Reaction

Microcephaly reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,252 reports · 44 co-occurring drugs

As of the last recalculation, Microcephaly appears in 1,252 FAERS reports alongside 44 co-occurring drug terms. The strongest observed disproportionality signal is MISOPROSTOL (PRR 63.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Misoprostol	36	63.3	63.5
Lopinavir And Ritonavir	26	32.5	32.6
Valproate Sodium	38	31.5	31.5
Dimenhydrinate	18	28.5	28.5
Zidovudine	18	22.7	22.7
Valproic Acid	41	22.3	22.4
Efavirenz	14	21.1	21.1
Nicotine Polacrilex Mini	18	20.2	20.2
Nicotine Polarilex	18	20.2	20.2
Atazanavir	17	19.9	19.9
Fexofenadine Hcl	10	18.1	18.1
Lamotirigine	73	17.9	17.9
Lamotrigine Extended-Release	73	17.9	17.9
Lamotrigine Chewable Dispersible	73	17.9	17.9
Raltegravir	17	17.3	17.4
Sumatriptan Succinate	24	16.1	16.1
Ritonavir	27	15.7	15.7
Phenytoin	19	15.4	15.4
Doxepin	9	14.9	14.9
Carbamazepine	54	14.0	14.0
Lamotrigine	100	13.6	13.6
Ritonavir 100 Mg	12	13.5	13.5
Nebivolol	12	12.6	12.6
Buprenorphine Hydrochloride, Naloxone Hydrochloride	18	12.6	12.6
Abacavir Sulfate	7	12.0	12.0
Phenobarbital	10	11.6	11.6
Bleomycin Sulfate	7	11.3	11.3
Methadone	28	11.1	11.1
Darunavir	10	11.1	11.1
Progesterone	15	11.0	11.0
Zonisamide	9	10.2	10.2
Lamivudine	18	9.8	9.8
Levetiracetam	74	9.7	9.7
Sumatriptan	21	9.3	9.3
Levetiracetam In Sodium Chloride	41	9.1	9.1
Levetiracetam Oral	41	9.1	9.1
Levetiracetam Injection	41	9.1	9.1
Clobazam	13	8.9	8.9
Nicotine Polacrilex	18	7.9	7.9
Fexofenadine Hydrochloride	10	7.7	7.7
Nicotine	18	7.5	7.5
Emtricitabine And Tenofovir Disoproxil Fumarate	14	5.1	5.2
Buprenorphine	19	3.5	3.5
Etonogestrel	6	2.1	2.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.