Reaction

Which drugs are most reported with Infusion site erythema?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 8,182 reports · 426 co-occurring drugs

As of the last recalculation, Infusion Site Erythema appears in 8,182 FAERS reports alongside 426 co-occurring drug terms. The strongest observed disproportionality signal is TREPROSTINIL (PRR 110.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Treprostinil	3,287	110.7	113.7
Ketoprofen	477	98.2	101.8
Human Immunoglobulin G	499	65.5	67.1
Amitriptyline Hydrochloride	421	64.3	65.9
Diphenhydramine Hydrochloride Capsule, Liquid Filled	309	38.2	38.7
Lidocaine Hydrochloride	810	37.8	38.3
Macitentan	882	36.2	36.7
0Xygen	631	35.2	35.7
Oxygen	631	35.2	35.7
Sildenafil Powder,	461	34.9	35.3
Sildenafil	722	34.7	35.1
Adrenalinum	507	33.1	33.5
Riociguat	376	30.7	31.0
Tadalafil	1,054	30.6	30.9
Sodium Chloride Tablet	703	26.5	26.7
Sodium Chloride Tablets	703	26.5	26.7
Epinephrine	618	25.9	26.1
Clonidine	485	25.5	25.8
Sodium Chloride	712	25.0	25.2
Sildenafil Citrate	1,077	24.6	24.8
Diphenhydramine	554	23.9	24.1
Lidocaine	499	23.1	23.3
Ambrisentan	944	21.6	21.8
Lidocaine, Menthol	363	19.4	19.6
Lidicaine	357	19.4	19.5
Burn Relief	357	19.4	19.5
Lidocaine Hydrochloride And Epinephrine	357	19.3	19.5
Cetirizine Hcl	68	19.0	19.1
Selexipag	180	18.1	18.2
Lidocaine Hydrochloride And Epinephrine Bitartrate	357	17.7	17.9
Lidocaine 4%	359	17.5	17.6
Diphenhydramine Hydrochloride	936	16.1	16.2
Epoprostenol	82	16.1	16.2
Azelastine	104	14.9	15.0
Hydroxyzine Hydrochloride	70	13.6	13.7
Hydroxyzine Hydrochloride Oral	70	13.6	13.7
Cyclobenzaprine Hydrochloride	46	13.1	13.2
Buspirone Hydrochloride	56	13.0	13.1
Bosentan	250	13.0	13.0
Fluticasone Propionate Nasal	149	12.7	12.8
Metolazone	53	12.1	12.1
Torsemide	148	11.6	11.6
Bumetanide	115	11.2	11.3
Dimenhydrinate	42	10.1	10.1
Butalbital, Acetaminophen, And Caffeine	42	10.1	10.1
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	79	9.9	9.9
Naproxen Sodium, Pseudoephedrine Hydrochloride	79	9.8	9.9
Acetaminophen Tablet Extended Release	825	9.0	9.1
Pain Reliever	825	9.0	9.1
Acetaminophen 500Mg	825	9.0	9.1
Potassium Chloride, Dextrose Monohydrate	314	8.9	9.0
Potassium Chloride Oral	314	8.9	9.0
Potassium Chloride Extended-Release	314	8.9	9.0
Tiotropium Bromide Inhalation Spray	39	8.9	8.9
Pantoprazole Sodium In 0.9% Sodium Chloride	199	8.3	8.4
Pantoprazole Sodium Injection	199	8.3	8.4
Iron Sucrose	31	8.3	8.3
Levocetirizine Dihydrochloride	77	8.2	8.2
Rosuvastatin Calcium	90	8.2	8.2
Potassium Chloride	352	8.2	8.2
Guaifenesin	96	8.1	8.1
Acetaminophen	1,233	8.1	8.1
Benzonatate	50	7.7	7.8
Spironolactone	408	7.7	7.7
Dicyclomine Hydrochloride	43	7.7	7.7
Fexofenadine Hydrochloride	65	7.7	7.7
Fluticasone Propionate	371	7.6	7.6
Amiodarone Hydrochloride	33	7.5	7.5
Atorvastatin Calcium, Film Coated	202	7.5	7.5
Fexofenadine Hcl	27	7.5	7.5
Tizanidine Hydrochloride	52	7.4	7.4
Triamcinolone Acetonide Ointment Usp, 0.05%	67	7.3	7.3
Doxyclycline Hyclate	48	7.2	7.2
Methocarbamol Tablets	47	7.2	7.2
Melatonin	151	7.2	7.2
Montelukast Sodium	315	6.8	6.8
Methocarbamol	59	6.7	6.7
Famotidine	296	6.6	6.6
Promethazine Hydrochloride	48	6.6	6.6
Mupirocin	34	6.4	6.4
Ondansetron Hydrochloride	296	6.3	6.4
Ipratropium Bromide	88	6.3	6.3
Mupirocin Calcium	34	6.3	6.3
Montelukast	203	6.3	6.3
Azithromycin	96	6.1	6.1
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	366	6.0	6.1
Fluticasone Furoate And Vilanterol Trifenatate	84	6.0	6.0
Azithromycin Monohydrate	96	5.9	5.9
Magnesium	187	5.9	5.9
Triamcinolone Acetonide	71	5.9	5.9
Bendamustine Hydrochloride	27	5.8	5.8
Ferrous Sulfate	112	5.7	5.7
Umeclidinium	20	5.7	5.7
Gabapentin	754	5.7	5.7
Budesonide, Glycopyrrolate, And Formoterol Fumarate	23	5.6	5.6
Warfarin	272	5.6	5.6
Loratadine Oral	106	5.5	5.6
Infliximab-Dyyb	63	5.5	5.5
Vitamin C	195	5.5	5.5
Zinc Gluconate	56	5.5	5.5
Meclizine	35	5.5	5.5
Rotigotine	31	5.5	5.5
Biotin	66	5.4	5.4
Mometasone Furoate And Formoterol Fumarate Dihydrate	33	5.4	5.4
Zinc	52	5.4	5.4
Metoprolol Succinate Er Tablets	130	5.4	5.4
Zinc Chloride	52	5.4	5.4
Oxybutynin Chloride	18	5.2	5.2
Pantoprazole Sodium	293	5.2	5.2
Azithromycin Dihydrate	116	5.1	5.1
Hyoscyamine Sulfate	18	5.0	5.0
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	59	5.0	5.0
Meclizine Hydrochloride	38	5.0	5.0
Hydroxyzine	92	5.0	5.0
Amantadine	30	4.9	5.0
Albuterol Sulfate	545	4.9	4.9
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	96	4.9	4.9
Warfarin Sodium	89	4.9	4.9
Psyllium Husk	19	4.9	4.9
Loratadine	200	4.8	4.8
Esomeprazole Magnesium Capsule, Delayed Release	27	4.7	4.8
Esomeprazole Magnesium Delayed Release Capsules	27	4.7	4.8
Ergocalciferol	669	4.7	4.7
Esomeprazole Magnesium Dihydrate	27	4.7	4.7
Loperamide Hydrochloride	82	4.7	4.7
Meperidine Hydrochloride	17	4.7	4.7
Aprepitant	34	4.7	4.7
Fosaprepitant Dimeglumine	25	4.6	4.6
Cetirizine Hydrochloride	291	4.6	4.6
Iron	118	4.5	4.5
Docusate Sodium 100Mg	42	4.5	4.5
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	72	4.5	4.5
Cetirizine	134	4.4	4.5
Fluticasone Propionate And Salmeterol Xinafoate	104	4.4	4.5
Metoprolol Succinate	148	4.4	4.4
Metformin Hydrochloride Tablets	98	4.4	4.4
Liothyronine Sodium	15	4.4	4.4
Metformin Hydrochloride Extended-Release Tablets	98	4.4	4.4
Metformin Hydrochloride Tablet	98	4.4	4.4
Sucralfate	41	4.4	4.4
Colchicine	45	4.4	4.4
Estradiol Gel 0.1%	76	4.3	4.3
Estradiol Transdermal	76	4.3	4.3
Thyroid, Porcine	18	4.3	4.3
Oxycodone And Acetaminophen Tablets	20	4.3	4.3
Rizatriptan Benzoate	17	4.3	4.3
Loratadine Tablet	89	4.3	4.3
Metformin Hydrochloride	98	4.3	4.3
Levothyroxine Sodium Anhydrous	163	4.2	4.2
Pramipexole	25	4.2	4.2
Loperamide Hydrochloride And Dimethicone	52	4.1	4.2
Pravastatin Sodium	32	4.1	4.1
Diphenhydramine Hcl	18	4.1	4.1
Cyanocobalamin	53	4.1	4.1
Nystatin Ointment	42	4.1	4.1
Furosemide	608	4.1	4.1
Alemtuzumab	31	4.1	4.1
Nystatin Cream	42	4.1	4.1
Budesonide And Formoterol Fumarate Dihydrate	153	4.1	4.1
Amoxicillin And Clavulanate Potassium	43	4.0	4.0
Cyclobenzaprine	78	4.0	4.0
Nystatin	42	3.9	3.9
Methimazole	12	3.9	3.9
Ropinirole	23	3.8	3.8
Digoxin	105	3.8	3.8
Mometasone Furoate	61	3.7	3.7
Ciclesonide	20	3.7	3.7
Chlorthalidone	17	3.7	3.7
Docusate Sodium	84	3.7	3.7
Clobetasol Propionate Ointment Usp, 0.05%	15	3.7	3.7
Carfilzomib	41	3.7	3.7
Instalax Polyethylene Glycol 3350	18	3.7	3.7
Clobetasol Propionate	15	3.7	3.7
Rasagiline Mesylate	16	3.7	3.7
Polyethylene Glycol 400	18	3.6	3.6
Doxycycline Hyclate	95	3.6	3.6
Doxycycline	96	3.6	3.6
Magnesium Oxide	59	3.6	3.6
Sucralfate Oral	20	3.6	3.6
Cholestyramine	17	3.6	3.6
Sucralfate Oral Suspension	20	3.6	3.6
Progesterone	32	3.6	3.6
Guanfacine	11	3.6	3.6
Cephalexin	30	3.5	3.5
Hydrocortisone Sodium Succinate	13	3.5	3.5
Thiamine Hydrochloride	17	3.5	3.5
Remdesivir	18	3.4	3.4
Valacyclovir	56	3.4	3.4
Fluticasone Furoate	16	3.4	3.4
Meclizine Hcl 12.5Mg	18	3.4	3.4
Meclizine Hcl 25Mg	18	3.4	3.4
Meclizine Hcl 12.5 Mg	18	3.4	3.4
Meclizine Hcl 25 Mg	18	3.4	3.4
Diltiazem Hydrochloride Extended-Release Tablets	15	3.4	3.4
Diphenoxylate Hydrochloride And Atropine Sulfate	18	3.3	3.4
Tolvaptan	19	3.3	3.3
Valacyclovir Hydrochloride	91	3.3	3.3
Agalsidase Beta	12	3.3	3.3
Drs. Clotrimazole	15	3.3	3.3
Family Wellness Clotrimazole	15	3.3	3.3
Clotrimazole Topical	15	3.3	3.3
Carbidopa And Levodopa	61	3.3	3.3
Pantoprazole	314	3.2	3.2
Lubiprostone	12	3.2	3.2
Mometasone	23	3.2	3.2
Estradiol	107	3.2	3.2
Anti-Itch	83	3.2	3.2
Anti-Pruritic	83	3.2	3.2
Antipruritic (Anti-Itch)	83	3.2	3.2
Cool Relief Gel With Aloe	83	3.2	3.2
Drs. Hydrocortisone	83	3.2	3.2
Hydrocortisone Continuous Spray	83	3.2	3.2
Hydrocortisone Spray	83	3.2	3.2
Anti-Itch Cream	83	3.2	3.2
Hydrocortisone Lotion	83	3.2	3.2
Hydrocortisone Cream 1%	83	3.2	3.2
Hydrocortisone Cream 1/2%	83	3.2	3.2
Hydrocortisone 1%	83	3.2	3.2
Docusate Sodium - Sennosides	40	3.2	3.2
Hydrocortisone Cream	83	3.2	3.2
Budesonide	72	3.1	3.1
Cefuroxime	14	3.1	3.1
Clotrimazole	15	3.1	3.1
Hydrocortisone	108	3.1	3.1
Hydrocortisone Acetate	88	3.1	3.1
Hydroxychloroquine Sulfate	110	3.1	3.1
Timolol Maleate	12	3.1	3.1
Ondansetron	130	3.1	3.1
Ondansetron Tablets	130	3.1	3.1
Polyethylene Glycol	13	3.1	3.1
Cetirizine Hydrochloride Allergy	36	3.0	3.0
Cetirizine Hydrochloride Tablets	36	3.0	3.0
Sumatriptan Succinate	30	3.0	3.0
Calcium	173	3.0	3.0
Phytonadione	10	3.0	3.0
Primidone	12	3.0	3.0
Rabeprazole	26	3.0	3.0
Carboxymethylcellulose Sodium	11	3.0	3.0
Ciprofloxacin Hydrochloride And Hydrocortisone	24	2.9	2.9
Ketoconazole Foam	17	2.9	2.9
Losartan Potassium	90	2.9	2.9
Ketoconazole Cream, 2%	17	2.9	2.9
Atorvastatin Calcium	277	2.9	2.9
Acetaminophen, Aspirin, And Caffeine	24	2.9	2.9
Umeclidinium Bromide And Vilanterol Trifenatate	19	2.9	2.9
Fish Oil	102	2.9	2.9
Levothyroxine Sodium	345	2.9	2.9
Vitamin E	35	2.8	2.8
Sulfamethoxazole And Trimethoprim	91	2.8	2.8
Bisacodyl Suppositories	14	2.8	2.8
Duloxetine	75	2.8	2.8
Ursosiol	21	2.8	2.8
Tamsulosin Hydrochloride	22	2.7	2.7
Biscodyl	14	2.7	2.7
Cetiirizine	45	2.7	2.7
Empagliflozin	71	2.7	2.7
Albuterol	126	2.7	2.7
Linaclotide	28	2.7	2.7
Tizanidine	25	2.7	2.7
Diltiazem Hydrochloride	36	2.7	2.7
Cimetidine	10	2.6	2.6
Mirabegron	40	2.6	2.6
Dexlansoprazole	43	2.6	2.6
Clindamycin	29	2.6	2.6
Eplerenone	13	2.6	2.6
Testosterone Cypionate	9	2.6	2.6
Tolterodine Tartrate	9	2.6	2.6
Bisacodyl	14	2.5	2.5
Fondaparinux Sodium	8	2.5	2.5
Dextrose	13	2.5	2.5
Ketoconazole	17	2.5	2.5
Prochlorperazine Maleate	9	2.5	2.5
Vilazodone Hydrochloride	9	2.5	2.5
Dextrose Monohydrate	13	2.5	2.5
Sumatriptan	37	2.5	2.5
Sertraline Hydrochloride	114	2.5	2.5
Prednisolone Acetate	10	2.5	2.5
Ursodiol	21	2.5	2.5
Amoxicillin	73	2.4	2.4
Fluconazole	67	2.4	2.4
Rivastigmine	18	2.4	2.4
Nifedipine	45	2.4	2.4
Acetylcysteine	9	2.4	2.4
Standardized Senna Concentrate	12	2.4	2.4
Diclofenac Sodium 1%	34	2.4	2.4
Diclofenac Sodium Topical	34	2.4	2.4
Diclofenac Sodium Topical Gel, 1%	34	2.4	2.4
Polyethylene Glycol 3350	90	2.4	2.4
Bupropion Hydrochloride	92	2.4	2.4
Aspirin 81 Mg	460	2.4	2.4
Aspirin 325 Mg	459	2.4	2.4
Erythromycin	17	2.3	2.3
Valganciclovir Hydrochloride Powder,	11	2.3	2.3
Oxycodone And Acetaminophen	21	2.3	2.3
Labetalol	12	2.3	2.3
Clindamycin Phosphate	30	2.3	2.3
Meloxicam	52	2.3	2.3
Aspirin	467	2.3	2.3
Nintedanib	28	2.3	2.3
Teduglutide	12	2.3	2.3
Tobramycin Sulfate	11	2.3	2.3
Amlodipine Besylate	128	2.2	2.2
Zonisamide	13	2.2	2.2
Memantine	12	2.2	2.2
Memantine Hydrochloride	12	2.2	2.2
Duloxetine Hydrochloride	163	2.2	2.2
Vibegron	7	2.2	2.2
Rimegepant Sulfate	11	2.2	2.2
Tretinoin	7	2.2	2.2
Sennosides 8.6 Mg Tablets	18	2.2	2.2
Itraconazole	10	2.2	2.2
Senna	18	2.2	2.2
Omeprazole	287	2.2	2.2
Escitalopram	117	2.1	2.1
Desloratadine	9	2.1	2.1
Tobramycin Solution	10	2.1	2.1
Rivaroxaban	171	2.1	2.1
Levodopa	10	2.1	2.1
Senna Leaf	19	2.1	2.1
Acetaminophen, Aspirin (Nsaid) And Caffeine	14	2.1	2.1
Ezetimibe	61	2.1	2.1
Topiramate	74	2.0	2.0
Metoroprolol Tartrate	52	2.0	2.0
Tranexamic Acid	7	2.0	2.0
Escitalopram Oxalate	57	2.0	2.0
Lactulose	30	2.0	2.0
Ibuprofen Tablets, Coated	33	2.0	2.0
Ciprofloxacin Hydrochloride	75	2.0	2.0
Ibuprofen Sodium	33	2.0	2.0
Clonazepam	122	2.0	2.0
Dofetilide	8	1.9	1.9
Omeprazole Magnesium	333	1.9	1.9
Ibuprofen Capsule	150	1.9	1.9
Ibuprofen Tablet, Film Coated	150	1.9	1.9
Ibupfrofen	150	1.9	1.9
Ibuprofen Tablets Usp, 200Mg	150	1.9	1.9
Ibuprofen Oral	150	1.9	1.9
Ibuprofen Capsules 200 Mg	150	1.9	1.9
Ibuprofen 200 Mg	150	1.9	1.9
Ibuprofen 200Mg	150	1.9	1.9
Ibuprofen	203	1.9	1.9
Levofloxacin	45	1.9	1.9
Levofloxacin In 5% Dextrose	45	1.9	1.9
Dronabinol	6	1.9	1.9
Valganciclovir	14	1.9	1.9
Valganciclovir Hydrochloride	14	1.9	1.9
Acetaminophen And Codeine	9	1.9	1.9
Baclofen	62	1.8	1.8
Fluticasone Propionate And Salmeterol	30	1.8	1.8
Mycophenolate Mofetil	96	1.8	1.8
Donepezil Hydrochloride	26	1.8	1.8
Mycophenolate Mofetil Hydrochloride	96	1.8	1.8
Desvenlafaxine Succinate	19	1.8	1.8
Sennosides	21	1.8	1.8
Hydrochlorothiazide	101	1.8	1.8
Fremanezumab-Vfrm	8	1.8	1.8
Insulin Glargine-Yfgn	15	1.7	1.7
Pitavastatin Calcium	7	1.7	1.7
Vancomycin Hydrochloride	45	1.7	1.7
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	24	1.7	1.7
Mycophenilic Acid	14	1.7	1.7
Oral Semaglutide	49	1.7	1.7
Citalopram Hydrobromide	71	1.7	1.7
Latanoprost	33	1.7	1.7
Mycophenolic Acid	21	1.7	1.7
Losartan	114	1.7	1.7
Rosuvastatin	133	1.7	1.7
Nebivolol Hydrochloride	22	1.7	1.7
Tiotropium Bromide	86	1.6	1.6
Eszopiclone	16	1.6	1.6
Oseltamivir	5	1.6	1.6
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	26	1.6	1.6
Rifaximin	13	1.6	1.6
Oxcarbazepine	20	1.6	1.6
Benralizumab	12	1.5	1.5
Vortioxetine	10	1.5	1.5
Oxycodone Hydrochloride And Acetaminophen	56	1.4	1.4
Brimonidine Tartrate	10	1.4	1.4
Naproxen Sodium Tablet	29	1.4	1.4
Oxybutynin	16	1.4	1.4
Vedolizumab	47	1.4	1.4
Medroxyprogesterone Acetate	27	1.4	1.4
Oxycodone	100	1.4	1.4
Naproxen Sodium Tablet, Coated	7	1.3	1.3
Naproxen Sodium, Coated Tablets	7	1.3	1.3
Naproxen Sodium 220Mg	7	1.3	1.3
Insulin Lispro	71	1.3	1.3
Oseltamivir Phosphate	12	1.3	1.3
Lisdexamfetamine Dimesylate	16	1.2	1.2
Icosapent Ethyl	4	1.2	1.2
Omalizumab	40	1.2	1.2
Insulin Degludec	11	1.2	1.2
Apixaban	31	1.2	1.2
Travoprost	4	1.2	1.2
Atomoxetine Hydrochloride	11	1.2	1.2
Methadone Hydrochloride	5	1.2	1.2
Miconazole Nitrate	4	1.2	1.2
Tobramycin	11	1.2	1.2
Galcanezumab-Gnlm	14	1.1	1.1
Docetaxel	29	1.1	1.1
Bimatoprost	12	1.1	1.1
Acalabrutinib	5	1.0	1.0
Naltrexone	12	1.0	1.0
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	7	1.0	1.0
Ranolazine	4	1.0	1.0
Belimumab	12	1.0	1.0
Docetaxel Anhydrous	25	0.9	0.9
Diclofenac Potassium	4	0.9	0.9
Iohexol	3	0.9	0.9
Cannabidiol	8	0.9	0.9
Alteplase	5	0.8	0.8
Ranitidine	66	0.8	0.8
Eptinezumab-Jjmr	3	0.8	0.8
Lifitegrast	5	0.8	0.8
Brexpiprazole	5	0.8	0.8
Fam-Trastuzumab Deruxtecan-Nxki	3	0.8	0.8
Ravulizumab	4	0.8	0.8
Natalizumab	40	0.6	0.6
Glycerin, Lidocaine	3	0.5	0.5
Docosanol	3	0.5	0.5
Dornase Alfa	4	0.5	0.5
Droxidopa	4	0.5	0.5
Pimavanserin Tartrate	10	0.5	0.5
Etonogestrel	7	0.4	0.4
Erenumab-Aooe	8	0.4	0.4
Tirzepatide	19	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.