Reaction

Immunosuppressant Drug Level Decreased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,175 reports · 49 co-occurring drugs

As of the last recalculation, Immunosuppressant Drug Level Decreased appears in 1,175 FAERS reports alongside 49 co-occurring drug terms. The strongest observed disproportionality signal is TACROLIMUS (PRR 260.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Tacrolimus	780	260.4	261.7
Tacrolimus Extended-Release Capsules	522	132.5	133.0
Tacrolimus Ointment 0.1%	513	128.7	129.3
Everolimus Tablets	75	84.6	84.9
Basiliximab	46	72.1	72.3
Mycophenolate Mofetil	349	64.3	64.5
Mycophenolate Mofetil Hydrochloride	349	64.2	64.4
Pyrazinamide	30	58.0	58.2
Rifampicin	31	55.7	55.9
Valganciclovir Hydrochloride Powder,	31	46.2	46.3
Mycophenolic Acid	69	40.5	40.6
Rifampin	32	39.9	40.0
Valganciclovir	41	39.9	40.0
Valganciclovir Hydrochloride	41	39.9	40.0
Cyclosporine	181	33.9	33.9
Mycophenilic Acid	37	32.6	32.7
Oseltamivir	14	31.5	31.6
Isoniazid	27	30.2	30.2
Everolimus	78	29.0	29.1
Anti-Thymocyte Globulin (Rabbit)	13	28.9	28.9
Sirolimus	18	24.0	24.1
Prednisolone	199	23.3	23.3
Prednisolone Oral	199	23.3	23.3
Prednisolone Oral Solution	199	23.3	23.3
Voriconazole Injection	24	20.0	20.0
Micafungin Sodium	9	18.9	19.0
Voriconazole	30	17.9	17.9
Amikacin	16	16.8	16.8
Azathioprine	75	16.0	16.1
Ketoconazole Foam	12	14.5	14.5
Ketoconazole Cream, 2%	12	14.5	14.5
Meropenem	24	13.5	13.5
Calcitriol Capsules 0.25 Mcg	14	12.5	12.5
Calcitriol Capsules 0.5 Mcg	14	12.5	12.5
Ketoconazole	12	12.4	12.4
Calcitriol	14	12.4	12.4
Insulin Glargine-Yfgn	15	12.3	12.3
Itraconazole	8	12.2	12.2
Piperacillin Sodium,Tazobactam Sodium	18	12.2	12.2
Ganciclovir	7	12.2	12.2
Ganciclovir Sodium	7	11.8	11.8
Oseltamivir Phosphate	15	11.0	11.0
Ritonavir 100 Mg	8	9.5	9.5
Entecavir	6	9.1	9.1
Ledipasvir And Sofosbuvir	9	8.3	8.4
Lumacaftor And Ivacaftor	4	8.3	8.3
Tenofovir Disoproxil Fumarate Tablets	4	8.2	8.2
Sofosbuvir	6	5.4	5.4
Elexacaftor, Tezacaftor, And Ivacaftor	3	4.3	4.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.