Reaction

Speech Disorder Developmental reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,847 reports · 47 co-occurring drugs

As of the last recalculation, Speech Disorder Developmental appears in 2,847 FAERS reports alongside 47 co-occurring drug terms. The strongest observed disproportionality signal is VALPROATE SODIUM (PRR 84.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Valproate Sodium	220	84.3	85.2
Nevirapine	83	69.3	69.9
Oxymorphone Hydrochloride	94	60.9	61.4
Tramadol Hydrochloride	278	59.7	60.2
Fentanyl Citrate	138	59.3	59.7
Oxycodone Hydrochloride And Acetaminophen	382	32.5	32.6
Valproic Acid	101	24.3	24.3
Zidovudine	41	22.7	22.8
Abacavir Sulfate	23	17.4	17.4
Phytonadione	19	16.5	16.5
Labetalol	23	12.7	12.7
Morphine Sulfate	180	11.5	11.5
Ivacaftor	12	11.1	11.1
Paroxetine Hydrochloride	119	9.9	9.9
Oxycodone And Acetaminophen	31	9.8	9.8
Phenobarbital	19	9.6	9.7
Lamivudine	39	9.3	9.4
Misoprostol	12	9.0	9.1
Divalproex Sodium	54	8.6	8.6
Lamotirigine	81	8.5	8.5
Lamotrigine Extended-Release	81	8.5	8.5
Lamotrigine Chewable Dispersible	81	8.5	8.5
Oxcarbazepine	37	8.4	8.4
Lamivudine Oral	28	8.2	8.2
Tiotropium Bromide Inhalation Spray	12	7.9	7.9
Acetaminophen And Codeine	13	7.8	7.8
Lamotrigine	123	7.1	7.1
Progesterone	20	6.4	6.4
Lithium	22	6.4	6.4
Lithium Bromatum	22	6.4	6.4
Emtricitabine And Tenofovir Disoproxil Fumarate	39	6.3	6.3
Carbamazepine	54	6.0	6.0
Vigabatrin	11	5.5	5.5
Ifosfamide	16	5.5	5.5
Paroxetine Hydrochloride Hemihydrate	23	5.1	5.1
Norepinephrine	7	4.8	4.8
Thiotepa	6	4.6	4.6
Clobazam	15	4.5	4.5
Dornase Alfa	11	4.1	4.1
Levetiracetam	70	3.9	3.9
Buprenorphine Hydrochloride, Naloxone Hydrochloride	11	3.3	3.3
Levetiracetam In Sodium Chloride	35	3.3	3.3
Levetiracetam Oral	35	3.3	3.3
Levetiracetam Injection	35	3.3	3.3
Rimegepant Sulfate	5	2.9	2.9
Peginterferon Beta-1A	4	2.2	2.2
Tapentadol Hydrochloride	7	1.5	1.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.