Reaction

Blood Pressure Diastolic Abnormal reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,537 reports · 226 co-occurring drugs

As of the last recalculation, Blood Pressure Diastolic Abnormal appears in 2,537 FAERS reports alongside 226 co-occurring drug terms. The strongest observed disproportionality signal is DIPHENHYDRAMINE HYDROCHLORIDE CAPSULE, LIQUID FILLED (PRR 302.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Diphenhydramine Hydrochloride Capsule, Liquid Filled	601	302.1	310.9
Diphenhydramine Hydrochloride	1,766	285.3	288.3
Methylprednisolone Sodium Succinate	919	254.1	259.2
Methylprednisolone	1,504	217.8	220.2
Rituximab	1,522	146.1	147.2
Acetaminophen	1,876	129.1	129.7
Risedronate Sodium	326	98.6	99.6
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	1,097	98.4	99.0
Tocilizumab	891	98.2	99.0
Acetaminophen Tablet Extended Release	1,292	83.6	84.1
Pain Reliever	1,292	83.6	84.0
Acetaminophen 500Mg	1,292	83.6	84.0
Diphenhydramine	457	72.2	72.7
Dimenhydrinate	86	68.5	69.1
Rosuvastatin Calcium	177	55.3	55.7
Prednisone	1,433	52.4	52.6
Hydroxychloroquine Sulfate	453	49.4	49.7
Pantoprazole Sodium In 0.9% Sodium Chloride	294	43.9	44.1
Pantoprazole Sodium Injection	294	43.9	44.1
Desoximetasone	98	43.9	44.1
Folic Acid	853	41.8	41.9
Calcium	574	40.7	40.8
Diphenhydramine Hcl	52	39.1	39.3
Rabeprazole	94	36.1	36.3
Sulfasalazine	298	35.3	35.4
Telmisartan	68	32.1	32.2
Methotrexate	979	30.5	30.5
Irbesartan	153	29.8	29.9
Leflunomide	324	29.0	29.1
Methotrexate Sodium	1,029	28.5	28.6
Pantoprazole	638	27.3	27.4
Naproxen	236	27.1	27.2
Hydroxychloroquine	210	25.1	25.1
Dexlansoprazole	105	21.5	21.6
Nifedipine	114	20.7	20.8
Sulfamethoxazole And Trimethoprim	196	20.6	20.6
Esomeprazole	144	20.1	20.2
Indomethacin	32	20.1	20.1
Mycophenolate Mofetil	287	19.4	19.5
Alendronate Sodium	219	19.4	19.4
Mycophenolate Mofetil Hydrochloride	287	19.4	19.4
Dutasteride	19	19.3	19.4
Tramadol Hydrochloride	83	18.7	18.7
Azathioprine	186	18.6	18.6
Pantoprazole Sodium	295	18.3	18.4
Celecoxib	264	18.2	18.3
Epoetin Alfa	26	18.2	18.2
Mometasone	40	18.2	18.2
Instalax Polyethylene Glycol 3350	27	18.0	18.1
Polyethylene Glycol 400	27	17.6	17.7
Hydrocortisone Sodium Succinate	20	17.6	17.6
Cyclobenzaprine Hydrochloride	19	17.5	17.5
Ramipril	237	17.2	17.2
Dicyclomine Hydrochloride	29	16.9	16.9
Diltiazem Hydrochloride	69	16.8	16.8
Loperamide Hydrochloride And Dimethicone	64	16.8	16.8
Naproxen Sodium	262	16.7	16.7
Ciclesonide	26	15.8	15.8
Terazosin Hydrochloride	17	15.8	15.8
Pramipexole	29	15.7	15.7
Cannabidiol	44	15.7	15.7
Cetirizine Hydrochloride Allergy	56	15.5	15.5
Cetirizine Hydrochloride Tablets	56	15.5	15.5
Cyclobenzaprine	90	15.3	15.3
Iron	116	14.9	14.9
Candesartan	62	14.6	14.6
Standardized Senna Concentrate	22	14.5	14.5
Alendronate Sodium Tablet	32	14.3	14.4
Ibuprofen Tablets, Coated	70	13.9	13.9
Ibuprofen Sodium	70	13.8	13.8
Naproxen Sodium Tablet, Coated	22	13.4	13.5
Naproxen Sodium, Coated Tablets	22	13.4	13.5
Naproxen Sodium 220Mg	22	13.4	13.4
Clindamycin	45	13.2	13.2
Carboxymethylcellulose Sodium	15	13.2	13.2
Tolterodine Tartrate	14	12.9	12.9
Colchicine	40	12.6	12.7
Atorvastatin Calcium, Film Coated	104	12.6	12.7
Fluticasone Propionate And Salmeterol Xinafoate	89	12.6	12.6
Amiodarone Hydrochloride	17	12.5	12.5
Levothyroxine Sodium	406	12.4	12.4
Diclofenac	124	12.4	12.4
Calcium Gluconate	18	12.3	12.4
Docusate Sodium 100Mg	35	12.2	12.2
Quetiapine Fumarate	43	12.1	12.2
Loperamide Hydrochloride	64	12.0	12.0
Escitalopram Oxalate	100	11.7	11.7
Clindamycin Phosphate	45	11.2	11.2
Tranexamic Acid	12	11.1	11.1
Meloxicam	76	11.0	11.0
Venlafaxine	93	11.0	11.0
Valacyclovir	54	10.8	10.8
Oxazepam	28	10.8	10.8
Antacid	61	10.8	10.8
Escitslopram	73	10.6	10.6
Amlodipine	308	10.5	10.5
Mometasone Furoate	52	10.4	10.4
Hydrochlorothiazide	173	10.4	10.4
Vitamin C	111	10.3	10.3
Esomeprazole Magnesium Capsule, Delayed Release	18	10.2	10.3
Esomeprazole Magnesium Delayed Release Capsules	18	10.2	10.3
Fluticasone Furoate	15	10.2	10.2
Esomeprazole Magnesium Dihydrate	18	10.2	10.2
Acetaminophen And Codeine	15	10.2	10.2
Magnesium	96	9.9	9.9
Citalopram Hydrobromide	123	9.8	9.9
Docusate Sodium	67	9.8	9.8
Piperacillin Sodium,Tazobactam Sodium	30	9.4	9.4
Sucralfate Oral	16	9.3	9.3
Sucralfate Oral Suspension	16	9.3	9.3
Chlorthalidone	13	9.2	9.2
Bisoprolol Fumarate	145	9.2	9.2
Valacyclovir Hydrochloride	76	9.1	9.1
Docusate Sodium - Sennosides	34	8.8	8.8
Sitagliptin	74	8.6	8.7
Metformin Er 500 Mg	284	8.6	8.6
Metformin Er 750 Mg	284	8.6	8.6
Moxifloxacin Hydrochloride	21	8.6	8.6
Tamsulosin Hydrochloride	21	8.5	8.5
Misoprostol	10	8.5	8.5
Nitroglycerin	54	8.4	8.4
Piperacillin And Tazobactam	13	8.4	8.4
Cyanocobalamin	33	8.3	8.3
Canagliflozin	30	8.3	8.3
Ezetimibe	74	8.3	8.3
Doxazosin Mesylate	36	8.3	8.3
Rosuvastatin	192	8.2	8.3
Biotin	31	8.2	8.2
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	30	8.2	8.2
Atovaquone	8	8.2	8.2
Isoniazid	16	8.1	8.2
Citalopram	129	8.1	8.1
Azithromycin	39	8.1	8.1
Meperidine Hydrochloride	9	8.0	8.0
Morphine	71	8.0	8.0
Azithromycin Monohydrate	40	8.0	8.0
Diclofenac Sodium	139	8.0	8.0
Pertuzumab	26	7.9	7.9
Metformin	298	7.6	7.6
Atorvastatin Calcium	213	7.6	7.6
Calcium Carbonate	61	7.6	7.6
Brinzolamide	8	7.6	7.6
Mirabegron	35	7.5	7.5
Oxybutynin Chloride	8	7.5	7.5
Cetirizine	69	7.5	7.5
Pregabalin	228	7.5	7.5
Lorazepam	154	7.4	7.4
Valsartan Oral	48	7.4	7.4
Paroxetine Hydrochloride Hemihydrate	29	7.2	7.2
Drs. Clotrimazole	10	7.1	7.1
Family Wellness Clotrimazole	10	7.1	7.1
Clotrimazole Topical	10	7.1	7.1
Losartan Potassium And Hydrochlorothiazide	10	7.1	7.1
Paroxetine	29	7.1	7.1
Fenofibrate	30	7.0	7.0
Ticagrelor	27	7.0	7.0
Dalteparin Sodium	9	7.0	7.0
Ampicillin	7	7.0	7.0
Ampicillin Sodium	7	7.0	7.0
Amlodipine Besylate	118	6.9	6.9
Clotrimazole	10	6.7	6.7
Ciprofolxacin	57	6.7	6.7
Ciprofloxacin Tablets	57	6.7	6.7
Metoprolol Tartrate Injection	146	6.6	6.6
Venlafaxine Hydrochloride	103	6.6	6.6
0Xygen	39	6.6	6.6
Oxygen	39	6.6	6.6
Diltiazem Hydrochloride Extended-Release Tablets	9	6.5	6.5
Prednisolone Acetate	8	6.4	6.4
Sildenafil Powder,	27	6.3	6.3
Ketoprofen	10	6.3	6.3
Quinapril Hydrochloride	6	6.3	6.3
Azithromycin Dihydrate	44	6.2	6.2
Clonazepam	117	6.2	6.2
Hydromorphone Hydrochloride	68	6.2	6.2
Albuterol Sulfate	207	6.1	6.1
Glyburide	18	6.1	6.1
Progesterone	17	6.1	6.1
Esomeprazole Magnesium	164	6.1	6.1
Fesoterodine Fumarate	8	6.1	6.1
Escitalopram	100	6.0	6.0
Ibuprofen And Diphenhydramine Citrate	17	6.0	6.0
Clonidine	37	6.0	6.0
Botulinum Toxin Type A	9	6.0	6.0
Metoprolol	174	6.0	6.0
Daspone	7	5.9	5.9
Dapsone Gel, 5%	7	5.9	5.9
Abatacept	95	5.8	5.8
Doxycycline Hyclate	47	5.8	5.8
Metoclopramide	38	5.8	5.8
Doxycycline	47	5.7	5.7
Metoprolol Tartrate	175	5.6	5.6
Indapamide	12	5.5	5.5
Gabapentin	226	5.5	5.5
Anakinra	11	5.5	5.5
Piperacillin Sodium And Tazobactam Sodium	13	5.5	5.5
Timolol	8	5.4	5.4
Dapsone	7	5.4	5.4
Zoledronic Acid	26	5.4	5.4
Montelukast	53	5.3	5.3
Tizanidine	15	5.2	5.2
Travoprost	5	4.7	4.8
Sildenafil	33	4.7	4.7
Conjugated Estrogens	33	4.7	4.7
Estrogens, Conjugated	33	4.6	4.6
Estradiol	47	4.5	4.5
Ranitidine	105	4.5	4.5
Denosumab	106	4.4	4.4
Insulin Lispro	73	4.4	4.4
Tofacitinib Citrate	7	4.4	4.4
Apixaban	35	4.3	4.3
Oxycodone	95	4.3	4.3
Tiotropium Bromide	70	4.3	4.3
Dorzolamide Hydrochloride And Timolol Maleate	4	4.2	4.2
Brimonidine Tartrate	9	4.2	4.2
Etonogestrel And Ethinyl Estradiol	11	4.1	4.1
Nintedanib	15	3.9	3.9
Oxybutynin	14	3.9	3.9
Fluticasone Furoate And Vilanterol Trifenatate	17	3.9	3.9
Dolutegravir Sodium	4	3.6	3.6
Methylphenidate	12	3.4	3.4
Naproxen Sodium Tablet	18	2.8	2.8
Medroxyprogesterone Acetate	16	2.6	2.6
Bimatoprost	9	2.6	2.6
Buprenorphine	28	2.5	2.5
Salicylic Acid	4	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.