OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Famotidine

1,159 flagged reaction(s) · 455,696 total co-reports · max PRR 51.7
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Chronic Kidney Disease-mineral And Bone Disorder 241 51.7 51.8 signal
2 Nephrogenic Anaemia 880 41.5 41.8 signal
3 Rebound Acid Hypersecretion 552 39.3 39.5 signal
4 Hyperparathyroidism Secondary 440 37.6 37.8 signal
5 Mast Cell Activation Syndrome 189 29.8 29.8 signal
6 End Stage Renal Disease 2,009 21.9 22.3 signal
7 Chronic Kidney Disease 6,660 17.0 18.0 signal
8 Infusion Site Discharge 130 14.7 14.7 signal
9 Accidental Drug Intake By Child 96 11.8 11.8 signal
10 Aplastic Anaemia 306 11.1 11.1 signal
11 Calcium Deficiency 74 10.8 10.8 signal
12 Renal Injury 1,498 9.4 9.5 signal
13 Infusion Site Haemorrhage 151 8.7 8.7 signal
14 Infusion Site Swelling 262 7.9 8.0 signal
15 Infusion Site Pruritus 129 7.7 7.7 signal
16 Tubulointerstitial Nephritis 747 7.4 7.5 signal
17 Infusion Site Bruising 84 7.3 7.3 signal
18 Device Infusion Issue 90 6.8 6.8 signal
19 Infusion Site Pain 466 6.8 6.8 signal
20 Gastrointestinal Hypomotility 80 6.6 6.6 signal
21 Infusion Site Erythema 296 6.6 6.6 signal
22 Essential Hypertension 89 6.4 6.4 signal
23 Impaired Gastric Emptying 413 6.0 6.0 signal
24 Infusion Site Infection 73 5.9 5.9 signal
25 Gastrooesophageal Reflux Disease 2,528 5.8 5.9 signal
26 Rhinovirus Infection 119 5.8 5.8 signal
27 Acute Kidney Injury 4,727 5.7 5.9 signal
28 Renal Failure 4,119 5.7 5.8 signal
29 Nephropathy 280 5.5 5.5 signal
30 Hypervolaemia 143 5.5 5.5 signal
31 Peptic Ulcer 97 5.4 5.4 signal
32 Seasonal Allergy 399 5.2 5.2 signal
33 Atelectasis 267 5.1 5.1 signal
34 Infusion Site Reaction 80 5.1 5.1 signal
35 Product Administration Interrupted 207 5.0 5.0 signal
36 Monocyte Count Increased 96 4.8 4.8 signal
37 Vitamin D Deficiency 253 4.8 4.8 signal
38 Cholecystitis Chronic 176 4.8 4.8 signal
39 Renal Tubular Necrosis 255 4.8 4.8 signal
40 Metabolic Encephalopathy 77 4.7 4.7 signal
41 Acute Respiratory Failure 486 4.7 4.7 signal
42 Vascular Device Infection 114 4.6 4.6 signal
43 Cholecystitis Acute 141 4.6 4.6 signal
44 Pharyngeal Swelling 237 4.5 4.5 signal
45 Vitamin B12 Deficiency 97 4.4 4.4 signal
46 Intervertebral Disc Degeneration 220 4.3 4.3 signal
47 Blood Magnesium Decreased 204 4.3 4.3 signal
48 Type I Hypersensitivity 82 4.3 4.3 signal
49 Spinal Osteoarthritis 205 4.2 4.2 signal
50 Disseminated Intravascular Coagulation 327 4.2 4.2 signal
51 Protein Total Decreased 87 4.2 4.2 signal
52 Bone Lesion 82 4.2 4.2 signal
53 Diverticulum Intestinal 96 4.0 4.0 signal
54 Blood Albumin Decreased 174 4.0 4.0 signal
55 Haemoglobin Increased 99 4.0 4.0 signal
56 Blood Lactate Dehydrogenase Increased 339 3.9 3.9 signal
57 Osteopenia 323 3.9 3.9 signal
58 Rhinitis Allergic 94 3.9 3.9 signal
59 Aortic Valve Incompetence 90 3.8 3.8 signal
60 Hypophosphataemia 154 3.8 3.8 signal
61 Staphylococcal Bacteraemia 90 3.8 3.8 signal
62 Dermatitis Contact 235 3.8 3.8 signal
63 Hypovolaemia 121 3.8 3.8 signal
64 Food Allergy 156 3.8 3.8 signal
65 Economic Problem 318 3.8 3.8 signal
66 Blood Urea Increased 347 3.8 3.8 signal
67 Left Ventricular Hypertrophy 88 3.7 3.7 signal
68 Mouth Haemorrhage 150 3.7 3.7 signal
69 Hyperuricaemia 83 3.7 3.7 signal
70 Haematocrit Decreased 402 3.7 3.7 signal
71 Hypomagnesaemia 278 3.7 3.7 signal
72 Brain Fog 292 3.6 3.7 signal
73 Hereditary Angioedema 210 3.6 3.6 signal
74 Hiatus Hernia 258 3.6 3.6 signal
75 Hospice Care 195 3.6 3.6 signal
76 Cytokine Release Syndrome 377 3.6 3.6 signal
77 Tricuspid Valve Incompetence 156 3.6 3.6 signal
78 Multiple Allergies 154 3.6 3.6 signal
79 Enterocolitis 112 3.6 3.6 signal
80 Anaphylactic Reaction 1,071 3.6 3.6 signal
81 Hypoalbuminaemia 148 3.5 3.5 signal
82 Periorbital Swelling 106 3.5 3.5 signal
83 Dyspepsia 1,893 3.5 3.6 signal
84 Gastritis 507 3.5 3.5 signal
85 Epigastric Discomfort 75 3.5 3.5 signal
86 Red Cell Distribution Width Increased 79 3.5 3.5 signal
87 Impaired Quality Of Life 272 3.4 3.4 signal
88 Physical Disability 84 3.4 3.4 signal
89 Febrile Neutropenia 1,238 3.4 3.4 signal
90 Renal Failure Chronic 145 3.4 3.4 signal
91 Clostridium Difficile Colitis 197 3.4 3.4 signal
92 Hyperlipidaemia 221 3.4 3.4 signal
93 Weight Fluctuation 192 3.4 3.4 signal
94 Anhedonia 486 3.3 3.3 signal
95 Hepatic Function Abnormal 678 3.3 3.3 signal
96 Hypoxia 638 3.3 3.3 signal
97 Post-traumatic Stress Disorder 122 3.3 3.3 signal
98 Blood Pressure Systolic Decreased 82 3.3 3.3 signal
99 Aspartate Aminotransferase Increased 959 3.3 3.3 signal
100 Kidney Transplant Rejection 87 3.3 3.3 signal
101 Synovial Cyst 83 3.2 3.3 signal
102 Blood Uric Acid Increased 103 3.2 3.2 signal
103 Renal Cyst 142 3.2 3.2 signal
104 Malnutrition 198 3.2 3.2 signal
105 Pre-existing Condition Improved 111 3.2 3.2 signal
106 Mitral Valve Incompetence 199 3.2 3.2 signal
107 Diverticulum 126 3.2 3.2 signal
108 Failure To Thrive 91 3.2 3.2 signal
109 Blood Alkaline Phosphatase Increased 432 3.2 3.2 signal
110 Pneumonia Bacterial 158 3.1 3.1 signal
111 Compression Fracture 90 3.1 3.1 signal
112 Infusion Related Reaction 1,135 3.1 3.1 signal
113 Pathological Fracture 87 3.1 3.1 signal
114 Lung Infiltration 152 3.1 3.1 signal
115 Respiratory Syncytial Virus Infection 147 3.1 3.1 signal
116 Diabetic Neuropathy 84 3.1 3.1 signal
117 Upper-airway Cough Syndrome 138 3.1 3.1 signal
118 Mucosal Inflammation 435 3.0 3.0 signal
119 Decubitus Ulcer 136 3.0 3.0 signal
120 Cardiomegaly 207 3.0 3.0 signal
121 Spinal Compression Fracture 140 3.0 3.0 signal
122 Blood Potassium Decreased 499 3.0 3.0 signal
123 Red Blood Cell Count Decreased 472 3.0 3.0 signal
124 Alanine Aminotransferase Increased 1,007 3.0 3.0 signal
125 Peripheral Vascular Disorder 85 3.0 3.0 signal
126 Staphylococcal Sepsis 81 3.0 3.0 signal
127 Iron Deficiency Anaemia 150 3.0 3.0 signal
128 Mental Status Changes 453 3.0 3.0 signal
129 Infective Pulmonary Exacerbation Of Cystic Fibrosis 89 2.9 2.9 signal
130 Osteoporosis 668 2.9 3.0 signal
131 Small Intestinal Obstruction 199 2.9 2.9 signal
132 Urine Output Decreased 142 2.9 2.9 signal
133 Insurance Issue 239 2.9 2.9 signal
134 Sinus Tachycardia 226 2.9 2.9 signal
135 Multiple Myeloma 75 2.9 2.9 signal
136 Pulmonary Hypertension 331 2.9 2.9 signal
137 Pneumothorax 249 2.8 2.9 signal
138 Covid-19 Pneumonia 186 2.8 2.8 signal
139 Upper Respiratory Tract Infection 722 2.8 2.8 signal
140 Blood Sodium Decreased 294 2.8 2.8 signal
141 Platelet Count Decreased 1,658 2.8 2.8 signal
142 Torsade De Pointes 122 2.8 2.8 signal
143 Scoliosis 96 2.8 2.8 signal
144 Ventricular Tachycardia 256 2.8 2.8 signal
145 Ileus 190 2.8 2.8 signal
146 Lymphocyte Count Decreased 273 2.8 2.8 signal
147 Polyp 101 2.8 2.8 signal
148 Neutrophil Count Decreased 624 2.8 2.8 signal
149 Hyperkeratosis 85 2.8 2.8 signal
150 Oxygen Saturation Decreased 855 2.8 2.8 signal
151 Pneumonia Aspiration 380 2.8 2.8 signal
152 Angina Unstable 100 2.8 2.8 signal
153 Taste Disorder 305 2.8 2.8 signal
154 Prothrombin Time Prolonged 92 2.8 2.8 signal
155 Bone Disorder 279 2.8 2.8 signal
156 Oral Candidiasis 197 2.7 2.7 signal
157 Throat Tightness 409 2.7 2.8 signal
158 Oropharyngeal Discomfort 135 2.7 2.7 signal
159 Psychological Trauma 132 2.7 2.7 signal
160 Hypokalaemia 684 2.7 2.7 signal
161 Bacteraemia 175 2.7 2.7 signal
162 Gallbladder Disorder 266 2.7 2.7 signal
163 Sleep Apnoea Syndrome 284 2.7 2.7 signal
164 Activated Partial Thromboplastin Time Prolonged 75 2.7 2.7 signal
165 Protein Urine Present 73 2.7 2.7 signal
166 Abdominal Tenderness 73 2.7 2.7 signal
167 Flank Pain 137 2.7 2.7 signal
168 Nerve Compression 134 2.6 2.6 signal
169 Arteriosclerosis 137 2.6 2.6 signal
170 Dizziness Postural 139 2.6 2.6 signal
171 Inappropriate Antidiuretic Hormone Secretion 147 2.6 2.6 signal
172 Appetite Disorder 94 2.6 2.6 signal
173 White Blood Cell Count Increased 552 2.6 2.6 signal
174 Oesophagitis 156 2.6 2.6 signal
175 Nocturia 172 2.6 2.6 signal
176 Hydronephrosis 106 2.6 2.6 signal
177 Cystic Fibrosis 79 2.6 2.6 signal
178 Decreased Activity 152 2.6 2.6 signal
179 Blood Bilirubin Increased 384 2.6 2.6 signal
180 Skin Laceration 153 2.6 2.6 signal
181 Throat Irritation 633 2.6 2.6 signal
182 Gastrointestinal Motility Disorder 75 2.6 2.6 signal
183 Musculoskeletal Chest Pain 219 2.6 2.6 signal
184 Hyperchlorhydria 84 2.6 2.6 signal
185 Multiple Fractures 234 2.6 2.6 signal
186 Supraventricular Tachycardia 135 2.6 2.6 signal
187 Blood Calcium Decreased 159 2.6 2.6 signal
188 Gastric Ulcer 268 2.5 2.6 signal
189 Faeces Discoloured 305 2.5 2.6 signal
190 Foot Fracture 267 2.5 2.5 signal
191 Dyspnoea Exertional 526 2.5 2.5 signal
192 Cholelithiasis 459 2.5 2.5 signal
193 Hiccups 114 2.5 2.5 signal
194 Tumour Lysis Syndrome 122 2.5 2.5 signal
195 Cholecystitis 165 2.5 2.5 signal
196 Heart Rate Abnormal 77 2.5 2.5 signal
197 Infusion Site Extravasation 86 2.5 2.5 signal
198 Pleural Effusion 842 2.5 2.5 signal
199 White Blood Cell Count Abnormal 88 2.5 2.5 signal
200 Blood Potassium Increased 224 2.5 2.5 signal
201 Multi-organ Failure 242 2.5 2.5 signal
202 Anorexia 180 2.5 2.5 signal
203 Concomitant Disease Aggravated 85 2.5 2.5 signal
204 Acidosis 105 2.5 2.5 signal
205 Dehydration 1,829 2.5 2.5 signal
206 Transfusion 144 2.5 2.5 signal
207 Leukocytosis 247 2.5 2.5 signal
208 Vitamin D Decreased 117 2.5 2.5 signal
209 Emphysema 138 2.5 2.5 signal
210 Gastroenteritis 198 2.5 2.5 signal
211 Respiratory Failure 991 2.5 2.5 signal
212 Electrolyte Imbalance 156 2.5 2.5 signal
213 Increased Tendency To Bruise 125 2.5 2.5 signal
214 Constipation 2,933 2.5 2.5 signal
215 Renal Impairment 1,134 2.5 2.5 signal
216 Eructation 257 2.4 2.4 signal
217 Blood Iron Decreased 159 2.4 2.4 signal
218 Atrial Flutter 108 2.4 2.4 signal
219 Faecaloma 73 2.4 2.4 signal
220 Rotator Cuff Syndrome 173 2.4 2.4 signal
221 Interstitial Lung Disease 646 2.4 2.4 signal
222 Ventricular Extrasystoles 139 2.4 2.4 signal
223 Cellulitis 674 2.4 2.4 signal
224 Eosinophil Count Increased 111 2.4 2.4 signal
225 Drug Screen Positive 105 2.4 2.4 signal
226 Ecchymosis 91 2.4 2.4 signal
227 Colitis Ischaemic 89 2.4 2.4 signal
228 Pseudomonas Infection 112 2.4 2.4 signal
229 Haemorrhoids 258 2.4 2.4 signal
230 Poor Venous Access 136 2.4 2.4 signal
231 Ligament Sprain 130 2.4 2.4 signal
232 Respiration Abnormal 90 2.4 2.4 signal
233 Clostridium Difficile Infection 285 2.4 2.4 signal
234 Product Dose Omission In Error 353 2.4 2.4 signal
235 Urinary Tract Infection 2,232 2.4 2.4 signal
236 Blood Pressure Diastolic Decreased 97 2.4 2.4 signal
237 Flatulence 739 2.4 2.4 signal
238 Blood Creatinine Increased 848 2.3 2.4 signal
239 Sepsis 1,446 2.3 2.4 signal
240 Haemoptysis 362 2.3 2.3 signal
241 Encephalopathy 317 2.3 2.3 signal
242 Osteoarthritis 549 2.3 2.3 signal
243 Dermatitis Acneiform 78 2.3 2.3 signal
244 Right Ventricular Failure 91 2.3 2.3 signal
245 Mouth Swelling 74 2.3 2.3 signal
246 Haemoglobin Decreased 1,322 2.3 2.3 signal
247 Neutrophil Count Increased 132 2.3 2.3 signal
248 Chest Discomfort 1,309 2.3 2.3 signal
249 Hair Colour Changes 161 2.3 2.3 signal
250 Musculoskeletal Discomfort 219 2.3 2.3 signal
251 Haemodialysis 108 2.3 2.3 signal
252 Hand Fracture 90 2.3 2.3 signal
253 Anal Incontinence 113 2.3 2.3 signal
254 Electrocardiogram Abnormal 100 2.3 2.3 signal
255 Generalised Oedema 156 2.3 2.3 signal
256 Pain In Jaw 359 2.3 2.3 signal
257 Tenderness 132 2.3 2.3 signal
258 Splenomegaly 148 2.3 2.3 signal
259 Carpal Tunnel Syndrome 177 2.3 2.3 signal
260 Retching 268 2.3 2.3 signal
261 Rales 73 2.3 2.3 signal
262 Oral Pain 282 2.3 2.3 signal
263 Therapeutic Response Unexpected 565 2.3 2.3 signal
264 Gastroenteritis Viral 227 2.3 2.3 signal
265 Walking Aid User 83 2.3 2.3 signal
266 Lower Gastrointestinal Haemorrhage 93 2.3 2.3 signal
267 Liver Disorder 555 2.3 2.3 signal
268 White Blood Cell Count Decreased 1,358 2.3 2.3 signal
269 Dry Throat 127 2.3 2.3 signal
270 Hepatic Steatosis 232 2.3 2.3 signal
271 Troponin Increased 94 2.3 2.3 signal
272 Blood Pressure Abnormal 246 2.2 2.2 signal
273 Product Distribution Issue 110 2.2 2.2 signal
274 Arteriosclerosis Coronary Artery 82 2.2 2.2 signal
275 Intentional Dose Omission 338 2.2 2.2 signal
276 Sinus Disorder 245 2.2 2.2 signal
277 Full Blood Count Decreased 249 2.2 2.2 signal
278 Cardiac Failure Acute 82 2.2 2.2 signal
279 Toxic Epidermal Necrolysis 186 2.2 2.2 signal
280 Postoperative Wound Infection 83 2.2 2.2 signal
281 Bronchitis 915 2.2 2.2 signal
282 Major Depression 90 2.2 2.2 signal
283 Atrioventricular Block Complete 82 2.2 2.2 signal
284 Rib Fracture 252 2.2 2.2 signal
285 Arthropod Bite 90 2.2 2.2 signal
286 Productive Cough 579 2.2 2.2 signal
287 Lip Swelling 406 2.2 2.2 signal
288 Flushing 1,246 2.2 2.2 signal
289 Coronary Artery Occlusion 168 2.2 2.2 signal
290 Aspiration 132 2.2 2.2 signal
291 Intervertebral Disc Protrusion 267 2.2 2.2 signal
292 Nasal Congestion 711 2.2 2.2 signal
293 Ear Infection 322 2.2 2.2 signal
294 Coronary Artery Disease 370 2.2 2.2 signal
295 Platelet Count Abnormal 73 2.2 2.2 signal
296 Stomatitis 731 2.2 2.2 signal
297 Pulmonary Mass 179 2.2 2.2 signal
298 Hyperkalaemia 420 2.2 2.2 signal
299 Adrenal Insufficiency 144 2.2 2.2 signal
300 Meniscus Injury 74 2.2 2.2 signal
301 Proctalgia 77 2.2 2.2 signal
302 Renal Failure Acute 516 2.2 2.2 signal
303 Sinus Bradycardia 116 2.2 2.2 signal
304 Covid-19 2,110 2.2 2.2 signal
305 Acute Respiratory Distress Syndrome 211 2.2 2.2 signal
306 Viral Infection 395 2.1 2.2 signal
307 Oral Discomfort 165 2.1 2.1 signal
308 Urosepsis 109 2.1 2.1 signal
309 Respiratory Distress 326 2.1 2.1 signal
310 Decreased Appetite 2,731 2.1 2.2 signal
311 Pulmonary Oedema 527 2.1 2.1 signal
312 Temperature Intolerance 120 2.1 2.1 signal
313 Illness 1,180 2.1 2.1 signal
314 Ear Pain 228 2.1 2.1 signal
315 Cerebral Infarction 286 2.1 2.1 signal
316 Erythema Multiforme 109 2.1 2.1 signal
317 Myasthenia Gravis 92 2.1 2.1 signal
318 Ulcer 186 2.1 2.1 signal
319 Respiratory Tract Infection 303 2.1 2.1 signal
320 Blood Pressure Decreased 773 2.1 2.1 signal
321 Respiratory Tract Congestion 185 2.1 2.1 signal
322 Swollen Tongue 363 2.1 2.1 signal
323 Sensation Of Foreign Body 97 2.1 2.1 signal
324 Epistaxis 866 2.1 2.1 signal
325 Gingival Pain 92 2.1 2.1 signal
326 Tongue Disorder 84 2.1 2.1 signal
327 Urticaria 1,917 2.1 2.1 signal
328 Abdominal Distension 1,197 2.1 2.1 signal
329 Irritable Bowel Syndrome 246 2.1 2.1 signal
330 Hypophagia 292 2.1 2.1 signal
331 Upper Gastrointestinal Haemorrhage 194 2.1 2.1 signal
332 Atrial Fibrillation 1,120 2.1 2.1 signal
333 Pneumonitis 310 2.1 2.1 signal
334 Multiple Injuries 73 2.1 2.1 signal
335 Post Procedural Complication 220 2.1 2.1 signal
336 Cardiac Flutter 74 2.1 2.1 signal
337 Sputum Discoloured 108 2.1 2.1 signal
338 Incontinence 121 2.1 2.1 signal
339 Cystitis 365 2.1 2.1 signal
340 Gout 205 2.1 2.1 signal
341 Paraesthesia Oral 164 2.1 2.1 signal
342 Device Related Infection 176 2.1 2.1 signal
343 Sinusitis 1,172 2.1 2.1 signal
344 Neck Pain 638 2.1 2.1 signal
345 Pneumonia 3,684 2.1 2.1 signal
346 Osteomyelitis 206 2.1 2.1 signal
347 Neuralgia 276 2.1 2.1 signal
348 Incorrect Product Administration Duration 230 2.0 2.0 signal
349 Chest Pain 2,103 2.0 2.1 signal
350 Ascites 333 2.0 2.0 signal
351 Pancytopenia 630 2.0 2.0 signal
352 Dysphagia 1,069 2.0 2.0 signal
353 Abdominal Pain Upper 2,320 2.0 2.1 signal
354 Ankle Fracture 175 2.0 2.0 signal
355 Feeding Disorder 225 2.0 2.0 signal
356 Cough 3,155 2.0 2.1 signal
357 Cardiac Murmur 98 2.0 2.0 signal
358 Nephrolithiasis 515 2.0 2.0 signal
359 Drug Eruption 198 2.0 2.0 signal
360 Ventricular Fibrillation 125 2.0 2.0 signal
361 Graft Versus Host Disease 81 2.0 2.0 signal
362 Faeces Soft 81 2.0 2.0 signal
363 Internal Haemorrhage 128 2.0 2.0 signal
364 Colitis 421 2.0 2.0 signal
365 Exposure During Pregnancy 694 2.0 2.0 signal
366 Sinus Congestion 151 2.0 2.0 signal
367 Chronic Obstructive Pulmonary Disease 580 2.0 2.0 signal
368 Anaemia 2,122 2.0 2.0 signal
369 Fluid Overload 164 2.0 2.0 signal
370 Wrist Fracture 133 2.0 2.0 signal
371 Quality Of Life Decreased 149 2.0 2.0 signal
372 Gamma-glutamyltransferase Increased 246 2.0 2.0 signal
373 Gastrointestinal Infection 99 2.0 2.0 signal
374 Tachypnoea 150 2.0 2.0 no signal
375 Hyperbilirubinaemia 114 2.0 2.0 no signal
376 Tooth Abscess 113 2.0 2.0 no signal
377 Neuropathy Peripheral 1,045 2.0 2.0 no signal
378 Restless Legs Syndrome 201 2.0 2.0 no signal
379 Hair Disorder 92 2.0 2.0 no signal
380 Lymphoedema 76 2.0 2.0 no signal
381 Dysphonia 643 2.0 2.0 no signal
382 Body Height Decreased 119 2.0 2.0 no signal
383 Tooth Infection 145 2.0 2.0 no signal
384 Back Pain 2,547 2.0 2.0 no signal
385 Coagulopathy 182 2.0 2.0 no signal
386 Pulmonary Congestion 145 2.0 2.0 no signal
387 Eating Disorder 234 2.0 2.0 no signal
388 Micturition Urgency 124 2.0 2.0 no signal
389 Unresponsive To Stimuli 281 2.0 2.0 no signal
390 Oedema 591 2.0 2.0 no signal
391 Diarrhoea 7,011 2.0 2.0 no signal
392 Back Injury 118 2.0 2.0 no signal
393 Glomerular Filtration Rate Decreased 132 2.0 2.0 no signal
394 Embolism 91 2.0 2.0 no signal
395 Bowel Movement Irregularity 83 2.0 2.0 no signal
396 Heart Rate Increased 1,076 2.0 2.0 no signal
397 Dental Caries 120 2.0 2.0 no signal
398 Hypocalcaemia 205 2.0 2.0 no signal
399 Spinal Disorder 103 2.0 2.0 no signal
400 Abdominal Discomfort 1,813 2.0 2.0 no signal
401 Large Intestine Polyp 75 2.0 2.0 no signal
402 Hyponatraemia 608 2.0 2.0 no signal
403 Septic Shock 467 2.0 2.0 no signal
404 Large Intestine Perforation 75 1.9 1.9 no signal
405 Platelet Count Increased 141 1.9 1.9 no signal
406 Sars-cov-2 Test Positive 144 1.9 1.9 no signal
407 Bacterial Infection 200 1.9 1.9 no signal
408 Ear Discomfort 110 1.9 1.9 no signal
409 Skin Ulcer 276 1.9 1.9 no signal
410 Diverticulitis 295 1.9 1.9 no signal
411 Subarachnoid Haemorrhage 109 1.9 1.9 no signal
412 Hypercholesterolaemia 102 1.9 1.9 no signal
413 Tachycardia 944 1.9 1.9 no signal
414 Rhinorrhoea 684 1.9 1.9 no signal
415 Hair Texture Abnormal 143 1.9 1.9 no signal
416 Chills 1,244 1.9 1.9 no signal
417 Bipolar Disorder 116 1.9 1.9 no signal
418 Vitreous Floaters 103 1.9 1.9 no signal
419 Haemolytic Anaemia 95 1.9 1.9 no signal
420 Renal Disorder 493 1.9 1.9 no signal
421 Respiratory Rate Increased 94 1.9 1.9 no signal
422 Eye Pain 581 1.9 1.9 no signal
423 Dysuria 387 1.9 1.9 no signal
424 Candida Infection 175 1.9 1.9 no signal
425 Hypersomnia 300 1.9 1.9 no signal
426 Delirium 361 1.9 1.9 no signal
427 Oropharyngeal Pain 965 1.9 1.9 no signal
428 Muscle Strain 90 1.9 1.9 no signal
429 Gastrointestinal Pain 114 1.9 1.9 no signal
430 Cholecystectomy 118 1.9 1.9 no signal
431 Polyuria 85 1.9 1.9 no signal
432 Anxiety 2,958 1.9 1.9 no signal
433 Duodenal Ulcer 73 1.9 1.9 no signal
434 Abdominal Pain 2,404 1.9 1.9 no signal
435 Obesity 165 1.9 1.9 no signal
436 Limb Injury 280 1.9 1.9 no signal
437 Bone Pain 606 1.9 1.9 no signal
438 Pyelonephritis 89 1.9 1.9 no signal
439 Oedema Peripheral 1,260 1.9 1.9 no signal
440 Heart Rate Irregular 234 1.9 1.9 no signal
441 Urinary Incontinence 304 1.9 1.9 no signal
442 Blood Calcium Increased 90 1.8 1.8 no signal
443 Spinal Operation 124 1.8 1.8 no signal
444 Hepatomegaly 101 1.8 1.8 no signal
445 Hypotension 2,048 1.8 1.9 no signal
446 Toothache 185 1.8 1.8 no signal
447 Dry Eye 495 1.8 1.8 no signal
448 Injury 721 1.8 1.8 no signal
449 Bursitis 123 1.8 1.8 no signal
450 Exostosis 93 1.8 1.8 no signal
451 Thyroid Disorder 157 1.8 1.8 no signal
452 Hypothyroidism 324 1.8 1.8 no signal
453 Peripheral Swelling 1,560 1.8 1.8 no signal
454 Acute Myocardial Infarction 301 1.8 1.8 no signal
455 Cardiac Failure Congestive 824 1.8 1.8 no signal
456 Transient Ischaemic Attack 344 1.8 1.8 no signal
457 Pyrexia 3,514 1.8 1.9 no signal
458 Fluid Retention 516 1.8 1.8 no signal
459 Vomiting 4,751 1.8 1.9 no signal
460 Secretion Discharge 125 1.8 1.8 no signal
461 Groin Pain 89 1.8 1.8 no signal
462 Staphylococcal Infection 334 1.8 1.8 no signal
463 Blood Pressure Increased 1,542 1.8 1.8 no signal
464 Altered State Of Consciousness 216 1.8 1.8 no signal
465 Myocardial Ischaemia 115 1.8 1.8 no signal
466 Thirst 178 1.8 1.8 no signal
467 Laboratory Test Abnormal 294 1.8 1.8 no signal
468 International Normalised Ratio Increased 287 1.8 1.8 no signal
469 Blood Thyroid Stimulating Hormone Increased 92 1.8 1.8 no signal
470 Photophobia 186 1.8 1.8 no signal
471 Joint Injury 213 1.8 1.8 no signal
472 Subdural Haematoma 143 1.8 1.8 no signal
473 Drug Effect Less Than Expected 140 1.8 1.8 no signal
474 Dyspnoea 5,610 1.8 1.8 no signal
475 Presyncope 240 1.8 1.8 no signal
476 Complication Associated With Device 131 1.8 1.8 no signal
477 Pericardial Effusion 228 1.8 1.8 no signal
478 Sciatica 157 1.8 1.8 no signal
479 Tooth Fracture 109 1.8 1.8 no signal
480 Nausea 7,797 1.8 1.8 no signal
481 Dry Mouth 800 1.8 1.8 no signal
482 Stevens-johnson Syndrome 220 1.8 1.8 no signal
483 Pharyngitis 123 1.8 1.8 no signal
484 Ocular Discomfort 107 1.8 1.8 no signal
485 Hernia 189 1.8 1.8 no signal
486 Pulmonary Arterial Hypertension 143 1.8 1.8 no signal
487 Eye Infection 110 1.8 1.8 no signal
488 Rhinitis 79 1.8 1.8 no signal
489 Intestinal Obstruction 367 1.8 1.8 no signal
490 Pharyngitis Streptococcal 106 1.8 1.8 no signal
491 Blood Test Abnormal 137 1.8 1.8 no signal
492 Facial Pain 87 1.8 1.8 no signal
493 Product Use Complaint 151 1.8 1.8 no signal
494 Face Oedema 165 1.8 1.8 no signal
495 Hypercalcaemia 120 1.8 1.8 no signal
496 Weight Decreased 2,712 1.8 1.8 no signal
497 Shock Haemorrhagic 79 1.8 1.8 no signal
498 Thrombocytopenia 1,083 1.8 1.8 no signal
499 Wheezing 574 1.7 1.8 no signal
500 Middle Insomnia 180 1.7 1.7 no signal
501 Haematuria 331 1.7 1.7 no signal
502 Blood Pressure Fluctuation 232 1.7 1.7 no signal
503 Kidney Infection 189 1.7 1.7 no signal
504 Hepatic Encephalopathy 90 1.7 1.7 no signal
505 Arthritis 759 1.7 1.7 no signal
506 Hypoaesthesia Oral 145 1.7 1.7 no signal
507 Gastrointestinal Haemorrhage 808 1.7 1.7 no signal
508 Brain Oedema 121 1.7 1.7 no signal
509 Muscle Tightness 155 1.7 1.7 no signal
510 Shock 218 1.7 1.7 no signal
511 Bladder Disorder 95 1.7 1.7 no signal
512 Escherichia Infection 78 1.7 1.7 no signal
513 Deep Vein Thrombosis 622 1.7 1.7 no signal
514 Skin Infection 106 1.7 1.7 no signal
515 Eye Discharge 97 1.7 1.7 no signal
516 Palmar-plantar Erythrodysaesthesia Syndrome 222 1.7 1.7 no signal
517 Swelling Face 617 1.7 1.7 no signal
518 C-reactive Protein Increased 345 1.7 1.7 no signal
519 Hip Fracture 304 1.7 1.7 no signal
520 Fatigue 7,353 1.7 1.8 no signal
521 Cardiomyopathy 140 1.7 1.7 no signal
522 Back Disorder 154 1.7 1.7 no signal
523 Spinal Fracture 188 1.7 1.7 no signal
524 Pulmonary Thrombosis 103 1.7 1.7 no signal
525 Swelling 880 1.7 1.7 no signal
526 Petechiae 98 1.7 1.7 no signal
527 Metastases To Liver 165 1.7 1.7 no signal
528 Depression 2,150 1.7 1.7 no signal
529 Lacrimation Increased 281 1.7 1.7 no signal
530 Blood Pressure Systolic Increased 184 1.7 1.7 no signal
531 Hyperglycaemia 341 1.7 1.7 no signal
532 Localised Infection 227 1.7 1.7 no signal
533 Immunodeficiency 138 1.7 1.7 no signal
534 Asthenia 3,522 1.7 1.7 no signal
535 Body Temperature Decreased 93 1.7 1.7 no signal
536 Head Injury 295 1.7 1.7 no signal
537 Lethargy 537 1.7 1.7 no signal
538 Body Temperature Increased 191 1.7 1.7 no signal
539 Migraine 885 1.7 1.7 no signal
540 Initial Insomnia 95 1.7 1.7 no signal
541 Haematemesis 236 1.7 1.7 no signal
542 Proteinuria 175 1.7 1.7 no signal
543 Palpitations 1,081 1.7 1.7 no signal
544 Rectal Haemorrhage 398 1.7 1.7 no signal
545 Acute Coronary Syndrome 77 1.7 1.7 no signal
546 Hypertension 1,955 1.7 1.7 no signal
547 Mass 129 1.7 1.7 no signal
548 Full Blood Count Abnormal 97 1.7 1.7 no signal
549 Product Dose Omission Issue 2,618 1.7 1.7 no signal
550 Muscular Weakness 1,043 1.7 1.7 no signal
551 Angioedema 405 1.7 1.7 no signal
552 Anaphylactic Shock 235 1.7 1.7 no signal
553 Pancreatitis Acute 204 1.6 1.6 no signal
554 Peripheral Coldness 126 1.6 1.6 no signal
555 Feeling Hot 561 1.6 1.6 no signal
556 Blood Triglycerides Increased 162 1.6 1.6 no signal
557 Respiratory Disorder 274 1.6 1.6 no signal
558 Transplant Rejection 73 1.6 1.6 no signal
559 Feeling Cold 254 1.6 1.6 no signal
560 Urinary Retention 303 1.6 1.6 no signal
561 Dizziness 4,526 1.6 1.7 no signal
562 Pollakiuria 378 1.6 1.6 no signal
563 Gastrointestinal Disorder 801 1.6 1.6 no signal
564 Nerve Injury 101 1.6 1.6 no signal
565 Orthostatic Hypotension 158 1.6 1.6 no signal
566 Tooth Disorder 201 1.6 1.6 no signal
567 Metastases To Bone 147 1.6 1.6 no signal
568 Angina Pectoris 258 1.6 1.6 no signal
569 Contusion 858 1.6 1.6 no signal
570 Hypoaesthesia 1,337 1.6 1.6 no signal
571 Hemiparesis 152 1.6 1.6 no signal
572 Abnormal Faeces 73 1.6 1.6 no signal
573 Asthma 998 1.6 1.6 no signal
574 Intestinal Perforation 100 1.6 1.6 no signal
575 Fall 2,957 1.6 1.6 no signal
576 Balance Disorder 769 1.6 1.6 no signal
577 Cyanosis 140 1.6 1.6 no signal
578 Herpes Zoster 511 1.6 1.6 no signal
579 Dialysis 126 1.6 1.6 no signal
580 Head Discomfort 156 1.6 1.6 no signal
581 Madarosis 103 1.6 1.6 no signal
582 Limb Discomfort 272 1.6 1.6 no signal
583 Sleep Disorder Due To A General Medical Condition 142 1.6 1.6 no signal
584 Autoimmune Disorder 84 1.6 1.6 no signal
585 Dysstasia 257 1.6 1.6 no signal
586 Influenza 980 1.6 1.6 no signal
587 Tooth Extraction 109 1.6 1.6 no signal
588 Blood Creatine Phosphokinase Increased 256 1.6 1.6 no signal
589 Metastases To Lung 101 1.6 1.6 no signal
590 Loss Of Personal Independence In Daily Activities 416 1.6 1.6 no signal
591 Scar 150 1.6 1.6 no signal
592 Dysgeusia 653 1.6 1.6 no signal
593 Hot Flush 659 1.6 1.6 no signal
594 Eye Swelling 323 1.6 1.6 no signal
595 Rash Pruritic 471 1.6 1.6 no signal
596 Pulmonary Embolism 830 1.6 1.6 no signal
597 Heart Rate Decreased 306 1.6 1.6 no signal
598 Tremor 1,441 1.6 1.6 no signal
599 Haemorrhage Intracranial 130 1.6 1.6 no signal
600 Blood Urine Present 165 1.6 1.6 no signal
601 Laryngitis 94 1.6 1.6 no signal
602 Hallucination, Visual 181 1.6 1.6 no signal
603 Coordination Abnormal 121 1.6 1.6 no signal
604 Pruritus 3,252 1.5 1.6 no signal
605 Cardio-respiratory Arrest 362 1.5 1.6 no signal
606 Purpura 76 1.5 1.5 no signal
607 Muscle Spasms 1,577 1.5 1.6 no signal
608 Muscle Atrophy 108 1.5 1.5 no signal
609 Therapy Interrupted 592 1.5 1.5 no signal
610 Stress 616 1.5 1.5 no signal
611 Post Procedural Haemorrhage 100 1.5 1.5 no signal
612 Cerebral Haemorrhage 306 1.5 1.5 no signal
613 Disease Progression 1,009 1.5 1.5 no signal
614 Headache 5,357 1.5 1.6 no signal
615 Hypersensitivity 1,585 1.5 1.5 no signal
616 Gait Inability 283 1.5 1.5 no signal
617 Sneezing 191 1.5 1.5 no signal
618 Feeling Jittery 163 1.5 1.5 no signal
619 Fibromyalgia 207 1.5 1.5 no signal
620 Lymphadenopathy 302 1.5 1.5 no signal
621 Plasma Cell Myeloma 332 1.5 1.5 no signal
622 Myositis 76 1.5 1.5 no signal
623 Disorientation 336 1.5 1.5 no signal
624 Chromaturia 191 1.5 1.5 no signal
625 Cytopenia 101 1.5 1.5 no signal
626 Panic Attack 308 1.5 1.5 no signal
627 Fungal Infection 281 1.5 1.5 no signal
628 Gingival Bleeding 115 1.5 1.5 no signal
629 Speech Disorder 439 1.5 1.5 no signal
630 Tinnitus 384 1.5 1.5 no signal
631 Colon Cancer 124 1.5 1.5 no signal
632 Fear 225 1.5 1.5 no signal
633 Jaundice 224 1.5 1.5 no signal
634 Therapy Change 80 1.5 1.5 no signal
635 Melaena 183 1.5 1.5 no signal
636 Lung Disorder 406 1.5 1.5 no signal
637 Cyst 103 1.5 1.5 no signal
638 Confusional State 1,339 1.5 1.5 no signal
639 Rhabdomyolysis 344 1.5 1.5 no signal
640 Skin Discolouration 379 1.5 1.5 no signal
641 Aphonia 115 1.5 1.5 no signal
642 Thrombosis 665 1.5 1.5 no signal
643 Salivary Hypersecretion 82 1.5 1.5 no signal
644 Liver Function Test Increased 175 1.5 1.5 no signal
645 Ageusia 205 1.5 1.5 no signal
646 Blister 459 1.5 1.5 no signal
647 Arthralgia 3,390 1.5 1.5 no signal
648 Cytomegalovirus Infection 136 1.5 1.5 no signal
649 Night Sweats 263 1.5 1.5 no signal
650 Pancreatitis 430 1.5 1.5 no signal
651 Nasopharyngitis 1,500 1.5 1.5 no signal
652 Burning Sensation 568 1.5 1.5 no signal
653 Pain In Extremity 2,387 1.5 1.5 no signal
654 Poor Quality Sleep 173 1.5 1.5 no signal
655 Infection 1,165 1.5 1.5 no signal
656 Skin Disorder 268 1.4 1.5 no signal
657 Insomnia 2,148 1.4 1.5 no signal
658 Hallucination 603 1.4 1.5 no signal
659 Hepatic Failure 243 1.4 1.4 no signal
660 Diabetes Mellitus 614 1.4 1.4 no signal
661 Lower Limb Fracture 153 1.4 1.4 no signal
662 Wound Infection 87 1.4 1.4 no signal
663 Myalgia 1,360 1.4 1.4 no signal
664 Cataract 474 1.4 1.4 no signal
665 Discomfort 483 1.4 1.4 no signal
666 Hyperhidrosis 1,027 1.4 1.4 no signal
667 Product Use In Unapproved Indication 1,944 1.4 1.4 no signal
668 Cardiac Arrest 657 1.4 1.4 no signal
669 Pain 4,875 1.4 1.4 no signal
670 Bradycardia 421 1.4 1.4 no signal
671 Disease Recurrence 378 1.4 1.4 no signal
672 Dysarthria 298 1.4 1.4 no signal
673 Therapy Non-responder 353 1.4 1.4 no signal
674 Sleep Disorder 553 1.4 1.4 no signal
675 Bronchospasm 113 1.4 1.4 no signal
676 Rash 3,416 1.4 1.4 no signal
677 Depressed Level Of Consciousness 311 1.4 1.4 no signal
678 Gastric Disorder 274 1.4 1.4 no signal
679 Rash Macular 274 1.4 1.4 no signal
680 Metabolic Acidosis 249 1.4 1.4 no signal
681 Syncope 787 1.4 1.4 no signal
682 Appendicitis 73 1.4 1.4 no signal
683 Electrocardiogram Qt Prolonged 282 1.4 1.4 no signal
684 Haematoma 203 1.4 1.4 no signal
685 Blood Count Abnormal 120 1.4 1.4 no signal
686 Serotonin Syndrome 149 1.4 1.4 no signal
687 Metastases To Central Nervous System 99 1.4 1.4 no signal
688 Surgery 447 1.4 1.4 no signal
689 Spinal Pain 90 1.4 1.4 no signal
690 Blood Cholesterol Increased 358 1.4 1.4 no signal
691 Bone Density Decreased 243 1.4 1.4 no signal
692 Type 2 Diabetes Mellitus 259 1.4 1.4 no signal
693 Oral Herpes 149 1.4 1.4 no signal
694 Leukaemia 72 1.4 1.4 no signal
695 Emotional Distress 927 1.4 1.4 no signal
696 Osteonecrosis Of Jaw 190 1.4 1.4 no signal
697 Choking 148 1.4 1.4 no signal
698 Gait Disturbance 1,462 1.4 1.4 no signal
699 Dementia 212 1.4 1.4 no signal
700 Unevaluable Event 576 1.4 1.4 no signal
701 Abscess 121 1.4 1.4 no signal
702 Aphasia 229 1.4 1.4 no signal
703 Delusion 117 1.4 1.4 no signal
704 Eye Irritation 420 1.4 1.4 no signal
705 Skin Lesion 205 1.4 1.4 no signal
706 Impaired Healing 247 1.4 1.4 no signal
707 Joint Dislocation 79 1.3 1.3 no signal
708 Paraesthesia 1,182 1.3 1.4 no signal
709 Dermatitis 155 1.3 1.3 no signal
710 Eye Pruritus 246 1.3 1.3 no signal
711 Neutropenia 1,010 1.3 1.3 no signal
712 Seizure 855 1.3 1.3 no signal
713 Musculoskeletal Pain 393 1.3 1.3 no signal
714 Haematochezia 410 1.3 1.3 no signal
715 Skin Haemorrhage 107 1.3 1.3 no signal
716 Wound 206 1.3 1.3 no signal
717 Sluggishness 75 1.3 1.3 no signal
718 Hepatic Cirrhosis 138 1.3 1.3 no signal
719 Vision Blurred 1,007 1.3 1.3 no signal
720 Cardiac Failure 592 1.3 1.3 no signal
721 Cold Sweat 130 1.3 1.3 no signal
722 Laceration 70 1.3 1.3 no signal
723 Device Occlusion 102 1.3 1.3 no signal
724 Pulmonary Fibrosis 140 1.3 1.3 no signal
725 Mouth Ulceration 154 1.3 1.3 no signal
726 Pneumocystis Jirovecii Pneumonia 73 1.3 1.3 no signal
727 Ataxia 87 1.3 1.3 no signal
728 Cardiogenic Shock 104 1.3 1.3 no signal
729 Tendonitis 113 1.3 1.3 no signal
730 Deformity 68 1.3 1.3 no signal
731 Liver Function Test Abnormal 212 1.3 1.3 no signal
732 Hepatic Enzyme Increased 492 1.3 1.3 no signal
733 Paralysis 104 1.3 1.3 no signal
734 Restlessness 265 1.3 1.3 no signal
735 Squamous Cell Carcinoma 68 1.3 1.3 no signal
736 Foot Deformity 80 1.3 1.3 no signal
737 Skin Fissures 136 1.3 1.3 no signal
738 Somnolence 1,437 1.3 1.3 no signal
739 Scratch 74 1.3 1.3 no signal
740 Feeling Abnormal 1,718 1.3 1.3 no signal
741 Conjunctivitis 131 1.3 1.3 no signal
742 Ejection Fraction Decreased 111 1.3 1.3 no signal
743 Vertigo 434 1.3 1.3 no signal
744 Basal Cell Carcinoma 111 1.3 1.3 no signal
745 Obstructive Airways Disorder 79 1.3 1.3 no signal
746 Drug Level Increased 117 1.3 1.3 no signal
747 Glaucoma 136 1.3 1.3 no signal
748 Condition Aggravated 2,129 1.3 1.3 no signal
749 Nodule 92 1.3 1.3 no signal
750 Tooth Loss 147 1.3 1.3 no signal
751 Alopecia 1,379 1.3 1.3 no signal
752 Diplopia 182 1.3 1.3 no signal
753 Loss Of Consciousness 897 1.3 1.3 no signal
754 Photosensitivity Reaction 115 1.3 1.3 no signal
755 Malignant Neoplasm Progression 711 1.3 1.3 no signal
756 Macular Degeneration 83 1.3 1.3 no signal
757 Rash Erythematous 326 1.3 1.3 no signal
758 Erythema 1,427 1.2 1.3 no signal
759 Amnesia 454 1.2 1.3 no signal
760 Inability To Afford Medication 68 1.2 1.2 no signal
761 Dyskinesia 280 1.2 1.2 no signal
762 Pharyngeal Oedema 107 1.2 1.2 no signal
763 Therapy Cessation 350 1.2 1.2 no signal
764 Inappropriate Schedule Of Product Administration 1,211 1.2 1.2 no signal
765 Leukopenia 340 1.2 1.2 no signal
766 Acute Myeloid Leukaemia 106 1.2 1.2 no signal
767 Respiratory Arrest 189 1.2 1.2 no signal
768 Deafness 178 1.2 1.2 no signal
769 Drug Interaction 1,077 1.2 1.2 no signal
770 Memory Impairment 929 1.2 1.2 no signal
771 Drug-induced Liver Injury 208 1.2 1.2 no signal
772 Gastric Haemorrhage 78 1.2 1.2 no signal
773 Thrombotic Microangiopathy 65 1.2 1.2 no signal
774 Femur Fracture 208 1.2 1.2 no signal
775 Weight Increased 1,490 1.2 1.2 no signal
776 Joint Stiffness 175 1.2 1.2 no signal
777 Increased Appetite 125 1.2 1.2 no signal
778 Brain Neoplasm 61 1.2 1.2 no signal
779 Bedridden 87 1.2 1.2 no signal
780 Ocular Hyperaemia 309 1.2 1.2 no signal
781 Immune System Disorder 87 1.2 1.2 no signal
782 Malaise 2,899 1.2 1.2 no signal
783 Upper Limb Fracture 132 1.2 1.2 no signal
784 Joint Range Of Motion Decreased 88 1.2 1.2 no signal
785 Cognitive Disorder 306 1.2 1.2 no signal
786 Prescribed Underdose 131 1.2 1.2 no signal
787 Cardiac Disorder 615 1.2 1.2 no signal
788 Procedural Pain 181 1.2 1.2 no signal
789 Off Label Use 5,672 1.2 1.2 no signal
790 Eczema 328 1.2 1.2 no signal
791 Accidental Overdose 238 1.2 1.2 no signal
792 Dermatitis Allergic 81 1.2 1.2 no signal
793 Road Traffic Accident 272 1.2 1.2 no signal
794 Red Blood Cell Sedimentation Rate Increased 72 1.2 1.2 no signal
795 Pallor 177 1.2 1.2 no signal
796 Product Availability Issue 145 1.2 1.2 no signal
797 Myoclonus 77 1.2 1.2 no signal
798 Nervousness 339 1.2 1.2 no signal
799 Scab 73 1.2 1.2 no signal
800 Agranulocytosis 119 1.2 1.2 no signal
801 Renal Pain 68 1.2 1.2 no signal
802 Knee Arthroplasty 134 1.2 1.2 no signal
803 Coeliac Disease 63 1.2 1.2 no signal
804 Rash Papular 144 1.2 1.2 no signal
805 Depressed Mood 337 1.2 1.2 no signal
806 Hospitalisation 975 1.1 1.2 no signal
807 Lymphopenia 90 1.1 1.1 no signal
808 Hunger 86 1.1 1.1 no signal
809 Arrhythmia 304 1.1 1.1 no signal
810 Hypoglycaemia 310 1.1 1.1 no signal
811 Convulsion 370 1.1 1.1 no signal
812 Breast Pain 68 1.1 1.1 no signal
813 Gastric Cancer 163 1.1 1.1 no signal
814 Product Packaging Issue 59 1.1 1.1 no signal
815 Acute Hepatic Failure 86 1.1 1.1 no signal
816 Intentional Product Use Issue 555 1.1 1.1 no signal
817 Mental Disorder 275 1.1 1.1 no signal
818 Glossodynia 141 1.1 1.1 no signal
819 Myelodysplastic Syndrome 91 1.1 1.1 no signal
820 Disability 124 1.1 1.1 no signal
821 Transaminases Increased 139 1.1 1.1 no signal
822 Adverse Reaction 83 1.1 1.1 no signal
823 Joint Swelling 747 1.1 1.1 no signal
824 Hip Arthroplasty 94 1.1 1.1 no signal
825 Peritonitis 128 1.1 1.1 no signal
826 Vasculitis 72 1.1 1.1 no signal
827 Neoplasm 71 1.1 1.1 no signal
828 Neoplasm Progression 216 1.1 1.1 no signal
829 Abdominal Pain Lower 155 1.1 1.1 no signal
830 Agitation 450 1.1 1.1 no signal
831 Rash Maculo-papular 135 1.1 1.1 no signal
832 Mobility Decreased 435 1.1 1.1 no signal
833 Prostatic Specific Antigen Increased 84 1.1 1.1 no signal
834 Inflammation 311 1.1 1.1 no signal
835 Muscle Twitching 140 1.1 1.1 no signal
836 Drug Hypersensitivity 1,171 1.1 1.1 no signal
837 Neurotoxicity 104 1.1 1.1 no signal
838 Ovarian Cyst 60 1.1 1.1 no signal
839 Injection Site Rash 181 1.1 1.1 no signal
840 Treatment Noncompliance 324 1.1 1.1 no signal
841 Bone Marrow Failure 122 1.1 1.1 no signal
842 Product Administration Error 119 1.1 1.1 no signal
843 Fistula 67 1.1 1.1 no signal
844 Pelvic Pain 108 1.1 1.1 no signal
845 Musculoskeletal Stiffness 520 1.1 1.1 no signal
846 Fracture 112 1.1 1.1 no signal
847 Frequent Bowel Movements 159 1.1 1.1 no signal
848 Skin Exfoliation 491 1.1 1.1 no signal
849 Eyelid Ptosis 60 1.1 1.1 no signal
850 Cerebrovascular Accident 1,001 1.1 1.1 no signal
851 Product Taste Abnormal 79 1.1 1.1 no signal
852 Knee Operation 57 1.1 1.1 no signal
853 Drug Ineffective For Unapproved Indication 327 1.1 1.1 no signal
854 Arthropathy 327 1.1 1.1 no signal
855 Lactic Acidosis 188 1.1 1.1 no signal
856 Parkinsonism 57 1.0 1.0 no signal
857 Prescribed Overdose 113 1.0 1.0 no signal
858 Diabetes Mellitus Inadequate Control 103 1.0 1.0 no signal
859 Glycosylated Haemoglobin Increased 146 1.0 1.0 no signal
860 Blood Glucose Decreased 279 1.0 1.0 no signal
861 Product Use Issue 1,082 1.0 1.0 no signal
862 Rash Generalised 152 1.0 1.0 no signal
863 Haemorrhage 604 1.0 1.0 no signal
864 Emotional Disorder 179 1.0 1.0 no signal
865 Multiple Organ Dysfunction Syndrome 161 1.0 1.0 no signal
866 Diarrhoea Haemorrhagic 54 1.0 1.0 no signal
867 Thinking Abnormal 108 1.0 1.0 no signal
868 Crying 210 1.0 1.0 no signal
869 Hyperthyroidism 83 1.0 1.0 no signal
870 Tendon Rupture 71 1.0 1.0 no signal
871 Bone Loss 87 1.0 1.0 no signal
872 Incorrect Route Of Product Administration 96 1.0 1.0 no signal
873 Irritability 344 1.0 1.0 no signal
874 Influenza Like Illness 472 1.0 1.0 no signal
875 Hypoacusis 244 1.0 1.0 no signal
876 Drug Toxicity 78 1.0 1.0 no signal
877 Expired Product Administered 187 1.0 1.0 no signal
878 Therapeutic Response Decreased 339 1.0 1.0 no signal
879 Exposure Via Skin Contact 127 1.0 1.0 no signal
880 Incorrect Drug Administration Duration 160 1.0 1.0 no signal
881 Dry Skin 734 1.0 1.0 no signal
882 Therapy Partial Responder 84 1.0 1.0 no signal
883 Hypokinesia 81 1.0 1.0 no signal
884 Rebound Effect 63 1.0 1.0 no signal
885 Product Prescribing Issue 113 1.0 1.0 no signal
886 Lymphoma 86 1.0 1.0 no signal
887 Sedation 144 1.0 1.0 no signal
888 Eye Disorder 181 1.0 1.0 no signal
889 Breast Cancer Metastatic 59 1.0 1.0 no signal
890 Local Swelling 97 1.0 1.0 no signal
891 Injection Site Swelling 415 1.0 1.0 no signal
892 Blindness Unilateral 77 1.0 1.0 no signal
893 Mood Altered 148 1.0 1.0 no signal
894 Grand Mal Convulsion 51 1.0 1.0 no signal
895 Eosinophilia 95 1.0 1.0 no signal
896 Movement Disorder 175 1.0 1.0 no signal
897 Hypothermia 55 1.0 1.0 no signal
898 Nightmare 188 1.0 1.0 no signal
899 Contraindicated Product Administered 163 1.0 1.0 no signal
900 Adverse Drug Reaction 480 1.0 1.0 no signal
901 Therapeutic Product Effect Incomplete 376 1.0 1.0 no signal
902 Disturbance In Attention 287 1.0 1.0 no signal
903 Muscle Rigidity 63 0.9 0.9 no signal
904 Myocardial Infarction 926 0.9 0.9 no signal
905 Paranoia 91 0.9 0.9 no signal
906 Drug Intolerance 505 0.9 0.9 no signal
907 Dermatitis Atopic 262 0.9 0.9 no signal
908 Activities Of Daily Living Impaired 105 0.9 0.9 no signal
909 Therapeutic Response Shortened 166 0.9 0.9 no signal
910 Visual Impairment 641 0.9 0.9 no signal
911 Product Odour Abnormal 54 0.9 0.9 no signal
912 Helicobacter Infection 53 0.9 0.9 no signal
913 Skin Cancer 112 0.9 0.9 no signal
914 Pruritus Generalised 114 0.9 0.9 no signal
915 Skin Reaction 73 0.9 0.9 no signal
916 Diabetic Ketoacidosis 124 0.9 0.9 no signal
917 Musculoskeletal Disorder 99 0.9 0.9 no signal
918 Eye Haemorrhage 69 0.9 0.9 no signal
919 Product Physical Issue 102 0.9 0.9 no signal
920 Osteonecrosis 169 0.9 0.9 no signal
921 Injection Site Reaction 349 0.9 0.9 no signal
922 Impaired Work Ability 109 0.9 0.9 no signal
923 Brain Injury 51 0.9 0.9 no signal
924 Central Nervous System Lesion 70 0.9 0.9 no signal
925 Injection Site Pruritus 336 0.9 0.9 no signal
926 Accident 60 0.9 0.9 no signal
927 Status Epilepticus 57 0.9 0.9 no signal
928 Device Failure 76 0.9 0.9 no signal
929 Ill-defined Disorder 303 0.9 0.9 no signal
930 Drug Ineffective 6,551 0.9 0.9 no signal
931 Sensory Disturbance 80 0.9 0.9 no signal
932 Injection Site Induration 64 0.9 0.9 no signal
933 Muscle Spasticity 61 0.9 0.9 no signal
934 Hallucination, Auditory 78 0.9 0.9 no signal
935 Abnormal Dreams 136 0.9 0.9 no signal
936 Sudden Death 52 0.9 0.9 no signal
937 Injection Site Discolouration 60 0.9 0.9 no signal
938 Nervous System Disorder 151 0.9 0.9 no signal
939 Neoplasm Malignant 321 0.9 0.9 no signal
940 Abnormal Behaviour 191 0.9 0.9 no signal
941 Ovarian Cancer 44 0.9 0.9 no signal
942 Sickle Cell Anaemia With Crisis 75 0.9 0.9 no signal
943 Motor Dysfunction 48 0.9 0.9 no signal
944 Mental Impairment 115 0.8 0.8 no signal
945 Hepatitis 121 0.8 0.8 no signal
946 Generalised Tonic-clonic Seizure 77 0.8 0.8 no signal
947 Injection Site Urticaria 114 0.8 0.8 no signal
948 Therapeutic Product Effect Decreased 207 0.8 0.8 no signal
949 Impaired Driving Ability 53 0.8 0.8 no signal
950 Rheumatoid Arthritis 526 0.8 0.8 no signal
951 General Physical Health Deterioration 533 0.8 0.8 no signal
952 Incorrect Dose Administered 1,039 0.8 0.8 no signal
953 Hepatitis C 56 0.8 0.8 no signal
954 Nephropathy Toxic 51 0.8 0.8 no signal
955 Injection Site Bruising 361 0.8 0.8 no signal
956 Lung Infection 72 0.8 0.8 no signal
957 Retinal Detachment 42 0.8 0.8 no signal
958 Toxic Skin Eruption 46 0.8 0.8 no signal
959 Needle Issue 130 0.8 0.8 no signal
960 Blood Glucose Increased 856 0.8 0.8 no signal
961 Death 3,897 0.8 0.8 no signal
962 No Adverse Event 794 0.8 0.8 no signal
963 Injection Site Erythema 551 0.8 0.8 no signal
964 Product Prescribing Error 105 0.8 0.8 no signal
965 Cardiovascular Disorder 113 0.8 0.8 no signal
966 Malignant Melanoma 59 0.8 0.8 no signal
967 Suicidal Ideation 402 0.8 0.8 no signal
968 Psoriatic Arthropathy 174 0.8 0.8 no signal
969 Systemic Lupus Erythematosus 152 0.8 0.8 no signal
970 Mydriasis 55 0.8 0.8 no signal
971 Hypotonia 43 0.8 0.8 no signal
972 Injection Site Irritation 54 0.8 0.8 no signal
973 Mania 70 0.8 0.8 no signal
974 Product Dose Omission 280 0.8 0.8 no signal
975 Multiple Sclerosis 203 0.8 0.8 no signal
976 Posterior Reversible Encephalopathy Syndrome 40 0.8 0.8 no signal
977 Blood Glucose Abnormal 77 0.7 0.7 no signal
978 Product Substitution Issue 239 0.7 0.7 no signal
979 Extra Dose Administered 165 0.7 0.7 no signal
980 Neuroleptic Malignant Syndrome 49 0.7 0.7 no signal
981 Abasia 103 0.7 0.7 no signal
982 Adverse Event 377 0.7 0.7 no signal
983 Medication Error 227 0.7 0.7 no signal
984 Drug Reaction With Eosinophilia And Systemic Symptoms 104 0.7 0.7 no signal
985 Inflammatory Bowel Disease 40 0.7 0.7 no signal
986 Myocarditis 46 0.7 0.7 no signal
987 Device Dislocation 176 0.7 0.7 no signal
988 Product Dispensing Error 88 0.7 0.7 no signal
989 Pain Of Skin 109 0.7 0.7 no signal
990 Circulatory Collapse 69 0.7 0.7 no signal
991 Blindness 164 0.7 0.7 no signal
992 Aggression 202 0.7 0.7 no signal
993 Drug Level Decreased 41 0.7 0.7 no signal
994 Apathy 58 0.7 0.7 no signal
995 Decreased Immune Responsiveness 39 0.7 0.7 no signal
996 No Therapeutic Response 49 0.7 0.7 no signal
997 Anger 134 0.7 0.7 no signal
998 Eyelid Oedema 46 0.7 0.7 no signal
999 Multiple Sclerosis Relapse 271 0.7 0.7 no signal
1000 Intentional Product Misuse 338 0.7 0.7 no signal
1001 Wrong Technique In Product Usage Process 782 0.7 0.7 no signal
1002 Affect Lability 37 0.7 0.7 no signal
1003 Eye Inflammation 36 0.7 0.7 no signal
1004 Underdose 277 0.7 0.7 no signal
1005 Polyneuropathy 45 0.7 0.7 no signal
1006 Injection Site Discomfort 39 0.7 0.7 no signal
1007 Folliculitis 39 0.7 0.7 no signal
1008 Injection Site Pain 1,145 0.7 0.7 no signal
1009 Injection Site Extravasation 47 0.7 0.7 no signal
1010 Mood Swings 120 0.7 0.7 no signal
1011 Pancreatic Carcinoma 109 0.7 0.7 no signal
1012 Blood Glucose Fluctuation 41 0.7 0.7 no signal
1013 Visual Acuity Reduced 124 0.7 0.7 no signal
1014 Dystonia 72 0.7 0.7 no signal
1015 Tardive Dyskinesia 105 0.7 0.7 no signal
1016 Device Issue 321 0.7 0.7 no signal
1017 Device Defective 59 0.7 0.7 no signal
1018 Injection Site Warmth 75 0.7 0.7 no signal
1019 Psychotic Disorder 107 0.6 0.6 no signal
1020 Poor Quality Product Administered 37 0.6 0.6 no signal
1021 Akathisia 49 0.6 0.6 no signal
1022 Ischaemic Stroke 64 0.6 0.6 no signal
1023 Maternal Exposure During Pregnancy 315 0.6 0.6 no signal
1024 Personality Change 33 0.6 0.6 no signal
1025 Colitis Ulcerative 157 0.6 0.6 no signal
1026 Lung Neoplasm Malignant 145 0.6 0.6 no signal
1027 Respiratory Depression 43 0.6 0.6 no signal
1028 Intraocular Pressure Increased 45 0.6 0.6 no signal
1029 Uveitis 47 0.6 0.6 no signal
1030 Psychomotor Hyperactivity 58 0.6 0.6 no signal
1031 Liver Injury 84 0.6 0.6 no signal
1032 Injection Site Nodule 38 0.6 0.6 no signal
1033 Erectile Dysfunction 89 0.6 0.6 no signal
1034 Epilepsy 105 0.6 0.6 no signal
1035 Pericarditis 57 0.6 0.6 no signal
1036 Cholestasis 65 0.6 0.6 no signal
1037 Euphoric Mood 35 0.6 0.6 no signal
1038 Libido Decreased 42 0.6 0.6 no signal
1039 Vaginal Discharge 34 0.6 0.6 no signal
1040 Anosmia 49 0.6 0.6 no signal
1041 Coma 161 0.6 0.6 no signal
1042 Lower Respiratory Tract Infection 153 0.6 0.6 no signal
1043 Premature Delivery 54 0.6 0.6 no signal
1044 Device Malfunction 224 0.6 0.6 no signal
1045 Ankylosing Spondylitis 43 0.6 0.6 no signal
1046 Device Leakage 138 0.6 0.6 no signal
1047 Injection Site Mass 119 0.6 0.6 no signal
1048 Vaginal Haemorrhage 137 0.6 0.6 no signal
1049 Product Packaging Quantity Issue 35 0.6 0.6 no signal
1050 Drug Effect Decreased 175 0.6 0.6 no signal
1051 Skeletal Injury 33 0.6 0.6 no signal
1052 Wrong Technique In Drug Usage Process 115 0.6 0.6 no signal
1053 Drug Administration Error 96 0.6 0.6 no signal
1054 Psoriasis 401 0.5 0.5 no signal
1055 Device Use Issue 53 0.5 0.5 no signal
1056 Withdrawal Syndrome 128 0.5 0.5 no signal
1057 Pharmaceutical Product Complaint 78 0.5 0.5 no signal
1058 Drug Dose Omission 495 0.5 0.5 no signal
1059 Product Quality Issue 397 0.5 0.5 no signal
1060 Hepatotoxicity 65 0.5 0.5 no signal
1061 Sexual Dysfunction 34 0.5 0.5 no signal
1062 Thyroid Cancer 35 0.5 0.5 no signal
1063 Skin Burning Sensation 204 0.5 0.5 no signal
1064 Overdose 617 0.5 0.5 no signal
1065 Injection Site Haemorrhage 222 0.5 0.5 no signal
1066 Extrapyramidal Disorder 70 0.5 0.5 no signal
1067 Drug Effect Incomplete 102 0.5 0.5 no signal
1068 Syringe Issue 48 0.5 0.5 no signal
1069 Intentional Drug Misuse 58 0.5 0.5 no signal
1070 Inappropriate Schedule Of Drug Administration 197 0.5 0.5 no signal
1071 Acne 207 0.5 0.5 no signal
1072 Renal Cancer 130 0.5 0.5 no signal
1073 Dysmenorrhoea 35 0.5 0.5 no signal
1074 Unintentional Medical Device Removal 31 0.5 0.5 no signal
1075 Synovitis 47 0.5 0.5 no signal
1076 Toxicity To Various Agents 435 0.5 0.5 no signal
1077 Peritonitis Bacterial 26 0.5 0.5 no signal
1078 Abortion Spontaneous 103 0.5 0.5 no signal
1079 Product Preparation Error 53 0.5 0.5 no signal
1080 Accidental Exposure To Product 251 0.4 0.4 no signal
1081 Menorrhagia 49 0.4 0.4 no signal
1082 Poisoning 31 0.4 0.4 no signal
1083 Amenorrhoea 41 0.4 0.4 no signal
1084 Application Site Pain 54 0.4 0.4 no signal
1085 Skin Irritation 111 0.4 0.4 no signal
1086 Caesarean Section 28 0.4 0.4 no signal
1087 Device Delivery System Issue 62 0.4 0.4 no signal
1088 Suicide Attempt 144 0.4 0.4 no signal
1089 Product Complaint 58 0.4 0.4 no signal
1090 Schizophrenia 28 0.4 0.4 no signal
1091 Completed Suicide 193 0.4 0.4 no signal
1092 Hypertensive Crisis 25 0.4 0.4 no signal
1093 Breast Cancer Female 60 0.4 0.4 no signal
1094 Device Use Error 75 0.4 0.4 no signal
1095 Drug Dispensing Error 34 0.4 0.4 no signal
1096 Circumstance Or Information Capable Of Leading To Medication Error 72 0.4 0.4 no signal
1097 Prostate Cancer 173 0.4 0.4 no signal
1098 Drug Effective For Unapproved Indication 62 0.4 0.4 no signal
1099 Application Site Pruritus 48 0.4 0.4 no signal
1100 Device Breakage 82 0.4 0.4 no signal
1101 Hepatic Cancer 50 0.4 0.4 no signal
1102 Premature Baby 62 0.4 0.4 no signal
1103 Product Administered At Inappropriate Site 37 0.4 0.4 no signal
1104 Treatment Failure 166 0.4 0.4 no signal
1105 Product Storage Error 174 0.4 0.4 no signal
1106 Application Site Irritation 25 0.4 0.4 no signal
1107 Breast Cancer 188 0.4 0.4 no signal
1108 Pregnancy 40 0.4 0.4 no signal
1109 Drug Prescribing Error 38 0.3 0.3 no signal
1110 Tuberculosis 25 0.3 0.3 no signal
1111 Complication Of Device Insertion 36 0.3 0.3 no signal
1112 Embedded Device 19 0.3 0.3 no signal
1113 Bladder Cancer 114 0.3 0.3 no signal
1114 Application Site Rash 26 0.3 0.3 no signal
1115 Oesophageal Carcinoma 55 0.3 0.3 no signal
1116 Wrong Technique In Device Usage Process 81 0.3 0.3 no signal
1117 Drug Withdrawal Syndrome 157 0.3 0.3 no signal
1118 Application Site Erythema 46 0.3 0.3 no signal
1119 Drug Exposure During Pregnancy 59 0.3 0.3 no signal
1120 Incorrect Product Storage 22 0.3 0.3 no signal
1121 Injection Site Haematoma 23 0.3 0.3 no signal
1122 Foetal Exposure During Pregnancy 126 0.3 0.3 no signal
1123 Incorrect Dose Administered By Device 38 0.3 0.3 no signal
1124 Product Adhesion Issue 51 0.3 0.3 no signal
1125 Hand Deformity 18 0.2 0.2 no signal
1126 Myelosuppression 46 0.2 0.2 no signal
1127 Device Difficult To Use 87 0.2 0.2 no signal
1128 Complication Of Device Removal 22 0.2 0.2 no signal
1129 Abnormal Weight Gain 16 0.2 0.2 no signal
1130 Device Deployment Issue 15 0.2 0.2 no signal
1131 Drug Resistance 32 0.2 0.2 no signal
1132 Menstruation Irregular 33 0.2 0.2 no signal
1133 Hepatocellular Injury 17 0.2 0.2 no signal
1134 Gynaecomastia 37 0.2 0.2 no signal
1135 Accidental Underdose 17 0.2 0.2 no signal
1136 Meningioma 17 0.2 0.2 no signal
1137 Incorrect Route Of Drug Administration 41 0.2 0.2 no signal
1138 Intentional Overdose 69 0.2 0.2 no signal
1139 Drug Dose Omission By Device 77 0.2 0.2 no signal
1140 Injury Associated With Device 20 0.2 0.2 no signal
1141 Colorectal Cancer 48 0.2 0.2 no signal
1142 Intentional Self-injury 20 0.2 0.2 no signal
1143 Gastrointestinal Carcinoma 9 0.2 0.2 no signal
1144 Haematotoxicity 9 0.2 0.2 no signal
1145 Abortion Induced 9 0.2 0.2 no signal
1146 Genital Haemorrhage 12 0.2 0.2 no signal
1147 Drug Dependence 149 0.2 0.2 no signal
1148 Device Adhesion Issue 13 0.2 0.2 no signal
1149 Device Mechanical Issue 11 0.2 0.2 no signal
1150 Menstruation Delayed 8 0.1 0.1 no signal
1151 Metrorrhagia 13 0.1 0.1 no signal
1152 Drug Abuse 62 0.1 0.1 no signal
1153 Breast Cancer Stage I 5 0.1 0.1 no signal
1154 Device Expulsion 32 0.1 0.1 no signal
1155 Drug Administered At Inappropriate Site 5 0.1 0.1 no signal
1156 Pemphigus 5 0.1 0.1 no signal
1157 Drug Withdrawal Syndrome Neonatal 6 0.1 0.1 no signal
1158 Unintended Pregnancy 3 0.1 0.1 no signal
1159 Dependence 15 0.0 0.0 no signal