3.2	3.2	signal
477	Drug Interaction	438	3.2	3.2	signal
478	Hypophagia	70	3.2	3.2	signal
479	Bacterial Sepsis	9	3.2	3.2	signal
480	Hypertriglyceridaemia	16	3.1	3.1	signal
481	Oxygen Saturation Decreased	153	3.1	3.2	signal
482	Thrombocytosis	10	3.1	3.1	signal
483	Muscular Weakness	311	3.1	3.2	signal
484	Mouth Haemorrhage	20	3.1	3.1	signal
485	Supraventricular Tachycardia	26	3.1	3.1	signal
486	Haemolysis	21	3.1	3.1	signal
487	Impaired Quality Of Life	39	3.1	3.1	signal
488	Trismus	14	3.1	3.1	signal
489	Lymphopenia	38	3.1	3.1	signal
490	Drug Hypersensitivity	520	3.1	3.1	signal
491	Retinopathy	10	3.1	3.1	signal
492	Acute Kidney Injury	407	3.1	3.1	signal
493	Jaundice	72	3.1	3.1	signal
494	Renal Tubular Necrosis	26	3.0	3.0	signal
495	Abdominal Pain Upper	538	3.0	3.1	signal
496	Dehydration	348	3.0	3.0	signal
497	Small For Dates Baby	13	3.0	3.0	signal
498	Deep Vein Thrombosis	170	3.0	3.0	signal
499	Constipation	562	3.0	3.0	signal
500	Rosacea	12	3.0	3.0	signal
501	Anaemia	493	3.0	3.0	signal
502	Intestinal Perforation	29	3.0	3.0	signal
503	Hyperreflexia	9	2.9	2.9	signal
504	Generalised Tonic-clonic Seizure	42	2.9	2.9	signal
505	Hypothermia	26	2.9	2.9	signal
506	Anuria	22	2.9	2.9	signal
507	Non-small Cell Lung Cancer	12	2.9	2.9	signal
508	Oesophageal Candidiasis	10	2.9	2.9	signal
509	Pleural Effusion	154	2.9	2.9	signal
510	Pneumothorax	40	2.9	2.9	signal
511	Sinus Headache	15	2.9	2.9	signal
512	Fatigue	1,943	2.9	3.1	signal
513	Pulmonary Alveolar Haemorrhage	14	2.9	2.9	signal
514	Diarrhoea	1,603	2.9	3.0	signal
515	Proctalgia	16	2.9	2.9	signal
516	Erythema	509	2.8	2.9	signal
517	Recurrent Cancer	10	2.8	2.8	signal
518	Infusion Site Swelling	15	2.8	2.8	signal
519	Sudden Death	26	2.8	2.8	signal
520	Condition Aggravated	732	2.8	2.8	signal
521	Asthenia	908	2.8	2.9	signal
522	Klebsiella Infection	12	2.7	2.7	signal
523	Epistaxis	179	2.7	2.7	signal
524	Drug Eruption	42	2.7	2.7	signal
525	Product Use Issue	445	2.7	2.8	signal
526	Lymphocyte Count Decreased	42	2.7	2.7	signal
527	Dermatitis Exfoliative	12	2.7	2.7	signal
528	Blood Bilirubin Increased	64	2.7	2.7	signal
529	Cachexia	12	2.7	2.7	signal
530	Muscle Spasms	430	2.7	2.7	signal
531	Transaminases Increased	52	2.7	2.7	signal
532	Circulatory Collapse	40	2.7	2.7	signal
533	Loss Of Personal Independence In Daily Activities	111	2.7	2.7	signal
534	Memory Impairment	320	2.7	2.7	signal
535	Migraine	220	2.7	2.7	signal
536	Peritonitis	48	2.7	2.7	signal
537	Tearfulness	10	2.6	2.6	signal
538	Spinal Pain	27	2.6	2.6	signal
539	Cholecystitis Acute	13	2.6	2.6	signal
540	Aspartate Aminotransferase Increased	122	2.6	2.6	signal
541	Upper Respiratory Tract Infection	106	2.6	2.6	signal
542	Blepharitis	9	2.6	2.6	signal
543	Arthritis	179	2.6	2.6	signal
544	Haemodynamic Instability	17	2.6	2.6	signal
545	Ascites	66	2.6	2.6	signal
546	Rash Pruritic	121	2.6	2.6	signal
547	Haemorrhoidal Haemorrhage	11	2.6	2.6	signal
548	Breath Sounds Abnormal	11	2.6	2.6	signal
549	Cardio-respiratory Arrest	93	2.5	2.5	signal
550	Papilloedema	10	2.5	2.5	signal
551	Sepsis	246	2.5	2.5	signal
552	Neurotoxicity	38	2.5	2.5	signal
553	Cytopenia	26	2.5	2.5	signal
554	Malnutrition	24	2.5	2.5	signal
555	Pulmonary Embolism	206	2.5	2.5	signal
556	Liver Function Test Increased	46	2.5	2.5	signal
557	Streptococcal Infection	12	2.5	2.5	signal
558	Arthralgia	892	2.5	2.5	signal
559	Underdose	157	2.5	2.5	signal
560	Myocarditis	24	2.4	2.4	signal
561	Subcutaneous Abscess	10	2.4	2.4	signal
562	Alanine Aminotransferase Increased	128	2.4	2.4	signal
563	Escherichia Infection	17	2.4	2.4	signal
564	Clostridium Difficile Colitis	22	2.4	2.4	signal
565	Product Label Confusion	12	2.4	2.4	signal
566	Weight Decreased	574	2.4	2.4	signal
567	Pneumonia	664	2.3	2.4	signal
568	Metabolic Acidosis	65	2.3	2.4	signal
569	Small Intestinal Obstruction	25	2.3	2.3	signal
570	Purpura	18	2.3	2.3	signal
571	Acute Respiratory Distress Syndrome	36	2.3	2.3	signal
572	Lymphoedema	14	2.3	2.3	signal
573	Malaise	890	2.3	2.4	signal
574	Normal Newborn	11	2.3	2.3	signal
575	Paraesthesia Oral	29	2.3	2.3	signal
576	Chest Discomfort	205	2.3	2.3	signal
577	Hydronephrosis	15	2.3	2.3	signal
578	Cerebral Infarction	49	2.3	2.3	signal
579	Metastases To Liver	35	2.3	2.3	signal
580	Altered State Of Consciousness	43	2.3	2.3	signal
581	Respiratory Distress	55	2.3	2.3	signal
582	Vaginal Discharge	20	2.3	2.3	signal
583	Erysipelas	10	2.3	2.3	signal
584	Myelosuppression	67	2.3	2.3	signal
585	Petit Mal Epilepsy	10	2.2	2.2	signal
586	Malignant Neoplasm Progression	200	2.2	2.3	signal
587	Ischaemic Stroke	35	2.2	2.2	signal
588	Immune Effector Cell-associated Neurotoxicity Syndrome	11	2.2	2.2	signal
589	Cardiac Failure Acute	13	2.2	2.2	signal
590	Ear Discomfort	20	2.2	2.2	signal
591	Hypotension	391	2.2	2.3	signal
592	Dysgeusia	145	2.2	2.2	signal
593	Urine Output Decreased	17	2.2	2.2	signal
594	Restlessness	71	2.2	2.2	signal
595	Oliguria	12	2.2	2.2	signal
596	Product Use In Unapproved Indication	471	2.2	2.2	signal
597	Chills	226	2.2	2.2	signal
598	Tonsillitis	10	2.2	2.2	signal
599	Failure To Thrive	10	2.2	2.2	signal
600	Blood Sodium Decreased	36	2.2	2.2	signal
601	Atrial Fibrillation	186	2.2	2.2	signal
602	Oral Disorder	14	2.2	2.2	signal
603	Sinus Tachycardia	27	2.2	2.2	signal
604	Polyarthritis	10	2.2	2.2	signal
605	Haematocrit Decreased	38	2.2	2.2	signal
606	Disease Progression	224	2.2	2.2	signal
607	Red Blood Cell Count Decreased	54	2.2	2.2	signal
608	Acute Respiratory Failure	36	2.2	2.2	signal
609	Feeling Of Body Temperature Change	11	2.1	2.1	signal
610	Hyperthyroidism	27	2.1	2.1	signal
611	Guillain-barre Syndrome	9	2.1	2.1	signal
612	Proteinuria	35	2.1	2.1	signal
613	Visual Impairment	227	2.1	2.1	signal
614	Aphagia	9	2.1	2.1	signal
615	Hydrocephalus	10	2.1	2.1	signal
616	Face Oedema	31	2.1	2.1	signal
617	Hyperglycaemia	66	2.1	2.1	signal
618	Intestinal Obstruction	68	2.1	2.1	signal
619	Neuralgia	44	2.1	2.1	signal
620	Adverse Drug Reaction	162	2.1	2.1	signal
621	Haematemesis	46	2.1	2.1	signal
622	Lacrimation Increased	54	2.1	2.1	signal
623	Congenital Anomaly	14	2.1	2.1	signal
624	Eyelid Oedema	21	2.1	2.1	signal
625	Unresponsive To Stimuli	46	2.0	2.0	signal
626	Multi-organ Failure	31	2.0	2.0	signal
627	Blood Lactate Dehydrogenase Increased	28	2.0	2.0	signal
628	Back Injury	19	2.0	2.0	signal
629	Sunburn	13	2.0	2.0	no signal
630	Myocardial Ischaemia	20	2.0	2.0	no signal
631	Conjunctivitis	32	2.0	2.0	no signal
632	Petechiae	18	2.0	2.0	no signal
633	Mental Status Changes	48	2.0	2.0	no signal
634	Aphasia	52	2.0	2.0	no signal
635	Gastroenteritis	25	2.0	2.0	no signal
636	Cyanosis	27	2.0	2.0	no signal
637	Blood Creatinine Increased	112	2.0	2.0	no signal
638	Generalised Oedema	21	1.9	2.0	no signal
639	Back Pain	396	1.9	2.0	no signal
640	Duodenal Ulcer	12	1.9	1.9	no signal
641	Tachypnoea	23	1.9	1.9	no signal
642	Pharyngitis	21	1.9	1.9	no signal
643	Pain	1,029	1.9	2.0	no signal
644	Haematuria	57	1.9	1.9	no signal
645	Pain In Extremity	488	1.9	1.9	no signal
646	Sinus Bradycardia	16	1.9	1.9	no signal
647	Thrombotic Microangiopathy	16	1.9	1.9	no signal
648	Metastases To Bone	27	1.9	1.9	no signal
649	Pneumonia Bacterial	15	1.9	1.9	no signal
650	Off Label Use	1,423	1.9	1.9	no signal
651	Haemoglobin Decreased	168	1.9	1.9	no signal
652	Gingival Pain	13	1.9	1.9	no signal
653	Respiratory Depression	20	1.9	1.9	no signal
654	Eructation	31	1.9	1.9	no signal
655	Tenderness	17	1.9	1.9	no signal
656	Dysphagia	154	1.9	1.9	no signal
657	Rhinitis	13	1.8	1.8	no signal
658	Ketoacidosis	12	1.8	1.8	no signal
659	Incontinence	17	1.8	1.8	no signal
660	Fistula	18	1.8	1.8	no signal
661	Blood Calcium Decreased	18	1.8	1.8	no signal
662	Throat Tightness	43	1.8	1.8	no signal
663	Eating Disorder	34	1.8	1.8	no signal
664	Posterior Reversible Encephalopathy Syndrome	15	1.8	1.8	no signal
665	Anxiety	449	1.8	1.8	no signal
666	Dysarthria	59	1.8	1.8	no signal
667	Acidosis	12	1.8	1.8	no signal
668	Hepatic Steatosis	29	1.8	1.8	no signal
669	Affect Lability	15	1.8	1.8	no signal
670	Hepatitis Acute	10	1.8	1.8	no signal
671	Haemorrhoids	30	1.8	1.8	no signal
672	Coma	73	1.8	1.8	no signal
673	Gait Disturbance	291	1.7	1.7	no signal
674	Cholecystitis	18	1.7	1.7	no signal
675	Muscle Twitching	35	1.7	1.7	no signal
676	Pyelonephritis	13	1.7	1.7	no signal
677	Seizure	172	1.7	1.7	no signal
678	Meningitis	10	1.7	1.7	no signal
679	Breast Cancer Metastatic	16	1.7	1.7	no signal
680	Musculoskeletal Chest Pain	23	1.7	1.7	no signal
681	Oropharyngeal Pain	137	1.7	1.7	no signal
682	Productive Cough	70	1.7	1.7	no signal
683	Metastases To Lung	17	1.7	1.7	no signal
684	Back Disorder	24	1.7	1.7	no signal
685	Blood Urine Present	28	1.7	1.7	no signal
686	Respiratory Tract Infection	38	1.7	1.7	no signal
687	Lung Infection	23	1.7	1.7	no signal
688	Hypercalcaemia	18	1.7	1.7	no signal
689	Depression	333	1.7	1.7	no signal
690	Gastrointestinal Infection	13	1.7	1.7	no signal
691	Bone Pain	85	1.7	1.7	no signal
692	Joint Effusion	10	1.7	1.7	no signal
693	Autoimmune Hepatitis	10	1.7	1.7	no signal
694	Nephropathy Toxic	16	1.6	1.6	no signal
695	Adverse Reaction	19	1.6	1.6	no signal
696	Status Epilepticus	16	1.6	1.6	no signal
697	Respiratory Failure	103	1.6	1.6	no signal
698	Gastritis	37	1.6	1.6	no signal
699	Haemoglobin Abnormal	9	1.6	1.6	no signal
700	Cardiogenic Shock	20	1.6	1.6	no signal
701	Neck Pain	78	1.6	1.6	no signal
702	Cough	388	1.6	1.6	no signal
703	Motor Dysfunction	14	1.6	1.6	no signal
704	Neoplasm Progression	48	1.6	1.6	no signal
705	Dizziness	679	1.6	1.6	no signal
706	Melaena	30	1.6	1.6	no signal
707	Therapeutic Product Effect Incomplete	96	1.6	1.6	no signal
708	Anal Incontinence	12	1.5	1.5	no signal
709	Hypertensive Crisis	15	1.5	1.5	no signal
710	Clostridium Difficile Infection	29	1.5	1.5	no signal
711	Bronchitis	99	1.5	1.5	no signal
712	Syncope	133	1.5	1.5	no signal
713	Headache	831	1.5	1.5	no signal
714	Hepatic Failure	40	1.5	1.5	no signal
715	Rash Erythematous	62	1.5	1.5	no signal
716	Bowel Movement Irregularity	10	1.5	1.5	no signal
717	Hyperhidrosis	169	1.5	1.5	no signal
718	Hepatotoxicity	29	1.5	1.5	no signal
719	Bronchopulmonary Aspergillosis	10	1.5	1.5	no signal
720	Therapeutic Response Decreased	78	1.5	1.5	no signal
721	Hemiparesis	22	1.5	1.5	no signal
722	Multiple Organ Dysfunction Syndrome	36	1.5	1.5	no signal
723	Hyperkalaemia	45	1.5	1.5	no signal
724	Pneumonia Aspiration	32	1.5	1.5	no signal
725	Tubulointerstitial Nephritis	24	1.5	1.5	no signal
726	Apnoea	10	1.5	1.5	no signal
727	Torsade De Pointes	10	1.5	1.5	no signal
728	Drug Level Decreased	13	1.5	1.5	no signal
729	Shock	29	1.5	1.5	no signal
730	Myoclonus	15	1.4	1.4	no signal
731	Stevens-johnson Syndrome	28	1.4	1.4	no signal
732	Renal Impairment	105	1.4	1.4	no signal
733	Skin Infection	14	1.4	1.4	no signal
734	Mydriasis	16	1.4	1.4	no signal
735	Hallucination, Visual	26	1.4	1.4	no signal
736	Peripheral Coldness	17	1.4	1.4	no signal
737	Emotional Disorder	38	1.4	1.4	no signal
738	Photosensitivity Reaction	20	1.4	1.4	no signal
739	Disorientation	48	1.4	1.4	no signal
740	Cardiac Failure	97	1.4	1.4	no signal
741	Pharyngitis Streptococcal	13	1.4	1.4	no signal
742	Cold Sweat	21	1.4	1.4	no signal
743	Gastrointestinal Pain	13	1.4	1.4	no signal
744	Rash Macular	41	1.3	1.3	no signal
745	Retching	25	1.3	1.3	no signal
746	Neutrophil Count Increased	12	1.3	1.3	no signal
747	Depressed Level Of Consciousness	46	1.3	1.3	no signal
748	Gastrooesophageal Reflux Disease	93	1.3	1.3	no signal
749	Pharyngeal Oedema	18	1.3	1.3	no signal
750	Staphylococcal Infection	38	1.3	1.3	no signal
751	Convulsion	66	1.3	1.3	no signal
752	Pallor	31	1.3	1.3	no signal
753	Pericardial Effusion	26	1.3	1.3	no signal
754	Photophobia	21	1.3	1.3	no signal
755	Atrial Flutter	9	1.3	1.3	no signal
756	Facial Pain	10	1.3	1.3	no signal
757	Hospice Care	11	1.3	1.3	no signal
758	Eczema	56	1.3	1.3	no signal
759	International Normalised Ratio Increased	32	1.3	1.3	no signal
760	Bradycardia	59	1.3	1.3	no signal
761	Leukocytosis	20	1.3	1.3	no signal
762	Pain In Jaw	31	1.2	1.2	no signal
763	Swollen Tongue	34	1.2	1.2	no signal
764	Renal Failure	145	1.2	1.2	no signal
765	Eosinophil Count Increased	9	1.2	1.2	no signal
766	Rhinorrhoea	69	1.2	1.2	no signal
767	Blood Pressure Decreased	71	1.2	1.2	no signal
768	Thirst	19	1.2	1.2	no signal
769	Blood Potassium Decreased	32	1.2	1.2	no signal
770	Cardiac Arrest	88	1.2	1.2	no signal
771	Hot Flush	80	1.2	1.2	no signal
772	Eosinophilia	18	1.2	1.2	no signal
773	Vasculitis	12	1.2	1.2	no signal
774	Rash Generalised	27	1.2	1.2	no signal
775	Gingival Bleeding	14	1.2	1.2	no signal
776	Pulmonary Mass	15	1.2	1.2	no signal
777	Lethargy	58	1.2	1.2	no signal
778	Pulmonary Thrombosis	11	1.2	1.2	no signal
779	Device Occlusion	14	1.1	1.2	no signal
780	Hypothyroidism	32	1.1	1.1	no signal
781	Ageusia	25	1.1	1.1	no signal
782	Gastric Ulcer	19	1.1	1.1	no signal
783	Anorexia	13	1.1	1.1	no signal
784	Plasma Cell Myeloma	38	1.1	1.1	no signal
785	Ovarian Cancer	9	1.1	1.1	no signal
786	Haematotoxicity	9	1.1	1.1	no signal
787	Angina Pectoris	28	1.1	1.1	no signal
788	No Adverse Event	172	1.1	1.1	no signal
789	Appendicitis	9	1.1	1.1	no signal
790	Cardiomegaly	12	1.1	1.1	no signal
791	Drug Level Increased	16	1.1	1.1	no signal
792	Dermatitis	20	1.1	1.1	no signal
793	Hepatic Encephalopathy	9	1.1	1.1	no signal
794	Acute Myeloid Leukaemia	15	1.1	1.1	no signal
795	Urinary Retention	32	1.1	1.1	no signal
796	Ventricular Extrasystoles	10	1.1	1.1	no signal
797	Local Swelling	17	1.1	1.1	no signal
798	Loss Of Consciousness	123	1.1	1.1	no signal
799	Product Physical Issue	19	1.1	1.1	no signal
800	Upper Gastrointestinal Haemorrhage	16	1.1	1.1	no signal
801	Thrombosis	76	1.1	1.1	no signal
802	Colon Cancer	14	1.1	1.1	no signal
803	Dyspnoea Exertional	35	1.1	1.1	no signal
804	Musculoskeletal Discomfort	16	1.1	1.1	no signal
805	Swelling Face	60	1.1	1.1	no signal
806	Liver Function Test Abnormal	27	1.1	1.1	no signal
807	Diverticulitis	25	1.0	1.0	no signal
808	Increased Appetite	17	1.0	1.0	no signal
809	Treatment Noncompliance	49	1.0	1.0	no signal
810	Psychomotor Hyperactivity	15	1.0	1.0	no signal
811	Dysuria	33	1.0	1.0	no signal
812	Poor Quality Sleep	19	1.0	1.0	no signal
813	Transient Ischaemic Attack	30	1.0	1.0	no signal
814	Mitral Valve Incompetence	10	1.0	1.0	no signal
815	Immunodeficiency	13	1.0	1.0	no signal
816	Cardiomyopathy	13	1.0	1.0	no signal
817	Extrapyramidal Disorder	22	1.0	1.0	no signal
818	Abdominal Distension	91	1.0	1.0	no signal
819	Gastric Haemorrhage	10	1.0	1.0	no signal
820	Diarrhoea Haemorrhagic	8	1.0	1.0	no signal
821	Grand Mal Convulsion	8	1.0	1.0	no signal
822	Haematochezia	47	1.0	1.0	no signal
823	Urinary Tract Infection	145	1.0	1.0	no signal
824	Arteriosclerosis	8	1.0	1.0	no signal
825	Ventricular Tachycardia	14	1.0	1.0	no signal
826	Skin Disorder	28	1.0	1.0	no signal
827	Vertigo	51	1.0	1.0	no signal
828	Product Prescribing Issue	17	1.0	1.0	no signal
829	Presyncope	20	0.9	0.9	no signal
830	Fluid Retention	42	0.9	0.9	no signal
831	Product Packaging Quantity Issue	9	0.9	0.9	no signal
832	Haemoptysis	23	0.9	0.9	no signal
833	Brain Fog	12	0.9	0.9	no signal
834	Drug Reaction With Eosinophilia And Systemic Symptoms	21	0.9	0.9	no signal
835	Mood Swings	26	0.9	0.9	no signal
836	Coeliac Disease	8	0.9	0.9	no signal
837	Hepatomegaly	8	0.9	0.9	no signal
838	Ventricular Fibrillation	9	0.9	0.9	no signal
839	Bacterial Infection	15	0.9	0.9	no signal
840	Haematoma	21	0.9	0.9	no signal
841	Akathisia	11	0.9	0.9	no signal
842	Dermatitis Allergic	10	0.9	0.9	no signal
843	Hypoaesthesia Oral	12	0.9	0.9	no signal
844	Full Blood Count Decreased	16	0.9	0.9	no signal
845	Diabetic Ketoacidosis	19	0.9	0.9	no signal
846	Serotonin Syndrome	15	0.9	0.9	no signal
847	Electrocardiogram Qt Prolonged	28	0.9	0.9	no signal
848	Acute Myocardial Infarction	23	0.9	0.9	no signal
849	Limb Discomfort	24	0.9	0.9	no signal
850	Cellulitis	39	0.9	0.9	no signal
851	Hospitalisation	117	0.9	0.9	no signal
852	Retinal Detachment	7	0.9	0.9	no signal
853	Tinnitus	35	0.9	0.9	no signal
854	Urosepsis	7	0.9	0.9	no signal
855	Pulmonary Congestion	10	0.9	0.9	no signal
856	Ataxia	9	0.9	0.9	no signal
857	Ulcer	12	0.9	0.9	no signal
858	Feeling Cold	21	0.9	0.9	no signal
859	Abscess	12	0.9	0.9	no signal
860	Breast Pain	8	0.9	0.9	no signal
861	Gastrointestinal Haemorrhage	63	0.9	0.9	no signal
862	Inappropriate Schedule Of Drug Administration	54	0.9	0.9	no signal
863	Skin Discolouration	34	0.8	0.8	no signal
864	Sinus Congestion	10	0.8	0.8	no signal
865	Heart Rate Increased	72	0.8	0.8	no signal
866	Cerebral Haemorrhage	26	0.8	0.8	no signal
867	Palpitations	85	0.8	0.8	no signal
868	Flatulence	41	0.8	0.8	no signal
869	Oral Herpes	14	0.8	0.8	no signal
870	Mass	10	0.8	0.8	no signal
871	Blood Pressure Fluctuation	17	0.8	0.8	no signal
872	Body Temperature Decreased	7	0.8	0.8	no signal
873	Dermatitis Contact	8	0.8	0.8	no signal
874	Vision Blurred	96	0.8	0.8	no signal
875	Mental Impairment	17	0.8	0.8	no signal
876	Dry Skin	92	0.8	0.8	no signal
877	Hypotonia	7	0.8	0.8	no signal
878	Skin Lesion	19	0.8	0.8	no signal
879	Rhabdomyolysis	29	0.8	0.8	no signal
880	Pulmonary Oedema	31	0.8	0.8	no signal
881	Splenomegaly	8	0.8	0.8	no signal
882	Lung Neoplasm Malignant	28	0.8	0.8	no signal
883	Sars-cov-2 Test Positive	9	0.8	0.8	no signal
884	Throat Irritation	30	0.8	0.8	no signal
885	Abdominal Pain Lower	17	0.8	0.8	no signal
886	Depressed Mood	35	0.8	0.8	no signal
887	Blood Pressure Systolic Increased	13	0.8	0.8	no signal
888	Toothache	12	0.8	0.8	no signal
889	Gastroenteritis Viral	12	0.8	0.8	no signal
890	Acute Hepatic Failure	9	0.8	0.8	no signal
891	Somnolence	130	0.7	0.7	no signal
892	Lymphoma	10	0.7	0.7	no signal
893	Neoplasm Malignant	43	0.7	0.7	no signal
894	Urinary Incontinence	19	0.7	0.7	no signal
895	Myalgia	109	0.7	0.7	no signal
896	Deformity	6	0.7	0.7	no signal
897	Dysphonia	37	0.7	0.7	no signal
898	Death	543	0.7	0.7	no signal
899	Orthostatic Hypotension	11	0.7	0.7	no signal
900	Product Preparation Error	13	0.7	0.7	no signal
901	Skin Exfoliation	52	0.7	0.7	no signal
902	Myelodysplastic Syndrome	9	0.7	0.7	no signal
903	Rebound Effect	7	0.7	0.7	no signal
904	Blood Potassium Increased	10	0.7	0.7	no signal
905	Parkinsonism	6	0.7	0.7	no signal
906	Tremor	102	0.7	0.7	no signal
907	Nodule	8	0.7	0.7	no signal
908	Drug Ineffective For Unapproved Indication	34	0.7	0.7	no signal
909	Pelvic Pain	11	0.7	0.7	no signal
910	Ocular Hyperaemia	28	0.7	0.7	no signal
911	Quality Of Life Decreased	8	0.7	0.7	no signal
912	Pruritus Generalised	13	0.7	0.7	no signal
913	Poor Quality Product Administered	6	0.7	0.7	no signal
914	Muscle Rigidity	7	0.7	0.7	no signal
915	Pancreatic Carcinoma	17	0.7	0.7	no signal
916	Poor Venous Access	6	0.7	0.7	no signal
917	Drug Toxicity	8	0.7	0.7	no signal
918	Rash Papular	13	0.7	0.7	no signal
919	Feeling Jittery	11	0.7	0.7	no signal
920	Inappropriate Schedule Of Product Administration	101	0.7	0.7	no signal
921	Arrhythmia	27	0.6	0.6	no signal
922	Drug Ineffective	745	0.6	0.6	no signal
923	No Therapeutic Response	7	0.6	0.6	no signal
924	Cystitis	18	0.6	0.6	no signal
925	Injection Site Extravasation	7	0.6	0.6	no signal
926	Hypersomnia	16	0.6	0.6	no signal
927	Muscle Atrophy	7	0.6	0.6	no signal
928	Muscle Tightness	9	0.6	0.6	no signal
929	Drug Administration Error	17	0.6	0.6	no signal
930	Skin Ulcer	14	0.6	0.6	no signal
931	Cytomegalovirus Infection	9	0.6	0.6	no signal
932	Product Packaging Issue	5	0.6	0.6	no signal
933	Feeling Abnormal	129	0.6	0.6	no signal
934	Renal Disorder	25	0.6	0.6	no signal
935	Product Availability Issue	12	0.6	0.6	no signal
936	Haemorrhage Intracranial	8	0.6	0.6	no signal
937	Therapy Partial Responder	8	0.6	0.6	no signal
938	Premature Baby	16	0.6	0.6	no signal
939	Lactic Acidosis	17	0.6	0.6	no signal
940	Agitation	39	0.6	0.6	no signal
941	Complication Associated With Device	7	0.6	0.6	no signal
942	Pollakiuria	22	0.6	0.6	no signal
943	Pharyngeal Swelling	5	0.6	0.6	no signal
944	Angioedema	23	0.6	0.6	no signal
945	Neoplasm	6	0.6	0.6	no signal
946	Dizziness Postural	5	0.6	0.6	no signal
947	Blood Count Abnormal	8	0.6	0.6	no signal
948	Product Quality Issue	70	0.6	0.6	no signal
949	Emotional Distress	63	0.6	0.6	no signal
950	Pain Of Skin	14	0.6	0.6	no signal
951	Foetal Exposure During Pregnancy	42	0.6	0.6	no signal
952	Wrong Technique In Drug Usage Process	19	0.6	0.6	no signal
953	Choking	10	0.6	0.6	no signal
954	Drug Effective For Unapproved Indication	15	0.6	0.6	no signal
955	Psoriasis	67	0.6	0.6	no signal
956	Fungal Infection	17	0.6	0.6	no signal
957	Diabetes Mellitus Inadequate Control	9	0.6	0.6	no signal
958	Circumstance Or Information Capable Of Leading To Medication Error	17	0.6	0.6	no signal
959	Covid-19 Pneumonia	6	0.6	0.6	no signal
960	Salivary Hypersecretion	5	0.6	0.6	no signal
961	Sedation	13	0.6	0.6	no signal
962	Sensory Disturbance	8	0.6	0.6	no signal
963	Dyskinesia	20	0.6	0.6	no signal
964	Blood Pressure Increased	75	0.6	0.6	no signal
965	Cataract	29	0.6	0.6	no signal
966	Lymphadenopathy	17	0.5	0.5	no signal
967	Visual Acuity Reduced	16	0.5	0.5	no signal
968	Respiratory Arrest	13	0.5	0.5	no signal
969	Blindness	19	0.5	0.5	no signal
970	Head Discomfort	8	0.5	0.5	no signal
971	Herpes Zoster	26	0.5	0.5	no signal
972	Incorrect Product Storage	6	0.5	0.5	no signal
973	Nervous System Disorder	14	0.5	0.5	no signal
974	Blood Creatine Phosphokinase Increased	13	0.5	0.5	no signal
975	Incorrect Product Administration Duration	9	0.5	0.5	no signal
976	Osteonecrosis Of Jaw	11	0.5	0.5	no signal
977	Bone Disorder	8	0.5	0.5	no signal
978	Coronary Artery Occlusion	6	0.5	0.5	no signal
979	Brain Neoplasm	4	0.5	0.5	no signal
980	Hypoglycaemia	21	0.5	0.5	no signal
981	Burning Sensation	30	0.5	0.5	no signal
982	Mania	7	0.5	0.5	no signal
983	Diplopia	11	0.5	0.5	no signal
984	Osteonecrosis	14	0.5	0.5	no signal
985	Spinal Disorder	4	0.5	0.5	no signal
986	Viral Infection	14	0.5	0.5	no signal
987	Impaired Work Ability	9	0.5	0.5	no signal
988	Faeces Discoloured	9	0.5	0.5	no signal
989	Therapy Change	4	0.5	0.5	no signal
990	Hallucination	31	0.5	0.5	no signal
991	Apathy	6	0.5	0.5	no signal
992	Inflammatory Bowel Disease	4	0.5	0.5	no signal
993	Fluid Overload	6	0.5	0.5	no signal
994	Cyst	5	0.5	0.5	no signal
995	Bladder Disorder	4	0.5	0.5	no signal
996	Product Administration Error	8	0.5	0.5	no signal
997	Covid-19	70	0.5	0.4	no signal
998	Cerebrovascular Accident	67	0.4	0.4	no signal
999	Eyelid Ptosis	4	0.4	0.4	no signal
1000	Temperature Intolerance	4	0.4	0.4	no signal
1001	Subarachnoid Haemorrhage	4	0.4	0.4	no signal
1002	Lip Swelling	13	0.4	0.4	no signal
1003	Thyroid Disorder	6	0.4	0.4	no signal
1004	Euphoric Mood	4	0.4	0.4	no signal
1005	Product Prescribing Error	9	0.4	0.4	no signal
1006	Drug Dose Omission	63	0.4	0.4	no signal
1007	Dysstasia	11	0.4	0.4	no signal
1008	Premature Delivery	6	0.4	0.4	no signal
1009	Eye Haemorrhage	5	0.4	0.4	no signal
1010	Cholelithiasis	12	0.4	0.4	no signal
1011	Haemorrhage	38	0.4	0.4	no signal
1012	Speech Disorder	19	0.4	0.4	no signal
1013	Tooth Disorder	8	0.4	0.4	no signal
1014	Crying	13	0.4	0.4	no signal
1015	Accidental Overdose	13	0.4	0.4	no signal
1016	Fall	118	0.4	0.4	no signal
1017	Injection Site Mass	13	0.4	0.4	no signal
1018	Gastric Cancer	9	0.4	0.4	no signal
1019	Dry Eye	17	0.4	0.4	no signal
1020	Incorrect Drug Administration Duration	10	0.4	0.4	no signal
1021	Activities Of Daily Living Impaired	7	0.4	0.4	no signal
1022	Subdural Haematoma	5	0.4	0.4	no signal
1023	Metrorrhagia	6	0.4	0.4	no signal
1024	Anosmia	5	0.4	0.4	no signal
1025	Post Procedural Haemorrhage	4	0.4	0.4	no signal
1026	Fear	9	0.4	0.4	no signal
1027	Hypoacusis	14	0.4	0.4	no signal
1028	Delusion	5	0.4	0.4	no signal
1029	Tooth Extraction	4	0.4	0.4	no signal
1030	Overdose	69	0.4	0.4	no signal
1031	Gastric Disorder	11	0.4	0.4	no signal
1032	Diabetes Mellitus	24	0.4	0.4	no signal
1033	Influenza	35	0.4	0.4	no signal
1034	Heart Rate Decreased	11	0.4	0.4	no signal
1035	Drug Resistance	8	0.4	0.4	no signal
1036	Intentional Product Misuse	27	0.4	0.4	no signal
1037	Drug Prescribing Error	6	0.4	0.4	no signal
1038	Chronic Obstructive Pulmonary Disease	16	0.4	0.3	no signal
1039	Inability To Afford Medication	3	0.3	0.3	no signal
1040	Psychotic Disorder	9	0.3	0.3	no signal
1041	Uveitis	4	0.3	0.3	no signal
1042	Eye Discharge	3	0.3	0.3	no signal
1043	Therapy Cessation	15	0.3	0.3	no signal
1044	Dialysis	4	0.3	0.3	no signal
1045	Abnormal Behaviour	11	0.3	0.3	no signal
1046	Toxicity To Various Agents	46	0.3	0.3	no signal
1047	Cardiovascular Disorder	7	0.3	0.3	no signal
1048	Eye Pain	15	0.3	0.3	no signal
1049	Internal Haemorrhage	3	0.3	0.3	no signal
1050	Aggression	13	0.3	0.3	no signal
1051	Surgery	15	0.3	0.3	no signal
1052	Cognitive Disorder	12	0.3	0.3	no signal
1053	Unintentional Medical Device Removal	3	0.3	0.3	no signal
1054	Nervousness	13	0.3	0.3	no signal
1055	Blood Glucose Increased	46	0.3	0.3	no signal
1056	Myocardial Infarction	42	0.3	0.3	no signal
1057	Illness	24	0.3	0.3	no signal
1058	Intentional Drug Misuse	5	0.3	0.3	no signal
1059	Injection Site Induration	3	0.3	0.3	no signal
1060	Product Dispensing Error	5	0.3	0.3	no signal
1061	Skin Burning Sensation	16	0.3	0.3	no signal
1062	Prostatic Specific Antigen Increased	3	0.2	0.2	no signal
1063	Product Dose Omission	14	0.2	0.2	no signal
1064	Balance Disorder	18	0.2	0.2	no signal
1065	Colorectal Cancer	10	0.2	0.2	no signal
1066	Dystonia	4	0.2	0.2	no signal
1067	Breast Cancer	19	0.2	0.2	no signal
1068	Irritability	12	0.2	0.2	no signal
1069	Glycosylated Haemoglobin Increased	5	0.2	0.2	no signal
1070	Drug Dispensing Error	3	0.2	0.2	no signal
1071	Incorrect Route Of Drug Administration	7	0.2	0.2	no signal
1072	Influenza Like Illness	15	0.2	0.2	no signal
1073	Eye Irritation	10	0.2	0.2	no signal
1074	Exposure Via Skin Contact	4	0.2	0.2	no signal
1075	Therapy Interrupted	12	0.2	0.2	no signal
1076	Cardiac Failure Congestive	14	0.2	0.2	no signal
1077	Unevaluable Event	13	0.2	0.2	no signal
1078	Syringe Issue	3	0.2	0.2	no signal
1079	Cardiac Disorder	16	0.2	0.2	no signal
1080	Product Dose Omission Issue	48	0.2	0.2	no signal
1081	Disturbance In Attention	9	0.2	0.2	no signal
1082	Bone Density Decreased	5	0.2	0.2	no signal
1083	Breast Cancer Female	4	0.2	0.2	no signal
1084	Injection Site Reaction	10	0.2	0.2	no signal
1085	Needle Issue	4	0.2	0.2	no signal
1086	Oesophageal Carcinoma	4	0.2	0.2	no signal
1087	Injection Site Rash	4	0.2	0.2	no signal
1088	Acne	10	0.1	0.1	no signal
1089	Hepatic Cancer	3	0.1	0.1	no signal
1090	Suicidal Ideation	11	0.1	0.1	no signal
1091	Chronic Kidney Disease	9	0.1	0.1	no signal
1092	Device Use Error	4	0.1	0.1	no signal
1093	Injection Site Erythema	14	0.1	0.1	no signal
1094	Device Malfunction	7	0.1	0.1	no signal
1095	Device Issue	9	0.1	0.1	no signal
1096	Incorrect Dose Administered	23	0.1	0.1	no signal
1097	Gynaecomastia	3	0.1	0.1	no signal
1098	Product Adhesion Issue	3	0.1	0.1	no signal
1099	Injection Site Pain	23	0.1	0.1	no signal
1100	Device Leakage	3	0.1	0.1	no signal
1101	Wrong Technique In Product Usage Process	13	0.1	0.1	no signal
1102	Bladder Cancer	3	0.1	0.1	no signal