OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Methotrexate Sodium

1,253 flagged reaction(s) · 2,451,188 total co-reports · max PRR 283.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Anti-cyclic Citrullinated Peptide Antibody Positive 6,113 283.5 287.1 signal
2 Rheumatoid Factor Positive 4,842 237.4 239.8 signal
3 Swollen Joint Count Increased 2,499 180.2 181.2 signal
4 Anti-cyclic Citrullinated Peptide Antibody 527 167.0 167.2 signal
5 Red Blood Cell Sedimentation Rate Abnormal 1,797 150.3 150.9 signal
6 Pemphigus 9,382 135.9 138.6 signal
7 Synovitis 13,569 133.8 137.6 signal
8 Rheumatic Fever 3,282 133.3 134.2 signal
9 Lupus Vulgaris 867 117.7 118.0 signal
10 C-reactive Protein Abnormal 4,659 117.0 118.2 signal
11 Deep Vein Thrombosis Postoperative 1,372 101.8 102.0 signal
12 Duodenal Ulcer Perforation 5,067 97.3 98.3 signal
13 C-reactive Protein 617 92.5 92.6 signal
14 Hand Deformity 8,885 92.3 94.0 signal
15 Granuloma Skin 539 80.8 80.9 signal
16 Epstein Barr Virus Positive Mucocutaneous Ulcer 324 80.7 80.7 signal
17 Rheumatoid Nodule 1,759 74.3 74.6 signal
18 Facet Joint Syndrome 1,964 71.6 71.9 signal
19 Bone Erosion 2,084 61.7 62.0 signal
20 X-ray Abnormal 1,043 60.7 60.8 signal
21 Adjustment Disorder With Depressed Mood 1,109 52.7 52.8 signal
22 Dislocation Of Vertebra 1,211 51.4 51.6 signal
23 Body Height Below Normal 343 48.0 48.0 signal
24 Muscle Injury 4,306 47.5 47.9 signal
25 Helicobacter Infection 5,277 46.1 46.6 signal
26 Lymphoproliferative Disorder 1,503 44.9 45.1 signal
27 Sleep Disorder Due To General Medical Condition, Insomnia Type 3,191 42.2 42.5 signal
28 Enthesopathy 781 42.1 42.2 signal
29 Seronegative Arthritis 555 42.0 42.0 signal
30 Folliculitis 5,035 40.8 41.2 signal
31 Dactylitis 468 39.1 39.1 signal
32 Retinitis 790 38.5 38.6 signal
33 Contraindicated Product Administered 14,237 38.3 39.5 signal
34 Rheumatoid Lung 451 37.7 37.8 signal
35 Drug Clearance Decreased 570 35.4 35.5 signal
36 Joint Destruction 684 33.3 33.3 signal
37 Pericarditis 6,863 30.0 30.4 signal
38 Peripheral Venous Disease 1,635 29.6 29.7 signal
39 Blood Parathyroid Hormone Decreased 609 29.5 29.6 signal
40 Blood Pressure Diastolic Abnormal 1,029 28.5 28.6 signal
41 Blood Pressure Systolic Abnormal 987 28.1 28.1 signal
42 Tenosynovitis 1,088 27.7 27.8 signal
43 Juvenile Idiopathic Arthritis 963 27.7 27.7 signal
44 Glossodynia 8,747 27.5 28.0 signal
45 Red Blood Cell Sedimentation Rate Increased 4,280 26.9 27.1 signal
46 Rheumatoid Arthritis 42,466 25.7 28.1 signal
47 Drug Tolerance Decreased 1,041 25.3 25.3 signal
48 Blood Iron Abnormal 356 24.3 24.3 signal
49 Epstein-barr Virus Associated Lymphoproliferative Disorder 619 22.9 22.9 signal
50 Grip Strength Decreased 3,002 22.3 22.4 signal
51 Acute Graft Versus Host Disease 1,571 22.0 22.1 signal
52 Chronic Graft Versus Host Disease 1,227 21.7 21.8 signal
53 Panniculitis 805 21.4 21.4 signal
54 Hypofibrinogenaemia 323 21.3 21.3 signal
55 Arthrodesis 335 20.9 21.0 signal
56 Joint Range Of Motion Decreased 4,346 20.6 20.7 signal
57 Systemic Lupus Erythematosus 11,381 20.2 20.7 signal
58 Finger Deformity 1,547 20.0 20.0 signal
59 Acute Graft Versus Host Disease In Skin 866 19.5 19.5 signal
60 Acute Graft Versus Host Disease In Intestine 420 18.2 18.2 signal
61 Wound 8,227 17.9 18.2 signal
62 Psoriatic Arthropathy 10,957 16.0 16.3 signal
63 Leukoencephalopathy 1,008 15.7 15.7 signal
64 Histoplasmosis Disseminated 417 15.6 15.6 signal
65 Epstein-barr Virus Infection Reactivation 335 15.3 15.3 signal
66 Secondary Immunodeficiency 314 15.2 15.2 signal
67 Arthropathy 14,577 15.1 15.5 signal
68 Central Nervous System Lymphoma 358 15.0 15.0 signal
69 Myelopathy 484 14.5 14.5 signal
70 Drug Intolerance 24,385 14.4 15.2 signal
71 Bursitis 3,052 14.4 14.5 signal
72 Polyarthritis 1,326 14.4 14.4 signal
73 Graft Versus Host Disease In Gastrointestinal Tract 533 14.2 14.2 signal
74 Foot Deformity 2,775 14.2 14.3 signal
75 Breast Cancer Stage Iii 1,606 14.2 14.2 signal
76 Irritable Bowel Syndrome 5,198 13.7 13.8 signal
77 Onychomadesis 1,010 13.7 13.7 signal
78 Therapeutic Product Effect Decreased 10,761 13.6 13.9 signal
79 Fibromyalgia 5,659 12.9 13.1 signal
80 Onychomycosis 1,020 12.9 12.9 signal
81 Wound Infection 2,504 12.7 12.8 signal
82 Drug Specific Antibody 314 12.7 12.7 signal
83 Febrile Bone Marrow Aplasia 944 12.4 12.4 signal
84 Hypercholesterolaemia 2,132 12.2 12.2 signal
85 Sacroiliitis 421 12.1 12.1 signal
86 Graft Versus Host Disease In Skin 488 12.1 12.1 signal
87 C-reactive Protein Increased 8,059 12.1 12.3 signal
88 Joint Arthroplasty 395 12.0 12.0 signal
89 Lip Dry 1,963 11.9 12.0 signal
90 Pseudomonal Sepsis 380 11.7 11.7 signal
91 Joint Effusion 1,491 11.7 11.7 signal
92 Tuberculin Test Positive 549 11.6 11.6 signal
93 Scleritis 340 11.5 11.5 signal
94 Treatment Failure 17,162 11.2 11.6 signal
95 Pulmonary Fibrosis 3,946 11.1 11.1 signal
96 Joint Swelling 24,834 11.0 11.6 signal
97 Cytomegalovirus Chorioretinitis 396 11.0 11.0 signal
98 Synovial Cyst 949 10.9 10.9 signal
99 Impaired Healing 6,707 10.9 11.1 signal
100 Pustular Psoriasis 689 10.6 10.6 signal
101 Acute Lymphocytic Leukaemia Recurrent 515 10.6 10.6 signal
102 Liver Function Test Increased 4,192 10.4 10.5 signal
103 Osteoarthritis 8,341 10.4 10.6 signal
104 Venoocclusive Liver Disease 962 10.3 10.4 signal
105 Limb Deformity 310 10.3 10.3 signal
106 Antibody Test Positive 322 10.1 10.1 signal
107 Human Herpesvirus 6 Infection 365 10.1 10.1 signal
108 Arthritis Bacterial 780 10.0 10.1 signal
109 Graft Versus Host Disease 1,365 9.9 9.9 signal
110 Lower Respiratory Tract Infection 8,273 9.5 9.6 signal
111 Liver Injury 4,372 9.4 9.5 signal
112 Hepatic Enzyme Increased 12,178 9.3 9.5 signal
113 Mucosal Inflammation 4,640 9.2 9.3 signal
114 Diffuse Large B-cell Lymphoma 1,358 9.2 9.2 signal
115 Exostosis 1,582 8.9 8.9 signal
116 Epstein-barr Virus Infection 1,069 8.8 8.8 signal
117 Autoimmune Disorder 1,635 8.8 8.8 signal
118 Alanine Aminotransferase Abnormal 355 8.7 8.7 signal
119 Disseminated Tuberculosis 430 8.6 8.6 signal
120 Musculoskeletal Stiffness 14,739 8.6 8.8 signal
121 Latent Tuberculosis 351 8.6 8.6 signal
122 Venoocclusive Disease 419 8.5 8.5 signal
123 Infusion Related Reaction 11,018 8.5 8.7 signal
124 Nail Disorder 1,449 8.5 8.5 signal
125 Live Birth 1,384 8.5 8.5 signal
126 Knee Arthroplasty 3,453 8.4 8.5 signal
127 Hip Arthroplasty 2,485 8.3 8.4 signal
128 Sciatica 2,592 8.3 8.3 signal
129 Cytomegalovirus Infection Reactivation 697 8.3 8.3 signal
130 Blood Pressure Diastolic Decreased 1,204 8.2 8.3 signal
131 Hepatic Fibrosis 550 8.1 8.2 signal
132 Adenovirus Infection 457 8.1 8.1 signal
133 Cystitis Haemorrhagic 639 8.0 8.0 signal
134 Faecal Calprotectin Increased 495 8.0 8.0 signal
135 Blepharospasm 985 8.0 8.0 signal
136 Joint Stiffness 4,159 8.0 8.1 signal
137 Mouth Ulceration 3,323 8.0 8.0 signal
138 Shoulder Arthroplasty 418 7.9 8.0 signal
139 Nodule 2,049 7.9 7.9 signal
140 Spinal Stenosis 637 7.9 7.9 signal
141 Pneumocystis Jiroveci Pneumonia 351 7.8 7.8 signal
142 Lupus-like Syndrome 1,389 7.7 7.8 signal
143 Inflammation 7,854 7.7 7.8 signal
144 Pneumocystis Jirovecii Pneumonia 1,525 7.6 7.7 signal
145 B-cell Lymphoma 520 7.6 7.6 signal
146 Stomatitis 9,187 7.6 7.7 signal
147 Obesity 2,406 7.5 7.6 signal
148 Blood Pressure Diastolic Increased 691 7.4 7.5 signal
149 Pulmonary Tuberculosis 632 7.4 7.4 signal
150 Aspergillus Infection 954 7.3 7.3 signal
151 Fine Motor Skill Dysfunction 423 7.3 7.3 signal
152 Inflammatory Marker Increased 715 7.3 7.3 signal
153 Swelling 13,593 7.2 7.4 signal
154 Histiocytosis Haematophagic 438 7.2 7.2 signal
155 Mycobacterium Tuberculosis Complex Test Positive 343 7.2 7.2 signal
156 Skin Necrosis 753 7.2 7.2 signal
157 Cushingoid 466 7.2 7.2 signal
158 Ankylosing Spondylitis 1,873 7.1 7.2 signal
159 Uveitis 1,938 7.1 7.1 signal
160 Cytomegalovirus Viraemia 619 7.0 7.0 signal
161 Joint Dislocation 1,486 7.0 7.0 signal
162 Demyelination 578 6.9 6.9 signal
163 Basal Cell Carcinoma 2,181 6.9 6.9 signal
164 Sensitivity To Weather Change 729 6.9 6.9 signal
165 Sarcoidosis 659 6.8 6.8 signal
166 Chondropathy 378 6.8 6.8 signal
167 Infusion Site Reaction 402 6.8 6.8 signal
168 Arthritis Infective 632 6.7 6.7 signal
169 Type 2 Diabetes Mellitus 4,533 6.6 6.6 signal
170 Bk Virus Infection 449 6.6 6.6 signal
171 Dermatomyositis 333 6.4 6.4 signal
172 Blood Pressure Systolic Increased 2,538 6.3 6.3 signal
173 Pneumonia Viral 411 6.3 6.3 signal
174 Immunosuppression 1,113 6.2 6.3 signal
175 Pulmonary Toxicity 900 6.2 6.3 signal
176 Spondylitis 465 6.2 6.2 signal
177 Walking Aid User 845 6.2 6.2 signal
178 Arthritis 10,004 6.2 6.3 signal
179 Loss Of Personal Independence In Daily Activities 6,037 6.2 6.2 signal
180 Antinuclear Antibody Positive 414 6.2 6.2 signal
181 Posterior Reversible Encephalopathy Syndrome 1,188 6.1 6.1 signal
182 Tuberculosis 1,604 6.1 6.1 signal
183 Pancytopenia 6,933 6.0 6.1 signal
184 Mobility Decreased 8,825 6.0 6.1 signal
185 Laryngitis 1,321 5.9 5.9 signal
186 Discomfort 7,364 5.9 5.9 signal
187 Bronchiectasis 809 5.9 5.9 signal
188 Musculoskeletal Pain 6,349 5.8 5.9 signal
189 Febrile Neutropenia 7,894 5.7 5.8 signal
190 Foot Operation 577 5.6 5.6 signal
191 Hepatic Enzyme Abnormal 584 5.6 5.6 signal
192 Maternal Exposure Timing Unspecified 434 5.6 5.6 signal
193 Acute Lymphocytic Leukaemia 327 5.5 5.5 signal
194 Body Temperature Decreased 1,141 5.5 5.5 signal
195 Blister 6,436 5.5 5.6 signal
196 Immunodeficiency 1,692 5.5 5.5 signal
197 Staphylococcal Sepsis 564 5.4 5.5 signal
198 Blood Pressure Fluctuation 2,735 5.4 5.5 signal
199 Granuloma 393 5.4 5.4 signal
200 Hepatic Cirrhosis 2,117 5.4 5.4 signal
201 Aphthous Ulcer 868 5.4 5.4 signal
202 Tenderness 1,181 5.4 5.4 signal
203 Gait Inability 3,726 5.4 5.4 signal
204 Pulmonary Mass 1,664 5.3 5.4 signal
205 Back Injury 1,210 5.3 5.4 signal
206 Lung Adenocarcinoma 336 5.3 5.3 signal
207 Sinusitis 11,428 5.3 5.4 signal
208 Injection Site Haematoma 1,629 5.3 5.3 signal
209 Blood Cholesterol Increased 5,182 5.3 5.4 signal
210 Blood Culture Positive 336 5.3 5.3 signal
211 Therapeutic Product Effect Incomplete 7,813 5.3 5.3 signal
212 Hepatotoxicity 2,437 5.2 5.3 signal
213 Joint Lock 312 5.2 5.2 signal
214 Bronchopulmonary Aspergillosis 843 5.2 5.2 signal
215 Haemophagocytic Lymphohistiocytosis 785 5.2 5.2 signal
216 Crepitations 324 5.1 5.1 signal
217 Iritis 327 5.1 5.1 signal
218 Hepatic Steatosis 1,986 5.1 5.1 signal
219 Injection Site Irritation 1,339 5.0 5.0 signal
220 Hepatitis B Reactivation 336 5.0 5.0 signal
221 Lower Limb Fracture 2,014 5.0 5.0 signal
222 Skin Ulcer 2,713 5.0 5.0 signal
223 Infection 15,140 5.0 5.1 signal
224 Apparent Death 383 5.0 5.0 signal
225 Anal Fissure 554 4.9 4.9 signal
226 Night Sweats 3,289 4.8 4.9 signal
227 Pharyngitis 1,267 4.8 4.8 signal
228 Haematotoxicity 942 4.8 4.8 signal
229 Gastrointestinal Disorder 8,944 4.8 4.9 signal
230 Drug Hypersensitivity 19,622 4.8 4.9 signal
231 Pyoderma Gangrenosum 360 4.8 4.8 signal
232 Drug Effect Incomplete 3,716 4.8 4.8 signal
233 Drug Tolerance 509 4.7 4.7 signal
234 Pleurisy 597 4.7 4.7 signal
235 Herpes Simplex 647 4.7 4.7 signal
236 Bacterial Sepsis 324 4.7 4.7 signal
237 Skin Plaque 830 4.6 4.6 signal
238 Arthralgia 40,408 4.6 4.9 signal
239 Peripheral Swelling 14,913 4.6 4.7 signal
240 Lung Disorder 4,738 4.5 4.6 signal
241 Abdominal Discomfort 16,137 4.5 4.7 signal
242 Immobile 418 4.5 4.5 signal
243 Ear Pain 1,868 4.5 4.5 signal
244 Gastrointestinal Toxicity 450 4.5 4.5 signal
245 Cytopenia 1,135 4.5 4.5 signal
246 Bone Marrow Failure 1,939 4.4 4.5 signal
247 Product Label Confusion 551 4.4 4.4 signal
248 Liver Disorder 4,186 4.4 4.5 signal
249 Cytomegalovirus Infection 1,570 4.4 4.4 signal
250 Staphylococcal Bacteraemia 409 4.4 4.4 signal
251 Neurotoxicity 1,637 4.4 4.4 signal
252 Coeliac Disease 918 4.4 4.4 signal
253 Tonsillitis 484 4.3 4.3 signal
254 Fear Of Injection 647 4.3 4.3 signal
255 Intentional Product Use Issue 8,131 4.3 4.4 signal
256 Pneumonia Fungal 358 4.3 4.3 signal
257 Therapy Non-responder 4,096 4.3 4.3 signal
258 Anal Abscess 492 4.3 4.3 signal
259 Anal Fistula 487 4.3 4.3 signal
260 Diverticulitis 2,518 4.3 4.3 signal
261 Wheelchair User 405 4.2 4.2 signal
262 Erythema Nodosum 316 4.2 4.2 signal
263 Viral Upper Respiratory Tract Infection 431 4.2 4.2 signal
264 Spinal Osteoarthritis 795 4.2 4.2 signal
265 Lymphoma 1,386 4.2 4.2 signal
266 Ulcer 1,422 4.2 4.2 signal
267 Thrombotic Microangiopathy 864 4.2 4.2 signal
268 Drug Specific Antibody Present 578 4.2 4.2 signal
269 Chronic Sinusitis 333 4.1 4.1 signal
270 Rhinovirus Infection 336 4.1 4.1 signal
271 Ulcer Haemorrhage 598 4.1 4.1 signal
272 Deformity 828 4.1 4.1 signal
273 Postoperative Wound Infection 595 4.1 4.1 signal
274 Abscess Limb 376 4.1 4.1 signal
275 Prescribed Overdose 1,704 4.1 4.1 signal
276 Rash Vesicular 424 4.1 4.1 signal
277 Psoriasis 11,481 4.1 4.2 signal
278 Alopecia 17,251 4.1 4.2 signal
279 Hepatitis 2,243 4.1 4.1 signal
280 Hypertriglyceridaemia 511 4.1 4.1 signal
281 Ill-defined Disorder 5,285 4.0 4.1 signal
282 Post Transplant Lymphoproliferative Disorder 436 4.0 4.0 signal
283 Oesophageal Candidiasis 343 4.0 4.0 signal
284 Osteoporosis 3,571 4.0 4.1 signal
285 Oral Herpes 1,684 4.0 4.0 signal
286 Hypertransaminasaemia 590 4.0 4.0 signal
287 Herpes Zoster 4,973 4.0 4.0 signal
288 Intervertebral Disc Degeneration 798 4.0 4.0 signal
289 Skin Papilloma 343 4.0 4.0 signal
290 Spinal Fusion Surgery 343 4.0 4.0 signal
291 Ear Infection 2,265 4.0 4.0 signal
292 Neutropenic Sepsis 608 3.9 3.9 signal
293 Tooth Abscess 868 3.9 3.9 signal
294 Escherichia Urinary Tract Infection 360 3.9 3.9 signal
295 Red Cell Distribution Width Increased 349 3.9 3.9 signal
296 Sinus Congestion 1,134 3.9 3.9 signal
297 Nasopharyngitis 15,473 3.9 4.0 signal
298 Musculoskeletal Disorder 1,590 3.8 3.9 signal
299 Tibia Fracture 391 3.8 3.8 signal
300 Tooth Infection 1,093 3.8 3.8 signal
301 Meniscus Injury 510 3.8 3.8 signal
302 Carpal Tunnel Syndrome 1,153 3.8 3.8 signal
303 Hypogammaglobulinaemia 526 3.8 3.8 signal
304 Spinal Pain 956 3.8 3.8 signal
305 Joint Injury 1,745 3.8 3.8 signal
306 Localised Infection 1,968 3.8 3.8 signal
307 Hypercalcaemia 993 3.7 3.7 signal
308 Poor Venous Access 831 3.7 3.7 signal
309 Post Procedural Infection 651 3.7 3.7 signal
310 Encephalitis 553 3.7 3.7 signal
311 Maternal Exposure During Pregnancy 7,061 3.7 3.7 signal
312 Septic Shock 3,446 3.7 3.7 signal
313 Interstitial Lung Disease 3,848 3.7 3.7 signal
314 Squamous Cell Carcinoma 744 3.6 3.6 signal
315 Drug Eruption 1,388 3.6 3.6 signal
316 Condition Aggravated 23,715 3.6 3.8 signal
317 Lung Neoplasm 336 3.6 3.6 signal
318 Organising Pneumonia 382 3.6 3.6 signal
319 Vasculitis 902 3.6 3.6 signal
320 Adrenal Insufficiency 924 3.5 3.6 signal
321 Hyperbilirubinaemia 793 3.5 3.5 signal
322 Skin Lesion 2,094 3.5 3.5 signal
323 Neck Pain 4,301 3.5 3.6 signal
324 Enterococcal Infection 372 3.5 3.5 signal
325 Adverse Reaction 1,019 3.5 3.5 signal
326 Drug Level Below Therapeutic 421 3.5 3.5 signal
327 Myelodysplastic Syndrome 1,105 3.5 3.5 signal
328 Respiratory Tract Congestion 1,213 3.5 3.5 signal
329 Bacterial Infection 1,413 3.5 3.5 signal
330 Subcutaneous Abscess 365 3.5 3.5 signal
331 Rotator Cuff Syndrome 979 3.5 3.5 signal
332 Cyst 943 3.5 3.5 signal
333 Rhinitis 610 3.5 3.5 signal
334 Muscle Spasticity 937 3.5 3.5 signal
335 Upper Respiratory Tract Infection 3,478 3.5 3.5 signal
336 Disability 1,488 3.5 3.5 signal
337 Klebsiella Infection 377 3.4 3.4 signal
338 Abscess 1,186 3.4 3.4 signal
339 Iron Deficiency 330 3.4 3.4 signal
340 Progressive Multifocal Leukoencephalopathy 609 3.4 3.4 signal
341 Clostridium Difficile Colitis 783 3.4 3.4 signal
342 Skin Infection 822 3.4 3.4 signal
343 Body Temperature Increased 1,507 3.4 3.4 signal
344 Bronchitis 5,380 3.3 3.3 signal
345 Oral Disorder 531 3.3 3.3 signal
346 Malignant Melanoma 968 3.3 3.3 signal
347 Injection Site Warmth 1,485 3.3 3.3 signal
348 Prescribed Underdose 1,435 3.3 3.3 signal
349 Liver Function Test Abnormal 2,099 3.3 3.3 signal
350 Herpes Virus Infection 413 3.3 3.3 signal
351 Nephropathy Toxic 796 3.3 3.3 signal
352 General Physical Health Deterioration 8,190 3.3 3.3 signal
353 Pseudomonas Infection 601 3.2 3.2 signal
354 Aplastic Anaemia 372 3.2 3.2 signal
355 Streptococcal Infection 395 3.2 3.2 signal
356 Sleep Disorder 4,958 3.2 3.3 signal
357 Enteritis 449 3.2 3.2 signal
358 Myositis 634 3.2 3.2 signal
359 Leukopenia 3,521 3.2 3.2 signal
360 Hypersensitivity 13,072 3.2 3.3 signal
361 Breast Cancer Stage Ii 592 3.2 3.2 signal
362 Drug-induced Liver Injury 2,174 3.2 3.2 signal
363 Drug Ineffective 92,614 3.2 3.7 signal
364 Stress Fracture 380 3.2 3.2 signal
365 Transaminases Increased 1,546 3.2 3.2 signal
366 Hypoalbuminaemia 531 3.2 3.2 signal
367 Candida Infection 1,149 3.1 3.1 signal
368 Vaginal Infection 324 3.1 3.1 signal
369 Spinal Column Stenosis 329 3.1 3.1 signal
370 Heart Rate Decreased 2,423 3.1 3.1 signal
371 Intervertebral Disc Protrusion 1,505 3.1 3.1 signal
372 Acute Myeloid Leukaemia 1,068 3.1 3.1 signal
373 Erysipelas 346 3.1 3.1 signal
374 Pharyngolaryngeal Pain 368 3.1 3.1 signal
375 Tendon Disorder 446 3.1 3.1 signal
376 Colitis Microscopic 320 3.1 3.1 signal
377 Bacteraemia 801 3.1 3.1 signal
378 Osteomyelitis 1,229 3.1 3.1 signal
379 Contusion 6,489 3.1 3.1 signal
380 Pain In Extremity 19,877 3.1 3.2 signal
381 Spinal Disorder 632 3.0 3.0 signal
382 Respiratory Tract Infection 1,723 3.0 3.0 signal
383 Therapy Partial Responder 998 3.0 3.0 signal
384 Hyperkeratosis 364 3.0 3.0 signal
385 Therapeutic Response Decreased 3,958 3.0 3.0 signal
386 Respiratory Disorder 1,967 3.0 3.0 signal
387 Cellulitis 3,298 3.0 3.0 signal
388 Staphylococcal Infection 2,160 3.0 3.0 signal
389 Immune System Disorder 857 3.0 3.0 signal
390 Injection Site Reaction 4,462 3.0 3.0 signal
391 Osteopenia 992 3.0 3.0 signal
392 Dyslipidaemia 330 2.9 2.9 signal
393 Wheezing 3,838 2.9 3.0 signal
394 Pneumonitis 1,754 2.9 3.0 signal
395 Cystitis 2,071 2.9 2.9 signal
396 Incorrect Route Of Product Administration 1,085 2.9 2.9 signal
397 Oral Candidiasis 839 2.9 2.9 signal
398 Acute Respiratory Distress Syndrome 1,137 2.9 2.9 signal
399 Lung Infiltration 571 2.9 2.9 signal
400 Pyelonephritis 551 2.9 2.9 signal
401 Gastrointestinal Infection 571 2.9 2.9 signal
402 Foot Fracture 1,215 2.9 2.9 signal
403 Pain 39,309 2.9 3.1 signal
404 Tendonitis 993 2.9 2.9 signal
405 Local Swelling 1,115 2.9 2.9 signal
406 Sepsis 6,978 2.8 2.9 signal
407 Oedema 3,368 2.8 2.8 signal
408 Gastrointestinal Inflammation 484 2.8 2.8 signal
409 Escherichia Infection 508 2.8 2.8 signal
410 Fistula 698 2.8 2.8 signal
411 Dermatitis Allergic 771 2.8 2.8 signal
412 Arthropod Bite 453 2.8 2.8 signal
413 Skin Laceration 658 2.8 2.8 signal
414 Pharyngitis Streptococcal 656 2.7 2.7 signal
415 Squamous Cell Carcinoma Of Skin 364 2.7 2.7 signal
416 Drug Effect Decreased 3,299 2.7 2.7 signal
417 Meningitis 403 2.7 2.7 signal
418 Tongue Disorder 439 2.7 2.7 signal
419 Road Traffic Accident 2,519 2.7 2.7 signal
420 Musculoskeletal Discomfort 1,033 2.7 2.7 signal
421 Cataract 3,561 2.7 2.7 signal
422 Tendon Rupture 741 2.7 2.7 signal
423 Alanine Aminotransferase Increased 3,675 2.7 2.7 signal
424 Impaired Work Ability 1,279 2.7 2.7 signal
425 Gastroenteritis 869 2.7 2.7 signal
426 Pneumonia Bacterial 544 2.7 2.7 signal
427 Viral Infection 1,960 2.7 2.7 signal
428 Congenital Anomaly 459 2.7 2.7 signal
429 Diverticulum 421 2.6 2.6 signal
430 Injection Site Pruritus 3,887 2.6 2.6 signal
431 Drug Ineffective For Unapproved Indication 3,248 2.6 2.6 signal
432 Skin Mass 386 2.6 2.6 signal
433 Multiple Organ Dysfunction Syndrome 1,620 2.6 2.6 signal
434 Kidney Infection 1,138 2.6 2.6 signal
435 Pelvic Fracture 450 2.6 2.6 signal
436 Odynophagia 340 2.6 2.6 signal
437 Lung Infection 906 2.6 2.6 signal
438 Sensory Loss 464 2.6 2.6 signal
439 Nerve Compression 528 2.6 2.6 signal
440 Fungal Infection 1,908 2.6 2.6 signal
441 Furuncle 453 2.6 2.6 signal
442 Sputum Discoloured 540 2.6 2.6 signal
443 Covid-19 Pneumonia 678 2.6 2.6 signal
444 Decreased Immune Responsiveness 557 2.6 2.6 signal
445 Frequent Bowel Movements 1,530 2.6 2.6 signal
446 Tooth Fracture 626 2.6 2.6 signal
447 Second Primary Malignancy 471 2.5 2.5 signal
448 Myelosuppression 1,927 2.5 2.6 signal
449 Atelectasis 549 2.5 2.5 signal
450 Lymphadenopathy 2,001 2.5 2.5 signal
451 Hypertension 11,944 2.5 2.6 signal
452 Bone Disorder 1,033 2.5 2.5 signal
453 Pneumonia 18,161 2.5 2.6 signal
454 Hemiparesis 957 2.5 2.5 signal
455 Product Use Issue 10,473 2.5 2.6 signal
456 Lymphopenia 786 2.5 2.5 signal
457 Renal Cyst 443 2.5 2.5 signal
458 Tumour Lysis Syndrome 486 2.5 2.5 signal
459 Emphysema 561 2.5 2.5 signal
460 Mass 776 2.5 2.5 signal
461 Vitamin D Decreased 472 2.5 2.5 signal
462 Oropharyngeal Pain 5,084 2.5 2.5 signal
463 Skin Atrophy 315 2.5 2.5 signal
464 Injury 3,865 2.5 2.5 signal
465 Pyrexia 18,860 2.4 2.5 signal
466 Urosepsis 502 2.4 2.4 signal
467 Diarrhoea Haemorrhagic 509 2.4 2.4 signal
468 Spinal Compression Fracture 456 2.4 2.4 signal
469 Hepatomegaly 536 2.4 2.4 signal
470 Breast Mass 362 2.4 2.4 signal
471 Secretion Discharge 664 2.4 2.4 signal
472 Weight Increased 11,971 2.4 2.4 signal
473 Oral Pain 1,195 2.4 2.4 signal
474 Glaucoma 1,010 2.3 2.3 signal
475 Gastrointestinal Pain 572 2.3 2.3 signal
476 Pulmonary Haemorrhage 408 2.3 2.3 signal
477 Rash Pustular 378 2.3 2.3 signal
478 Rash 22,362 2.3 2.4 signal
479 Maternal Exposure Before Pregnancy 350 2.3 2.3 signal
480 Injection Site Erythema 6,357 2.3 2.3 signal
481 Ligament Sprain 508 2.3 2.3 signal
482 Influenza 5,754 2.3 2.3 signal
483 Hepatitis B 312 2.3 2.3 signal
484 Photosensitivity Reaction 841 2.3 2.3 signal
485 Facial Paralysis 433 2.3 2.3 signal
486 Papule 354 2.3 2.3 signal
487 Gingival Pain 405 2.3 2.3 signal
488 Drug Level Decreased 520 2.3 2.3 signal
489 Hypoaesthesia 7,606 2.3 2.3 signal
490 Device Related Infection 783 2.3 2.3 signal
491 Motor Dysfunction 513 2.3 2.3 signal
492 Disseminated Intravascular Coagulation 714 2.3 2.3 signal
493 Dysstasia 1,481 2.3 2.3 signal
494 Productive Cough 2,374 2.2 2.2 signal
495 Rhinorrhoea 3,232 2.2 2.2 signal
496 Gait Disturbance 9,606 2.2 2.3 signal
497 Encephalopathy 1,221 2.2 2.2 signal
498 Arterial Occlusive Disease 393 2.2 2.2 signal
499 Respiratory Rate Increased 442 2.2 2.2 signal
500 Eye Infection 554 2.2 2.2 signal
501 Colitis 1,860 2.2 2.2 signal
502 Hiatus Hernia 638 2.2 2.2 signal
503 Limb Injury 1,329 2.2 2.2 signal
504 Limb Discomfort 1,518 2.2 2.2 signal
505 Tooth Disorder 1,096 2.2 2.2 signal
506 Hepatocellular Injury 697 2.2 2.2 signal
507 Drug Level Increased 812 2.2 2.2 signal
508 Iron Deficiency Anaemia 450 2.2 2.2 signal
509 Nephrolithiasis 2,239 2.2 2.2 signal
510 Ankle Fracture 758 2.2 2.2 signal
511 Hemiplegia 408 2.2 2.2 signal
512 Taste Disorder 978 2.2 2.2 signal
513 Blood Test Abnormal 684 2.2 2.2 signal
514 Increased Tendency To Bruise 449 2.2 2.2 signal
515 Thrombocytopenia 5,429 2.2 2.2 signal
516 Polyneuropathy 579 2.2 2.2 signal
517 Back Disorder 793 2.2 2.2 signal
518 Aspartate Aminotransferase Increased 2,572 2.2 2.2 signal
519 Clostridium Difficile Infection 1,046 2.2 2.2 signal
520 Delirium 1,665 2.1 2.1 signal
521 Epilepsy 1,465 2.1 2.1 signal
522 Blood Iron Decreased 565 2.1 2.1 signal
523 Weight Fluctuation 498 2.1 2.1 signal
524 Injection Site Swelling 3,617 2.1 2.1 signal
525 Hepatic Cytolysis 581 2.1 2.1 signal
526 Injection Site Induration 616 2.1 2.1 signal
527 Hand Fracture 336 2.1 2.1 signal
528 Cardiotoxicity 420 2.1 2.1 signal
529 Polyp 310 2.1 2.1 signal
530 Mouth Haemorrhage 346 2.1 2.1 signal
531 Injection Site Pain 14,293 2.1 2.1 signal
532 Blood Albumin Decreased 370 2.1 2.1 signal
533 Groin Pain 412 2.1 2.1 signal
534 Knee Operation 452 2.1 2.1 signal
535 Skin Haemorrhage 671 2.1 2.1 signal
536 Gastric Ulcer 885 2.1 2.1 signal
537 Oxygen Saturation Decreased 2,594 2.1 2.1 signal
538 Neutropenia 6,288 2.1 2.1 signal
539 Injection Site Bruising 3,641 2.1 2.1 signal
540 Gastroenteritis Viral 836 2.1 2.1 signal
541 Off Label Use 39,859 2.0 2.1 signal
542 Urticaria 7,622 2.0 2.1 signal
543 Pulmonary Thrombosis 495 2.0 2.0 signal
544 Multi-organ Failure 795 2.0 2.0 signal
545 Gastric Disorder 1,571 2.0 2.0 signal
546 Uterine Leiomyoma 331 2.0 2.0 signal
547 Dry Mouth 3,644 2.0 2.0 no signal
548 Dyspepsia 4,406 2.0 2.0 no signal
549 Skin Cancer 965 2.0 2.0 no signal
550 Skin Reaction 630 2.0 2.0 no signal
551 Muscular Weakness 5,048 2.0 2.0 no signal
552 Migraine 4,208 2.0 2.0 no signal
553 Ovarian Cyst 445 2.0 2.0 no signal
554 Vitamin D Deficiency 430 2.0 2.0 no signal
555 Product Use In Unapproved Indication 10,741 2.0 2.0 no signal
556 Cardiac Murmur 382 1.9 1.9 no signal
557 Skin Disorder 1,461 1.9 2.0 no signal
558 Nerve Injury 489 1.9 1.9 no signal
559 Colitis Ulcerative 1,950 1.9 1.9 no signal
560 Platelet Count Increased 571 1.9 1.9 no signal
561 Coagulopathy 726 1.9 1.9 no signal
562 Eye Inflammation 411 1.9 1.9 no signal
563 Back Pain 10,068 1.9 1.9 no signal
564 Therapeutic Response Shortened 1,376 1.9 1.9 no signal
565 Musculoskeletal Chest Pain 668 1.9 1.9 no signal
566 Confusional State 6,975 1.9 1.9 no signal
567 Pneumothorax 682 1.9 1.9 no signal
568 Blood Lactate Dehydrogenase Increased 686 1.9 1.9 no signal
569 Pleural Effusion 2,616 1.9 1.9 no signal
570 Respiratory Failure 3,132 1.9 1.9 no signal
571 Dental Caries 471 1.9 1.9 no signal
572 Injection Site Rash 1,292 1.9 1.9 no signal
573 Toothache 769 1.9 1.9 no signal
574 Hepatic Function Abnormal 1,574 1.9 1.9 no signal
575 Scab 481 1.9 1.9 no signal
576 Disease Recurrence 2,023 1.9 1.9 no signal
577 Urinary Tract Infection 7,207 1.9 1.9 no signal
578 Nasal Congestion 2,476 1.9 1.9 no signal
579 Hernia 814 1.9 1.9 no signal
580 Fatigue 32,750 1.9 1.9 no signal
581 Exposure During Pregnancy 2,621 1.9 1.9 no signal
582 Cough 11,779 1.9 1.9 no signal
583 Oedema Peripheral 5,143 1.9 1.9 no signal
584 Pregnancy 850 1.9 1.9 no signal
585 Appendicitis 390 1.9 1.9 no signal
586 Injection Site Discolouration 520 1.9 1.9 no signal
587 Gastritis 1,101 1.9 1.9 no signal
588 Splenomegaly 489 1.8 1.8 no signal
589 Haematochezia 2,299 1.8 1.9 no signal
590 Sinus Disorder 825 1.8 1.8 no signal
591 Femur Fracture 1,291 1.8 1.8 no signal
592 Rash Pruritic 2,236 1.8 1.8 no signal
593 Stress 2,981 1.8 1.8 no signal
594 Aortic Aneurysm 317 1.8 1.8 no signal
595 Wrist Fracture 496 1.8 1.8 no signal
596 Adverse Drug Reaction 3,699 1.8 1.8 no signal
597 Agranulocytosis 764 1.8 1.8 no signal
598 Bedridden 539 1.8 1.8 no signal
599 Hidradenitis 356 1.8 1.8 no signal
600 Anaphylactic Reaction 2,248 1.8 1.8 no signal
601 Intestinal Perforation 459 1.8 1.8 no signal
602 Pulmonary Congestion 540 1.8 1.8 no signal
603 Blood Pressure Increased 6,235 1.8 1.8 no signal
604 Injection Site Urticaria 984 1.8 1.8 no signal
605 Weight Decreased 11,258 1.8 1.8 no signal
606 Injection Site Extravasation 501 1.8 1.8 no signal
607 Abdominal Pain 9,310 1.8 1.8 no signal
608 Upper Limb Fracture 800 1.8 1.8 no signal
609 Impaired Quality Of Life 574 1.8 1.8 no signal
610 Eye Disorder 1,303 1.8 1.8 no signal
611 Muscle Strain 343 1.8 1.8 no signal
612 Myopathy 344 1.8 1.8 no signal
613 Malaise 17,268 1.7 1.8 no signal
614 Post Procedural Complication 755 1.7 1.7 no signal
615 White Blood Cell Count Increased 1,499 1.7 1.7 no signal
616 Abdominal Pain Upper 7,976 1.7 1.7 no signal
617 Rectal Haemorrhage 1,663 1.7 1.7 no signal
618 Gastrooesophageal Reflux Disease 3,090 1.7 1.7 no signal
619 Drug Resistance 986 1.7 1.7 no signal
620 Thyroid Disorder 591 1.7 1.7 no signal
621 Deafness 1,002 1.7 1.7 no signal
622 Cholelithiasis 1,251 1.7 1.7 no signal
623 Small Intestinal Obstruction 468 1.7 1.7 no signal
624 Pericardial Effusion 877 1.7 1.7 no signal
625 Affect Lability 368 1.7 1.7 no signal
626 Laceration 361 1.7 1.7 no signal
627 Movement Disorder 1,220 1.7 1.7 no signal
628 Fracture 712 1.7 1.7 no signal
629 Diabetes Mellitus 2,877 1.7 1.7 no signal
630 Rib Fracture 770 1.7 1.7 no signal
631 Pancreatitis 1,983 1.7 1.7 no signal
632 Neuralgia 907 1.6 1.6 no signal
633 Spinal Fracture 741 1.6 1.6 no signal
634 Headache 23,243 1.6 1.7 no signal
635 Cholecystitis 441 1.6 1.6 no signal
636 Inflammatory Bowel Disease 365 1.6 1.6 no signal
637 Vomiting 17,356 1.6 1.7 no signal
638 Conjunctivitis 676 1.6 1.6 no signal
639 Hysterectomy 317 1.6 1.6 no signal
640 Hypophagia 930 1.6 1.6 no signal
641 Respiratory Syncytial Virus Infection 317 1.6 1.6 no signal
642 Pain In Jaw 1,036 1.6 1.6 no signal
643 Nausea 28,656 1.6 1.6 no signal
644 Scratch 376 1.6 1.6 no signal
645 Dry Eye 1,759 1.6 1.6 no signal
646 Hypertensive Crisis 405 1.6 1.6 no signal
647 Haemorrhoids 704 1.6 1.6 no signal
648 Tooth Extraction 448 1.6 1.6 no signal
649 Asthma 4,019 1.6 1.6 no signal
650 Colon Cancer 531 1.6 1.6 no signal
651 Blood Bilirubin Increased 961 1.6 1.6 no signal
652 Medication Error 1,964 1.6 1.6 no signal
653 Heart Rate Irregular 804 1.6 1.6 no signal
654 Dermatitis 732 1.6 1.6 no signal
655 Injection Site Haemorrhage 2,796 1.5 1.6 no signal
656 Cholestasis 669 1.5 1.5 no signal
657 Oesophagitis 383 1.5 1.5 no signal
658 Anaemia 6,674 1.5 1.5 no signal
659 Flank Pain 327 1.5 1.5 no signal
660 Sneezing 780 1.5 1.5 no signal
661 Photophobia 651 1.5 1.5 no signal
662 Haematocrit Decreased 696 1.5 1.5 no signal
663 Chest Pain 6,461 1.5 1.5 no signal
664 Petechiae 361 1.5 1.5 no signal
665 Acute Respiratory Failure 664 1.5 1.5 no signal
666 Paraesthesia 5,422 1.5 1.5 no signal
667 Quality Of Life Decreased 460 1.5 1.5 no signal
668 Brain Oedema 432 1.5 1.5 no signal
669 Covid-19 6,051 1.5 1.5 no signal
670 Eating Disorder 731 1.5 1.5 no signal
671 Neoplasm 392 1.5 1.5 no signal
672 Optic Neuritis 310 1.5 1.5 no signal
673 Sleep Apnoea Syndrome 645 1.5 1.5 no signal
674 Ascites 987 1.5 1.5 no signal
675 Amnesia 2,190 1.5 1.5 no signal
676 Accident 399 1.5 1.5 no signal
677 Toxic Epidermal Necrolysis 505 1.5 1.5 no signal
678 Adverse Event 3,085 1.5 1.5 no signal
679 Osteonecrosis 1,108 1.5 1.5 no signal
680 Renal Impairment 2,793 1.5 1.5 no signal
681 Mitral Valve Incompetence 375 1.5 1.5 no signal
682 Spinal Operation 401 1.5 1.5 no signal
683 Coronary Artery Occlusion 456 1.5 1.5 no signal
684 Seasonal Allergy 467 1.5 1.5 no signal
685 Angina Pectoris 953 1.4 1.4 no signal
686 Deep Vein Thrombosis 2,147 1.4 1.4 no signal
687 Gamma-glutamyltransferase Increased 728 1.4 1.4 no signal
688 Hypokinesia 476 1.4 1.4 no signal
689 Pruritus 12,368 1.4 1.4 no signal
690 Disease Progression 3,848 1.4 1.4 no signal
691 Influenza Like Illness 2,692 1.4 1.4 no signal
692 Feeding Disorder 649 1.4 1.4 no signal
693 Blood Creatinine Increased 2,126 1.4 1.4 no signal
694 Aphasia 982 1.4 1.4 no signal
695 Hepatic Failure 978 1.4 1.4 no signal
696 Gallbladder Disorder 579 1.4 1.4 no signal
697 Inappropriate Schedule Of Product Administration 5,716 1.4 1.4 no signal
698 Rebound Effect 366 1.4 1.4 no signal
699 Diarrhoea 20,703 1.4 1.4 no signal
700 Body Height Decreased 348 1.4 1.4 no signal
701 Cholecystectomy 365 1.4 1.4 no signal
702 Malnutrition 356 1.4 1.4 no signal
703 Toxicity To Various Agents 5,334 1.4 1.4 no signal
704 Scar 541 1.4 1.4 no signal
705 Fall 10,447 1.4 1.4 no signal
706 Asthenia 11,795 1.4 1.4 no signal
707 Pulmonary Embolism 2,989 1.4 1.4 no signal
708 White Blood Cell Count Decreased 3,393 1.4 1.4 no signal
709 Respiratory Distress 858 1.4 1.4 no signal
710 Ear Discomfort 318 1.4 1.4 no signal
711 Feeling Hot 1,902 1.4 1.4 no signal
712 Aphonia 431 1.4 1.4 no signal
713 Hyperlipidaemia 369 1.3 1.3 no signal
714 Brain Neoplasm 282 1.3 1.3 no signal
715 Nephropathy 287 1.3 1.3 no signal
716 Haemoglobin Decreased 3,144 1.3 1.3 no signal
717 Neutrophil Count Decreased 1,234 1.3 1.3 no signal
718 Obstructive Airways Disorder 339 1.3 1.3 no signal
719 Rash Erythematous 1,422 1.3 1.3 no signal
720 Generalised Oedema 373 1.3 1.3 no signal
721 Neutrophil Count Increased 311 1.3 1.3 no signal
722 Injection Site Nodule 332 1.3 1.3 no signal
723 Erythema 6,183 1.3 1.3 no signal
724 Ileus 370 1.3 1.3 no signal
725 Sars-cov-2 Test Positive 401 1.3 1.3 no signal
726 Pancreatitis Acute 668 1.3 1.3 no signal
727 Chills 3,474 1.3 1.3 no signal
728 Cardiomegaly 366 1.3 1.3 no signal
729 Poor Quality Sleep 631 1.3 1.3 no signal
730 Laboratory Test Abnormal 869 1.3 1.3 no signal
731 Depression 6,729 1.3 1.3 no signal
732 Acute Kidney Injury 4,482 1.3 1.3 no signal
733 No Therapeutic Response 364 1.3 1.3 no signal
734 Atrial Fibrillation 2,867 1.3 1.3 no signal
735 Retinal Detachment 270 1.3 1.3 no signal
736 Insomnia 7,824 1.3 1.3 no signal
737 Decreased Appetite 6,769 1.3 1.3 no signal
738 Metastases To Lung 337 1.3 1.3 no signal
739 Memory Impairment 4,003 1.3 1.3 no signal
740 Rash Papular 653 1.3 1.3 no signal
741 Gout 521 1.3 1.3 no signal
742 Illness 2,912 1.3 1.3 no signal
743 Injection Site Discomfort 299 1.3 1.3 no signal
744 Cardiomyopathy 426 1.3 1.3 no signal
745 Drug Interaction 4,567 1.3 1.3 no signal
746 Skin Discolouration 1,322 1.3 1.3 no signal
747 Dyspnoea 16,270 1.3 1.3 no signal
748 Rash Maculo-papular 637 1.3 1.3 no signal
749 Dyspnoea Exertional 1,078 1.3 1.3 no signal
750 Nervous System Disorder 898 1.3 1.3 no signal
751 Red Blood Cell Count Decreased 819 1.2 1.2 no signal
752 Oral Discomfort 398 1.2 1.2 no signal
753 Hypokalaemia 1,305 1.2 1.2 no signal
754 Throat Irritation 1,266 1.2 1.2 no signal
755 Hypoxia 992 1.2 1.2 no signal
756 Lung Neoplasm Malignant 1,168 1.2 1.2 no signal
757 Tachycardia 2,496 1.2 1.2 no signal
758 Impaired Gastric Emptying 358 1.2 1.2 no signal
759 Drug Toxicity 386 1.2 1.2 no signal
760 Chronic Obstructive Pulmonary Disease 1,444 1.2 1.2 no signal
761 Abdominal Distension 2,878 1.2 1.2 no signal
762 Acute Hepatic Failure 375 1.2 1.2 no signal
763 Hypothyroidism 876 1.2 1.2 no signal
764 Tachypnoea 371 1.2 1.2 no signal
765 Ataxia 326 1.2 1.2 no signal
766 Intestinal Obstruction 1,024 1.2 1.2 no signal
767 Lymphocyte Count Decreased 483 1.2 1.2 no signal
768 Dry Throat 277 1.2 1.2 no signal
769 Bone Density Decreased 861 1.2 1.2 no signal
770 Renal Disorder 1,268 1.2 1.2 no signal
771 Blood Urine Present 517 1.2 1.2 no signal
772 Pharyngeal Oedema 423 1.2 1.2 no signal
773 Epistaxis 2,021 1.2 1.2 no signal
774 Muscle Spasms 4,948 1.2 1.2 no signal
775 Macular Degeneration 321 1.2 1.2 no signal
776 Leukaemia 253 1.2 1.2 no signal
777 Renal Pain 282 1.2 1.2 no signal
778 Renal Tubular Necrosis 262 1.2 1.2 no signal
779 Electrolyte Imbalance 306 1.2 1.2 no signal
780 Skin Fissures 502 1.2 1.2 no signal
781 Sleep Disorder Due To A General Medical Condition 429 1.2 1.2 no signal
782 Pain Of Skin 714 1.2 1.2 no signal
783 Pulmonary Oedema 1,185 1.2 1.2 no signal
784 Blindness Unilateral 372 1.2 1.2 no signal
785 Gingival Bleeding 361 1.1 1.1 no signal
786 Dysphonia 1,541 1.1 1.1 no signal
787 Product Prescribing Error 624 1.1 1.1 no signal
788 Abasia 660 1.1 1.1 no signal
789 Renal Failure 3,521 1.1 1.1 no signal
790 Heart Rate Increased 2,595 1.1 1.1 no signal
791 Surgery 1,513 1.1 1.1 no signal
792 Ovarian Cancer 241 1.1 1.1 no signal
793 Peripheral Coldness 357 1.1 1.1 no signal
794 Dysarthria 967 1.1 1.1 no signal
795 Muscle Atrophy 323 1.1 1.1 no signal
796 Burning Sensation 1,797 1.1 1.1 no signal
797 Metastases To Liver 449 1.1 1.1 no signal
798 Visual Impairment 3,142 1.1 1.1 no signal
799 Neoplasm Malignant 1,701 1.1 1.1 no signal
800 Hypocalcaemia 481 1.1 1.1 no signal
801 Anorexia 333 1.1 1.1 no signal
802 Vertigo 1,549 1.1 1.1 no signal
803 Dysuria 935 1.1 1.1 no signal
804 Neuropathy Peripheral 2,397 1.1 1.1 no signal
805 Coordination Abnormal 356 1.1 1.1 no signal
806 Blood Alkaline Phosphatase Increased 630 1.1 1.1 no signal
807 Procedural Pain 699 1.1 1.1 no signal
808 Leukocytosis 457 1.1 1.1 no signal
809 Incontinence 267 1.1 1.1 no signal
810 Inappropriate Antidiuretic Hormone Secretion 256 1.1 1.1 no signal
811 Activities Of Daily Living Impaired 505 1.1 1.1 no signal
812 Thrombosis 2,022 1.1 1.1 no signal
813 Pharyngeal Swelling 239 1.1 1.1 no signal
814 Bladder Disorder 247 1.1 1.1 no signal
815 Cytokine Release Syndrome 471 1.1 1.1 no signal
816 Pallor 673 1.1 1.1 no signal
817 Feeling Cold 686 1.1 1.1 no signal
818 Abdominal Pain Lower 623 1.1 1.1 no signal
819 Platelet Count Decreased 2,614 1.1 1.1 no signal
820 Accidental Overdose 896 1.1 1.1 no signal
821 Ejection Fraction Decreased 381 1.1 1.1 no signal
822 Supraventricular Tachycardia 234 1.1 1.1 no signal
823 Transient Ischaemic Attack 829 1.1 1.1 no signal
824 Haematuria 839 1.1 1.1 no signal
825 Blood Pressure Abnormal 479 1.1 1.1 no signal
826 Intentional Dose Omission 660 1.0 1.0 no signal
827 Haemoptysis 674 1.0 1.0 no signal
828 Chest Discomfort 2,456 1.0 1.0 no signal
829 Cerebral Infarction 587 1.0 1.0 no signal
830 Myocardial Ischaemia 275 1.0 1.0 no signal
831 Paralysis 344 1.0 1.0 no signal
832 Tubulointerstitial Nephritis 448 1.0 1.0 no signal
833 Rash Macular 832 1.0 1.0 no signal
834 Thyroid Cancer 288 1.0 1.0 no signal
835 Wrong Technique In Drug Usage Process 874 1.0 1.0 no signal
836 Cardiac Failure 1,901 1.0 1.0 no signal
837 Dizziness 11,759 1.0 1.0 no signal
838 Hip Fracture 756 1.0 1.0 no signal
839 Sinus Tachycardia 332 1.0 1.0 no signal
840 Intraocular Pressure Increased 300 1.0 1.0 no signal
841 Dysphagia 2,203 1.0 1.0 no signal
842 Swelling Face 1,499 1.0 1.0 no signal
843 Eye Haemorrhage 308 1.0 1.0 no signal
844 Renal Failure Acute 987 1.0 1.0 no signal
845 Coronary Artery Disease 699 1.0 1.0 no signal
846 Haematoma 593 1.0 1.0 no signal
847 Diplopia 591 1.0 1.0 no signal
848 Bone Pain 1,332 1.0 1.0 no signal
849 Pruritus Generalised 498 1.0 1.0 no signal
850 Shock 514 1.0 1.0 no signal
851 Mental Status Changes 626 1.0 1.0 no signal
852 Hypotension 4,498 1.0 1.0 no signal
853 Peritonitis 465 1.0 1.0 no signal
854 Subarachnoid Haemorrhage 229 1.0 1.0 no signal
855 Vitreous Floaters 218 1.0 1.0 no signal
856 Grand Mal Convulsion 209 1.0 1.0 no signal
857 Subdural Haematoma 316 1.0 1.0 no signal
858 Pulmonary Hypertension 458 0.9 0.9 no signal
859 Glomerular Filtration Rate Decreased 265 0.9 0.9 no signal
860 Eosinophilia 382 0.9 0.9 no signal
861 Osteonecrosis Of Jaw 543 0.9 0.9 no signal
862 Swollen Tongue 681 0.9 0.9 no signal
863 Blood Potassium Decreased 655 0.9 0.9 no signal
864 Proteinuria 410 0.9 0.9 no signal
865 Blood Urea Increased 366 0.9 0.9 no signal
866 Eyelid Ptosis 221 0.9 0.9 no signal
867 Myalgia 3,692 0.9 0.9 no signal
868 Sensory Disturbance 350 0.9 0.9 no signal
869 Skin Exfoliation 1,802 0.9 0.9 no signal
870 Blood Pressure Decreased 1,434 0.9 0.9 no signal
871 Blood Triglycerides Increased 383 0.9 0.9 no signal
872 Urinary Incontinence 639 0.9 0.9 no signal
873 Acute Myocardial Infarction 636 0.9 0.9 no signal
874 Device Malfunction 1,440 0.9 0.9 no signal
875 Lacrimation Increased 640 0.9 0.9 no signal
876 Fluid Retention 1,089 0.9 0.9 no signal
877 Loss Of Consciousness 2,728 0.9 0.9 no signal
878 Breast Cancer 1,987 0.9 0.9 no signal
879 Haematemesis 536 0.9 0.9 no signal
880 Temperature Intolerance 214 0.9 0.9 no signal
881 Haemorrhage 2,186 0.9 0.9 no signal
882 Eye Pain 1,154 0.9 0.9 no signal
883 Eye Discharge 213 0.9 0.9 no signal
884 Multiple Fractures 344 0.9 0.9 no signal
885 Blindness 845 0.9 0.9 no signal
886 Tinnitus 954 0.9 0.9 no signal
887 Arteriosclerosis 194 0.9 0.9 no signal
888 Middle Insomnia 382 0.9 0.9 no signal
889 Haemorrhage Intracranial 308 0.9 0.9 no signal
890 Head Discomfort 361 0.9 0.9 no signal
891 Hyperglycaemia 743 0.9 0.9 no signal
892 Toxic Skin Eruption 206 0.9 0.9 no signal
893 Jaundice 549 0.9 0.9 no signal
894 Myocarditis 230 0.9 0.9 no signal
895 Full Blood Count Abnormal 214 0.9 0.9 no signal
896 Feeling Abnormal 4,862 0.9 0.9 no signal
897 Gastric Haemorrhage 231 0.9 0.9 no signal
898 Eczema 989 0.9 0.8 no signal
899 Dermatitis Contact 223 0.8 0.8 no signal
900 Anxiety 5,566 0.8 0.8 no signal
901 Lethargy 1,120 0.8 0.8 no signal
902 Incorrect Product Storage 258 0.8 0.8 no signal
903 Arrhythmia 918 0.8 0.8 no signal
904 Palpitations 2,258 0.8 0.8 no signal
905 Syncope 1,931 0.8 0.8 no signal
906 Status Epilepticus 218 0.8 0.8 no signal
907 Decreased Activity 206 0.8 0.8 no signal
908 Presyncope 465 0.8 0.8 no signal
909 Generalised Tonic-clonic Seizure 314 0.8 0.8 no signal
910 Underdose 1,402 0.8 0.8 no signal
911 Face Oedema 323 0.8 0.8 no signal
912 Micturition Urgency 216 0.8 0.8 no signal
913 Head Injury 601 0.8 0.8 no signal
914 Central Nervous System Lesion 260 0.8 0.8 no signal
915 Cold Sweat 331 0.8 0.8 no signal
916 Hyperhidrosis 2,415 0.8 0.8 no signal
917 Throat Tightness 505 0.8 0.8 no signal
918 Restless Legs Syndrome 338 0.8 0.8 no signal
919 Anaphylactic Shock 475 0.8 0.8 no signal
920 Rash Generalised 482 0.8 0.8 no signal
921 Ischaemic Stroke 328 0.8 0.8 no signal
922 Dehydration 2,428 0.8 0.8 no signal
923 Cyanosis 284 0.8 0.8 no signal
924 Gastrointestinal Haemorrhage 1,515 0.8 0.8 no signal
925 Unevaluable Event 1,360 0.8 0.8 no signal
926 Bronchospasm 257 0.8 0.8 no signal
927 Blood Sodium Decreased 337 0.8 0.8 no signal
928 Metastases To Central Nervous System 229 0.8 0.8 no signal
929 Incorrect Dose Administered 4,020 0.8 0.8 no signal
930 Depressed Mood 938 0.8 0.8 no signal
931 Pollakiuria 741 0.8 0.8 no signal
932 Breast Cancer Metastatic 190 0.8 0.8 no signal
933 Cerebral Haemorrhage 633 0.8 0.8 no signal
934 Breast Pain 188 0.8 0.8 no signal
935 Blood Potassium Increased 286 0.8 0.8 no signal
936 Metastases To Bone 288 0.8 0.8 no signal
937 Injection Site Mass 646 0.8 0.8 no signal
938 Faeces Discoloured 377 0.8 0.8 no signal
939 Ocular Hyperaemia 811 0.7 0.7 no signal
940 Melaena 382 0.7 0.7 no signal
941 Myocardial Infarction 3,040 0.7 0.7 no signal
942 Aspiration 187 0.7 0.7 no signal
943 Circulatory Collapse 294 0.7 0.7 no signal
944 Hypersomnia 492 0.7 0.7 no signal
945 Hepatitis C 209 0.7 0.7 no signal
946 Needle Issue 484 0.7 0.7 no signal
947 Hypoacusis 724 0.7 0.7 no signal
948 Hyponatraemia 945 0.7 0.7 no signal
949 Treatment Noncompliance 906 0.7 0.7 no signal
950 Visual Acuity Reduced 555 0.7 0.7 no signal
951 Product Prescribing Issue 336 0.7 0.7 no signal
952 Hot Flush 1,244 0.7 0.7 no signal
953 Upper Gastrointestinal Haemorrhage 278 0.7 0.7 no signal
954 Urinary Retention 548 0.7 0.7 no signal
955 Sudden Death 176 0.7 0.7 no signal
956 Crying 599 0.7 0.7 no signal
957 Blood Count Abnormal 252 0.7 0.7 no signal
958 Tooth Loss 342 0.7 0.7 no signal
959 Lip Swelling 544 0.7 0.7 no signal
960 Cerebrovascular Accident 2,783 0.7 0.7 no signal
961 Eye Swelling 605 0.7 0.7 no signal
962 Speech Disorder 857 0.7 0.7 no signal
963 Neoplasm Progression 574 0.7 0.7 no signal
964 Cardiac Failure Congestive 1,321 0.7 0.7 no signal
965 Hepatic Encephalopathy 152 0.7 0.7 no signal
966 Ventricular Extrasystoles 169 0.7 0.7 no signal
967 Pneumonia Aspiration 404 0.7 0.7 no signal
968 Post Procedural Haemorrhage 189 0.7 0.7 no signal
969 Cardiac Disorder 1,519 0.7 0.7 no signal
970 Brain Injury 162 0.7 0.7 no signal
971 Seizure 1,851 0.7 0.7 no signal
972 Diabetes Mellitus Inadequate Control 285 0.7 0.7 no signal
973 Balance Disorder 1,393 0.7 0.7 no signal
974 Ventricular Fibrillation 179 0.7 0.7 no signal
975 Drug Effect Less Than Expected 226 0.7 0.7 no signal
976 Paraesthesia Oral 229 0.7 0.7 no signal
977 Vaginal Discharge 160 0.7 0.7 no signal
978 Nervousness 836 0.7 0.7 no signal
979 Ventricular Tachycardia 263 0.7 0.7 no signal
980 Muscle Tightness 256 0.7 0.7 no signal
981 Nocturia 191 0.7 0.7 no signal
982 Device Issue 1,372 0.7 0.7 no signal
983 Dizziness Postural 151 0.7 0.7 no signal
984 Stevens-johnson Syndrome 350 0.7 0.7 no signal
985 Blood Calcium Decreased 176 0.7 0.7 no signal
986 Intentional Product Misuse 1,343 0.7 0.7 no signal
987 Inappropriate Schedule Of Drug Administration 1,115 0.7 0.7 no signal
988 Blood Creatine Phosphokinase Increased 450 0.7 0.7 no signal
989 Altered State Of Consciousness 331 0.7 0.7 no signal
990 Pelvic Pain 279 0.7 0.7 no signal
991 Transfusion 161 0.7 0.7 no signal
992 Cardiovascular Disorder 391 0.7 0.7 no signal
993 Brain Fog 223 0.7 0.7 no signal
994 Drug Dose Omission 2,555 0.7 0.7 no signal
995 Eyelid Oedema 178 0.7 0.7 no signal
996 Flatulence 860 0.7 0.7 no signal
997 Hypoaesthesia Oral 228 0.7 0.7 no signal
998 Angioedema 667 0.7 0.6 no signal
999 Vision Blurred 2,054 0.6 0.6 no signal
1000 Ocular Discomfort 162 0.6 0.6 no signal
1001 Drug Effective For Unapproved Indication 434 0.6 0.6 no signal
1002 Metabolic Acidosis 466 0.6 0.6 no signal
1003 Initial Insomnia 150 0.6 0.6 no signal
1004 Convulsion 853 0.6 0.6 no signal
1005 Bipolar Disorder 161 0.6 0.6 no signal
1006 Infusion Site Pain 187 0.6 0.6 no signal
1007 Dementia 407 0.6 0.6 no signal
1008 Somnolence 2,931 0.6 0.6 no signal
1009 Acne 1,110 0.6 0.6 no signal
1010 Coma 692 0.6 0.6 no signal
1011 Therapeutic Response Unexpected 650 0.6 0.6 no signal
1012 Hypomagnesaemia 200 0.6 0.6 no signal
1013 Retching 305 0.6 0.6 no signal
1014 Mental Disorder 625 0.6 0.6 no signal
1015 Eye Pruritus 472 0.6 0.6 no signal
1016 Thirst 255 0.6 0.6 no signal
1017 Sluggishness 145 0.6 0.6 no signal
1018 Disorientation 563 0.6 0.6 no signal
1019 Cardiogenic Shock 202 0.6 0.6 no signal
1020 Chronic Kidney Disease 1,079 0.6 0.6 no signal
1021 Product Administration Error 280 0.6 0.6 no signal
1022 Product Dose Omission In Error 376 0.6 0.6 no signal
1023 Hypotonia 140 0.6 0.6 no signal
1024 Breast Cancer Female 375 0.6 0.6 no signal
1025 Abortion Spontaneous 551 0.6 0.6 no signal
1026 Tremor 2,272 0.6 0.6 no signal
1027 Erythema Multiforme 127 0.6 0.6 no signal
1028 Constipation 2,942 0.6 0.6 no signal
1029 Apathy 197 0.6 0.6 no signal
1030 Cardiac Arrest 1,123 0.6 0.6 no signal
1031 Pulmonary Arterial Hypertension 197 0.6 0.6 no signal
1032 Abortion Induced 126 0.6 0.6 no signal
1033 Internal Haemorrhage 153 0.6 0.6 no signal
1034 Cognitive Disorder 620 0.6 0.6 no signal
1035 Fluid Overload 196 0.6 0.6 no signal
1036 Emotional Disorder 410 0.6 0.6 no signal
1037 Product Availability Issue 295 0.6 0.6 no signal
1038 Panic Attack 480 0.6 0.6 no signal
1039 Chromaturia 297 0.6 0.6 no signal
1040 Product Dose Omission 859 0.6 0.6 no signal
1041 Hyperthyroidism 187 0.6 0.6 no signal
1042 Product Dispensing Error 281 0.6 0.6 no signal
1043 Choking 248 0.5 0.5 no signal
1044 Menorrhagia 254 0.5 0.5 no signal
1045 Flushing 1,294 0.5 0.5 no signal
1046 Anosmia 183 0.5 0.5 no signal
1047 Mental Impairment 305 0.5 0.5 no signal
1048 Vaginal Haemorrhage 535 0.5 0.5 no signal
1049 Malignant Neoplasm Progression 1,271 0.5 0.5 no signal
1050 Full Blood Count Decreased 251 0.5 0.5 no signal
1051 Poisoning 156 0.5 0.5 no signal
1052 Unresponsive To Stimuli 316 0.5 0.5 no signal
1053 Depressed Level Of Consciousness 479 0.5 0.5 no signal
1054 Injury Associated With Device 244 0.5 0.5 no signal
1055 Therapy Interrupted 836 0.5 0.5 no signal
1056 Mood Swings 382 0.5 0.5 no signal
1057 Hypoglycaemia 581 0.5 0.5 no signal
1058 Ageusia 299 0.5 0.5 no signal
1059 Device Failure 180 0.5 0.5 no signal
1060 Hypothermia 120 0.5 0.5 no signal
1061 Blood Glucose Abnormal 218 0.5 0.5 no signal
1062 Cardio-respiratory Arrest 493 0.5 0.5 no signal
1063 Fear 317 0.5 0.5 no signal
1064 Blood Thyroid Stimulating Hormone Increased 108 0.5 0.5 no signal
1065 Hunger 157 0.5 0.5 no signal
1066 Dialysis 166 0.5 0.5 no signal
1067 Feeling Jittery 222 0.5 0.5 no signal
1068 Gastrointestinal Carcinoma 106 0.5 0.5 no signal
1069 Dysgeusia 862 0.5 0.5 no signal
1070 Bone Loss 175 0.5 0.5 no signal
1071 Product Dose Omission Issue 3,266 0.5 0.5 no signal
1072 Dry Skin 1,455 0.5 0.5 no signal
1073 Prostate Cancer 882 0.5 0.5 no signal
1074 Foetal Exposure During Pregnancy 881 0.5 0.5 no signal
1075 Therapy Cessation 552 0.5 0.5 no signal
1076 Bradycardia 573 0.5 0.5 no signal
1077 Psychotic Disorder 318 0.5 0.5 no signal
1078 Increased Appetite 202 0.5 0.5 no signal
1079 Impaired Driving Ability 120 0.5 0.5 no signal
1080 Suicidal Ideation 965 0.5 0.5 no signal
1081 Multiple Sclerosis 501 0.4 0.4 no signal
1082 Disturbance In Attention 558 0.4 0.4 no signal
1083 Personality Change 96 0.4 0.4 no signal
1084 Orthostatic Hypotension 179 0.4 0.4 no signal
1085 Mood Altered 278 0.4 0.4 no signal
1086 Eye Irritation 566 0.4 0.4 no signal
1087 Amenorrhoea 168 0.4 0.4 no signal
1088 Meningioma 148 0.4 0.4 no signal
1089 Hospitalisation 1,523 0.4 0.4 no signal
1090 Irritability 596 0.4 0.4 no signal
1091 Insurance Issue 146 0.4 0.4 no signal
1092 International Normalised Ratio Increased 279 0.4 0.4 no signal
1093 Overdose 2,079 0.4 0.4 no signal
1094 Prostatic Specific Antigen Increased 132 0.4 0.4 no signal
1095 Nightmare 326 0.4 0.4 no signal
1096 Muscle Rigidity 112 0.4 0.4 no signal
1097 Premature Baby 282 0.4 0.4 no signal
1098 Palmar-plantar Erythrodysaesthesia Syndrome 218 0.4 0.4 no signal
1099 Respiratory Arrest 257 0.4 0.4 no signal
1100 Product Quality Issue 1,236 0.4 0.4 no signal
1101 Complication Associated With Device 121 0.4 0.4 no signal
1102 Dyskinesia 364 0.4 0.4 no signal
1103 Thinking Abnormal 168 0.4 0.4 no signal
1104 Drug Reaction With Eosinophilia And Systemic Symptoms 227 0.4 0.4 no signal
1105 Hair Texture Abnormal 119 0.4 0.4 no signal
1106 Blood Glucose Increased 1,635 0.4 0.4 no signal
1107 Incorrect Product Administration Duration 175 0.4 0.4 no signal
1108 Muscle Twitching 198 0.4 0.4 no signal
1109 Gastric Cancer 218 0.4 0.4 no signal
1110 Glycosylated Haemoglobin Increased 214 0.4 0.4 no signal
1111 Sinus Bradycardia 82 0.4 0.4 no signal
1112 Hyperkalaemia 294 0.4 0.4 no signal
1113 Drug Prescribing Error 163 0.4 0.4 no signal
1114 Restlessness 305 0.4 0.4 no signal
1115 Pancreatic Carcinoma 240 0.4 0.4 no signal
1116 Sexual Dysfunction 96 0.4 0.4 no signal
1117 Myoclonus 98 0.4 0.4 no signal
1118 Mydriasis 105 0.4 0.3 no signal
1119 Premature Delivery 131 0.3 0.3 no signal
1120 Agitation 598 0.3 0.3 no signal
1121 Renal Injury 243 0.3 0.3 no signal
1122 Eructation 153 0.3 0.3 no signal
1123 Drug Administration Error 250 0.3 0.3 no signal
1124 Drug Exposure During Pregnancy 277 0.3 0.3 no signal
1125 Therapy Change 77 0.3 0.3 no signal
1126 Lactic Acidosis 255 0.3 0.3 no signal
1127 Device Defective 127 0.3 0.3 no signal
1128 Drug Dispensing Error 120 0.3 0.3 no signal
1129 Psychomotor Hyperactivity 128 0.3 0.3 no signal
1130 Euphoric Mood 79 0.3 0.3 no signal
1131 Wrong Technique In Product Usage Process 1,528 0.3 0.3 no signal
1132 Salivary Hypersecretion 75 0.3 0.3 no signal
1133 Accidental Exposure To Product 730 0.3 0.3 no signal
1134 Blood Glucose Decreased 351 0.3 0.3 no signal
1135 Breast Cancer Stage I 68 0.3 0.3 no signal
1136 Device Occlusion 100 0.3 0.3 no signal
1137 Delusion 111 0.3 0.3 no signal
1138 Skin Burning Sensation 508 0.3 0.3 no signal
1139 Skin Irritation 326 0.3 0.3 no signal
1140 Dysmenorrhoea 92 0.3 0.3 no signal
1141 Anger 238 0.3 0.3 no signal
1142 Skeletal Injury 73 0.3 0.3 no signal
1143 Hallucination 518 0.3 0.3 no signal
1144 Hallucination, Auditory 109 0.3 0.3 no signal
1145 Hallucination, Visual 143 0.3 0.3 no signal
1146 Incorrect Route Of Drug Administration 246 0.3 0.3 no signal
1147 Death 5,709 0.3 0.3 no signal
1148 Plasma Cell Myeloma 258 0.3 0.3 no signal
1149 Product Storage Error 567 0.3 0.3 no signal
1150 Diabetic Ketoacidosis 155 0.3 0.3 no signal
1151 Libido Decreased 80 0.3 0.3 no signal
1152 Bladder Cancer 382 0.3 0.3 no signal
1153 Madarosis 75 0.3 0.3 no signal
1154 Caesarean Section 75 0.3 0.3 no signal
1155 No Adverse Event 1,121 0.3 0.3 no signal
1156 Syringe Issue 110 0.3 0.3 no signal
1157 End Stage Renal Disease 115 0.3 0.3 no signal
1158 Device Dislocation 270 0.3 0.3 no signal
1159 Suicide Attempt 376 0.3 0.3 no signal
1160 Product Packaging Issue 57 0.3 0.3 no signal
1161 Metrorrhagia 105 0.3 0.3 no signal
1162 Erectile Dysfunction 156 0.3 0.3 no signal
1163 Drug Administered At Inappropriate Site 64 0.3 0.3 no signal
1164 Schizophrenia 71 0.2 0.2 no signal
1165 Oesophageal Carcinoma 172 0.2 0.2 no signal
1166 Incorrect Dose Administered By Device 145 0.2 0.2 no signal
1167 Electrocardiogram Qt Prolonged 205 0.2 0.2 no signal
1168 Hepatic Cancer 136 0.2 0.2 no signal
1169 Hereditary Angioedema 58 0.2 0.2 no signal
1170 Dermatitis Atopic 274 0.2 0.2 no signal
1171 Aggression 272 0.2 0.2 no signal
1172 Serotonin Syndrome 102 0.2 0.2 no signal
1173 Rhabdomyolysis 221 0.2 0.2 no signal
1174 Abnormal Behaviour 211 0.2 0.2 no signal
1175 Hair Colour Changes 66 0.2 0.2 no signal
1176 Parkinsonism 51 0.2 0.2 no signal
1177 Emotional Distress 634 0.2 0.2 no signal
1178 Blood Glucose Fluctuation 57 0.2 0.2 no signal
1179 Mania 85 0.2 0.2 no signal
1180 Poor Quality Product Administered 52 0.2 0.2 no signal
1181 Paranoia 88 0.2 0.2 no signal
1182 Circumstance Or Information Capable Of Leading To Medication Error 169 0.2 0.2 no signal
1183 Product Complaint 125 0.2 0.2 no signal
1184 Renal Cancer 241 0.2 0.2 no signal
1185 Abnormal Dreams 136 0.2 0.2 no signal
1186 Menstruation Irregular 128 0.2 0.2 no signal
1187 Exposure Via Skin Contact 107 0.2 0.2 no signal
1188 Device Breakage 174 0.2 0.2 no signal
1189 Expired Product Administered 144 0.2 0.2 no signal
1190 Device Leakage 183 0.2 0.2 no signal
1191 Wrong Technique In Device Usage Process 194 0.2 0.2 no signal
1192 Withdrawal Syndrome 178 0.2 0.2 no signal
1193 Product Substitution Issue 241 0.2 0.2 no signal
1194 Dystonia 79 0.2 0.2 no signal
1195 Product Use Complaint 62 0.2 0.2 no signal
1196 Drug Dependence 639 0.2 0.2 no signal
1197 Menstruation Delayed 39 0.2 0.2 no signal
1198 Economic Problem 57 0.2 0.2 no signal
1199 Application Site Pain 81 0.2 0.2 no signal
1200 Respiratory Depression 45 0.2 0.2 no signal
1201 Device Deployment Issue 44 0.2 0.2 no signal
1202 Product Administered At Inappropriate Site 65 0.2 0.2 no signal
1203 Inability To Afford Medication 35 0.2 0.2 no signal
1204 Sedation 90 0.1 0.1 no signal
1205 Device Difficult To Use 228 0.1 0.1 no signal
1206 Product Packaging Quantity Issue 36 0.1 0.1 no signal
1207 Intentional Overdose 205 0.1 0.1 no signal
1208 Incorrect Drug Administration Duration 88 0.1 0.1 no signal
1209 Application Site Erythema 78 0.1 0.1 no signal
1210 Device Mechanical Issue 38 0.1 0.1 no signal
1211 Device Delivery System Issue 74 0.1 0.1 no signal
1212 Gynaecomastia 87 0.1 0.1 no signal
1213 Product Preparation Error 57 0.1 0.1 no signal
1214 Drug Abuse 226 0.1 0.1 no signal
1215 Unintended Pregnancy 27 0.1 0.1 no signal
1216 Anhedonia 68 0.1 0.1 no signal
1217 Extra Dose Administered 102 0.1 0.1 no signal
1218 Peritonitis Bacterial 25 0.1 0.1 no signal
1219 Pharmaceutical Product Complaint 65 0.1 0.1 no signal
1220 Intentional Drug Misuse 48 0.1 0.1 no signal
1221 Application Site Pruritus 51 0.1 0.1 no signal
1222 Genital Haemorrhage 29 0.1 0.1 no signal
1223 Intentional Self-injury 44 0.1 0.1 no signal
1224 Abnormal Weight Gain 27 0.1 0.1 no signal
1225 Device Use Error 72 0.1 0.1 no signal
1226 Drug Dose Omission By Device 160 0.1 0.1 no signal
1227 Sickle Cell Anaemia With Crisis 32 0.1 0.1 no signal
1228 Multiple Sclerosis Relapse 138 0.1 0.1 no signal
1229 Device Use Issue 32 0.1 0.1 no signal
1230 Akathisia 23 0.1 0.1 no signal
1231 Product Taste Abnormal 22 0.1 0.1 no signal
1232 Completed Suicide 134 0.1 0.1 no signal
1233 Extrapyramidal Disorder 39 0.1 0.1 no signal
1234 Hospice Care 15 0.1 0.1 no signal
1235 Poisoning Deliberate 14 0.1 0.1 no signal
1236 Tardive Dyskinesia 42 0.1 0.1 no signal
1237 Product Physical Issue 29 0.1 0.1 no signal
1238 Application Site Rash 20 0.1 0.1 no signal
1239 Sopor 19 0.1 0.1 no signal
1240 Drug Withdrawal Syndrome 118 0.1 0.1 no signal
1241 Product Odour Abnormal 13 0.1 0.1 no signal
1242 Colorectal Cancer 60 0.1 0.1 no signal
1243 Application Site Irritation 14 0.0 0.0 no signal
1244 Neuroleptic Malignant Syndrome 13 0.0 0.0 no signal
1245 Product Adhesion Issue 36 0.0 0.0 no signal
1246 Dependence 53 0.0 0.0 no signal
1247 Complication Of Device Insertion 16 0.0 0.0 no signal
1248 Accidental Underdose 12 0.0 0.0 no signal
1249 Embedded Device 6 0.0 0.0 no signal
1250 Complication Of Device Removal 9 0.0 0.0 no signal
1251 Device Adhesion Issue 7 0.0 0.0 no signal
1252 Unintentional Medical Device Removal 5 0.0 0.0 no signal
1253 Device Expulsion 14 0.0 0.0 no signal