Reaction

Blood Sodium Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,675 reports · 79 co-occurring drugs

As of the last recalculation, Blood Sodium Increased appears in 2,675 FAERS reports alongside 79 co-occurring drug terms. The strongest observed disproportionality signal is TOLVAPTAN (PRR 92.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Tolvaptan	162	92.3	93.3
Lithium Carbonate	55	25.7	25.8
Atropine	19	18.0	18.0
Atropine Sulfate	21	15.2	15.3
Linagliptin	26	11.2	11.2
Rivastigmine	22	9.2	9.2
Lithium	28	8.7	8.7
Lithium Bromatum	28	8.7	8.7
Telmisartan	19	8.3	8.3
Enalapril Maleate	26	8.2	8.2
Paliperidone	23	7.7	7.7
Dutasteride	8	7.7	7.7
Sodium Oxybate	60	7.2	7.2
Haloperidol	22	7.1	7.1
Haloperidol Lactate	22	7.0	7.0
Clozapine	106	6.8	6.8
Olanzapine	88	6.6	6.6
Valproic Acid	26	6.5	6.5
Valproate Sodium	17	6.4	6.4
Valsartan And Hydrochlorothiazide	11	6.3	6.3
Diphenhydramine Hcl	9	6.3	6.3
Olanzapine Pamoate	32	6.1	6.1
Sodium Chloride	60	6.0	6.0
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	23	5.9	6.0
Thyroid, Porcine	8	5.9	5.9
Remdesivir	10	5.9	5.9
Sacubitril And Valsartan	84	5.8	5.8
Meclizine	12	5.7	5.7
Meclizine Hcl 12.5Mg	10	5.7	5.7
Meclizine Hcl 25Mg	10	5.7	5.7
Meclizine Hcl 12.5 Mg	10	5.7	5.7
Meclizine Hcl 25 Mg	10	5.7	5.7
Quetiapine Fumarate	20	5.3	5.3
Irbesartan	30	5.3	5.3
Sodium Chloride Tablet	49	5.3	5.3
Sodium Chloride Tablets	49	5.3	5.3
Nevirapine	6	5.2	5.2
Piperacillin Sodium And Tazobactam Sodium	13	5.2	5.2
Metformin Hydrochloride Tablets	37	5.1	5.1
Metformin Hydrochloride Extended-Release Tablets	37	5.1	5.1
Metformin Hydrochloride Tablet	37	5.1	5.1
Metformin Hydrochloride	37	4.9	4.9
Modafinil	20	4.8	4.9
Deferasirox	16	4.7	4.7
Amphetamine	5	4.7	4.7
Carbidopa And Levodopa	28	4.6	4.6
Bupropion	26	4.6	4.6
Levodopa	7	4.5	4.5
Granisetron Hydrochloride	6	4.5	4.5
Donepezil Hydrochloride	20	4.3	4.3
Pyrazinamide	5	4.1	4.1
Armodafinil	11	4.1	4.1
Somatropin	38	4.1	4.1
Ziprasidone Mesylate	7	3.8	3.8
Sevoflurane	4	3.7	3.8
Granisetron	5	3.7	3.7
Temozolomide	10	3.7	3.7
Risperidone	59	3.5	3.5
Agalsidase Beta	4	3.4	3.4
Acalabrutinib	5	3.2	3.2
Asfotase Alfa	4	3.1	3.1
Crizotinib	5	3.1	3.1
Rifaximin	8	3.0	3.0
Ethyl Alcohol	10	2.9	2.9
Pseudoephedrine Hcl	4	2.8	2.8
Umeclidinium Bromide And Vilanterol Trifenatate	6	2.8	2.8
Nintedanib	11	2.7	2.7
Methylphenidate	10	2.7	2.7
Apalutamide	4	2.6	2.7
Mometasone Furoate And Formoterol Fumarate Dihydrate	5	2.5	2.5
Cannabidiol	7	2.3	2.3
Ravulizumab	4	2.3	2.3
Patiromer	4	2.3	2.3
Lenvatinib	9	2.1	2.1
Orlistat	6	1.8	1.8
Abaloparatide	6	1.6	1.6
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	5	1.3	1.3
Droxidopa	3	1.1	1.1
Pimavanserin Tartrate	7	1.0	1.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.