Drug

Tocilizumab

1,276 flagged reaction(s) · 1,098,780 total co-reports · max PRR 2,249.6

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Human Antichimeric Antibody Positive	310	2,249.6	2,255.8	signal
2	Disability Assessment Scale Score Increased	268	1,246.7	1,249.6	signal
3	Anti-cyclic Citrullinated Peptide Antibody Positive	5,915	975.5	1,029.2	signal
4	Rheumatoid Factor Positive	4,595	757.8	789.8	signal
5	Rheumatoid Factor Negative	138	676.6	677.5	signal
6	Anti-cyclic Citrullinated Peptide Antibody	518	666.5	669.5	signal
7	Swollen Joint Count Increased	2,404	646.1	660.1	signal
8	Rheumatic Fever	3,320	607.2	625.5	signal
9	Pemphigus	9,201	543.9	591.8	signal
10	Red Blood Cell Sedimentation Rate	208	539.1	540.1	signal
11	Deep Vein Thrombosis Postoperative	1,381	451.4	457.0	signal
12	Duodenal Ulcer Perforation	5,011	406.8	425.5	signal
13	Lupus Vulgaris	807	397.8	400.7	signal
14	C-reactive Protein	614	395.0	397.2	signal
15	Granuloma Skin	525	325.1	326.6	signal
16	Facet Joint Syndrome	1,954	306.1	311.5	signal
17	Swollen Joint Count	150	292.6	293.0	signal
18	Hand Deformity	7,961	291.7	313.6	signal
19	Hepatic Enzyme	85	291.0	291.2	signal
20	Red Blood Cell Sedimentation Rate Abnormal	1,380	273.0	276.4	signal
21	Grip Strength	137	270.2	270.5	signal
22	C-reactive Protein Abnormal	3,774	268.5	277.7	signal
23	Synovitis	10,546	263.3	290.2	signal
24	Musculoskeletal Deformity	135	249.9	250.2	signal
25	X-ray Abnormal	951	212.7	214.5	signal
26	Muscle Injury	4,172	192.6	200.0	signal
27	Adjustment Disorder With Depressed Mood	1,018	190.0	191.7	signal
28	Helicobacter Infection	5,103	186.7	195.4	signal
29	Body Height Below Normal	322	182.6	183.1	signal
30	Sleep Disorder Due To General Medical Condition, Insomnia Type	3,133	176.4	181.4	signal
31	Presbyacusis	147	166.7	166.9	signal
32	Dislocation Of Vertebra	1,043	164.1	165.6	signal
33	Folliculitis	4,662	152.9	159.4	signal
34	Bone Erosion	1,573	148.3	150.4	signal
35	Joint Laxity	131	141.5	141.6	signal
36	Blood Parathyroid Hormone Decreased	612	129.1	129.8	signal
37	Anticipatory Anxiety	110	127.1	127.2	signal
38	Contraindicated Product Administered	12,157	125.2	140.1	signal
39	Retinitis	672	124.9	125.7	signal
40	Subcutaneous Drug Absorption Impaired	218	123.6	123.8	signal
41	Glossodynia	8,500	113.7	122.8	signal
42	Pericarditis	6,199	109.7	116.0	signal
43	Short Stature	96	107.5	107.6	signal
44	Seronegative Arthritis	405	104.5	104.9	signal
45	Peripheral Venous Disease	1,431	103.4	104.7	signal
46	Rheumatoid Nodule	994	102.8	103.7	signal
47	Blood Iron Abnormal	348	101.7	102.0	signal
48	Blood Pressure Diastolic Abnormal	891	98.2	99.0	signal
49	Drug Tolerance Decreased	919	90.4	91.1	signal
50	Blood Pressure Systolic Abnormal	809	89.0	89.6	signal
51	Ankle Arthroplasty	111	82.9	83.0	signal
52	Intestinal Sepsis	77	80.7	80.8	signal
53	Joint Destruction	461	77.2	77.5	signal
54	Panniculitis	680	72.6	73.0	signal
55	Loose Body In Joint	74	71.0	71.1	signal
56	Systemic Lupus Erythematosus	9,732	70.1	76.6	signal
57	Wound	7,272	65.4	69.8	signal
58	Hypocholesterolaemia	78	62.6	62.7	signal
59	Juvenile Idiopathic Arthritis	604	60.4	60.7	signal
60	Red Blood Cell Sedimentation Rate Increased	2,692	59.2	60.6	signal
61	Temperature Regulation Disorder	513	56.6	56.9	signal
62	Breast Cancer Stage Iii	1,509	56.5	57.3	signal
63	Red Cell Distribution Width Decreased	106	54.8	54.8	signal
64	Onychomadesis	915	52.1	52.5	signal
65	Porphyria Acute	301	51.4	51.6	signal
66	Bursitis	2,589	50.4	51.6	signal
67	Grip Strength Decreased	1,868	50.1	50.9	signal
68	Irritable Bowel Syndrome	4,554	50.0	52.0	signal
69	Giant Cell Arteritis	169	48.8	48.9	signal
70	Lip Dry	1,864	48.4	49.2	signal
71	Amaurosis Fugax	220	47.7	47.8	signal
72	Rheumatoid Lung	196	47.1	47.2	signal
73	Joint Range Of Motion Decreased	2,714	47.0	48.1	signal
74	Rheumatoid Arthritis	22,731	46.4	57.8	signal
75	Onychomycosis	869	45.6	46.0	signal
76	Hypercholesterolaemia	1,878	45.0	45.8	signal
77	Arthropathy	10,904	44.8	49.5	signal
78	Overlap Syndrome	132	43.6	43.7	signal
79	Therapeutic Product Effect Decreased	8,005	40.6	43.6	signal
80	Wound Infection	1,960	40.6	41.3	signal
81	Tenosynovitis	494	40.1	40.3	signal
82	Pleural Thickening	119	39.0	39.0	signal
83	Fibromyalgia	4,084	37.3	38.6	signal
84	Bone Cyst	156	36.7	36.7	signal
85	Nail Operation	66	35.2	35.2	signal
86	Joint Ankylosis	92	35.2	35.2	signal
87	Antibody Test Positive	269	35.1	35.2	signal
88	Impaired Healing	5,211	34.8	36.4	signal
89	Blepharospasm	959	33.7	34.0	signal
90	Finger Deformity	730	32.7	32.9	signal
91	Autoimmune Disorder	1,426	32.3	32.7	signal
92	Live Birth	1,232	32.0	32.3	signal
93	Pleural Fibrosis	152	31.9	31.9	signal
94	Infusion Related Reaction	9,448	30.8	33.5	signal
95	Mean Platelet Volume Decreased	117	30.2	30.2	signal
96	Wrist Deformity	87	30.1	30.1	signal
97	Systemic Lupus Erythematosus Rash	112	29.9	29.9	signal
98	Liver Injury	3,318	29.3	30.1	signal
99	Vascular Access Complication	111	29.3	29.3	signal
100	Drug Intolerance	13,120	29.1	32.7	signal
101	Joint Swelling	16,323	28.9	33.6	signal
102	Infusion Site Reaction	390	28.5	28.6	signal
103	Interleukin Level Increased	71	28.2	28.3	signal
104	Arthrodesis	134	27.9	28.0	signal
105	Joint Arthroplasty	234	27.6	27.7	signal
106	Blood Magnesium Increased	117	27.4	27.4	signal
107	Polyarthritis	677	27.3	27.4	signal
108	Sciatica	2,044	27.2	27.7	signal
109	Hepatic Enzyme Increased	8,667	26.9	29.1	signal
110	Nail Disorder	1,108	26.9	27.2	signal
111	Coeliac Disease	1,250	26.9	27.2	signal
112	Obesity	2,015	26.6	27.1	signal
113	Lower Respiratory Tract Infection	5,665	26.3	27.6	signal
114	Treatment Failure	10,085	25.8	28.2	signal
115	Limb Deformity	195	25.6	25.7	signal
116	Maternal Exposure Timing Unspecified	445	25.0	25.1	signal
117	Allergy To Chemicals	148	24.8	24.9	signal
118	Soft Tissue Disorder	132	24.6	24.7	signal
119	Intercepted Product Storage Error	401	24.5	24.6	signal
120	C-reactive Protein Increased	4,271	24.5	25.4	signal
121	Pulmonary Fibrosis	2,228	24.3	24.8	signal
122	Foot Deformity	1,293	24.3	24.6	signal
123	Type 2 Diabetes Mellitus	3,906	24.1	24.9	signal
124	Hip Arthroplasty	1,748	24.0	24.3	signal
125	Enthesopathy	180	23.7	23.8	signal
126	Tenosynovitis Stenosans	63	23.4	23.4	signal
127	Swelling	10,488	23.3	25.6	signal
128	Psoriatic Arthropathy	4,479	23.1	24.0	signal
129	Death Neonatal	153	23.0	23.0	signal
130	Skin Necrosis	572	22.7	22.8	signal
131	Blood Pressure Diastolic Increased	507	22.6	22.7	signal
132	Blood Pressure Diastolic Decreased	805	22.4	22.6	signal
133	C-reactive Protein Decreased	70	22.2	22.2	signal
134	Investigation Abnormal	146	21.6	21.6	signal
135	Exostosis	951	21.4	21.6	signal
136	Hypofibrinogenaemia	101	21.4	21.4	signal
137	Apparent Death	354	19.8	19.8	signal
138	Prescribed Overdose	1,861	19.6	19.9	signal
139	Discomfort	5,815	19.5	20.5	signal
140	Knee Arthroplasty	1,999	19.5	19.9	signal
141	Blood Cholesterol Increased	4,352	18.9	19.7	signal
142	Blister	5,223	18.9	19.8	signal
143	Drug Specific Antibody	127	18.9	18.9	signal
144	Food Allergy	693	18.6	18.7	signal
145	Stomatitis	5,562	18.6	19.5	signal
146	Lower Respiratory Tract Congestion	156	18.6	18.6	signal
147	Lupus-like Syndrome	809	18.1	18.3	signal
148	Drug Tolerance	437	17.3	17.4	signal
149	Alanine Aminotransferase Abnormal	180	17.3	17.3	signal
150	Immunodeficiency	1,251	17.1	17.3	signal
151	Walking Aid User	562	17.1	17.1	signal
152	Osteoarthritis	3,581	16.9	17.5	signal
153	Bronchitis Chronic	207	16.9	17.0	signal
154	Mean Cell Volume Decreased	130	16.9	16.9	signal
155	Pustular Psoriasis	288	16.8	16.8	signal
156	Product Label Confusion	479	16.5	16.6	signal
157	Ill-defined Disorder	4,970	16.4	17.1	signal
158	Infected Bite	68	16.4	16.4	signal
159	Musculoskeletal Stiffness	7,135	16.3	17.3	signal
160	Lower Limb Fracture	1,533	16.1	16.3	signal
161	Back Injury	865	16.0	16.1	signal
162	Joint Dislocation	839	15.9	16.0	signal
163	Gait Inability	2,637	15.9	16.3	signal
164	Loss Of Personal Independence In Daily Activities	3,712	15.6	16.1	signal
165	Inflammation	3,975	15.4	16.0	signal
166	Liver Function Test Increased	1,639	15.3	15.5	signal
167	Laryngitis	832	15.3	15.4	signal
168	Blood Pressure Systolic Increased	1,498	15.2	15.4	signal
169	Joint Stiffness	2,000	15.2	15.4	signal
170	Mean Cell Haemoglobin Decreased	140	15.2	15.2	signal
171	Pneumonia Viral	240	15.0	15.0	signal
172	Immobile	316	14.4	14.4	signal
173	Osteoporotic Fracture	139	14.3	14.3	signal
174	Immune Effector Cell-associated Neurotoxicity Syndrome	405	14.3	14.3	signal
175	Mobility Decreased	5,131	14.2	14.8	signal
176	Maternal Exposure During Pregnancy	6,310	14.2	15.0	signal
177	Night Sweats	2,303	14.2	14.4	signal
178	Intercepted Medication Error	333	14.1	14.1	signal
179	Retinal Toxicity	72	14.0	14.0	signal
180	Rheumatoid Factor Increased	79	14.0	14.0	signal
181	Oral Mucosal Exfoliation	106	13.8	13.8	signal
182	Haemophagocytic Lymphohistiocytosis	503	13.8	13.8	signal
183	Synovial Cyst	320	13.6	13.7	signal
184	Fine Motor Skill Dysfunction	197	13.5	13.5	signal
185	Spondylitis	248	13.5	13.5	signal
186	Surgical Failure	78	13.3	13.3	signal
187	Pruritus Allergic	77	13.0	13.0	signal
188	Scleritis	105	12.9	13.0	signal
189	Ear Pain	1,266	12.8	12.9	signal
190	Eye Injury	195	12.7	12.8	signal
191	Prescribed Underdose	1,292	12.7	12.9	signal
192	Joint Effusion	446	12.7	12.7	signal
193	Bone Swelling	62	12.5	12.5	signal
194	Limb Mass	139	12.5	12.5	signal
195	Abdominal Discomfort	10,569	12.4	13.6	signal
196	Diverticular Perforation	129	12.2	12.2	signal
197	Breast Cancer Stage Ii	519	12.1	12.2	signal
198	Intentional Product Use Issue	5,414	12.1	12.6	signal
199	Pulmonary Toxicity	432	12.1	12.1	signal
200	Ulcer Haemorrhage	416	12.1	12.1	signal
201	Deformity	576	12.0	12.1	signal
202	Musculoskeletal Pain	3,241	12.0	12.4	signal
203	Drug Eruption	1,073	11.9	12.0	signal
204	Demyelination	249	11.8	11.9	signal
205	Urinary Tract Disorder	264	11.5	11.5	signal
206	Arthritis Bacterial	239	11.4	11.5	signal
207	Congenital Anomaly	455	11.4	11.4	signal
208	Systemic Candida	144	11.4	11.4	signal
209	Peripheral Swelling	8,900	11.3	12.2	signal
210	Sinusitis	5,940	11.3	11.9	signal
211	Body Temperature Decreased	573	11.3	11.3	signal
212	Infection	8,275	11.2	12.0	signal
213	Hepatic Cirrhosis	1,070	11.2	11.3	signal
214	Foetal Death	295	11.1	11.1	signal
215	Drug Delivery System Malfunction	286	11.0	11.1	signal
216	Muscle Spasticity	698	11.0	11.0	signal
217	Skin Ulcer	1,433	10.8	10.9	signal
218	Blood Fibrinogen Decreased	62	10.8	10.8	signal
219	Hypersensitivity	10,207	10.7	11.7	signal
220	Alopecia	10,737	10.6	11.6	signal
221	Arthritis Infective	250	10.5	10.5	signal
222	Hypercalcaemia	665	10.5	10.5	signal
223	Gastrointestinal Disorder	4,734	10.4	10.8	signal
224	Diverticulitis	1,472	10.4	10.5	signal
225	Histiocytosis Haematophagic	160	10.3	10.3	signal
226	Sleep Disorder	3,702	10.3	10.6	signal
227	Rash Vesicular	254	10.2	10.3	signal
228	Wheelchair User	233	10.1	10.1	signal
229	Adrenal Insufficiency	623	10.1	10.1	signal
230	Spinal Column Injury	115	10.0	10.0	signal
231	Liver Disorder	2,280	10.0	10.2	signal
232	Prerenal Failure	71	9.9	9.9	signal
233	Hepatitis	1,297	9.8	9.9	signal
234	Nodule	657	9.8	9.8	signal
235	Basal Cell Carcinoma	785	9.7	9.8	signal
236	Crepitations	150	9.7	9.7	signal
237	Colitis Microscopic	232	9.6	9.6	signal
238	Gastrointestinal Perforation	204	9.5	9.5	signal
239	Lung Disorder	2,396	9.5	9.6	signal
240	Monocyte Count Increased	178	9.5	9.5	signal
241	Therapy Non-responder	2,178	9.5	9.6	signal
242	Deafness Neurosensory	160	9.4	9.5	signal
243	Pneumonia Fungal	187	9.3	9.3	signal
244	Infectious Pleural Effusion	72	9.2	9.2	signal
245	Cushingoid	153	9.1	9.2	signal
246	Ulcer	750	9.1	9.1	signal
247	Cutaneous Vasculitis	168	9.1	9.1	signal
248	Osteoporosis	1,935	9.1	9.2	signal
249	Wheezing	2,733	8.9	9.1	signal
250	Cytokine Release Syndrome	876	8.9	8.9	signal
251	Drug Hypersensitivity	8,879	8.8	9.5	signal
252	Epigastric Discomfort	179	8.8	8.8	signal
253	Blood Pressure Fluctuation	1,098	8.8	8.9	signal
254	Nasal Ulcer	73	8.8	8.8	signal
255	Injury	3,219	8.8	9.0	signal
256	Neoplasm Skin	69	8.5	8.5	signal
257	Contusion	4,262	8.5	8.8	signal
258	Spinal Stenosis	180	8.5	8.5	signal
259	General Physical Health Deterioration	5,026	8.4	8.8	signal
260	Body Temperature Increased	895	8.4	8.5	signal
261	Arthritis	3,431	8.4	8.6	signal
262	Intestinal Polyp	72	8.4	8.4	signal
263	Rheumatic Disorder	84	8.3	8.3	signal
264	Joint Noise	83	8.2	8.2	signal
265	Oedema	2,285	8.1	8.3	signal
266	Skin Papilloma	169	8.1	8.1	signal
267	Arthralgia	17,305	8.0	9.3	signal
268	Therapeutic Product Effect Incomplete	2,943	8.0	8.2	signal
269	Physical Disability	185	8.0	8.0	signal
270	Exposure During Pregnancy	2,579	8.0	8.1	signal
271	Spinal Fusion Surgery	166	7.9	7.9	signal
272	Viral Upper Respiratory Tract Infection	197	7.9	7.9	signal
273	Road Traffic Accident	1,710	7.8	7.9	signal
274	Nasopharyngitis	7,488	7.8	8.2	signal
275	Normal Newborn	220	7.8	7.8	signal
276	Bronchopulmonary Aspergillosis	312	7.7	7.8	signal
277	Taste Disorder	805	7.7	7.7	signal
278	Respiratory Disorder	1,200	7.7	7.7	signal
279	Drug-induced Liver Injury	1,225	7.6	7.7	signal
280	Adverse Reaction	526	7.6	7.6	signal
281	Disability	783	7.6	7.6	signal
282	Osteosclerosis	62	7.5	7.5	signal
283	Pneumonia Bacterial	358	7.5	7.5	signal
284	Vascular Rupture	61	7.5	7.5	signal
285	No Adverse Event	6,863	7.4	7.8	signal
286	White Blood Cell Count Abnormal	240	7.2	7.2	signal
287	Infected Skin Ulcer	71	7.2	7.2	signal
288	Growth Retardation	110	7.1	7.1	signal
289	Osteolysis	76	7.1	7.1	signal
290	Upper Respiratory Tract Infection	1,707	7.1	7.2	signal
291	Tuberculin Test Positive	94	7.0	7.0	signal
292	Joint Injury	782	7.0	7.0	signal
293	Pregnancy	732	6.9	6.9	signal
294	Blood Pressure Systolic Decreased	163	6.9	6.9	signal
295	Gastrointestinal Toxicity	169	6.8	6.9	signal
296	Epilepsy	1,092	6.8	6.9	signal
297	Product Use Issue	6,640	6.8	7.1	signal
298	Injection Site Hypersensitivity	109	6.8	6.8	signal
299	Pharyngitis	440	6.7	6.8	signal
300	Ear Infection	936	6.7	6.8	signal
301	Joint Lock	99	6.6	6.6	signal
302	Incorrect Route Of Product Administration	583	6.6	6.6	signal
303	Foot Operation	168	6.5	6.5	signal
304	Neurogenic Bladder	72	6.5	6.5	signal
305	Skin Laceration	367	6.5	6.5	signal
306	Covid-19 Pneumonia	397	6.4	6.4	signal
307	Weight Increased	7,429	6.3	6.7	signal
308	Hepatic Enzyme Abnormal	166	6.3	6.3	signal
309	Heart Rate Decreased	1,174	6.3	6.4	signal
310	Pain	20,222	6.3	7.4	signal
311	Delirium	1,134	6.2	6.3	signal
312	Localised Infection	788	6.2	6.2	signal
313	Haemorrhagic Stroke	255	6.2	6.2	signal
314	Myositis	290	6.1	6.2	signal
315	Condition Aggravated	9,632	6.1	6.5	signal
316	Rash	13,763	6.0	6.7	signal
317	Cardiotoxicity	279	6.0	6.0	signal
318	Lipids Increased	63	6.0	6.0	signal
319	Neck Pain	1,757	6.0	6.0	signal
320	Herpes Zoster	1,805	6.0	6.0	signal
321	Hypertension	6,548	5.9	6.2	signal
322	Urticaria	5,136	5.9	6.1	signal
323	Interstitial Lung Disease	1,477	5.8	5.9	signal
324	Hypertransaminasaemia	207	5.8	5.8	signal
325	Device Defective	491	5.8	5.8	signal
326	Antinuclear Antibody Positive	99	5.8	5.8	signal
327	Dry Mouth	2,413	5.6	5.7	signal
328	Pulmonary Mass	439	5.6	5.6	signal
329	Confusional State	4,754	5.6	5.8	signal
330	Poor Venous Access	303	5.6	5.6	signal
331	Musculoskeletal Disorder	559	5.5	5.6	signal
332	Oxygen Saturation Decreased	1,627	5.5	5.6	signal
333	Hepatotoxicity	638	5.4	5.5	signal
334	Neck Mass	81	5.4	5.4	signal
335	Hepatic Steatosis	532	5.4	5.4	signal
336	General Symptom	215	5.4	5.4	signal
337	Pulmonary Thrombosis	311	5.4	5.4	signal
338	Skin Abrasion	133	5.4	5.4	signal
339	Haematological Infection	66	5.4	5.4	signal
340	Therapeutic Response Decreased	1,710	5.4	5.4	signal
341	Drug Use Disorder	234	5.3	5.4	signal
342	Red Cell Distribution Width Increased	116	5.3	5.3	signal
343	Aphthous Ulcer	212	5.2	5.2	signal
344	Product Temperature Excursion Issue	131	5.2	5.2	signal
345	Terminal State	185	5.2	5.2	signal
346	Weight Fluctuation	286	5.2	5.2	signal
347	Breath Sounds Abnormal	135	5.2	5.2	signal
348	Tooth Infection	360	5.2	5.2	signal
349	Mouth Ulceration	573	5.2	5.2	signal
350	Intestinal Perforation	305	5.1	5.1	signal
351	Shoulder Arthroplasty	72	5.1	5.1	signal
352	Necrotising Fasciitis	95	5.1	5.1	signal
353	Drug Ineffective	35,434	5.1	6.9	signal
354	Respiratory Rate Increased	238	5.1	5.1	signal
355	Septic Shock	1,145	5.0	5.0	signal
356	Hypoaesthesia	3,959	5.0	5.1	signal
357	Tongue Disorder	192	5.0	5.0	signal
358	Abscess Limb	112	5.0	5.0	signal
359	Oral Herpes	506	4.9	4.9	signal
360	Ulcerative Keratitis	71	4.9	4.9	signal
361	Hypogammaglobulinaemia	166	4.9	4.9	signal
362	Pleurisy	152	4.8	4.8	signal
363	Gastric Infection	97	4.8	4.8	signal
364	Polymyalgia Rheumatica	78	4.7	4.7	signal
365	Dyspepsia	2,454	4.7	4.8	signal
366	Aspergillus Infection	162	4.7	4.7	signal
367	Mucormycosis	64	4.7	4.7	signal
368	Osteomyelitis	444	4.6	4.6	signal
369	Tongue Ulceration	83	4.6	4.6	signal
370	Granuloma	84	4.6	4.6	signal
371	Inflammatory Marker Increased	119	4.6	4.6	signal
372	Mass	334	4.5	4.5	signal
373	Cyst	296	4.5	4.5	signal
374	Tenderness	248	4.5	4.5	signal
375	Bronchiectasis	158	4.5	4.5	signal
376	Sensitivity To Weather Change	124	4.5	4.5	signal
377	Impaired Work Ability	508	4.5	4.5	signal
378	Dermatitis Allergic	294	4.4	4.5	signal
379	Off Label Use	20,459	4.4	5.2	signal
380	Large Intestine Perforation	162	4.4	4.4	signal
381	Dyslipidaemia	117	4.3	4.3	signal
382	Injection Site Reaction	1,568	4.3	4.3	signal
383	Tooth Abscess	233	4.3	4.3	signal
384	Toothache	412	4.3	4.3	signal
385	Animal Bite	60	4.3	4.3	signal
386	Tooth Disorder	508	4.3	4.3	signal
387	Endocarditis	116	4.3	4.3	signal
388	Lymphoproliferative Disorder	66	4.2	4.2	signal
389	Ocular Discomfort	243	4.2	4.2	signal
390	Skin Reaction	314	4.2	4.2	signal
391	Ligament Sprain	220	4.2	4.2	signal
392	Klebsiella Infection	112	4.2	4.2	signal
393	Asthma	2,497	4.2	4.3	signal
394	Uveitis	297	4.1	4.1	signal
395	Erysipelas	111	4.1	4.1	signal
396	Pneumocystis Jirovecii Pneumonia	219	4.1	4.1	signal
397	Pain In Extremity	6,435	4.1	4.3	signal
398	Abdominal Pain Upper	4,478	4.1	4.2	signal
399	Migraine	2,063	4.1	4.1	signal
400	Drug Specific Antibody Present	141	4.1	4.1	signal
401	Alanine Aminotransferase Increased	1,332	4.1	4.1	signal
402	Hepatic Fibrosis	74	4.1	4.1	signal
403	Generalised Oedema	266	4.1	4.1	signal
404	Cytomegalovirus Viraemia	94	4.0	4.0	signal
405	Glaucoma	410	4.0	4.0	signal
406	Enterococcal Infection	103	4.0	4.0	signal
407	Rash Pruritic	1,145	4.0	4.0	signal
408	Hyperkeratosis	117	4.0	4.0	signal
409	Thermal Burn	150	4.0	4.0	signal
410	Bronchitis	1,571	4.0	4.0	signal
411	Ear Pruritus	73	3.9	3.9	signal
412	Leukopenia	1,044	3.9	4.0	signal
413	Foot Fracture	397	3.9	3.9	signal
414	Osteopenia	318	3.9	3.9	signal
415	Bacterial Sepsis	68	3.9	3.9	signal
416	Back Disorder	339	3.9	3.9	signal
417	Aspartate Aminotransferase Increased	1,102	3.9	3.9	signal
418	Pyelonephritis	178	3.9	3.9	signal
419	Adverse Event	1,898	3.9	3.9	signal
420	Pyoderma Gangrenosum	73	3.8	3.8	signal
421	Femur Fracture	634	3.8	3.8	signal
422	Bedridden	267	3.8	3.8	signal
423	Staphylococcal Bacteraemia	88	3.8	3.8	signal
424	Cytomegalovirus Infection Reactivation	86	3.8	3.8	signal
425	Liver Function Test Abnormal	588	3.8	3.8	signal
426	Tendon Disorder	131	3.8	3.8	signal
427	Gastroenteritis Viral	363	3.8	3.8	signal
428	Chronic Sinusitis	75	3.8	3.8	signal
429	Vein Disorder	101	3.8	3.8	signal
430	Fluid Retention	1,007	3.7	3.7	signal
431	Fatigue	15,377	3.7	4.1	signal
432	Pneumonia	6,396	3.7	3.9	signal
433	Vasculitis	229	3.7	3.7	signal
434	Amnesia	1,273	3.7	3.7	signal
435	Muscular Weakness	2,185	3.6	3.7	signal
436	Bone Density Decreased	609	3.6	3.6	signal
437	Adverse Drug Reaction	1,710	3.6	3.6	signal
438	Pyrexia	6,600	3.6	3.7	signal
439	Anaphylactic Reaction	1,045	3.6	3.6	signal
440	Multiple Allergies	149	3.6	3.6	signal
441	Fungal Skin Infection	76	3.6	3.6	signal
442	Lymphocyte Count Increased	62	3.6	3.6	signal
443	Bacteraemia	223	3.6	3.6	signal
444	Gastric Disorder	659	3.5	3.6	signal
445	Fear Of Injection	132	3.5	3.5	signal
446	Candida Infection	315	3.5	3.5	signal
447	Malignant Melanoma	253	3.5	3.5	signal
448	Spinal Disorder	178	3.5	3.5	signal
449	Vaginal Infection	88	3.5	3.5	signal
450	Medication Error	1,030	3.5	3.5	signal
451	Encephalitis	128	3.5	3.5	signal
452	Skin Infection	206	3.5	3.5	signal
453	Spinal Compression Fracture	155	3.5	3.5	signal
454	Paranasal Sinus Discomfort	69	3.4	3.4	signal
455	Product Complaint	456	3.4	3.4	signal
456	Rash Erythematous	853	3.4	3.4	signal
457	Tooth Fracture	200	3.4	3.4	signal
458	Disseminated Intravascular Coagulation	255	3.4	3.4	signal
459	Pruritus	6,821	3.4	3.5	signal
460	Hyperaesthesia	149	3.4	3.4	signal
461	Photophobia	335	3.4	3.4	signal
462	Tendonitis	279	3.4	3.4	signal
463	Cystitis	573	3.4	3.4	signal
464	Tuberculosis	229	3.3	3.3	signal
465	Cellulitis	897	3.3	3.3	signal
466	Blood Pressure Increased	2,718	3.3	3.4	signal
467	Meningitis	118	3.3	3.3	signal
468	Immunosuppression	153	3.3	3.3	signal
469	Sleep Disorder Due To A General Medical Condition	285	3.3	3.3	signal
470	Anal Abscess	94	3.3	3.3	signal
471	Injection Site Inflammation	86	3.3	3.3	signal
472	Gait Disturbance	3,295	3.2	3.3	signal
473	Lymphoedema	118	3.2	3.2	signal
474	Insomnia	4,547	3.2	3.3	signal
475	Head Discomfort	300	3.2	3.2	signal
476	Oral Disorder	125	3.2	3.2	signal
477	Sinus Congestion	230	3.2	3.2	signal
478	Bone Disorder	312	3.2	3.2	signal
479	Secretion Discharge	209	3.2	3.2	signal
480	Limb Discomfort	522	3.2	3.2	signal
481	Thyroid Disorder	259	3.1	3.1	signal
482	Serum Ferritin Increased	88	3.1	3.1	signal
483	Gastroenteritis	244	3.1	3.1	signal
484	Eye Infection	187	3.1	3.1	signal
485	Cytopenia	198	3.1	3.1	signal
486	Tonsillitis	86	3.1	3.1	signal
487	Gastrooesophageal Reflux Disease	1,320	3.1	3.1	signal
488	Kidney Infection	320	3.0	3.1	signal
489	Post Procedural Infection	132	3.0	3.0	signal
490	Therapy Partial Responder	245	3.0	3.0	signal
491	Bacterial Infection	301	3.0	3.0	signal
492	Goitre	66	3.0	3.0	signal
493	Impaired Gastric Emptying	204	3.0	3.0	signal
494	Blindness Unilateral	225	3.0	3.0	signal
495	Ankylosing Spondylitis	208	3.0	3.0	signal
496	Oral Discomfort	222	3.0	3.0	signal
497	Enterocolitis	91	3.0	3.0	signal
498	Herpes Virus Infection	92	3.0	3.0	signal
499	Gingivitis	86	3.0	3.0	signal
500	Multiple Organ Dysfunction Syndrome	443	3.0	3.0	signal
501	Ecchymosis	109	3.0	3.0	signal
502	Arthropod Bite	116	2.9	3.0	signal
503	Oedema Peripheral	1,921	2.9	3.0	signal
504	Diverticulum	113	2.9	2.9	signal
505	Vitamin D Decreased	133	2.9	2.9	signal
506	Carpal Tunnel Syndrome	218	2.9	2.9	signal
507	Postoperative Wound Infection	104	2.9	2.9	signal
508	Headache	9,649	2.9	3.1	signal
509	Pseudomonas Infection	130	2.9	2.9	signal
510	Limb Operation	73	2.9	2.9	signal
511	Abscess	242	2.8	2.8	signal
512	Sarcoidosis	72	2.8	2.8	signal
513	White Blood Cell Count Increased	582	2.8	2.8	signal
514	Fracture	286	2.8	2.8	signal
515	Chest Pain	2,800	2.8	2.9	signal
516	Memory Impairment	2,073	2.8	2.8	signal
517	Hepatic Function Abnormal	557	2.8	2.8	signal
518	Diffuse Large B-cell Lymphoma	114	2.8	2.8	signal
519	Acute Respiratory Distress Syndrome	263	2.8	2.8	signal
520	Blindness	598	2.7	2.8	signal
521	Nerve Injury	162	2.7	2.7	signal
522	Cataract	860	2.7	2.7	signal
523	Transaminases Increased	320	2.7	2.7	signal
524	Subcutaneous Abscess	69	2.7	2.7	signal
525	Weight Decreased	3,987	2.7	2.7	signal
526	Pain In Jaw	404	2.7	2.7	signal
527	Limb Injury	385	2.7	2.7	signal
528	Pneumothorax	225	2.6	2.7	signal
529	Stress Fracture	77	2.6	2.6	signal
530	Sepsis	1,580	2.6	2.7	signal
531	Malaise	6,220	2.6	2.7	signal
532	Fungal Infection	471	2.6	2.6	signal
533	Skin Warm	82	2.6	2.6	signal
534	Umbilical Hernia	66	2.6	2.6	signal
535	Intervertebral Disc Degeneration	131	2.6	2.6	signal
536	Ankle Fracture	218	2.6	2.6	signal
537	Product Use In Unapproved Indication	3,423	2.6	2.7	signal
538	Urosepsis	128	2.6	2.6	signal
539	Photosensitivity Reaction	228	2.6	2.6	signal
540	Maternal Exposure Before Pregnancy	94	2.6	2.6	signal
541	Paraesthesia	2,175	2.6	2.6	signal
542	Vomiting	6,430	2.6	2.7	signal
543	Platelet Count Increased	179	2.6	2.6	signal
544	Hand Fracture	97	2.6	2.6	signal
545	Furuncle	108	2.5	2.5	signal
546	Cytomegalovirus Infection	227	2.5	2.5	signal
547	Nephrolithiasis	620	2.5	2.5	signal
548	Skin Mass	90	2.5	2.5	signal
549	Toe Amputation	69	2.5	2.5	signal
550	Staphylococcal Sepsis	67	2.5	2.5	signal
551	Multiple Fractures	223	2.5	2.5	signal
552	Organising Pneumonia	66	2.5	2.5	signal
553	Hernia	258	2.5	2.5	signal
554	Psoriasis	1,748	2.5	2.5	signal
555	Decreased Appetite	3,086	2.5	2.5	signal
556	Eye Disorder	435	2.5	2.5	signal
557	Frequent Bowel Movements	356	2.5	2.5	signal
558	Oropharyngeal Pain	1,223	2.5	2.5	signal
559	Quality Of Life Decreased	177	2.5	2.5	signal
560	Dry Eye	635	2.4	2.4	signal
561	Rash Maculo-papular	290	2.4	2.4	signal
562	Rhinitis	105	2.4	2.4	signal
563	Epstein-barr Virus Infection	81	2.4	2.4	signal
564	Altered State Of Consciousness	280	2.4	2.4	signal
565	Laboratory Test Abnormal	382	2.4	2.4	signal
566	Abdominal Pain	2,997	2.4	2.4	signal
567	Muscle Spasms	2,364	2.4	2.4	signal
568	Compression Fracture	67	2.4	2.4	signal
569	Spinal Osteoarthritis	113	2.4	2.4	signal
570	Lymphoma	198	2.4	2.4	signal
571	Musculoskeletal Discomfort	218	2.4	2.4	signal
572	Humerus Fracture	61	2.3	2.3	signal
573	Drug Effect Decreased	687	2.3	2.3	signal
574	Diabetes Mellitus	960	2.3	2.3	signal
575	Gingival Bleeding	171	2.3	2.3	signal
576	White Blood Cell Count Decreased	1,348	2.3	2.3	signal
577	Spinal Pain	145	2.3	2.3	signal
578	Dyspnoea	7,002	2.3	2.4	signal
579	Skin Atrophy	71	2.3	2.3	signal
580	Influenza	1,383	2.3	2.3	signal
581	Phlebitis	63	2.3	2.3	signal
582	Accident	146	2.3	2.3	signal
583	Back Pain	2,847	2.3	2.3	signal
584	Asthenia	4,602	2.3	2.3	signal
585	Needle Issue	350	2.3	2.3	signal
586	Underdose	887	2.3	2.3	signal
587	Visual Impairment	1,493	2.3	2.3	signal
588	Gastrointestinal Infection	108	2.3	2.3	signal
589	Diarrhoea	7,704	2.2	2.3	signal
590	Intervertebral Disc Protrusion	261	2.2	2.2	signal
591	Hypertriglyceridaemia	69	2.2	2.2	signal
592	Increased Tendency To Bruise	109	2.2	2.2	signal
593	Cataract Operation	70	2.2	2.2	signal
594	Spinal Fracture	235	2.2	2.2	signal
595	Rectal Haemorrhage	508	2.2	2.2	signal
596	Respiratory Tract Infection	304	2.2	2.2	signal
597	Decreased Immune Responsiveness	114	2.2	2.2	signal
598	Injection Site Extravasation	145	2.2	2.2	signal
599	Dental Caries	128	2.2	2.2	signal
600	Pharyngitis Streptococcal	125	2.1	2.1	signal
601	Oral Pain	258	2.1	2.1	signal
602	Haematemesis	291	2.1	2.1	signal
603	Hypocalcaemia	216	2.1	2.1	signal
604	Renal Cyst	91	2.1	2.1	signal
605	Blood Test Abnormal	160	2.1	2.1	signal
606	Conjunctivitis	209	2.1	2.1	signal
607	Groin Pain	100	2.1	2.1	signal
608	Tachycardia	996	2.1	2.1	signal
609	Meniscus Injury	69	2.1	2.1	signal
610	Heart Rate Increased	1,109	2.1	2.1	signal
611	Cholecystitis	133	2.1	2.1	signal
612	Depression	2,547	2.1	2.1	signal
613	Seasonal Allergy	156	2.1	2.1	signal
614	Productive Cough	522	2.1	2.1	signal
615	Urinary Tract Infection	1,875	2.0	2.1	signal
616	Rotator Cuff Syndrome	142	2.0	2.0	signal
617	Drug Ineffective For Unapproved Indication	613	2.0	2.1	signal
618	Skin Lesion	299	2.0	2.0	signal
619	Angiopathy	62	2.0	2.0	signal
620	Pelvic Fracture	85	2.0	2.0	signal
621	Tendon Rupture	135	2.0	2.0	signal
622	Muscle Strain	94	2.0	2.0	signal
623	Immune System Disorder	143	2.0	2.0	signal
624	Rales	63	2.0	2.0	signal
625	Polyp	71	2.0	2.0	signal
626	Scratch	112	2.0	2.0	signal
627	Pancreatitis	572	2.0	2.0	signal
628	Drug Effect Incomplete	398	2.0	2.0	signal
629	Staphylococcal Infection	357	2.0	2.0	signal
630	Syringe Issue	189	2.0	2.0	signal
631	Eye Haemorrhage	144	2.0	2.0	signal
632	Thrombocytopenia	1,191	2.0	2.0	no signal
633	Stent Placement	86	2.0	2.0	no signal
634	Vitamin D Deficiency	104	2.0	2.0	no signal
635	Emphysema	108	2.0	2.0	no signal
636	Fall	3,528	2.0	2.0	no signal
637	Nausea	8,355	2.0	2.0	no signal
638	Upper Limb Fracture	210	1.9	2.0	no signal
639	Lung Infection	164	1.9	1.9	no signal
640	Neutrophil Count Decreased	420	1.9	1.9	no signal
641	Hypothyroidism	330	1.9	1.9	no signal
642	Neutrophil Count Increased	106	1.9	1.9	no signal
643	Neuralgia	250	1.9	1.9	no signal
644	Deep Vein Thrombosis	672	1.9	1.9	no signal
645	Anaphylactic Shock	263	1.9	1.9	no signal
646	Lymphocyte Count Decreased	181	1.9	1.9	no signal
647	Colitis Ulcerative	454	1.9	1.9	no signal
648	Ascites	299	1.9	1.9	no signal
649	Dermatitis	209	1.9	1.9	no signal
650	Diplopia	262	1.9	1.9	no signal
651	Wrist Fracture	120	1.9	1.9	no signal
652	Dizziness	4,981	1.9	1.9	no signal
653	Swelling Of Eyelid	61	1.9	1.9	no signal
654	Gastric Ulcer	190	1.9	1.9	no signal
655	Sputum Discoloured	94	1.8	1.8	no signal
656	Lymphopenia	139	1.8	1.8	no signal
657	Red Blood Cell Count Decreased	280	1.8	1.8	no signal
658	Presyncope	236	1.8	1.8	no signal
659	Rib Fracture	199	1.8	1.8	no signal
660	Abdominal Distension	1,004	1.8	1.8	no signal
661	Erythema	1,982	1.8	1.8	no signal
662	Covid-19	1,702	1.8	1.8	no signal
663	Nasal Congestion	563	1.8	1.8	no signal
664	Lymphadenopathy	340	1.8	1.8	no signal
665	Coronavirus Infection	64	1.8	1.8	no signal
666	Pneumonitis	259	1.8	1.8	no signal
667	Respiratory Tract Congestion	152	1.8	1.8	no signal
668	Nerve Compression	88	1.8	1.8	no signal
669	Facial Paralysis	81	1.8	1.8	no signal
670	Cough	2,668	1.8	1.8	no signal
671	Deafness	247	1.8	1.8	no signal
672	Movement Disorder	304	1.7	1.8	no signal
673	Heart Rate Irregular	214	1.7	1.7	no signal
674	Neutropenia	1,275	1.7	1.8	no signal
675	Upper-airway Cough Syndrome	77	1.7	1.7	no signal
676	Pulmonary Embolism	894	1.7	1.7	no signal
677	Pharyngeal Oedema	146	1.7	1.7	no signal
678	Decubitus Ulcer	76	1.7	1.7	no signal
679	Cardiac Murmur	81	1.7	1.7	no signal
680	Skin Disorder	309	1.7	1.7	no signal
681	Rhinorrhoea	598	1.7	1.7	no signal
682	Oral Candidiasis	120	1.7	1.7	no signal
683	Thrombosis	740	1.7	1.7	no signal
684	Viral Infection	303	1.7	1.7	no signal
685	Neoplasm	105	1.7	1.7	no signal
686	Tinnitus	419	1.7	1.7	no signal
687	Feeling Hot	553	1.7	1.7	no signal
688	Aortic Aneurysm	69	1.7	1.7	no signal
689	Blood Creatinine Increased	588	1.7	1.7	no signal
690	Pharyngeal Swelling	86	1.7	1.7	no signal
691	Hyperhidrosis	1,153	1.7	1.7	no signal
692	Hiatus Hernia	116	1.7	1.7	no signal
693	Product Storage Error	773	1.7	1.7	no signal
694	Appendicitis	83	1.7	1.7	no signal
695	Stress	641	1.7	1.7	no signal
696	Cholelithiasis	290	1.6	1.6	no signal
697	Tumour Lysis Syndrome	77	1.6	1.6	no signal
698	Blood Potassium Increased	143	1.6	1.6	no signal
699	Hypertensive Crisis	98	1.6	1.6	no signal
700	Acute Respiratory Failure	167	1.6	1.6	no signal
701	Eye Pain	481	1.6	1.6	no signal
702	Faeces Soft	63	1.6	1.6	no signal
703	Exposure Via Skin Contact	196	1.6	1.6	no signal
704	Gingival Pain	69	1.6	1.6	no signal
705	Hip Fracture	277	1.6	1.6	no signal
706	Hepatic Cytolysis	105	1.6	1.6	no signal
707	Intentional Product Misuse	746	1.6	1.6	no signal
708	Low Density Lipoprotein Increased	66	1.6	1.6	no signal
709	Ovarian Cyst	86	1.6	1.6	no signal
710	Eye Inflammation	80	1.6	1.6	no signal
711	Hypotension	1,697	1.6	1.6	no signal
712	Haematocrit Decreased	169	1.6	1.6	no signal
713	Sleep Apnoea Syndrome	161	1.6	1.6	no signal
714	Renal Impairment	703	1.6	1.6	no signal
715	Throat Irritation	375	1.6	1.6	no signal
716	Pleural Effusion	509	1.5	1.6	no signal
717	Respiratory Failure	603	1.5	1.5	no signal
718	Embolism	69	1.5	1.5	no signal
719	Musculoskeletal Chest Pain	127	1.5	1.5	no signal
720	Hyperlipidaemia	98	1.5	1.5	no signal
721	Loss Of Consciousness	1,047	1.5	1.5	no signal
722	Neoplasm Malignant	544	1.5	1.5	no signal
723	Hypokalaemia	373	1.5	1.5	no signal
724	Flank Pain	76	1.5	1.5	no signal
725	Optic Neuritis	73	1.5	1.5	no signal
726	Burning Sensation	560	1.5	1.5	no signal
727	Haemoglobin Decreased	817	1.5	1.5	no signal
728	Pulmonary Congestion	105	1.5	1.5	no signal
729	Feeding Disorder	158	1.5	1.5	no signal
730	Device Related Infection	122	1.5	1.5	no signal
731	Atelectasis	76	1.5	1.5	no signal
732	Blood Iron Decreased	92	1.4	1.4	no signal
733	Hepatomegaly	77	1.4	1.4	no signal
734	Dry Throat	79	1.4	1.4	no signal
735	Platelet Count Decreased	825	1.4	1.4	no signal
736	Clostridium Difficile Infection	166	1.4	1.4	no signal
737	Haematuria	260	1.4	1.4	no signal
738	Chills	889	1.4	1.4	no signal
739	Posterior Reversible Encephalopathy Syndrome	72	1.4	1.4	no signal
740	Drug Resistance	192	1.4	1.4	no signal
741	Laceration	71	1.4	1.4	no signal
742	Epistaxis	552	1.4	1.4	no signal
743	Hypoxia	258	1.4	1.4	no signal
744	Neurotoxicity	127	1.4	1.4	no signal
745	Iron Deficiency Anaemia	67	1.4	1.4	no signal
746	Brain Neoplasm	67	1.3	1.4	no signal
747	Peritonitis	150	1.3	1.3	no signal
748	Cardio-respiratory Arrest	303	1.3	1.3	no signal
749	Anxiety	2,053	1.3	1.3	no signal
750	Product Quality Issue	966	1.3	1.3	no signal
751	Colon Cancer	107	1.3	1.3	no signal
752	Subarachnoid Haemorrhage	72	1.3	1.3	no signal
753	Myalgia	1,190	1.3	1.3	no signal
754	Therapy Interrupted	481	1.3	1.3	no signal
755	Skin Cancer	150	1.3	1.3	no signal
756	Syncope	696	1.3	1.3	no signal
757	Disease Progression	818	1.3	1.3	no signal
758	Internal Haemorrhage	79	1.3	1.3	no signal
759	Scar	118	1.3	1.3	no signal
760	Splenomegaly	80	1.3	1.3	no signal
761	Foetal Exposure During Pregnancy	555	1.3	1.3	no signal
762	Blood Triglycerides Increased	120	1.3	1.3	no signal
763	Local Swelling	119	1.2	1.2	no signal
764	Eosinophilia	117	1.2	1.2	no signal
765	Pancreatitis Acute	149	1.2	1.2	no signal
766	Coma	318	1.2	1.2	no signal
767	Gastrointestinal Pain	73	1.2	1.2	no signal
768	Dysphonia	387	1.2	1.2	no signal
769	Haemorrhoids	129	1.2	1.2	no signal
770	Hyperbilirubinaemia	68	1.2	1.2	no signal
771	Proteinuria	124	1.2	1.2	no signal
772	Bronchospasm	93	1.2	1.2	no signal
773	Peripheral Coldness	89	1.2	1.2	no signal
774	Cerebral Infarction	156	1.2	1.2	no signal
775	Swelling Face	414	1.2	1.2	no signal
776	Bladder Disorder	63	1.2	1.2	no signal
777	Aphonia	88	1.2	1.2	no signal
778	Angina Pectoris	182	1.2	1.2	no signal
779	Colitis	237	1.2	1.2	no signal
780	Atrial Fibrillation	606	1.1	1.2	no signal
781	Haematoma	161	1.1	1.1	no signal
782	Pancytopenia	343	1.1	1.1	no signal
783	Squamous Cell Carcinoma	58	1.1	1.1	no signal
784	Blood Urine Present	117	1.1	1.1	no signal
785	Device Malfunction	411	1.1	1.1	no signal
786	Gastritis	159	1.1	1.1	no signal
787	Myelodysplastic Syndrome	87	1.1	1.1	no signal
788	Abdominal Pain Lower	152	1.1	1.1	no signal
789	Thrombotic Microangiopathy	58	1.1	1.1	no signal
790	Diarrhoea Haemorrhagic	56	1.1	1.1	no signal
791	Pulmonary Oedema	268	1.1	1.1	no signal
792	Temperature Intolerance	61	1.1	1.1	no signal
793	Surgery	343	1.1	1.1	no signal
794	Sars-cov-2 Test Positive	79	1.1	1.1	no signal
795	Illness	594	1.1	1.1	no signal
796	Hepatocellular Injury	84	1.1	1.1	no signal
797	Gout	106	1.1	1.1	no signal
798	Agranulocytosis	109	1.1	1.1	no signal
799	Scab	66	1.1	1.1	no signal
800	Swollen Tongue	181	1.1	1.1	no signal
801	Cardiovascular Disorder	148	1.1	1.1	no signal
802	Skin Discolouration	263	1.1	1.1	no signal
803	Encephalopathy	139	1.0	1.0	no signal
804	Clostridium Difficile Colitis	60	1.0	1.0	no signal
805	Tooth Extraction	70	1.0	1.0	no signal
806	Renal Disorder	262	1.0	1.0	no signal
807	Dyspnoea Exertional	210	1.0	1.0	no signal
808	Gamma-glutamyltransferase Increased	124	1.0	1.0	no signal
809	Renal Failure	740	1.0	1.0	no signal
810	Shock	126	1.0	1.0	no signal
811	Product Administration Error	110	1.0	1.0	no signal
812	Lung Neoplasm Malignant	227	1.0	1.0	no signal
813	Restless Legs Syndrome	100	1.0	1.0	no signal
814	Wrong Technique In Device Usage Process	251	1.0	1.0	no signal
815	Petechiae	57	1.0	1.0	no signal
816	Incorrect Product Administration Duration	111	1.0	1.0	no signal
817	Leukocytosis	98	1.0	1.0	no signal
818	Full Blood Count Abnormal	57	1.0	1.0	no signal
819	Skin Fissures	102	1.0	1.0	no signal
820	Device Issue	471	1.0	1.0	no signal
821	Diabetes Mellitus Inadequate Control	95	1.0	1.0	no signal
822	Breast Cancer	504	1.0	1.0	no signal
823	Sneezing	119	1.0	1.0	no signal
824	Product Preparation Error	110	1.0	1.0	no signal
825	Gallbladder Disorder	95	1.0	1.0	no signal
826	Cardiac Failure	426	1.0	1.0	no signal
827	Myocardial Infarction	932	1.0	1.0	no signal
828	Spinal Operation	64	1.0	1.0	no signal
829	Blood Pressure Decreased	348	1.0	1.0	no signal
830	Blood Bilirubin Increased	142	1.0	1.0	no signal
831	Motor Dysfunction	53	1.0	1.0	no signal
832	Disease Recurrence	249	1.0	1.0	no signal
833	Hunger	70	1.0	1.0	no signal
834	Premature Delivery	83	1.0	1.0	no signal
835	Mucosal Inflammation	135	1.0	1.0	no signal
836	Haemoptysis	144	1.0	1.0	no signal
837	Head Injury	162	0.9	0.9	no signal
838	Post Procedural Complication	98	0.9	0.9	no signal
839	Sensory Disturbance	82	0.9	0.9	no signal
840	Throat Tightness	136	0.9	0.9	no signal
841	Product Dose Omission Issue	1,431	0.9	0.9	no signal
842	Chronic Obstructive Pulmonary Disease	262	0.9	0.9	no signal
843	Injection Site Pruritus	334	0.9	0.9	no signal
844	Hot Flush	377	0.9	0.9	no signal
845	Retching	106	0.9	0.9	no signal
846	Ear Discomfort	51	0.9	0.9	no signal
847	Constipation	1,069	0.9	0.9	no signal
848	Ischaemic Stroke	88	0.9	0.9	no signal
849	Pruritus Generalised	108	0.9	0.9	no signal
850	Muscle Tightness	79	0.9	0.9	no signal
851	Knee Operation	47	0.9	0.9	no signal
852	Pulmonary Hypertension	101	0.9	0.9	no signal
853	Injection Site Rash	146	0.9	0.9	no signal
854	Haematochezia	265	0.9	0.9	no signal
855	Polyneuropathy	57	0.9	0.9	no signal
856	Vertigo	292	0.9	0.9	no signal
857	Pericardial Effusion	110	0.9	0.9	no signal
858	Renal Tubular Necrosis	47	0.9	0.9	no signal
859	Chest Discomfort	487	0.9	0.9	no signal
860	Eye Discharge	48	0.9	0.9	no signal
861	Blood Alkaline Phosphatase Increased	116	0.9	0.9	no signal
862	Crying	170	0.9	0.9	no signal
863	Anaemia	889	0.9	0.9	no signal
864	Impaired Quality Of Life	67	0.9	0.9	no signal
865	Drug Effective For Unapproved Indication	136	0.9	0.9	no signal
866	Tachypnoea	63	0.9	0.9	no signal
867	Product Dispensing Error	101	0.9	0.9	no signal
868	Palpitations	539	0.9	0.9	no signal
869	Supraventricular Tachycardia	44	0.8	0.8	no signal
870	Bone Marrow Failure	94	0.8	0.8	no signal
871	Myocarditis	52	0.8	0.8	no signal
872	Micturition Urgency	52	0.8	0.8	no signal
873	Therapy Cessation	233	0.8	0.8	no signal
874	Renal Pain	48	0.8	0.8	no signal
875	Acute Myocardial Infarction	134	0.8	0.8	no signal
876	Blood Urea Increased	75	0.8	0.8	no signal
877	Haemorrhage	465	0.8	0.8	no signal
878	Somnolence	891	0.8	0.8	no signal
879	Incorrect Product Storage	59	0.8	0.8	no signal
880	Hypoacusis	189	0.8	0.8	no signal
881	Feeling Cold	121	0.8	0.8	no signal
882	Angioedema	191	0.8	0.8	no signal
883	Hospitalisation	658	0.8	0.8	no signal
884	Breast Pain	46	0.8	0.8	no signal
885	Cholecystectomy	49	0.8	0.8	no signal
886	Cardiac Disorder	405	0.8	0.8	no signal
887	Thyroid Cancer	52	0.8	0.8	no signal
888	Acute Hepatic Failure	58	0.8	0.8	no signal
889	Middle Insomnia	79	0.8	0.8	no signal
890	Influenza Like Illness	349	0.8	0.8	no signal
891	Overdose	914	0.8	0.8	no signal
892	Lacrimation Increased	126	0.8	0.8	no signal
893	Acute Kidney Injury	640	0.8	0.8	no signal
894	Respiratory Distress	116	0.8	0.8	no signal
895	Product Prescribing Error	98	0.8	0.8	no signal
896	Cerebrovascular Accident	703	0.8	0.8	no signal
897	Treatment Noncompliance	224	0.8	0.8	no signal
898	Brain Oedema	52	0.8	0.8	no signal
899	Oesophagitis	45	0.8	0.8	no signal
900	Transient Ischaemic Attack	139	0.8	0.8	no signal
901	Dysstasia	120	0.8	0.8	no signal
902	Aspiration	44	0.7	0.7	no signal
903	Osteonecrosis	134	0.7	0.7	no signal
904	Sinus Disorder	80	0.7	0.7	no signal
905	Cerebral Haemorrhage	144	0.7	0.7	no signal
906	Dementia	112	0.7	0.7	no signal
907	Nervous System Disorder	124	0.7	0.7	no signal
908	Neuropathy Peripheral	374	0.7	0.7	no signal
909	Urinary Incontinence	117	0.7	0.7	no signal
910	Melaena	86	0.7	0.7	no signal
911	Blood Creatine Phosphokinase Increased	114	0.7	0.7	no signal
912	Blood Lactate Dehydrogenase Increased	62	0.7	0.7	no signal
913	Ovarian Cancer	36	0.7	0.7	no signal
914	Body Height Decreased	42	0.7	0.7	no signal
915	Injection Site Discolouration	48	0.7	0.7	no signal
916	Pneumonia Aspiration	96	0.7	0.7	no signal
917	Pelvic Pain	70	0.7	0.7	no signal
918	Arrhythmia	183	0.7	0.7	no signal
919	Acne	293	0.7	0.7	no signal
920	Bone Pain	225	0.7	0.7	no signal
921	Poor Quality Sleep	82	0.7	0.7	no signal
922	Intraocular Pressure Increased	49	0.7	0.7	no signal
923	Pallor	104	0.7	0.7	no signal
924	Vision Blurred	519	0.7	0.7	no signal
925	Lip Swelling	126	0.7	0.7	no signal
926	Pulmonary Arterial Hypertension	55	0.7	0.7	no signal
927	Hepatic Failure	114	0.7	0.7	no signal
928	Brain Fog	55	0.7	0.7	no signal
929	Injection Site Bruising	293	0.7	0.7	no signal
930	Multi-organ Failure	65	0.7	0.7	no signal
931	Rebound Effect	42	0.7	0.7	no signal
932	Feeling Abnormal	888	0.7	0.7	no signal
933	Activities Of Daily Living Impaired	74	0.7	0.7	no signal
934	Feeling Jittery	70	0.7	0.7	no signal
935	Sudden Death	39	0.7	0.7	no signal
936	Injection Site Erythema	450	0.7	0.7	no signal
937	Emotional Disorder	113	0.7	0.7	no signal
938	Nocturia	44	0.7	0.7	no signal
939	Mitral Valve Incompetence	41	0.7	0.7	no signal
940	Intentional Dose Omission	99	0.7	0.7	no signal
941	Paraesthesia Oral	52	0.7	0.7	no signal
942	Macular Degeneration	43	0.7	0.7	no signal
943	Tremor	598	0.7	0.7	no signal
944	Retinal Detachment	33	0.7	0.7	no signal
945	Ocular Hyperaemia	165	0.7	0.7	no signal
946	Aphasia	106	0.6	0.6	no signal
947	Myelosuppression	119	0.6	0.6	no signal
948	Injection Site Swelling	263	0.6	0.6	no signal
949	Dysphagia	328	0.6	0.6	no signal
950	Blood Potassium Decreased	104	0.6	0.6	no signal
951	Cardiogenic Shock	49	0.6	0.6	no signal
952	Bone Loss	52	0.6	0.6	no signal
953	Dysuria	126	0.6	0.6	no signal
954	Flushing	348	0.6	0.6	no signal
955	Complication Associated With Device	45	0.6	0.6	no signal
956	Injection Site Induration	44	0.6	0.6	no signal
957	Vitreous Floaters	33	0.6	0.6	no signal
958	Accidental Exposure To Product	338	0.6	0.6	no signal
959	Coagulopathy	56	0.6	0.6	no signal
960	Product Dose Omission	223	0.6	0.6	no signal
961	Drug Interaction	525	0.6	0.6	no signal
962	Unevaluable Event	250	0.6	0.6	no signal
963	Increased Appetite	62	0.6	0.6	no signal
964	Drug Reaction With Eosinophilia And Systemic Symptoms	84	0.6	0.6	no signal
965	Cold Sweat	58	0.6	0.6	no signal
966	Blood Pressure Abnormal	65	0.6	0.6	no signal
967	Chromaturia	74	0.6	0.6	no signal
968	Eczema	164	0.6	0.6	no signal
969	Ileus	40	0.6	0.6	no signal
970	Premature Baby	98	0.6	0.6	no signal
971	Malnutrition	36	0.6	0.6	no signal
972	Glomerular Filtration Rate Decreased	39	0.6	0.6	no signal
973	Erythema Multiforme	30	0.6	0.6	no signal
974	Cardiac Arrest	266	0.6	0.6	no signal
975	Abasia	80	0.6	0.6	no signal
976	Arteriosclerosis	30	0.6	0.6	no signal
977	Status Epilepticus	36	0.6	0.6	no signal
978	Muscle Atrophy	40	0.6	0.6	no signal
979	Bradycardia	169	0.6	0.6	no signal
980	Eye Swelling	117	0.6	0.6	no signal
981	Flatulence	178	0.6	0.6	no signal
982	Cyanosis	49	0.6	0.6	no signal
983	Hyperglycaemia	112	0.6	0.6	no signal
984	Cardiac Failure Congestive	249	0.6	0.6	no signal
985	Urinary Retention	102	0.6	0.6	no signal
986	Product Dose Omission In Error	82	0.6	0.6	no signal
987	Sluggishness	31	0.6	0.6	no signal
988	Injection Site Urticaria	74	0.6	0.6	no signal
989	Febrile Neutropenia	202	0.6	0.6	no signal
990	Cholestasis	58	0.6	0.6	no signal
991	Gastric Haemorrhage	35	0.6	0.6	no signal
992	Hypoaesthesia Oral	45	0.6	0.6	no signal
993	Breast Cancer Stage I	28	0.5	0.5	no signal
994	Device Failure	45	0.5	0.5	no signal
995	Speech Disorder	155	0.5	0.5	no signal
996	Haematotoxicity	27	0.5	0.5	no signal
997	Panic Attack	106	0.5	0.5	no signal
998	Balance Disorder	249	0.5	0.5	no signal
999	Gastrointestinal Haemorrhage	241	0.5	0.5	no signal
1000	Leukaemia	27	0.5	0.5	no signal
1001	Procedural Pain	78	0.5	0.5	no signal
1002	Eye Irritation	157	0.5	0.5	no signal
1003	Blood Thyroid Stimulating Hormone Increased	26	0.5	0.5	no signal
1004	Intestinal Obstruction	105	0.5	0.5	no signal
1005	Metastases To Liver	49	0.5	0.5	no signal
1006	Death	2,405	0.5	0.5	no signal
1007	Myocardial Ischaemia	32	0.5	0.5	no signal
1008	Pollakiuria	116	0.5	0.5	no signal
1009	Abortion Spontaneous	112	0.5	0.5	no signal
1010	Paralysis	40	0.5	0.5	no signal
1011	Therapeutic Response Shortened	88	0.5	0.5	no signal
1012	Dehydration	368	0.5	0.5	no signal
1013	Fistula	31	0.5	0.5	no signal
1014	Wrong Technique In Product Usage Process	547	0.5	0.5	no signal
1015	Eye Pruritus	89	0.5	0.5	no signal
1016	Inappropriate Schedule Of Product Administration	476	0.5	0.5	no signal
1017	Ventricular Extrasystoles	28	0.5	0.5	no signal
1018	Jaundice	72	0.5	0.5	no signal
1019	No Therapeutic Response	33	0.5	0.5	no signal
1020	Mood Swings	85	0.5	0.5	no signal
1021	Inflammatory Bowel Disease	26	0.5	0.5	no signal
1022	Hypoglycaemia	128	0.5	0.5	no signal
1023	Hypokinesia	38	0.5	0.5	no signal
1024	Nephropathy Toxic	29	0.5	0.5	no signal
1025	Injury Associated With Device	52	0.5	0.5	no signal
1026	Hyponatraemia	145	0.5	0.5	no signal
1027	Cardiomyopathy	38	0.5	0.5	no signal
1028	Nephropathy	24	0.5	0.5	no signal
1029	Device Mechanical Issue	33	0.5	0.5	no signal
1030	Incontinence	27	0.5	0.5	no signal
1031	Hemiparesis	43	0.5	0.5	no signal
1032	Decreased Activity	27	0.5	0.5	no signal
1033	Seizure	289	0.5	0.5	no signal
1034	Thinking Abnormal	47	0.5	0.5	no signal
1035	Obstructive Airways Disorder	28	0.5	0.5	no signal
1036	Subdural Haematoma	36	0.5	0.5	no signal
1037	Gastric Cancer	64	0.5	0.5	no signal
1038	Skin Haemorrhage	36	0.5	0.5	no signal
1039	Hyperthyroidism	36	0.5	0.5	no signal
1040	Blood Calcium Decreased	28	0.5	0.5	no signal
1041	Ventricular Tachycardia	41	0.5	0.5	no signal
1042	Dermatitis Contact	28	0.5	0.5	no signal
1043	Poor Quality Product Administered	25	0.5	0.5	no signal
1044	Nervousness	128	0.4	0.4	no signal
1045	Osteonecrosis Of Jaw	60	0.4	0.4	no signal
1046	Pancreatic Carcinoma	69	0.4	0.4	no signal
1047	Faeces Discoloured	51	0.4	0.4	no signal
1048	Sinus Tachycardia	33	0.4	0.4	no signal
1049	Glycosylated Haemoglobin Increased	58	0.4	0.4	no signal
1050	Depressed Mood	121	0.4	0.4	no signal
1051	Lethargy	132	0.4	0.4	no signal
1052	Gastrointestinal Carcinoma	21	0.4	0.4	no signal
1053	Toxic Skin Eruption	23	0.4	0.4	no signal
1054	Acute Myeloid Leukaemia	35	0.4	0.4	no signal
1055	Device Difficult To Use	148	0.4	0.4	no signal
1056	Full Blood Count Decreased	45	0.4	0.4	no signal
1057	Intercepted Product Preparation Error	27	0.4	0.4	no signal
1058	Choking	43	0.4	0.4	no signal
1059	Mood Altered	60	0.4	0.4	no signal
1060	Small Intestinal Obstruction	27	0.4	0.4	no signal
1061	Dry Skin	288	0.4	0.4	no signal
1062	Drug Level Increased	36	0.4	0.4	no signal
1063	Hypothermia	22	0.4	0.4	no signal
1064	Blood Glucose Increased	407	0.4	0.4	no signal
1065	Toxicity To Various Agents	361	0.4	0.4	no signal
1066	Eyelid Oedema	25	0.4	0.4	no signal
1067	Hepatitis C	26	0.4	0.4	no signal
1068	Face Oedema	36	0.4	0.4	no signal
1069	Amenorrhoea	35	0.4	0.4	no signal
1070	Thirst	37	0.4	0.4	no signal
1071	Drug Dependence	337	0.4	0.4	no signal
1072	Ventricular Fibrillation	23	0.4	0.4	no signal
1073	Mental Disorder	90	0.4	0.4	no signal
1074	Cognitive Disorder	95	0.4	0.4	no signal
1075	Coronary Artery Occlusion	28	0.4	0.4	no signal
1076	Upper Gastrointestinal Haemorrhage	34	0.4	0.4	no signal
1077	Hereditary Angioedema	21	0.4	0.4	no signal
1078	Multiple Sclerosis	96	0.4	0.4	no signal
1079	Chronic Kidney Disease	153	0.4	0.4	no signal
1080	Brain Injury	20	0.4	0.4	no signal
1081	Hypophagia	50	0.4	0.4	no signal
1082	Fear	53	0.4	0.4	no signal
1083	Malignant Neoplasm Progression	199	0.4	0.4	no signal
1084	Rash Generalised	51	0.4	0.4	no signal
1085	Rash Macular	67	0.4	0.4	no signal
1086	Electrolyte Imbalance	22	0.4	0.4	no signal
1087	Mental Status Changes	53	0.4	0.4	no signal
1088	Muscle Twitching	44	0.4	0.4	no signal
1089	Pain Of Skin	51	0.3	0.3	no signal
1090	Lactic Acidosis	60	0.3	0.3	no signal
1091	Device Occlusion	26	0.3	0.3	no signal
1092	Metabolic Acidosis	59	0.3	0.3	no signal
1093	Blood Sodium Decreased	35	0.3	0.3	no signal
1094	Hyperkalaemia	64	0.3	0.3	no signal
1095	Device Dislocation	79	0.3	0.3	no signal
1096	Hepatic Encephalopathy	17	0.3	0.3	no signal
1097	Hepatic Cancer	44	0.3	0.3	no signal
1098	Central Nervous System Lesion	25	0.3	0.3	no signal
1099	Electrocardiogram Qt Prolonged	65	0.3	0.3	no signal
1100	Visual Acuity Reduced	60	0.3	0.3	no signal
1101	Suicidal Ideation	164	0.3	0.3	no signal
1102	Hypersomnia	51	0.3	0.3	no signal
1103	Injection Site Haemorrhage	141	0.3	0.3	no signal
1104	Initial Insomnia	18	0.3	0.3	no signal
1105	Therapy Change	17	0.3	0.3	no signal
1106	Sinus Bradycardia	17	0.3	0.3	no signal
1107	Injection Site Mass	64	0.3	0.3	no signal
1108	Toxic Epidermal Necrolysis	26	0.3	0.3	no signal
1109	Post Procedural Haemorrhage	20	0.3	0.3	no signal
1110	Blood Glucose Abnormal	31	0.3	0.3	no signal
1111	Coronary Artery Disease	51	0.3	0.3	no signal
1112	Hallucination	124	0.3	0.3	no signal
1113	Prostate Cancer	134	0.3	0.3	no signal
1114	Product Packaging Quantity Issue	18	0.3	0.3	no signal
1115	Injection Site Discomfort	17	0.3	0.3	no signal
1116	Injection Site Pain	499	0.3	0.3	no signal
1117	Eating Disorder	35	0.3	0.3	no signal
1118	Circulatory Collapse	28	0.3	0.3	no signal
1119	Disorientation	65	0.3	0.3	no signal
1120	Fluid Overload	24	0.3	0.3	no signal
1121	Depressed Level Of Consciousness	64	0.3	0.3	no signal
1122	Respiratory Arrest	45	0.3	0.3	no signal
1123	Menorrhagia	32	0.3	0.3	no signal
1124	Device Breakage	63	0.3	0.3	no signal
1125	Abortion Induced	15	0.3	0.3	no signal
1126	Apathy	23	0.3	0.3	no signal
1127	International Normalised Ratio Increased	45	0.3	0.3	no signal
1128	Metastases To Lung	18	0.3	0.3	no signal
1129	Rash Papular	35	0.3	0.3	no signal
1130	Hair Texture Abnormal	21	0.3	0.3	no signal
1131	Device Use Error	53	0.3	0.3	no signal
1132	Orthostatic Hypotension	27	0.3	0.3	no signal
1133	Drug Dose Omission	258	0.3	0.3	no signal
1134	Dysgeusia	114	0.3	0.3	no signal
1135	Circumstance Or Information Capable Of Leading To Medication Error	51	0.3	0.3	no signal
1136	Hypomagnesaemia	21	0.3	0.3	no signal
1137	Injection Site Warmth	31	0.3	0.3	no signal
1138	Blood Glucose Decreased	72	0.3	0.3	no signal
1139	Skin Irritation	66	0.3	0.3	no signal
1140	Tooth Loss	30	0.3	0.3	no signal
1141	Stevens-johnson Syndrome	32	0.3	0.3	no signal
1142	Skeletal Injury	15	0.3	0.3	no signal
1143	Blood Count Abnormal	22	0.3	0.3	no signal
1144	Infusion Site Pain	18	0.3	0.3	no signal
1145	Hypotonia	14	0.3	0.3	no signal
1146	Device Leakage	59	0.3	0.3	no signal
1147	Psychotic Disorder	41	0.3	0.3	no signal
1148	Respiratory Depression	17	0.3	0.3	no signal
1149	Inappropriate Antidiuretic Hormone Secretion	14	0.3	0.3	no signal
1150	Blood Glucose Fluctuation	15	0.3	0.3	no signal
1151	Dizziness Postural	13	0.2	0.2	no signal
1152	Coordination Abnormal	19	0.2	0.2	no signal
1153	Agitation	99	0.2	0.2	no signal
1154	Injection Site Irritation	17	0.2	0.2	no signal
1155	Ataxia	16	0.2	0.2	no signal
1156	Haemorrhage Intracranial	20	0.2	0.2	no signal
1157	Vaginal Haemorrhage	56	0.2	0.2	no signal
1158	Breast Cancer Metastatic	14	0.2	0.2	no signal
1159	Ejection Fraction Decreased	20	0.2	0.2	no signal
1160	Ageusia	32	0.2	0.2	no signal
1161	Caesarean Section	15	0.2	0.2	no signal
1162	Neoplasm Progression	44	0.2	0.2	no signal
1163	Dysarthria	47	0.2	0.2	no signal
1164	Anger	42	0.2	0.2	no signal
1165	Mental Impairment	30	0.2	0.2	no signal
1166	Product Prescribing Issue	25	0.2	0.2	no signal
1167	Tubulointerstitial Nephritis	23	0.2	0.2	no signal
1168	Delusion	19	0.2	0.2	no signal
1169	Breast Cancer Female	33	0.2	0.2	no signal
1170	Metastases To Bone	20	0.2	0.2	no signal
1171	Insurance Issue	18	0.2	0.2	no signal
1172	Plasma Cell Myeloma	47	0.2	0.2	no signal
1173	Salivary Hypersecretion	12	0.2	0.2	no signal
1174	Skin Exfoliation	99	0.2	0.2	no signal
1175	Product Packaging Issue	11	0.2	0.2	no signal
1176	Irritability	71	0.2	0.2	no signal
1177	Accidental Overdose	43	0.2	0.2	no signal
1178	Accidental Underdose	17	0.2	0.2	no signal
1179	Injection Site Haematoma	17	0.2	0.2	no signal
1180	Product Administered At Inappropriate Site	21	0.2	0.2	no signal
1181	Transfusion	12	0.2	0.2	no signal
1182	Parkinsonism	11	0.2	0.2	no signal
1183	Hospice Care	11	0.2	0.2	no signal
1184	Sedation	29	0.2	0.2	no signal
1185	Generalised Tonic-clonic Seizure	18	0.2	0.2	no signal
1186	Bladder Cancer	65	0.2	0.2	no signal
1187	Paranoia	18	0.2	0.2	no signal
1188	Dyskinesia	42	0.2	0.2	no signal
1189	Anosmia	15	0.2	0.2	no signal
1190	Myoclonus	12	0.2	0.2	no signal
1191	Diabetic Ketoacidosis	24	0.2	0.2	no signal
1192	Therapeutic Response Unexpected	45	0.2	0.2	no signal
1193	Vaginal Discharge	10	0.2	0.2	no signal
1194	Peritonitis Bacterial	10	0.2	0.2	no signal
1195	Dialysis	14	0.2	0.2	no signal
1196	Unresponsive To Stimuli	25	0.2	0.2	no signal
1197	Cardiomegaly	12	0.2	0.2	no signal
1198	Renal Injury	28	0.2	0.2	no signal
1199	Renal Failure Acute	40	0.2	0.2	no signal
1200	Skin Burning Sensation	66	0.2	0.2	no signal
1201	Bipolar Disorder	10	0.2	0.2	no signal
1202	Menstruation Irregular	24	0.2	0.2	no signal
1203	Restlessness	33	0.2	0.2	no signal
1204	Rhabdomyolysis	37	0.2	0.2	no signal
1205	Disturbance In Attention	48	0.2	0.2	no signal
1206	Incorrect Dose Administered	197	0.2	0.2	no signal
1207	Poisoning	11	0.2	0.2	no signal
1208	Oesophageal Carcinoma	25	0.2	0.2	no signal
1209	Meningioma	12	0.1	0.1	no signal
1210	Drug Administration Error	25	0.1	0.1	no signal
1211	Impaired Driving Ability	9	0.1	0.1	no signal
1212	Drug Effect Less Than Expected	11	0.1	0.1	no signal
1213	Menstruation Delayed	8	0.1	0.1	no signal
1214	Renal Cancer	36	0.1	0.1	no signal
1215	Mania	12	0.1	0.1	no signal
1216	Prostatic Specific Antigen Increased	10	0.1	0.1	no signal
1217	Hair Colour Changes	9	0.1	0.1	no signal
1218	End Stage Renal Disease	13	0.1	0.1	no signal
1219	Genital Haemorrhage	9	0.1	0.1	no signal
1220	Device Use Issue	12	0.1	0.1	no signal
1221	Suicide Attempt	42	0.1	0.1	no signal
1222	Device Delivery System Issue	18	0.1	0.1	no signal
1223	Drug Level Decreased	7	0.1	0.1	no signal
1224	Muscle Rigidity	8	0.1	0.1	no signal
1225	Personality Change	6	0.1	0.1	no signal
1226	Grand Mal Convulsion	6	0.1	0.1	no signal
1227	Convulsion	37	0.1	0.1	no signal
1228	Eructation	12	0.1	0.1	no signal
1229	Hallucination, Auditory	10	0.1	0.1	no signal
1230	Metastases To Central Nervous System	8	0.1	0.1	no signal
1231	Inability To Afford Medication	6	0.1	0.1	no signal
1232	Aggression	30	0.1	0.1	no signal
1233	Euphoric Mood	6	0.1	0.1	no signal
1234	Product Use Complaint	9	0.1	0.1	no signal
1235	Dystonia	11	0.1	0.1	no signal
1236	Nightmare	19	0.1	0.1	no signal
1237	Expired Product Administered	18	0.1	0.1	no signal
1238	Inappropriate Schedule Of Drug Administration	39	0.1	0.1	no signal
1239	Serotonin Syndrome	10	0.1	0.1	no signal
1240	Withdrawal Syndrome	22	0.1	0.1	no signal
1241	Abnormal Behaviour	20	0.1	0.1	no signal
1242	Schizophrenia	6	0.1	0.1	no signal
1243	Eyelid Ptosis	5	0.1	0.1	no signal
1244	Product Odour Abnormal	5	0.1	0.1	no signal
1245	Emotional Distress	58	0.1	0.1	no signal
1246	Metrorrhagia	8	0.1	0.1	no signal
1247	Dysmenorrhoea	6	0.1	0.1	no signal
1248	Product Physical Issue	9	0.1	0.1	no signal
1249	Incorrect Dose Administered By Device	11	0.1	0.1	no signal
1250	Madarosis	5	0.1	0.1	no signal
1251	Product Availability Issue	9	0.1	0.1	no signal
1252	Intentional Self-injury	8	0.1	0.1	no signal
1253	Hallucination, Visual	8	0.1	0.1	no signal
1254	Complication Of Device Insertion	7	0.1	0.1	no signal
1255	Product Taste Abnormal	5	0.1	0.1	no signal
1256	Injection Site Nodule	4	0.1	0.1	no signal
1257	Psychomotor Hyperactivity	6	0.1	0.1	no signal
1258	Drug Dispensing Error	5	0.1	0.1	no signal
1259	Application Site Pain	7	0.1	0.1	no signal
1260	Affect Lability	3	0.1	0.1	no signal
1261	Product Substitution Issue	17	0.1	0.1	no signal
1262	Dermatitis Atopic	13	0.0	0.0	no signal
1263	Incorrect Drug Administration Duration	7	0.0	0.0	no signal
1264	Libido Decreased	3	0.0	0.0	no signal
1265	Drug Prescribing Error	4	0.0	0.0	no signal
1266	Extra Dose Administered	7	0.0	0.0	no signal
1267	Palmar-plantar Erythrodysaesthesia Syndrome	4	0.0	0.0	no signal
1268	Incorrect Route Of Drug Administration	6	0.0	0.0	no signal
1269	Multiple Sclerosis Relapse	10	0.0	0.0	no signal
1270	Intentional Drug Misuse	3	0.0	0.0	no signal
1271	Gynaecomastia	4	0.0	0.0	no signal
1272	Drug Abuse	10	0.0	0.0	no signal
1273	Colorectal Cancer	5	0.0	0.0	no signal
1274	Drug Withdrawal Syndrome	9	0.0	0.0	no signal
1275	Completed Suicide	8	0.0	0.0	no signal
1276	Drug Dose Omission By Device	7	0.0	0.0	no signal