Reaction

Peptic Ulcer reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,278 reports · 125 co-occurring drugs

As of the last recalculation, Peptic Ulcer appears in 3,278 FAERS reports alongside 125 co-occurring drug terms. The strongest observed disproportionality signal is OLMESARTAN MEDOXOMIL (PRR 35.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Olmesartan Medoxomil	187	35.0	35.1
Sucralfate	82	22.3	22.3
Sucralfate Oral	45	20.4	20.4
Sucralfate Oral Suspension	45	20.3	20.4
Alendronate Sodium	250	16.9	17.0
Cimetidine	25	16.6	16.6
Efavirenz	18	10.3	10.3
Loperamide Hydrochloride Oral	15	9.4	9.4
Diclofenac Sodium 1%	49	8.8	8.8
Diclofenac Sodium Topical	49	8.8	8.8
Diclofenac Sodium Topical Gel, 1%	49	8.8	8.8
Ibuprofen Oral	256	8.8	8.8
Ibuprofen Capsule	255	8.7	8.7
Ibuprofen Tablet, Film Coated	255	8.7	8.7
Ibupfrofen	255	8.7	8.7
Ibuprofen Tablets Usp, 200Mg	255	8.7	8.7
Ibuprofen Capsules 200 Mg	255	8.7	8.7
Ibuprofen 200 Mg	255	8.7	8.7
Ibuprofen 200Mg	255	8.7	8.7
Meperidine Hydrochloride	12	8.3	8.3
Amlodipine Besylate And Benazepril Hydrochloride	12	8.3	8.3
Rabeprazole Sodium	35	8.2	8.2
Methylprednisolone Acetate	10	8.0	8.0
Loperamide Hcl	16	7.9	7.9
Hydroxyzine Hydrochloride	16	7.8	7.8
Hydroxyzine Hydrochloride Oral	16	7.8	7.8
Diclofenac	101	7.6	7.7
Ciclesonide	16	7.5	7.5
Ibuprofen	293	7.4	7.4
Metoclopramide	63	7.4	7.4
Isosorbide Mononitrate	24	7.4	7.4
Gemfibrozil	17	7.1	7.2
Metoclopramide Hydrochloride	83	7.0	7.0
Cefazolin	10	7.0	7.0
Hyoscyamine Sulfate	10	6.9	6.9
Conjugated Estrogens	62	6.9	6.9
Lutetium Lu 177 Vipivotide Tetraxetan	14	6.8	6.8
Estrogens, Conjugated	62	6.7	6.7
Nitroglycerin	55	6.6	6.6
Standardized Senna Concentrate	13	6.6	6.6
Meclizine Hcl 12.5Mg	14	6.5	6.6
Meclizine Hcl 25Mg	14	6.5	6.6
Meclizine Hcl 12.5 Mg	14	6.5	6.5
Meclizine Hcl 25 Mg	14	6.5	6.5
Meloxicam	58	6.4	6.4
Carisoprodol	19	6.4	6.4
Cefazolin Sodium	12	6.3	6.3
Vitamin E	31	6.3	6.3
Prasugrel Hydrochloride	10	6.3	6.3
Meclizine	16	6.2	6.3
Theophylline Anhydrous	12	6.2	6.2
Diltiazem Hydrochloride	33	6.1	6.1
Theophylline	11	6.1	6.1
Nystatin Ointment	25	6.1	6.1
Nystatin Cream	25	6.1	6.1
Pantoprazole Sodium	136	6.0	6.0
Erlotinib	9	5.9	5.9
Calcium, Magnesium, Potassium, And Sodium Oxybates	8	5.9	5.9
Nystatin	25	5.8	5.8
Glyburide	22	5.8	5.8
Naproxen	70	5.8	5.8
Digoxin	64	5.8	5.8
Diclofenac Sodium	130	5.7	5.7
Enalapril Maleate	22	5.7	5.7
Temazepam	33	5.6	5.6
Candesartan Cilexetil	23	5.6	5.6
Meclizine Hydrochloride	17	5.5	5.5
Esomeprazole Magnesium	193	5.5	5.5
Ibuprofen And Diphenhydramine Citrate	20	5.5	5.5
Leflunomide	88	5.5	5.5
Famotidine	97	5.4	5.4
Ketoprofen	11	5.3	5.3
Trazodone Hydrochloride	13	5.3	5.3
Misoprostol	8	5.2	5.2
Erlotinib Hydrochloride	10	5.1	5.1
Naproxen Sodium	110	5.0	5.0
Potassium Chloride, Dextrose Monohydrate	71	5.0	5.0
Potassium Chloride Oral	71	5.0	5.0
Potassium Chloride Extended-Release	71	5.0	5.0
Potassium Chloride	86	4.9	4.9
Epoetin Alfa	9	4.8	4.8
Dextrose	10	4.8	4.8
Hydrochlorothiazide	107	4.8	4.8
Oseltamivir	6	4.8	4.8
Dextrose Monohydrate	10	4.8	4.8
Fondaparinux Sodium	6	4.7	4.7
Ezetimibe And Simvastatin	11	4.6	4.6
Ferrous Sulfate	36	4.6	4.6
Isotretinoin	35	4.5	4.5
Sulfasalazine	55	4.5	4.5
Lansoprazole	123	4.5	4.5
Vortioxetine	12	4.5	4.5
Clopidogrel	129	4.3	4.3
Nicotine Polacrilex Mini	10	4.2	4.2
Nicotine Polarilex	10	4.2	4.2
Heparin Sodium	9	4.2	4.2
Acetaminophen, Aspirin (Nsaid) And Caffeine	11	4.1	4.1
Tamsulosin Hydrochloride	13	4.1	4.1
Cefepime	9	4.0	4.0
Naproxen Sodium Tablet	33	4.0	4.0
Lovastatin	16	4.0	4.0
Acetaminophen, Aspirin, And Caffeine	13	3.9	3.9
Raloxifene Hydrochloride	9	3.9	3.9
Sitagliptin	44	3.9	3.9
Benzonatate	10	3.9	3.9
Donepezil Hydrochloride	21	3.7	3.7
Apixaban	38	3.6	3.6
Tapentadol Hydrochloride	19	3.6	3.6
Dabigatran Etexilate	42	3.5	3.5
Amlodipine Besylate And Valsartan	6	3.4	3.4
Polatuzumab Vedotin	5	3.3	3.3
Oseltamivir Phosphate	12	3.1	3.1
Dexlansoprazole	20	3.1	3.1
Diclofenac Potassium, Film Coated	4	3.0	3.0
Diclofenac Potassium Tablets	4	3.0	3.0
Fentanyl Citrate	8	2.8	2.8
Conjugated Estrogens And Medroxyprogesterone Acetate	9	2.4	2.4
Deferasirox	10	2.4	2.4
Loratadine And Pseudoephedrine Sulfate	3	2.4	2.4
Diclofenac Potassium	4	2.4	2.4
Secukinumab	59	2.3	2.3
Dabigatran Etexilate Mesylate	25	2.2	2.2
Denosumab	66	2.1	2.1
Medroxyprogesterone Acetate	16	2.0	2.0
Hydrocodone Bitartrate	9	1.3	1.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.