Reaction

Multiple Drug Overdose Intentional reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,220 reports · 75 co-occurring drugs

As of the last recalculation, Multiple Drug Overdose Intentional appears in 3,220 FAERS reports alongside 75 co-occurring drug terms. The strongest observed disproportionality signal is DERMA FOAM EXCEL HAND SANITIZER (PRR 97.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Derma Foam Excel Hand Sanitizer	116	97.3	98.7
Ethanol	116	96.9	98.4
Alcohol	269	48.8	49.1
Ethyl Alcohol	152	37.9	38.1
Carisoprodol	101	35.3	35.5
Diphenhydramine Hcl	59	34.9	35.0
Isopropyl Alcohol	156	31.3	31.4
Methadone Hydrochloride	49	29.7	29.8
Lithium Carbonate	48	18.5	18.6
Amphetamine	19	14.9	15.0
Diazepam Oral Solution (Concentrate)	180	13.8	13.8
Diazepam Oral	180	13.8	13.8
Oxycodone And Acetaminophen Tablets	22	12.0	12.0
Olanzapine Pamoate	72	11.6	11.6
Diazepam	205	11.6	11.6
Risperidone	220	11.4	11.4
Quetiapine Fumarate	49	10.9	10.9
Theophylline	19	10.7	10.8
Alprazolam	312	10.7	10.7
Escitalopram Oxalate	116	10.6	10.6
Theophylline Anhydrous	20	10.5	10.5
Mirtazapine	142	10.4	10.5
Valproate Sodium	33	10.4	10.4
Citalopram Hydrobromide	164	10.4	10.4
Lorazepam	258	10.0	10.0
Fluoxetine	94	9.4	9.4
Citalopram	183	9.1	9.1
Cetirizine Hcl	12	8.5	8.5
Zolpidem Tartrate	166	8.3	8.3
Quetiapine	225	8.0	8.1
Oxazepam	26	7.9	7.9
Acetaminophen Tablet Extended Release	284	7.8	7.8
Pain Reliever	284	7.8	7.8
Acetaminophen 500Mg	284	7.8	7.8
Paliperidone	27	7.5	7.5
Valproic Acid	36	7.5	7.5
Olanzapine	118	7.3	7.3
Clonazepam	167	7.1	7.1
Escitslopram	62	7.0	7.0
Diltiazem Hydrochloride Extended-Release Tablets	12	6.8	6.8
Temazepam	39	6.8	6.8
Escitalopram	141	6.7	6.8
Cyclobenzaprine Hydrochloride	9	6.5	6.5
Buspirone Hydrochloride	11	6.5	6.5
Ibuprofen Capsule	188	6.4	6.4
Ibuprofen Tablet, Film Coated	188	6.4	6.4
Ibupfrofen	188	6.4	6.4
Ibuprofen Tablets Usp, 200Mg	188	6.4	6.4
Ibuprofen Oral	188	6.4	6.4
Ibuprofen Capsules 200 Mg	188	6.4	6.4
Ibuprofen 200 Mg	188	6.4	6.4
Ibuprofen 200Mg	188	6.4	6.4
Fluoxetine Hydrochloride	120	6.3	6.3
Phenytoin	20	6.2	6.2
Oxycodone And Acetaminophen	22	6.1	6.1
Carbamazepine	58	5.7	5.7
Doxepin Hydrochloride	11	5.6	5.7
Topiramate	76	5.4	5.4
Venlafaxine Hydrochloride	104	5.2	5.2
Ziprasidone	14	5.2	5.2
Doxepin	8	5.1	5.1
Paroxetine Hydrochloride Hemihydrate	26	5.1	5.1
Lamotirigine	55	5.0	5.0
Lamotrigine Extended-Release	55	5.0	5.0
Lamotrigine Chewable Dispersible	55	5.0	5.0
Ibuprofen	200	5.0	5.0
Paroxetine	26	5.0	5.0
Pseudoephedrine Hcl	8	4.7	4.7
Metformin Hcl	37	4.4	4.4
Propranolol Hydrochloride	47	4.3	4.3
Ziprasidone Mesylate	9	4.1	4.1
Eszopiclone	16	4.1	4.1
Loperamide Hcl	8	4.0	4.0
Methadone	26	4.0	4.0
Hydrocodone Bitartrate	13	1.9	1.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.