Reaction

Porphyria Acute reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,363 reports · 160 co-occurring drugs

As of the last recalculation, Porphyria Acute appears in 1,363 FAERS reports alongside 160 co-occurring drug terms. The strongest observed disproportionality signal is DICLOFENAC POTASSIUM, FILM COATED (PRR 580.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Diclofenac Potassium, Film Coated	259	580.0	598.5
Diclofenac Potassium Tablets	259	579.6	598.1
Diclofenac Potassium	259	451.6	462.8
Naproxen Sodium Tablet, Coated	242	331.6	337.7
Naproxen Sodium, Coated Tablets	242	331.6	337.7
Naproxen Sodium 220Mg	242	331.1	337.2
Hydrocortisone Sodium Succinate	159	292.3	297.3
Chlorhexidine Gluconate	147	275.3	279.8
Desoximetasone	255	251.2	254.6
Pseudoephedrine Hydrochloride	144	239.2	242.6
Pseudoephedrine Hcl	144	223.0	226.0
Tofacitinib Citrate	164	217.0	219.8
Aprepitant	212	207.5	209.9
Fosaprepitant Dimeglumine	159	199.8	202.1
Cortisone Acetate	135	185.2	187.3
Diclofenac Sodium 1%	320	178.5	180.1
Diclofenac Sodium Topical	320	178.4	180.1
Diclofenac Sodium Topical Gel, 1%	320	178.1	179.7
Acetaminophen And Codeine	115	157.3	158.8
Calcium Gluconate	107	147.1	148.4
Diltiazem Hydrochloride Extended-Release Tablets	100	144.8	146.0
Cetirizine Hydrochloride Allergy	229	138.6	139.6
Cetirizine Hydrochloride Tablets	229	138.6	139.6
Doxyclycline Hyclate	131	129.9	130.9
Erythromycin	134	120.9	121.8
Isopropyl Alcohol	222	119.6	120.4
Oxycodone And Acetaminophen Tablets	77	104.5	105.2
Alcohol	222	104.1	104.7
Quetiapine Fumarate	173	102.4	103.0
Adalimumab-Adaz	262	93.6	94.1
Adalimumab-Fkjp	232	92.0	92.4
Indomethacin	75	91.4	91.9
Adalimumab-Aaty	232	90.0	90.4
Diclofenac	347	82.2	82.5
Sarilumab	128	81.6	82.0
Cetiirizine	181	75.1	75.4
Diphenhydramine Hydrochloride Capsule, Liquid Filled	97	74.6	74.9
Pantoprazole Sodium In 0.9% Sodium Chloride	243	72.6	72.9
Pantoprazole Sodium Injection	243	72.6	72.9
Cetirizine	271	66.3	66.5
Hydrocortisone Acetate	248	63.5	63.7
Leflunomide	328	62.7	62.9
Sulfasalazine	258	61.9	62.1
Triamcinolone Acetonide Ointment Usp, 0.05%	85	59.1	59.3
Anti-Itch	215	58.0	58.1
Anti-Pruritic	215	58.0	58.1
Antipruritic (Anti-Itch)	215	58.0	58.1
Cool Relief Gel With Aloe	215	58.0	58.1
Drs. Hydrocortisone	215	58.0	58.1
Hydrocortisone Continuous Spray	215	58.0	58.1
Hydrocortisone Spray	215	58.0	58.1
Anti-Itch Cream	215	58.0	58.1
Hydrocortisone Lotion	215	58.0	58.1
Hydrocortisone Cream 1%	215	57.9	58.1
Hydrocortisone Cream 1/2%	215	57.9	58.1
Hydrocortisone 1%	215	57.9	58.1
Hydrocortisone Cream	215	57.7	57.8
Alendronate Sodium	295	56.7	56.9
Golimumab	251	54.6	54.7
Oxycodone And Acetaminophen	77	53.4	53.6
Hydroxychloroquine	217	52.6	52.8
Botulinum Toxin Type A	41	52.0	52.1
Tocilizumab	301	51.4	51.6
Hydrocortisone	237	48.9	49.0
Meloxicam	163	48.5	48.7
Diclofenac Sodium	355	48.4	48.5
Diltiazem Hydrochloride	100	47.6	47.7
Calcium Carbonate	177	46.1	46.2
Triamcinolone Acetonide	85	44.7	44.9
Antacid	126	44.5	44.6
Doxycycline Hyclate	172	44.4	44.5
Hydroxychloroquine Sulfate	221	44.0	44.1
Doxycycline	172	43.9	44.0
Trimethoprim	33	43.8	43.9
Mesalamine	144	43.7	43.8
Moxifloxacin Hydrochloride	55	43.1	43.2
Moxifloxacin	38	42.3	42.5
Ustekinumab	229	40.9	41.0
Tramadol Hydrochloride	93	40.4	40.5
Naproxen Sodium	294	39.8	39.9
Ascorbic Acid	56	38.3	38.4
Risedronate Sodium	73	37.8	37.9
Secukinumab	306	37.1	37.1
Certolizumab Pegol	236	37.0	37.1
Ramipril	233	34.4	34.5
Magnesium	160	33.5	33.6
Abatacept	247	33.0	33.1
Icosapent Ethyl	18	32.7	32.8
Cetirizine Hydrochloride	273	31.4	31.4
Vitamin C	166	31.3	31.3
Celecoxib	224	30.9	30.9
Rituximab	326	30.6	30.7
Pantoprazole Sodium	244	30.4	30.4
Mycophenolate Mofetil Hydrochloride	224	29.9	29.9
Mycophenolate Mofetil	223	29.8	29.8
Methylprednisolone Sodium Succinate	85	29.8	29.8
Atomoxetine Hydrochloride	44	29.1	29.2
Morphine	123	27.6	27.6
Lorazepam	262	27.3	27.4
Vedolizumab	136	26.7	26.7
Diphenhydramine	102	26.6	26.6
Candesartan	58	25.9	25.9
Infliximab	289	25.4	25.4
Lansoprazole	240	24.8	24.8
Quetiapine	249	23.9	24.0
Azathioprine	125	23.8	23.8
Tofacitinib	237	23.5	23.6
Naproxen	109	22.9	23.0
Pantoprazole	298	22.7	22.8
Apremilast	185	22.2	22.2
Diphenhydramine Hydrochloride	202	21.7	21.7
Phenytoin	29	21.7	21.7
Acetaminophen Tablet Extended Release	288	21.6	21.6
Pain Reliever	288	21.6	21.6
Acetaminophen 500Mg	288	21.6	21.6
Folic Acid	281	21.4	21.4
Oseltamivir	11	21.3	21.3
Oxycodone Hydrochloride And Acetaminophen	123	20.8	20.8
Cyanocobalamin	42	20.1	20.1
Oxycodone	208	19.9	19.9
Ibuprofen Capsule	208	18.6	18.6
Ibuprofen Tablet, Film Coated	208	18.6	18.6
Ibupfrofen	208	18.6	18.6
Ibuprofen Tablets Usp, 200Mg	208	18.6	18.6
Ibuprofen Oral	208	18.6	18.6
Ibuprofen Capsules 200 Mg	208	18.6	18.6
Ibuprofen 200 Mg	208	18.6	18.6
Ibuprofen 200Mg	208	18.6	18.6
Erenumab-Aooe	64	18.6	18.6
Albuterol	128	17.9	17.9
Fluticasone Furoate	14	17.8	17.8
Mirabegron	43	17.5	17.5
Phenobarbital	16	17.0	17.1
Tretinoin	9	17.0	17.1
Fish Oil	92	16.6	16.6
Sulfamethoxazole And Trimethoprim	85	16.3	16.4
Cyclobenzaprine Hydrochloride	9	15.4	15.4
Prednisolone	160	15.2	15.2
Prednisolone Oral	160	15.2	15.2
Prednisolone Oral Solution	160	15.2	15.2
Ibuprofen	228	15.2	15.2
Mepolizumab	44	13.9	14.0
Pregabalin	206	13.4	13.4
Minocycline	10	13.2	13.2
Calcium	118	13.2	13.2
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	116	12.0	12.0
Lisinopril	207	12.0	12.0
Cyclobenzaprine	36	11.3	11.3
Topiramate	60	10.2	10.2
Ibuprofen Tablets, Coated	27	9.9	9.9
Oxycodone Hydrochloride	128	9.8	9.8
Ibuprofen Sodium	27	9.8	9.8
Adalimumab	328	9.0	9.0
Etanercept	248	7.5	7.5
Buprenorphine	43	7.3	7.3
Clobazam	11	6.9	6.9
Oseltamivir Phosphate	11	6.9	6.9
Ranitidine Hydrochloride	24	6.8	6.8
Lifitegrast	5	4.7	4.7
Salicylic Acid	7	2.0	2.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.