OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Methotrexate

1,255 flagged reaction(s) · 2,216,110 total co-reports · max PRR 320.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Human Antichimeric Antibody Positive 291 320.5 320.8 signal
2 Anti-cyclic Citrullinated Peptide Antibody Positive 5,824 237.0 240.3 signal
3 Rheumatoid Factor Positive 4,503 183.1 185.1 signal
4 Swollen Joint Count Increased 2,402 172.0 172.9 signal
5 Anti-cyclic Citrullinated Peptide Antibody 511 167.3 167.5 signal
6 Rheumatic Fever 3,138 129.5 130.5 signal
7 Pemphigus 8,927 129.4 132.2 signal
8 Red Blood Cell Sedimentation Rate Abnormal 1,653 124.4 124.9 signal
9 Lupus Vulgaris 812 108.4 108.6 signal
10 Synovitis 12,276 107.5 110.7 signal
11 Deep Vein Thrombosis Postoperative 1,314 102.4 102.7 signal
12 C-reactive Protein Abnormal 4,291 102.3 103.3 signal
13 Duodenal Ulcer Perforation 4,847 97.9 99.1 signal
14 C-reactive Protein 587 92.1 92.2 signal
15 Hand Deformity 8,415 90.7 92.5 signal
16 Granuloma Skin 497 75.0 75.1 signal
17 Facet Joint Syndrome 1,856 71.6 71.9 signal
18 Rheumatoid Nodule 1,542 61.9 62.1 signal
19 X-ray Abnormal 954 57.2 57.4 signal
20 Bone Erosion 1,850 54.4 54.7 signal
21 Adjustment Disorder With Depressed Mood 1,044 53.5 53.6 signal
22 Dislocation Of Vertebra 1,127 51.1 51.2 signal
23 Muscle Injury 4,115 50.0 50.5 signal
24 Body Height Below Normal 326 50.0 50.0 signal
25 Helicobacter Infection 5,030 48.4 49.0 signal
26 Sleep Disorder Due To General Medical Condition, Insomnia Type 3,056 44.9 45.2 signal
27 Seronegative Arthritis 523 43.3 43.4 signal
28 Folliculitis 4,788 42.9 43.4 signal
29 Retinitis 739 39.4 39.5 signal
30 Contraindicated Product Administered 13,196 38.6 39.8 signal
31 Enthesopathy 684 38.0 38.0 signal
32 Rheumatoid Lung 407 36.3 36.3 signal
33 Dactylitis 404 34.7 34.7 signal
34 Pericarditis 6,527 31.9 32.4 signal
35 Peripheral Venous Disease 1,553 31.5 31.6 signal
36 Blood Pressure Diastolic Abnormal 979 30.5 30.5 signal
37 Blood Parathyroid Hormone Decreased 562 29.9 30.0 signal
38 Joint Destruction 589 29.9 29.9 signal
39 Blood Pressure Systolic Abnormal 932 29.6 29.7 signal
40 Glossodynia 8,347 29.5 30.1 signal
41 Lymphoproliferative Disorder 1,070 28.3 28.4 signal
42 Drug Tolerance Decreased 1,004 27.6 27.7 signal
43 Juvenile Idiopathic Arthritis 862 26.8 26.9 signal
44 Tenosynovitis 963 26.4 26.5 signal
45 Drug Clearance Decreased 435 26.1 26.1 signal
46 Red Blood Cell Sedimentation Rate Increased 3,826 26.0 26.3 signal
47 Rheumatoid Arthritis 38,633 25.7 28.2 signal
48 Acute Graft Versus Host Disease 1,505 23.9 24.0 signal
49 Chronic Graft Versus Host Disease 1,168 23.4 23.4 signal
50 Hypofibrinogenaemia 311 23.3 23.3 signal
51 Blood Iron Abnormal 308 22.6 22.6 signal
52 Epstein-barr Virus Associated Lymphoproliferative Disorder 552 22.4 22.4 signal
53 Grip Strength Decreased 2,718 22.3 22.4 signal
54 Systemic Lupus Erythematosus 10,740 21.5 22.1 signal
55 Panniculitis 729 21.4 21.4 signal
56 Arthrodesis 307 21.3 21.4 signal
57 Acute Graft Versus Host Disease In Skin 826 21.1 21.1 signal
58 Joint Range Of Motion Decreased 3,926 20.5 20.7 signal
59 Acute Graft Versus Host Disease In Intestine 400 19.7 19.7 signal
60 Finger Deformity 1,379 19.6 19.7 signal
61 Wound 7,872 19.5 19.9 signal
62 Histoplasmosis Disseminated 401 17.1 17.1 signal
63 Psoriatic Arthropathy 10,070 16.5 16.9 signal
64 Epstein-barr Virus Infection Reactivation 316 16.4 16.4 signal
65 Central Nervous System Lymphoma 341 16.3 16.3 signal
66 Arthropathy 13,424 15.6 16.1 signal
67 Bursitis 2,799 14.9 15.0 signal
68 Breast Cancer Stage Iii 1,479 14.7 14.8 signal
69 Graft Versus Host Disease In Gastrointestinal Tract 489 14.7 14.7 signal
70 Irritable Bowel Syndrome 4,902 14.7 14.8 signal
71 Therapeutic Product Effect Decreased 10,082 14.5 14.8 signal
72 Foot Deformity 2,516 14.5 14.5 signal
73 Onychomadesis 932 14.3 14.3 signal
74 Polyarthritis 1,159 14.0 14.0 signal
75 Leukoencephalopathy 808 13.6 13.6 signal
76 Fibromyalgia 5,234 13.5 13.7 signal
77 Drug Specific Antibody 293 13.5 13.5 signal
78 Wound Infection 2,307 13.3 13.3 signal
79 Onychomycosis 923 13.2 13.2 signal
80 Febrile Bone Marrow Aplasia 879 13.1 13.1 signal
81 Myelopathy 399 13.1 13.1 signal
82 Lip Dry 1,871 13.0 13.1 signal
83 Graft Versus Host Disease In Skin 456 12.9 12.9 signal
84 Drug Intolerance 19,912 12.9 13.4 signal
85 Hypercholesterolaemia 1,955 12.7 12.7 signal
86 Joint Arthroplasty 358 12.3 12.3 signal
87 Sacroiliitis 371 12.0 12.0 signal
88 C-reactive Protein Increased 7,099 12.0 12.1 signal
89 Impaired Healing 6,323 11.7 11.9 signal
90 Joint Effusion 1,318 11.6 11.6 signal
91 Pseudomonal Sepsis 334 11.5 11.5 signal
92 Joint Swelling 22,670 11.4 12.0 signal
93 Scleritis 298 11.3 11.3 signal
94 Cytomegalovirus Chorioretinitis 354 11.1 11.1 signal
95 Venoocclusive Liver Disease 896 11.0 11.0 signal
96 Synovial Cyst 844 10.9 11.0 signal
97 Pulmonary Fibrosis 3,464 10.9 11.0 signal
98 Antibody Test Positive 303 10.8 10.8 signal
99 Treatment Failure 14,741 10.8 11.1 signal
100 Tuberculin Test Positive 460 10.8 10.8 signal
101 Osteoarthritis 7,602 10.7 10.9 signal
102 Graft Versus Host Disease 1,291 10.7 10.7 signal
103 Pustular Psoriasis 615 10.7 10.7 signal
104 Limb Deformity 282 10.6 10.6 signal
105 Acute Lymphocytic Leukaemia Recurrent 449 10.4 10.4 signal
106 Human Herpesvirus 6 Infection 325 10.1 10.1 signal
107 Arthritis Bacterial 695 10.1 10.1 signal
108 Leukaemia Recurrent 285 10.0 10.0 signal
109 Lower Respiratory Tract Infection 7,610 9.9 10.1 signal
110 Exostosis 1,495 9.6 9.7 signal
111 Autoimmune Disorder 1,549 9.5 9.5 signal
112 Hepatic Enzyme Increased 10,892 9.4 9.6 signal
113 Disseminated Tuberculosis 405 9.3 9.3 signal
114 Infusion Related Reaction 10,505 9.3 9.5 signal
115 Live Birth 1,320 9.3 9.3 signal
116 Epstein-barr Virus Infection 983 9.2 9.3 signal
117 Mucosal Inflammation 4,100 9.2 9.3 signal
118 Alanine Aminotransferase Abnormal 327 9.1 9.1 signal
119 Liver Injury 3,751 9.0 9.1 signal
120 Sciatica 2,427 8.9 8.9 signal
121 Blood Pressure Diastolic Decreased 1,132 8.9 8.9 signal
122 Knee Arthroplasty 3,165 8.8 8.9 signal
123 Nail Disorder 1,318 8.8 8.8 signal
124 Venoocclusive Disease 380 8.8 8.8 signal
125 Hip Arthroplasty 2,295 8.8 8.8 signal
126 Musculoskeletal Stiffness 13,184 8.7 9.0 signal
127 Latent Tuberculosis 313 8.7 8.7 signal
128 Cystitis Haemorrhagic 602 8.7 8.7 signal
129 Pneumocystis Jiroveci Pneumonia 336 8.6 8.6 signal
130 Adenovirus Infection 426 8.6 8.6 signal
131 Cytomegalovirus Infection Reactivation 631 8.5 8.5 signal
132 Lupus-like Syndrome 1,308 8.3 8.4 signal
133 Blepharospasm 898 8.3 8.3 signal
134 Joint Stiffness 3,795 8.3 8.4 signal
135 Faecal Calprotectin Increased 439 8.1 8.1 signal
136 Histiocytosis Haematophagic 423 8.0 8.0 signal
137 Pulmonary Tuberculosis 599 8.0 8.0 signal
138 Aspergillus Infection 906 8.0 8.0 signal
139 Obesity 2,227 8.0 8.0 signal
140 Diffuse Large B-cell Lymphoma 1,062 8.0 8.0 signal
141 Spinal Stenosis 566 7.9 7.9 signal
142 Inflammation 7,099 7.9 8.0 signal
143 Shoulder Arthroplasty 366 7.9 7.9 signal
144 Hepatic Fibrosis 468 7.8 7.8 signal
145 Blood Pressure Diastolic Increased 634 7.8 7.8 signal
146 Stomatitis 8,271 7.8 7.9 signal
147 Diffuse Large B-cell Lymphoma Recurrent 290 7.7 7.7 signal
148 Swelling 12,563 7.7 7.9 signal
149 Pneumocystis Jirovecii Pneumonia 1,342 7.6 7.7 signal
150 Skin Necrosis 697 7.6 7.6 signal
151 Nodule 1,742 7.6 7.6 signal
152 Cytomegalovirus Viraemia 584 7.6 7.6 signal
153 Liver Function Test Increased 2,839 7.6 7.6 signal
154 Cushingoid 428 7.5 7.5 signal
155 Chondropathy 360 7.5 7.5 signal
156 B-cell Lymphoma 446 7.4 7.4 signal
157 Ankylosing Spondylitis 1,699 7.4 7.4 signal
158 Joint Dislocation 1,357 7.3 7.3 signal
159 Demyelination 531 7.3 7.3 signal
160 Inflammatory Marker Increased 628 7.2 7.2 signal
161 Type 2 Diabetes Mellitus 4,255 7.1 7.2 signal
162 Basal Cell Carcinoma 1,960 7.1 7.1 signal
163 Bk Virus Infection 420 7.1 7.1 signal
164 Fine Motor Skill Dysfunction 359 7.0 7.0 signal
165 Uveitis 1,673 7.0 7.0 signal
166 Infusion Site Reaction 360 7.0 7.0 signal
167 Arthritis Infective 574 7.0 7.0 signal
168 Sarcoidosis 587 6.9 6.9 signal
169 Mouth Ulceration 2,566 6.8 6.9 signal
170 Mycobacterium Tuberculosis Complex Test Positive 287 6.8 6.8 signal
171 Blood Pressure Systolic Increased 2,348 6.7 6.7 signal
172 Spondylitis 429 6.6 6.6 signal
173 Dermatomyositis 297 6.5 6.5 signal
174 Sensitivity To Weather Change 611 6.5 6.5 signal
175 Walking Aid User 770 6.5 6.5 signal
176 Discomfort 7,011 6.4 6.5 signal
177 Antinuclear Antibody Positive 375 6.4 6.4 signal
178 Posterior Reversible Encephalopathy Syndrome 1,093 6.4 6.4 signal
179 Arthritis 8,984 6.3 6.4 signal
180 Pneumonia Viral 363 6.3 6.3 signal
181 Mobility Decreased 8,145 6.3 6.4 signal
182 Injection Site Haematoma 1,664 6.3 6.3 signal
183 Laryngitis 1,219 6.2 6.2 signal
184 Loss Of Personal Independence In Daily Activities 5,302 6.2 6.2 signal
185 Mucormycosis 286 6.1 6.2 signal
186 Tuberculosis 1,425 6.1 6.1 signal
187 Musculoskeletal Pain 5,850 6.1 6.2 signal
188 Blood Culture Positive 332 6.1 6.1 signal
189 Maternal Exposure Timing Unspecified 406 6.0 6.0 signal
190 Blister 6,088 6.0 6.1 signal
191 Foot Operation 533 6.0 6.0 signal
192 Bronchiectasis 716 5.9 5.9 signal
193 Pancytopenia 5,955 5.9 6.0 signal
194 Body Temperature Decreased 1,060 5.9 5.9 signal
195 Sinusitis 10,867 5.8 5.9 signal
196 Blood Pressure Fluctuation 2,542 5.8 5.8 signal
197 Blood Cholesterol Increased 4,906 5.8 5.8 signal
198 Pulmonary Toxicity 734 5.7 5.8 signal
199 Staphylococcal Sepsis 518 5.7 5.7 signal
200 Joint Lock 297 5.7 5.7 signal
201 Immunosuppression 905 5.7 5.7 signal
202 Granuloma 360 5.7 5.7 signal
203 Gait Inability 3,428 5.7 5.7 signal
204 Febrile Neutropenia 6,827 5.7 5.7 signal
205 Back Injury 1,111 5.6 5.6 signal
206 Injection Site Irritation 1,291 5.6 5.6 signal
207 Acute Lymphocytic Leukaemia 289 5.6 5.6 signal
208 Immunodeficiency 1,493 5.5 5.6 signal
209 Hepatic Cirrhosis 1,876 5.5 5.5 signal
210 Haemophagocytic Lymphohistiocytosis 711 5.4 5.4 signal
211 Lower Limb Fracture 1,876 5.4 5.4 signal
212 Bronchopulmonary Aspergillosis 757 5.3 5.4 signal
213 Lung Adenocarcinoma 296 5.3 5.3 signal
214 Crepitations 293 5.3 5.3 signal
215 Pulmonary Mass 1,446 5.3 5.3 signal
216 Apparent Death 355 5.3 5.3 signal
217 Skin Ulcer 2,486 5.2 5.3 signal
218 Infection 13,843 5.2 5.4 signal
219 Hepatotoxicity 2,128 5.2 5.2 signal
220 Night Sweats 3,086 5.2 5.2 signal
221 Haematotoxicity 883 5.2 5.2 signal
222 Anal Fissure 508 5.2 5.2 signal
223 Tenderness 990 5.2 5.2 signal
224 Therapeutic Product Effect Incomplete 6,700 5.1 5.2 signal
225 Iritis 288 5.1 5.1 signal
226 Aphthous Ulcer 714 5.0 5.1 signal
227 Skin Plaque 775 5.0 5.0 signal
228 Herpes Simplex 595 5.0 5.0 signal
229 Hepatic Enzyme Abnormal 457 5.0 5.0 signal
230 Pharyngitis 1,138 4.9 5.0 signal
231 Bacterial Sepsis 297 4.9 4.9 signal
232 Ear Pain 1,755 4.9 4.9 signal
233 Arthralgia 36,920 4.8 5.2 signal
234 Product Label Confusion 518 4.8 4.8 signal
235 Pleurisy 527 4.8 4.8 signal
236 Peripheral Swelling 13,545 4.8 4.9 signal
237 Drug Tolerance 445 4.7 4.7 signal
238 Cytomegalovirus Infection 1,456 4.7 4.7 signal
239 Intentional Product Use Issue 7,692 4.7 4.8 signal
240 Hepatic Steatosis 1,622 4.7 4.7 signal
241 Pyoderma Gangrenosum 310 4.7 4.7 signal
242 Therapy Non-responder 3,837 4.6 4.7 signal
243 Gastrointestinal Disorder 7,596 4.6 4.7 signal
244 Abdominal Discomfort 14,360 4.6 4.8 signal
245 Tonsillitis 447 4.6 4.6 signal
246 Pneumonia Fungal 330 4.6 4.6 signal
247 Coeliac Disease 834 4.6 4.6 signal
248 Gastrointestinal Toxicity 400 4.6 4.6 signal
249 Cytopenia 1,009 4.5 4.5 signal
250 Lung Disorder 4,113 4.5 4.5 signal
251 Spinal Fusion Surgery 337 4.5 4.5 signal
252 Viral Upper Respiratory Tract Infection 400 4.5 4.5 signal
253 Staphylococcal Bacteraemia 361 4.5 4.5 signal
254 Erythema Nodosum 291 4.5 4.5 signal
255 Prescribed Overdose 1,603 4.4 4.5 signal
256 Wheelchair User 370 4.4 4.4 signal
257 Drug Specific Antibody Present 536 4.4 4.4 signal
258 Bone Marrow Failure 1,688 4.4 4.4 signal
259 Ill-defined Disorder 5,012 4.4 4.5 signal
260 Thrombotic Microangiopathy 794 4.4 4.4 signal
261 Liver Disorder 3,612 4.4 4.4 signal
262 Hypertriglyceridaemia 475 4.4 4.4 signal
263 Chronic Sinusitis 305 4.4 4.4 signal
264 Diverticulitis 2,246 4.3 4.4 signal
265 Spinal Osteoarthritis 716 4.3 4.3 signal
266 Psoriasis 10,596 4.3 4.4 signal
267 Rhinovirus Infection 307 4.3 4.3 signal
268 Post Transplant Lymphoproliferative Disorder 404 4.3 4.3 signal
269 Ulcer Haemorrhage 544 4.3 4.3 signal
270 Neurotoxicity 1,396 4.3 4.3 signal
271 Immobile 348 4.3 4.3 signal
272 Deformity 749 4.3 4.3 signal
273 Osteoporosis 3,276 4.2 4.3 signal
274 Sinus Congestion 1,076 4.2 4.3 signal
275 Abscess Limb 339 4.2 4.2 signal
276 Postoperative Wound Infection 535 4.2 4.2 signal
277 Anal Abscess 426 4.2 4.2 signal
278 Ear Infection 2,105 4.2 4.3 signal
279 Lymphoma 1,226 4.2 4.2 signal
280 Ulcer 1,259 4.2 4.2 signal
281 Herpes Zoster 4,534 4.2 4.2 signal
282 Tooth Abscess 804 4.2 4.2 signal
283 Nasopharyngitis 14,471 4.2 4.3 signal
284 Intervertebral Disc Degeneration 728 4.2 4.2 signal
285 Tooth Infection 1,028 4.2 4.2 signal
286 Meniscus Injury 476 4.1 4.1 signal
287 Oesophageal Candidiasis 304 4.1 4.1 signal
288 Skin Papilloma 308 4.1 4.1 signal
289 Anal Fistula 408 4.1 4.1 signal
290 Rash Vesicular 368 4.1 4.1 signal
291 Oral Herpes 1,485 4.1 4.1 signal
292 Alopecia 14,991 4.1 4.2 signal
293 Neutropenic Sepsis 545 4.1 4.1 signal
294 Localised Infection 1,829 4.0 4.0 signal
295 Maternal Exposure During Pregnancy 6,642 4.0 4.1 signal
296 Adverse Reaction 999 4.0 4.0 signal
297 Poor Venous Access 773 4.0 4.0 signal
298 Fear Of Injection 520 4.0 4.0 signal
299 Respiratory Tract Congestion 1,181 3.9 4.0 signal
300 Lung Neoplasm 319 3.9 3.9 signal
301 Joint Injury 1,579 3.9 3.9 signal
302 Musculoskeletal Disorder 1,412 3.9 3.9 signal
303 Hypogammaglobulinaemia 470 3.9 3.9 signal
304 Hypercalcaemia 904 3.9 3.9 signal
305 Hepatitis 1,874 3.9 3.9 signal
306 Spinal Pain 855 3.9 3.9 signal
307 Tibia Fracture 343 3.9 3.9 signal
308 Post Procedural Infection 590 3.9 3.9 signal
309 Red Cell Distribution Width Increased 302 3.8 3.9 signal
310 Carpal Tunnel Syndrome 1,016 3.8 3.8 signal
311 Encephalitis 499 3.8 3.8 signal
312 Muscle Spasticity 896 3.8 3.8 signal
313 Squamous Cell Carcinoma 678 3.8 3.8 signal
314 Subcutaneous Abscess 345 3.8 3.8 signal
315 Septic Shock 3,107 3.8 3.8 signal
316 Drug Level Below Therapeutic 394 3.8 3.8 signal
317 Escherichia Urinary Tract Infection 304 3.8 3.8 signal
318 Enterococcal Infection 346 3.8 3.8 signal
319 Injection Site Warmth 1,461 3.8 3.8 signal
320 Adrenal Insufficiency 849 3.8 3.8 signal
321 Hypertransaminasaemia 482 3.7 3.7 signal
322 Rhinitis 570 3.7 3.7 signal
323 Drug Eruption 1,244 3.7 3.7 signal
324 Organising Pneumonia 346 3.7 3.7 signal
325 Cyst 875 3.7 3.7 signal
326 Body Temperature Increased 1,434 3.7 3.7 signal
327 Bacterial Infection 1,300 3.7 3.7 signal
328 Trigger Finger 284 3.7 3.7 signal
329 Neck Pain 3,915 3.7 3.7 signal
330 Hyperbilirubinaemia 717 3.7 3.7 signal
331 Drug Effect Incomplete 2,564 3.7 3.7 signal
332 Disability 1,375 3.7 3.7 signal
333 Skin Lesion 1,890 3.7 3.7 signal
334 Vasculitis 809 3.7 3.7 signal
335 Upper Respiratory Tract Infection 3,202 3.7 3.7 signal
336 Injection Site Papule 313 3.7 3.7 signal
337 Klebsiella Infection 347 3.6 3.6 signal
338 Myelodysplastic Syndrome 991 3.6 3.6 signal
339 Rotator Cuff Syndrome 879 3.6 3.6 signal
340 Prescribed Underdose 1,360 3.6 3.6 signal
341 Interstitial Lung Disease 3,262 3.6 3.6 signal
342 Abscess 1,072 3.5 3.5 signal
343 Skin Infection 748 3.5 3.5 signal
344 Clostridium Difficile Colitis 710 3.5 3.5 signal
345 Bronchitis 4,971 3.5 3.5 signal
346 Condition Aggravated 20,123 3.5 3.6 signal
347 Hypoalbuminaemia 506 3.5 3.5 signal
348 Hypersensitivity 12,222 3.5 3.5 signal
349 General Physical Health Deterioration 7,566 3.5 3.5 signal
350 Herpes Virus Infection 379 3.5 3.5 signal
351 Pseudomonas Infection 554 3.4 3.4 signal
352 Progressive Multifocal Leukoencephalopathy 540 3.4 3.4 signal
353 Drug Hypersensitivity 12,619 3.4 3.5 signal
354 Sleep Disorder 4,539 3.4 3.4 signal
355 Heart Rate Decreased 2,270 3.4 3.4 signal
356 Breast Cancer Stage Ii 537 3.4 3.4 signal
357 Iron Deficiency 282 3.3 3.3 signal
358 Streptococcal Infection 353 3.3 3.3 signal
359 Therapy Partial Responder 953 3.3 3.3 signal
360 Vaginal Infection 298 3.3 3.3 signal
361 Malignant Melanoma 847 3.3 3.3 signal
362 Contusion 6,064 3.3 3.3 signal
363 Drug-induced Liver Injury 1,937 3.3 3.3 signal
364 Intervertebral Disc Protrusion 1,369 3.3 3.3 signal
365 Bacteraemia 735 3.3 3.3 signal
366 Osteomyelitis 1,129 3.3 3.3 signal
367 Myositis 559 3.3 3.3 signal
368 Injection Site Reaction 4,268 3.3 3.3 signal
369 Tendon Disorder 405 3.3 3.3 signal
370 Pharyngolaryngeal Pain 334 3.2 3.3 signal
371 Pain In Extremity 18,174 3.2 3.3 signal
372 Respiratory Disorder 1,844 3.2 3.2 signal
373 Limb Operation 292 3.2 3.2 signal
374 Oral Disorder 450 3.2 3.2 signal
375 Aplastic Anaemia 321 3.2 3.2 signal
376 Staphylococcal Infection 2,024 3.2 3.2 signal
377 Enteritis 387 3.2 3.2 signal
378 Wheezing 3,600 3.2 3.2 signal
379 Candida Infection 1,013 3.2 3.2 signal
380 Therapeutic Response Decreased 3,659 3.2 3.2 signal
381 Leukopenia 3,020 3.2 3.2 signal
382 Nephropathy Toxic 674 3.2 3.2 signal
383 Hyperkeratosis 334 3.2 3.2 signal
384 Cellulitis 3,042 3.2 3.2 signal
385 Stress Fracture 327 3.1 3.1 signal
386 Local Swelling 1,063 3.1 3.1 signal
387 Erysipelas 303 3.1 3.1 signal
388 Gastrointestinal Infection 535 3.1 3.1 signal
389 Spinal Disorder 565 3.1 3.1 signal
390 Spinal Column Stenosis 285 3.1 3.1 signal
391 Liver Function Test Abnormal 1,741 3.1 3.1 signal
392 Cystitis 1,895 3.1 3.1 signal
393 Respiratory Tract Infection 1,538 3.1 3.1 signal
394 Acute Myeloid Leukaemia 915 3.1 3.1 signal
395 Tendonitis 911 3.1 3.1 signal
396 Acute Respiratory Distress Syndrome 1,036 3.1 3.1 signal
397 Pain 36,017 3.1 3.3 signal
398 Arthropod Bite 430 3.1 3.1 signal
399 Oedema 3,166 3.1 3.1 signal
400 Pyelonephritis 499 3.0 3.0 signal
401 Pharyngitis Streptococcal 626 3.0 3.0 signal
402 Osteopenia 882 3.0 3.0 signal
403 Drug Ineffective 75,965 3.0 3.5 signal
404 Lung Infiltration 513 3.0 3.0 signal
405 Foot Fracture 1,094 3.0 3.0 signal
406 Injection Site Pruritus 3,822 3.0 3.0 signal
407 Transaminases Increased 1,275 3.0 3.0 signal
408 Immune System Disorder 755 3.0 3.0 signal
409 Road Traffic Accident 2,394 3.0 3.0 signal
410 Gastrointestinal Inflammation 445 3.0 3.0 signal
411 Incorrect Route Of Product Administration 961 3.0 3.0 signal
412 Skin Laceration 617 3.0 3.0 signal
413 Oral Candidiasis 743 3.0 3.0 signal
414 Escherichia Infection 467 3.0 3.0 signal
415 Dyslipidaemia 286 2.9 2.9 signal
416 Sepsis 6,273 2.9 3.0 signal
417 Fistula 627 2.9 2.9 signal
418 Meningitis 371 2.9 2.9 signal
419 Pneumonia Bacterial 503 2.9 2.9 signal
420 Nerve Compression 507 2.9 2.9 signal
421 Squamous Cell Carcinoma Of Skin 330 2.9 2.9 signal
422 Drug Effect Decreased 2,983 2.8 2.9 signal
423 Tendon Rupture 670 2.8 2.8 signal
424 Kidney Infection 1,058 2.8 2.8 signal
425 Musculoskeletal Discomfort 925 2.8 2.8 signal
426 Impaired Work Ability 1,153 2.8 2.8 signal
427 Cataract 3,188 2.8 2.8 signal
428 Diverticulum 387 2.8 2.8 signal
429 Tongue Disorder 391 2.8 2.8 signal
430 Dermatitis Allergic 666 2.8 2.8 signal
431 Pneumonitis 1,444 2.8 2.8 signal
432 Viral Infection 1,775 2.8 2.8 signal
433 Gastroenteritis 778 2.8 2.8 signal
434 Sensory Loss 431 2.8 2.8 signal
435 Fungal Infection 1,767 2.8 2.8 signal
436 Tooth Fracture 585 2.8 2.8 signal
437 Congenital Anomaly 410 2.7 2.7 signal
438 Alanine Aminotransferase Increased 3,219 2.7 2.7 signal
439 Furuncle 413 2.7 2.7 signal
440 Frequent Bowel Movements 1,401 2.7 2.7 signal
441 Lung Infection 818 2.7 2.7 signal
442 Atelectasis 503 2.7 2.7 signal
443 Skin Mass 344 2.7 2.7 signal
444 Multiple Organ Dysfunction Syndrome 1,444 2.7 2.7 signal
445 Injury 3,655 2.7 2.7 signal
446 Hemiparesis 880 2.7 2.7 signal
447 Hypertension 10,939 2.7 2.7 signal
448 Mass 719 2.7 2.7 signal
449 Tumour Lysis Syndrome 448 2.7 2.7 signal
450 Pneumonia 16,550 2.7 2.7 signal
451 Sputum Discoloured 481 2.6 2.6 signal
452 Vitamin D Decreased 435 2.6 2.6 signal
453 Injection Site Erythema 6,254 2.6 2.6 signal
454 Weight Increased 11,226 2.6 2.7 signal
455 Lymphadenopathy 1,783 2.6 2.6 signal
456 Oropharyngeal Pain 4,652 2.6 2.6 signal
457 Pyrexia 17,378 2.6 2.7 signal
458 Hepatomegaly 495 2.6 2.6 signal
459 Product Use Issue 9,368 2.6 2.6 signal
460 Bone Disorder 916 2.6 2.6 signal
461 Odynophagia 294 2.6 2.6 signal
462 Spinal Compression Fracture 417 2.6 2.6 signal
463 Breast Mass 333 2.6 2.6 signal
464 Skin Atrophy 282 2.5 2.5 signal
465 Renal Cyst 389 2.5 2.5 signal
466 Covid-19 Pneumonia 581 2.5 2.5 signal
467 Ligament Sprain 480 2.5 2.5 signal
468 Secretion Discharge 599 2.5 2.5 signal
469 Pulmonary Haemorrhage 379 2.5 2.5 signal
470 Urosepsis 446 2.5 2.5 signal
471 Lymphopenia 678 2.5 2.5 signal
472 Pelvic Fracture 371 2.5 2.5 signal
473 Eye Infection 535 2.5 2.5 signal
474 Drug Level Decreased 487 2.5 2.5 signal
475 Arterial Occlusive Disease 376 2.5 2.5 signal
476 Influenza 5,309 2.4 2.5 signal
477 Injection Site Induration 615 2.4 2.4 signal
478 Emphysema 480 2.4 2.4 signal
479 Papule 329 2.4 2.4 signal
480 Injection Site Swelling 3,571 2.4 2.4 signal
481 Increased Tendency To Bruise 432 2.4 2.4 signal
482 Rash 20,259 2.4 2.5 signal
483 Hypoaesthesia 6,998 2.4 2.4 signal
484 Disseminated Intravascular Coagulation 659 2.4 2.4 signal
485 Injection Site Pain 14,128 2.4 2.4 signal
486 Motor Dysfunction 469 2.4 2.4 signal
487 Decreased Immune Responsiveness 453 2.4 2.4 signal
488 Rhinorrhoea 2,987 2.4 2.4 signal
489 Respiratory Rate Increased 411 2.4 2.4 signal
490 Rash Pustular 338 2.4 2.4 signal
491 Gingival Pain 367 2.4 2.4 signal
492 Diarrhoea Haemorrhagic 429 2.4 2.4 signal
493 Tooth Disorder 1,023 2.4 2.4 signal
494 Hemiplegia 382 2.4 2.4 signal
495 Device Related Infection 706 2.4 2.4 signal
496 Glaucoma 881 2.4 2.4 signal
497 Hand Fracture 324 2.4 2.4 signal
498 Productive Cough 2,163 2.4 2.4 signal
499 Injection Site Bruising 3,599 2.4 2.4 signal
500 Knee Operation 443 2.3 2.4 signal
501 Weight Fluctuation 473 2.3 2.3 signal
502 Maternal Exposure Before Pregnancy 307 2.3 2.3 signal
503 Drug Ineffective For Unapproved Indication 2,518 2.3 2.3 signal
504 Gait Disturbance 8,651 2.3 2.3 signal
505 Taste Disorder 901 2.3 2.3 signal
506 Nephrolithiasis 2,055 2.3 2.3 signal
507 Dysstasia 1,316 2.3 2.3 signal
508 Photosensitivity Reaction 735 2.3 2.3 signal
509 Limb Injury 1,207 2.3 2.3 signal
510 Facial Paralysis 378 2.3 2.3 signal
511 Colitis 1,676 2.3 2.3 signal
512 Oral Pain 998 2.3 2.3 signal
513 Encephalopathy 1,088 2.3 2.3 signal
514 Hiatus Hernia 576 2.3 2.3 signal
515 Hepatocellular Injury 630 2.3 2.3 signal
516 Limb Discomfort 1,366 2.3 2.3 signal
517 Gastroenteritis Viral 797 2.3 2.3 signal
518 Iron Deficiency Anaemia 404 2.3 2.3 signal
519 Gastrointestinal Pain 480 2.3 2.3 signal
520 Polyp 287 2.3 2.3 signal
521 Multi-organ Failure 768 2.2 2.3 signal
522 Delirium 1,512 2.2 2.3 signal
523 Ankle Fracture 677 2.2 2.2 signal
524 Back Disorder 713 2.2 2.2 signal
525 Groin Pain 384 2.2 2.2 signal
526 Thrombocytopenia 4,844 2.2 2.2 signal
527 Skin Haemorrhage 624 2.2 2.2 signal
528 Oxygen Saturation Decreased 2,405 2.2 2.2 signal
529 Aspartate Aminotransferase Increased 2,288 2.2 2.2 signal
530 Clostridium Difficile Infection 933 2.2 2.2 signal
531 Cardiotoxicity 381 2.2 2.2 signal
532 Epilepsy 1,310 2.2 2.2 signal
533 Blood Iron Decreased 506 2.2 2.2 signal
534 Mouth Haemorrhage 312 2.2 2.2 signal
535 Uterine Leiomyoma 312 2.2 2.2 signal
536 Myelosuppression 1,446 2.2 2.2 signal
537 Urticaria 7,066 2.2 2.2 signal
538 Pulmonary Thrombosis 463 2.2 2.2 signal
539 Cardiac Murmur 368 2.2 2.2 signal
540 Injection Site Discolouration 522 2.2 2.2 signal
541 Polyneuropathy 500 2.2 2.2 signal
542 Gastric Ulcer 797 2.1 2.1 signal
543 Injection Site Rash 1,266 2.1 2.1 signal
544 Dry Mouth 3,366 2.1 2.1 signal
545 Neutropenia 5,621 2.1 2.1 signal
546 Blood Test Abnormal 579 2.1 2.1 signal
547 Ovarian Cyst 413 2.1 2.1 signal
548 Migraine 3,894 2.1 2.1 signal
549 Pregnancy 830 2.1 2.1 signal
550 Dyspepsia 4,022 2.1 2.1 signal
551 Product Use In Unapproved Indication 10,008 2.1 2.1 signal
552 Muscular Weakness 4,629 2.1 2.1 signal
553 Exposure During Pregnancy 2,532 2.1 2.1 signal
554 Colitis Ulcerative 1,813 2.1 2.1 signal
555 Skin Cancer 868 2.1 2.1 signal
556 Confusional State 6,520 2.1 2.1 signal
557 Dental Caries 444 2.1 2.1 signal
558 Off Label Use 34,769 2.1 2.1 signal
559 Nasal Congestion 2,341 2.0 2.1 signal
560 Scab 453 2.0 2.0 signal
561 Skin Reaction 562 2.0 2.0 signal
562 Vitamin D Deficiency 389 2.0 2.0 signal
563 Therapeutic Response Shortened 1,270 2.0 2.0 signal
564 Gastric Disorder 1,389 2.0 2.0 signal
565 Adverse Drug Reaction 3,568 2.0 2.1 signal
566 Back Pain 9,218 2.0 2.1 signal
567 Eye Inflammation 374 2.0 2.0 signal
568 Blood Lactate Dehydrogenase Increased 631 2.0 2.0 signal
569 Oedema Peripheral 4,825 2.0 2.0 signal
570 Respiratory Failure 2,869 2.0 2.0 signal
571 Skin Disorder 1,306 2.0 2.0 signal
572 Toothache 710 2.0 2.0 signal
573 Pleural Effusion 2,387 2.0 2.0 signal
574 Coagulopathy 651 2.0 2.0 signal
575 Pneumothorax 620 2.0 2.0 signal
576 Sinus Disorder 775 2.0 2.0 no signal
577 Musculoskeletal Chest Pain 604 2.0 2.0 no signal
578 Injection Site Urticaria 944 2.0 2.0 no signal
579 Urinary Tract Infection 6,610 2.0 2.0 no signal
580 Injection Site Extravasation 485 2.0 2.0 no signal
581 Blood Albumin Decreased 305 2.0 2.0 no signal
582 Nerve Injury 430 2.0 2.0 no signal
583 Pulmonary Congestion 510 2.0 2.0 no signal
584 Rash Pruritic 2,065 2.0 2.0 no signal
585 Hepatic Cytolysis 467 2.0 2.0 no signal
586 Cough 10,685 2.0 2.0 no signal
587 Fatigue 29,644 1.9 2.0 no signal
588 Stress 2,737 1.9 2.0 no signal
589 Femur Fracture 1,181 1.9 1.9 no signal
590 Splenomegaly 445 1.9 1.9 no signal
591 Appendicitis 349 1.9 1.9 no signal
592 Disease Recurrence 1,790 1.9 1.9 no signal
593 Blood Pressure Increased 5,742 1.9 1.9 no signal
594 Aortic Aneurysm 287 1.9 1.9 no signal
595 Wrist Fracture 449 1.9 1.9 no signal
596 Platelet Count Increased 488 1.9 1.9 no signal
597 Gastritis 981 1.9 1.9 no signal
598 Intestinal Perforation 419 1.9 1.9 no signal
599 Muscle Strain 321 1.9 1.9 no signal
600 Drug Level Increased 614 1.9 1.9 no signal
601 Post Procedural Complication 713 1.9 1.9 no signal
602 Bedridden 485 1.9 1.9 no signal
603 Hepatic Function Abnormal 1,369 1.9 1.9 no signal
604 Hernia 708 1.9 1.9 no signal
605 Upper Limb Fracture 736 1.9 1.9 no signal
606 Weight Decreased 10,231 1.9 1.9 no signal
607 Myopathy 316 1.9 1.9 no signal
608 Impaired Quality Of Life 523 1.9 1.9 no signal
609 Haematochezia 1,995 1.8 1.8 no signal
610 Laceration 345 1.8 1.8 no signal
611 Hidradenitis 314 1.8 1.8 no signal
612 Anaphylactic Reaction 1,978 1.8 1.8 no signal
613 Abdominal Pain 8,362 1.8 1.9 no signal
614 Small Intestinal Obstruction 441 1.8 1.8 no signal
615 Abdominal Pain Upper 7,308 1.8 1.8 no signal
616 Injection Site Haemorrhage 2,817 1.8 1.8 no signal
617 Drug Resistance 909 1.8 1.8 no signal
618 Malaise 15,520 1.8 1.8 no signal
619 Neuralgia 848 1.8 1.8 no signal
620 White Blood Cell Count Increased 1,345 1.8 1.8 no signal
621 Pericardial Effusion 803 1.8 1.8 no signal
622 Rectal Haemorrhage 1,504 1.8 1.8 no signal
623 Eye Disorder 1,143 1.8 1.8 no signal
624 Cholelithiasis 1,140 1.8 1.8 no signal
625 Gastrooesophageal Reflux Disease 2,774 1.8 1.8 no signal
626 Rib Fracture 708 1.8 1.8 no signal
627 Scratch 357 1.8 1.8 no signal
628 Pancreatitis 1,819 1.7 1.8 no signal
629 Tooth Extraction 427 1.7 1.7 no signal
630 Second Primary Malignancy 285 1.7 1.7 no signal
631 Hypophagia 868 1.7 1.7 no signal
632 Movement Disorder 1,102 1.7 1.7 no signal
633 Pain In Jaw 968 1.7 1.7 no signal
634 Conjunctivitis 627 1.7 1.7 no signal
635 Diabetes Mellitus 2,607 1.7 1.7 no signal
636 Headache 21,283 1.7 1.8 no signal
637 Agranulocytosis 624 1.7 1.7 no signal
638 Fracture 639 1.7 1.7 no signal
639 Respiratory Syncytial Virus Infection 292 1.7 1.7 no signal
640 Thyroid Disorder 516 1.7 1.7 no signal
641 Asthma 3,747 1.7 1.7 no signal
642 Affect Lability 323 1.7 1.7 no signal
643 Cholecystitis 396 1.7 1.7 no signal
644 Sneezing 745 1.7 1.7 no signal
645 Hysterectomy 286 1.7 1.7 no signal
646 Vomiting 15,424 1.7 1.7 no signal
647 Medication Error 1,811 1.7 1.7 no signal
648 Inflammatory Bowel Disease 321 1.7 1.7 no signal
649 Adverse Event 2,999 1.7 1.7 no signal
650 Heart Rate Irregular 739 1.7 1.7 no signal
651 Deafness 851 1.6 1.7 no signal
652 Spinal Fracture 646 1.6 1.6 no signal
653 Spinal Operation 391 1.6 1.6 no signal
654 Dry Eye 1,562 1.6 1.6 no signal
655 Brain Oedema 406 1.6 1.6 no signal
656 Chest Pain 5,946 1.6 1.6 no signal
657 Accident 381 1.6 1.6 no signal
658 Haemorrhoids 625 1.6 1.6 no signal
659 Blood Bilirubin Increased 865 1.6 1.6 no signal
660 Flank Pain 298 1.6 1.6 no signal
661 Quality Of Life Decreased 427 1.6 1.6 no signal
662 Seasonal Allergy 448 1.6 1.6 no signal
663 Coronary Artery Occlusion 436 1.6 1.6 no signal
664 Colon Cancer 472 1.6 1.6 no signal
665 Dermatitis 654 1.6 1.6 no signal
666 Hypertensive Crisis 352 1.6 1.6 no signal
667 Photophobia 588 1.6 1.6 no signal
668 Paraesthesia 4,954 1.6 1.6 no signal
669 Eating Disorder 669 1.6 1.6 no signal
670 Facial Pain 279 1.6 1.6 no signal
671 Acute Respiratory Failure 597 1.6 1.6 no signal
672 Covid-19 5,512 1.6 1.6 no signal
673 Rebound Effect 352 1.6 1.6 no signal
674 Nausea 24,479 1.6 1.6 no signal
675 Cholestasis 592 1.6 1.6 no signal
676 Anaemia 5,909 1.6 1.6 no signal
677 Haematocrit Decreased 618 1.6 1.6 no signal
678 Sleep Apnoea Syndrome 586 1.6 1.6 no signal
679 Ascites 897 1.5 1.5 no signal
680 Amnesia 1,992 1.5 1.5 no signal
681 Angina Pectoris 879 1.5 1.5 no signal
682 Neoplasm 350 1.5 1.5 no signal
683 Deep Vein Thrombosis 1,979 1.5 1.5 no signal
684 Pruritus 11,425 1.5 1.5 no signal
685 Cholecystectomy 343 1.5 1.5 no signal
686 Disease Progression 3,548 1.5 1.5 no signal
687 Oesophagitis 328 1.5 1.5 no signal
688 Osteonecrosis 993 1.5 1.5 no signal
689 Malnutrition 332 1.5 1.5 no signal
690 Aphasia 900 1.5 1.5 no signal
691 Inappropriate Schedule Of Product Administration 5,221 1.5 1.5 no signal
692 Feeling Hot 1,809 1.5 1.5 no signal
693 Influenza Like Illness 2,428 1.5 1.5 no signal
694 Toxic Epidermal Necrolysis 442 1.5 1.5 no signal
695 Gamma-glutamyltransferase Increased 650 1.5 1.5 no signal
696 Respiratory Distress 808 1.5 1.5 no signal
697 Mitral Valve Incompetence 331 1.5 1.5 no signal
698 Petechiae 304 1.5 1.5 no signal
699 Body Height Decreased 315 1.5 1.5 no signal
700 Scar 498 1.5 1.5 no signal
701 Diarrhoea 18,616 1.5 1.5 no signal
702 Hepatic Failure 872 1.5 1.5 no signal
703 Hypokinesia 419 1.5 1.5 no signal
704 Ear Discomfort 295 1.5 1.5 no signal
705 Fall 9,578 1.5 1.5 no signal
706 Renal Impairment 2,406 1.5 1.5 no signal
707 Asthenia 10,745 1.4 1.5 no signal
708 Gallbladder Disorder 510 1.4 1.4 no signal
709 Pulmonary Embolism 2,717 1.4 1.4 no signal
710 Injection Site Nodule 311 1.4 1.4 no signal
711 No Therapeutic Response 350 1.4 1.4 no signal
712 Blood Creatinine Increased 1,846 1.4 1.4 no signal
713 Obstructive Airways Disorder 312 1.4 1.4 no signal
714 Aphonia 389 1.4 1.4 no signal
715 Injection Site Discomfort 287 1.4 1.4 no signal
716 Erythema 5,705 1.4 1.4 no signal
717 Cardiomegaly 344 1.4 1.4 no signal
718 Rash Erythematous 1,295 1.4 1.4 no signal
719 Sars-cov-2 Test Positive 369 1.4 1.4 no signal
720 Drug Toxicity 381 1.4 1.4 no signal
721 Toxicity To Various Agents 4,626 1.4 1.4 no signal
722 Ileus 339 1.4 1.4 no signal
723 Brain Neoplasm 253 1.4 1.4 no signal
724 Gout 493 1.4 1.4 no signal
725 Feeding Disorder 546 1.4 1.4 no signal
726 Rash Papular 613 1.4 1.4 no signal
727 Chills 3,197 1.4 1.4 no signal
728 Hyperlipidaemia 325 1.4 1.4 no signal
729 Retinal Detachment 249 1.4 1.4 no signal
730 Generalised Oedema 333 1.4 1.4 no signal
731 White Blood Cell Count Decreased 2,930 1.4 1.4 no signal
732 Haemoglobin Decreased 2,776 1.4 1.4 no signal
733 Rash Maculo-papular 595 1.4 1.4 no signal
734 Insomnia 7,159 1.4 1.4 no signal
735 Neutrophil Count Decreased 1,085 1.4 1.4 no signal
736 Skin Discolouration 1,230 1.4 1.4 no signal
737 Atrial Fibrillation 2,604 1.3 1.3 no signal
738 Hypoxia 935 1.3 1.3 no signal
739 Memory Impairment 3,662 1.3 1.3 no signal
740 Decreased Appetite 6,160 1.3 1.3 no signal
741 Laboratory Test Abnormal 784 1.3 1.3 no signal
742 Pancreatitis Acute 593 1.3 1.3 no signal
743 Tachycardia 2,355 1.3 1.3 no signal
744 Depression 6,052 1.3 1.3 no signal
745 Throat Irritation 1,179 1.3 1.3 no signal
746 Metastases To Lung 304 1.3 1.3 no signal
747 Neutrophil Count Increased 270 1.3 1.3 no signal
748 Oral Discomfort 364 1.3 1.3 no signal
749 Surgery 1,514 1.3 1.3 no signal
750 Nephropathy 245 1.3 1.3 no signal
751 Dyspnoea 14,731 1.3 1.3 no signal
752 Impaired Gastric Emptying 331 1.3 1.3 no signal
753 Cardiomyopathy 384 1.3 1.3 no signal
754 Dyspnoea Exertional 970 1.3 1.3 no signal
755 Bone Density Decreased 818 1.3 1.3 no signal
756 Poor Quality Sleep 551 1.3 1.3 no signal
757 Acute Hepatic Failure 350 1.3 1.3 no signal
758 Acute Kidney Injury 3,909 1.3 1.3 no signal
759 Nervous System Disorder 801 1.3 1.3 no signal
760 Tachypnoea 346 1.3 1.3 no signal
761 Hypokalaemia 1,164 1.3 1.3 no signal
762 Dry Throat 257 1.3 1.3 no signal
763 Abdominal Distension 2,627 1.3 1.3 no signal
764 Red Blood Cell Count Decreased 720 1.3 1.3 no signal
765 Muscle Spasms 4,596 1.3 1.3 no signal
766 Renal Pain 264 1.3 1.3 no signal
767 Illness 2,510 1.3 1.3 no signal
768 Drug Interaction 3,960 1.3 1.3 no signal
769 Sleep Disorder Due To A General Medical Condition 402 1.3 1.3 no signal
770 Intestinal Obstruction 929 1.2 1.2 no signal
771 Pain Of Skin 666 1.2 1.2 no signal
772 Dysphonia 1,439 1.2 1.2 no signal
773 Chronic Obstructive Pulmonary Disease 1,282 1.2 1.2 no signal
774 Ataxia 293 1.2 1.2 no signal
775 Blood Urine Present 467 1.2 1.2 no signal
776 Heart Rate Increased 2,427 1.2 1.2 no signal
777 Macular Degeneration 291 1.2 1.2 no signal
778 Anorexia 319 1.2 1.2 no signal
779 Lung Neoplasm Malignant 1,007 1.2 1.2 no signal
780 Blindness Unilateral 343 1.2 1.2 no signal
781 Peripheral Coldness 335 1.2 1.2 no signal
782 Procedural Pain 672 1.2 1.2 no signal
783 Electrolyte Imbalance 279 1.2 1.2 no signal
784 Coordination Abnormal 340 1.2 1.2 no signal
785 Pulmonary Oedema 1,078 1.2 1.2 no signal
786 Pharyngeal Oedema 375 1.2 1.2 no signal
787 Abasia 602 1.2 1.2 no signal
788 Hypothyroidism 764 1.2 1.2 no signal
789 Epistaxis 1,794 1.2 1.2 no signal
790 Skin Fissures 450 1.2 1.2 no signal
791 Dysarthria 895 1.2 1.2 no signal
792 Wrong Technique In Drug Usage Process 874 1.2 1.2 no signal
793 Gingival Bleeding 324 1.2 1.2 no signal
794 Renal Failure 3,156 1.2 1.2 no signal
795 Hypocalcaemia 445 1.2 1.2 no signal
796 Renal Tubular Necrosis 231 1.2 1.2 no signal
797 Burning Sensation 1,642 1.2 1.2 no signal
798 Incontinence 248 1.2 1.2 no signal
799 Leukocytosis 422 1.2 1.2 no signal
800 Dysuria 860 1.2 1.2 no signal
801 Ovarian Cancer 216 1.2 1.2 no signal
802 Visual Impairment 2,868 1.2 1.2 no signal
803 Feeling Cold 649 1.2 1.2 no signal
804 Metastases To Liver 407 1.2 1.2 no signal
805 Vertigo 1,414 1.2 1.2 no signal
806 Inappropriate Antidiuretic Hormone Secretion 236 1.2 1.2 no signal
807 Neuropathy Peripheral 2,190 1.2 1.2 no signal
808 Leukaemia 218 1.2 1.2 no signal
809 Lymphocyte Count Decreased 407 1.2 1.2 no signal
810 Device Malfunction 1,543 1.2 1.2 no signal
811 Thrombosis 1,852 1.2 1.2 no signal
812 Renal Disorder 1,067 1.1 1.1 no signal
813 Bladder Disorder 227 1.1 1.1 no signal
814 Neoplasm Malignant 1,518 1.1 1.1 no signal
815 Pallor 620 1.1 1.1 no signal
816 Cytokine Release Syndrome 431 1.1 1.1 no signal
817 Ejection Fraction Decreased 352 1.1 1.1 no signal
818 Supraventricular Tachycardia 216 1.1 1.1 no signal
819 Muscle Atrophy 284 1.1 1.1 no signal
820 Transient Ischaemic Attack 755 1.1 1.1 no signal
821 Chest Discomfort 2,272 1.1 1.1 no signal
822 Grand Mal Convulsion 208 1.1 1.1 no signal
823 Tubulointerstitial Nephritis 415 1.1 1.1 no signal
824 Blood Alkaline Phosphatase Increased 549 1.1 1.1 no signal
825 Activities Of Daily Living Impaired 443 1.1 1.1 no signal
826 Intentional Dose Omission 603 1.1 1.1 no signal
827 Product Prescribing Error 522 1.1 1.1 no signal
828 Myocardial Ischaemia 253 1.1 1.1 no signal
829 Haemoptysis 614 1.1 1.1 no signal
830 Rash Macular 762 1.1 1.1 no signal
831 Haematuria 749 1.1 1.1 no signal
832 Cerebral Infarction 533 1.1 1.1 no signal
833 Abdominal Pain Lower 551 1.1 1.1 no signal
834 Renal Failure Acute 935 1.1 1.1 no signal
835 Pruritus Generalised 476 1.1 1.1 no signal
836 Blood Pressure Abnormal 429 1.1 1.1 no signal
837 Dizziness 10,749 1.1 1.1 no signal
838 Paralysis 310 1.1 1.1 no signal
839 Hip Fracture 692 1.1 1.1 no signal
840 Sinus Tachycardia 305 1.1 1.1 no signal
841 Platelet Count Decreased 2,291 1.1 1.1 no signal
842 Thyroid Cancer 259 1.1 1.1 no signal
843 Coronary Artery Disease 647 1.1 1.1 no signal
844 Haematoma 547 1.1 1.1 no signal
845 Intraocular Pressure Increased 270 1.1 1.1 no signal
846 Mental Status Changes 583 1.1 1.1 no signal
847 Vitreous Floaters 204 1.1 1.1 no signal
848 Shock 477 1.0 1.0 no signal
849 Hypotension 4,175 1.0 1.0 no signal
850 Blood Triglycerides Increased 368 1.0 1.0 no signal
851 Eyelid Ptosis 211 1.0 1.0 no signal
852 Bone Pain 1,216 1.0 1.0 no signal
853 Diplopia 536 1.0 1.0 no signal
854 Accidental Overdose 753 1.0 1.0 no signal
855 Dysphagia 1,948 1.0 1.0 no signal
856 Cardiac Failure 1,651 1.0 1.0 no signal
857 Swelling Face 1,335 1.0 1.0 no signal
858 Pharyngeal Swelling 196 1.0 1.0 no signal
859 Eye Haemorrhage 270 1.0 1.0 no signal
860 Subdural Haematoma 290 1.0 1.0 no signal
861 Subarachnoid Haemorrhage 206 1.0 1.0 no signal
862 Proteinuria 377 1.0 1.0 no signal
863 Blood Pressure Decreased 1,326 1.0 1.0 no signal
864 Swollen Tongue 625 1.0 1.0 no signal
865 Skin Exfoliation 1,660 1.0 1.0 no signal
866 Pulmonary Hypertension 415 1.0 1.0 no signal
867 Acute Myocardial Infarction 587 1.0 1.0 no signal
868 Eosinophilia 345 1.0 1.0 no signal
869 Peritonitis 408 1.0 1.0 no signal
870 Myalgia 3,331 1.0 1.0 no signal
871 Urinary Incontinence 580 1.0 1.0 no signal
872 Sensory Disturbance 315 1.0 1.0 no signal
873 Blood Urea Increased 328 1.0 1.0 no signal
874 Lacrimation Increased 582 1.0 1.0 no signal
875 Fluid Retention 990 1.0 1.0 no signal
876 Eye Pain 1,073 1.0 1.0 no signal
877 Loss Of Consciousness 2,477 1.0 1.0 no signal
878 Multiple Fractures 320 1.0 1.0 no signal
879 Incorrect Product Storage 257 1.0 1.0 no signal
880 Eye Discharge 196 1.0 1.0 no signal
881 Haemorrhage 2,002 1.0 1.0 no signal
882 Blood Potassium Decreased 576 1.0 1.0 no signal
883 Hyperglycaemia 693 1.0 1.0 no signal
884 Breast Cancer 1,793 1.0 1.0 no signal
885 Device Issue 1,651 0.9 0.9 no signal
886 Osteonecrosis Of Jaw 471 0.9 0.9 no signal
887 Tinnitus 865 0.9 0.9 no signal
888 Haematemesis 475 0.9 0.9 no signal
889 Arteriosclerosis 176 0.9 0.9 no signal
890 Dermatitis Contact 211 0.9 0.9 no signal
891 Haemorrhage Intracranial 278 0.9 0.9 no signal
892 Toxic Skin Eruption 187 0.9 0.9 no signal
893 Head Discomfort 323 0.9 0.9 no signal
894 Blindness 745 0.9 0.9 no signal
895 Feeling Abnormal 4,349 0.9 0.9 no signal
896 Underdose 1,319 0.9 0.9 no signal
897 Full Blood Count Abnormal 190 0.9 0.9 no signal
898 Jaundice 485 0.9 0.9 no signal
899 Lethargy 1,029 0.9 0.9 no signal
900 Anxiety 5,090 0.9 0.9 no signal
901 Glomerular Filtration Rate Decreased 216 0.9 0.9 no signal
902 Head Injury 562 0.9 0.9 no signal
903 Gastric Haemorrhage 206 0.9 0.9 no signal
904 Myocarditis 201 0.9 0.9 no signal
905 Eczema 892 0.9 0.9 no signal
906 Middle Insomnia 329 0.9 0.9 no signal
907 Central Nervous System Lesion 244 0.9 0.9 no signal
908 Presyncope 426 0.9 0.9 no signal
909 Palpitations 2,056 0.9 0.9 no signal
910 Cold Sweat 309 0.9 0.9 no signal
911 Unevaluable Event 1,323 0.9 0.9 no signal
912 Needle Issue 497 0.9 0.9 no signal
913 Micturition Urgency 197 0.9 0.9 no signal
914 Throat Tightness 468 0.9 0.9 no signal
915 Status Epilepticus 196 0.9 0.9 no signal
916 Injection Site Mass 636 0.9 0.9 no signal
917 Hyperhidrosis 2,223 0.9 0.9 no signal
918 Syncope 1,719 0.9 0.9 no signal
919 Incorrect Dose Administered 3,856 0.9 0.9 no signal
920 Arrhythmia 815 0.9 0.9 no signal
921 Anaphylactic Shock 439 0.9 0.9 no signal
922 Decreased Activity 183 0.9 0.9 no signal
923 Generalised Tonic-clonic Seizure 276 0.8 0.8 no signal
924 Restless Legs Syndrome 303 0.8 0.8 no signal
925 Blood Sodium Decreased 313 0.8 0.8 no signal
926 Dehydration 2,219 0.8 0.8 no signal
927 Rash Generalised 435 0.8 0.8 no signal
928 Cyanosis 261 0.8 0.8 no signal
929 Temperature Intolerance 169 0.8 0.8 no signal
930 Breast Pain 176 0.8 0.8 no signal
931 Face Oedema 278 0.8 0.8 no signal
932 Cerebral Haemorrhage 586 0.8 0.8 no signal
933 Breast Cancer Metastatic 175 0.8 0.8 no signal
934 Gastrointestinal Haemorrhage 1,365 0.8 0.8 no signal
935 Ocular Hyperaemia 755 0.8 0.8 no signal
936 Ischaemic Stroke 287 0.8 0.8 no signal
937 Pollakiuria 667 0.8 0.8 no signal
938 Metastases To Central Nervous System 205 0.8 0.8 no signal
939 Melaena 353 0.8 0.8 no signal
940 Myocardial Infarction 2,780 0.8 0.8 no signal
941 Faeces Discoloured 342 0.8 0.8 no signal
942 Depressed Mood 828 0.8 0.8 no signal
943 Hypersomnia 447 0.8 0.8 no signal
944 Bronchospasm 223 0.8 0.8 no signal
945 Product Prescribing Issue 316 0.8 0.8 no signal
946 Device Failure 235 0.8 0.8 no signal
947 Metastases To Bone 252 0.8 0.8 no signal
948 Blood Potassium Increased 249 0.8 0.8 no signal
949 Aspiration 166 0.8 0.8 no signal
950 Visual Acuity Reduced 513 0.8 0.8 no signal
951 Drug Dose Omission 2,560 0.8 0.8 no signal
952 Hyponatraemia 856 0.8 0.8 no signal
953 Circulatory Collapse 260 0.8 0.8 no signal
954 Ventricular Fibrillation 169 0.8 0.8 no signal
955 Post Procedural Haemorrhage 177 0.8 0.8 no signal
956 Sudden Death 162 0.8 0.8 no signal
957 Speech Disorder 791 0.8 0.8 no signal
958 Crying 549 0.8 0.8 no signal
959 Eye Swelling 556 0.7 0.7 no signal
960 Inappropriate Schedule Of Drug Administration 1,081 0.7 0.7 no signal
961 Hot Flush 1,129 0.7 0.7 no signal
962 Paraesthesia Oral 215 0.7 0.7 no signal
963 Muscle Tightness 242 0.7 0.7 no signal
964 Treatment Noncompliance 810 0.7 0.7 no signal
965 Ventricular Tachycardia 247 0.7 0.7 no signal
966 Cerebrovascular Accident 2,534 0.7 0.7 no signal
967 Dizziness Postural 143 0.7 0.7 no signal
968 Cardiac Failure Congestive 1,203 0.7 0.7 no signal
969 Nervousness 778 0.7 0.7 no signal
970 Tooth Loss 307 0.7 0.7 no signal
971 Upper Gastrointestinal Haemorrhage 248 0.7 0.7 no signal
972 Balance Disorder 1,271 0.7 0.7 no signal
973 Pneumonia Aspiration 365 0.7 0.7 no signal
974 Transfusion 153 0.7 0.7 no signal
975 Diabetes Mellitus Inadequate Control 257 0.7 0.7 no signal
976 Lip Swelling 481 0.7 0.7 no signal
977 Brain Injury 145 0.7 0.7 no signal
978 Vaginal Discharge 145 0.7 0.7 no signal
979 Cardiac Disorder 1,353 0.7 0.7 no signal
980 Seizure 1,646 0.7 0.7 no signal
981 Urinary Retention 476 0.7 0.7 no signal
982 Ventricular Extrasystoles 148 0.7 0.7 no signal
983 Therapy Cessation 726 0.7 0.7 no signal
984 Hypoacusis 610 0.7 0.7 no signal
985 Infusion Site Pain 181 0.7 0.7 no signal
986 Convulsion 820 0.7 0.7 no signal
987 Blood Calcium Decreased 159 0.7 0.7 no signal
988 Hepatic Encephalopathy 131 0.7 0.7 no signal
989 Bipolar Disorder 153 0.7 0.7 no signal
990 Blood Count Abnormal 213 0.7 0.7 no signal
991 Hypoaesthesia Oral 208 0.7 0.7 no signal
992 Eyelid Oedema 161 0.7 0.7 no signal
993 Vision Blurred 1,868 0.7 0.7 no signal
994 Metabolic Acidosis 432 0.7 0.7 no signal
995 Cardiovascular Disorder 349 0.7 0.7 no signal
996 Nocturia 165 0.7 0.7 no signal
997 Flatulence 771 0.7 0.7 no signal
998 Stevens-johnson Syndrome 302 0.7 0.7 no signal
999 Ocular Discomfort 147 0.7 0.7 no signal
1000 Pelvic Pain 246 0.7 0.7 no signal
1001 Somnolence 2,707 0.7 0.7 no signal
1002 Altered State Of Consciousness 290 0.7 0.7 no signal
1003 Acne 1,023 0.7 0.7 no signal
1004 Hepatitis C 164 0.7 0.7 no signal
1005 Product Dose Omission 887 0.7 0.7 no signal
1006 Cardiogenic Shock 191 0.7 0.7 no signal
1007 Blood Creatine Phosphokinase Increased 391 0.7 0.7 no signal
1008 Disorientation 528 0.7 0.7 no signal
1009 Therapy Interrupted 916 0.7 0.7 no signal
1010 Sluggishness 134 0.7 0.7 no signal
1011 Drug Effect Less Than Expected 186 0.7 0.7 no signal
1012 Product Administration Error 261 0.7 0.7 no signal
1013 Drug Effective For Unapproved Indication 382 0.7 0.7 no signal
1014 Thirst 233 0.7 0.7 no signal
1015 Intentional Product Misuse 1,132 0.6 0.6 no signal
1016 Product Dose Omission In Error 350 0.6 0.6 no signal
1017 Eye Pruritus 429 0.6 0.6 no signal
1018 Coma 620 0.6 0.6 no signal
1019 Retching 276 0.6 0.6 no signal
1020 Hypomagnesaemia 180 0.6 0.6 no signal
1021 Therapeutic Response Unexpected 584 0.6 0.6 no signal
1022 Cardiac Arrest 1,070 0.6 0.6 no signal
1023 Injury Associated With Device 259 0.6 0.6 no signal
1024 Hypotonia 129 0.6 0.6 no signal
1025 Pulmonary Arterial Hypertension 187 0.6 0.6 no signal
1026 Abortion Induced 121 0.6 0.6 no signal
1027 Brain Fog 187 0.6 0.6 no signal
1028 Mental Disorder 557 0.6 0.6 no signal
1029 Fluid Overload 188 0.6 0.6 no signal
1030 Angioedema 557 0.6 0.6 no signal
1031 Initial Insomnia 128 0.6 0.6 no signal
1032 Tremor 2,085 0.6 0.6 no signal
1033 Erythema Multiforme 116 0.6 0.6 no signal
1034 Constipation 2,691 0.6 0.6 no signal
1035 Chromaturia 274 0.6 0.6 no signal
1036 Panic Attack 440 0.6 0.6 no signal
1037 Hyperthyroidism 174 0.6 0.6 no signal
1038 Product Availability Issue 269 0.6 0.6 no signal
1039 Dementia 332 0.6 0.6 no signal
1040 Chronic Kidney Disease 911 0.6 0.6 no signal
1041 Emotional Disorder 366 0.6 0.6 no signal
1042 Internal Haemorrhage 135 0.6 0.6 no signal
1043 Choking 229 0.6 0.6 no signal
1044 Unresponsive To Stimuli 302 0.6 0.6 no signal
1045 Flushing 1,197 0.6 0.6 no signal
1046 Abortion Spontaneous 470 0.6 0.6 no signal
1047 Product Dispensing Error 253 0.6 0.6 no signal
1048 Malignant Neoplasm Progression 1,176 0.6 0.6 no signal
1049 Dialysis 164 0.6 0.6 no signal
1050 Cognitive Disorder 536 0.6 0.6 no signal
1051 Depressed Level Of Consciousness 453 0.6 0.6 no signal
1052 Cardio-respiratory Arrest 481 0.6 0.6 no signal
1053 Breast Cancer Female 307 0.6 0.6 no signal
1054 Hunger 153 0.6 0.6 no signal
1055 Neoplasm Progression 396 0.6 0.6 no signal
1056 Product Dose Omission Issue 3,208 0.6 0.6 no signal
1057 Menorrhagia 224 0.6 0.6 no signal
1058 Hypothermia 114 0.6 0.6 no signal
1059 Blood Glucose Abnormal 208 0.6 0.6 no signal
1060 Anosmia 162 0.6 0.6 no signal
1061 Apathy 162 0.6 0.6 no signal
1062 Hypoglycaemia 535 0.5 0.5 no signal
1063 Gastrointestinal Carcinoma 101 0.5 0.5 no signal
1064 Vaginal Haemorrhage 467 0.5 0.5 no signal
1065 Mental Impairment 266 0.5 0.5 no signal
1066 Bone Loss 166 0.5 0.5 no signal
1067 Fear 291 0.5 0.5 no signal
1068 Feeling Jittery 205 0.5 0.5 no signal
1069 Dysgeusia 794 0.5 0.5 no signal
1070 Ageusia 263 0.5 0.5 no signal
1071 Foetal Exposure During Pregnancy 830 0.5 0.5 no signal
1072 Dry Skin 1,341 0.5 0.5 no signal
1073 Mood Swings 322 0.5 0.5 no signal
1074 Poisoning 127 0.5 0.5 no signal
1075 Hospitalisation 1,532 0.5 0.5 no signal
1076 Device Defective 162 0.5 0.5 no signal
1077 Bradycardia 527 0.5 0.5 no signal
1078 Increased Appetite 184 0.5 0.5 no signal
1079 Blood Thyroid Stimulating Hormone Increased 90 0.5 0.5 no signal
1080 Impaired Driving Ability 110 0.5 0.5 no signal
1081 Eye Irritation 535 0.5 0.5 no signal
1082 Full Blood Count Decreased 193 0.5 0.5 no signal
1083 Orthostatic Hypotension 166 0.5 0.5 no signal
1084 Suicidal Ideation 863 0.5 0.5 no signal
1085 Psychotic Disorder 278 0.5 0.5 no signal
1086 Disturbance In Attention 506 0.5 0.5 no signal
1087 Amenorrhoea 156 0.5 0.5 no signal
1088 Hair Texture Abnormal 126 0.5 0.5 no signal
1089 International Normalised Ratio Increased 268 0.5 0.5 no signal
1090 Personality Change 87 0.5 0.5 no signal
1091 Prostate Cancer 755 0.5 0.5 no signal
1092 Meningioma 136 0.5 0.5 no signal
1093 Insurance Issue 136 0.5 0.5 no signal
1094 Multiple Sclerosis 436 0.4 0.4 no signal
1095 Therapy Change 87 0.4 0.4 no signal
1096 Irritability 542 0.4 0.4 no signal
1097 Mood Altered 244 0.4 0.4 no signal
1098 Exposure Via Skin Contact 203 0.4 0.4 no signal
1099 Prostatic Specific Antigen Increased 123 0.4 0.4 no signal
1100 Device Deployment Issue 106 0.4 0.4 no signal
1101 Product Quality Issue 1,170 0.4 0.4 no signal
1102 Palmar-plantar Erythrodysaesthesia Syndrome 201 0.4 0.4 no signal
1103 Respiratory Arrest 239 0.4 0.4 no signal
1104 Accidental Exposure To Product 854 0.4 0.4 no signal
1105 Complication Associated With Device 111 0.4 0.4 no signal
1106 Thinking Abnormal 157 0.4 0.4 no signal
1107 Nightmare 287 0.4 0.4 no signal
1108 Muscle Rigidity 98 0.4 0.4 no signal
1109 Dyskinesia 332 0.4 0.4 no signal
1110 Overdose 1,768 0.4 0.4 no signal
1111 Premature Baby 246 0.4 0.4 no signal
1112 Blood Glucose Increased 1,531 0.4 0.4 no signal
1113 Muscle Twitching 183 0.4 0.4 no signal
1114 Drug Reaction With Eosinophilia And Systemic Symptoms 202 0.4 0.4 no signal
1115 Mydriasis 101 0.4 0.4 no signal
1116 Drug Exposure During Pregnancy 270 0.4 0.4 no signal
1117 Eructation 148 0.4 0.4 no signal
1118 Glycosylated Haemoglobin Increased 196 0.4 0.4 no signal
1119 Premature Delivery 124 0.4 0.4 no signal
1120 Drug Prescribing Error 150 0.4 0.4 no signal
1121 Lactic Acidosis 247 0.4 0.4 no signal
1122 Hyperkalaemia 268 0.4 0.4 no signal
1123 Sinus Bradycardia 74 0.4 0.4 no signal
1124 Sexual Dysfunction 89 0.4 0.4 no signal
1125 Agitation 556 0.4 0.4 no signal
1126 Incorrect Product Administration Duration 152 0.4 0.4 no signal
1127 Euphoric Mood 77 0.4 0.4 no signal
1128 Wrong Technique In Product Usage Process 1,502 0.4 0.4 no signal
1129 Pancreatic Carcinoma 216 0.4 0.4 no signal
1130 Drug Administration Error 227 0.4 0.4 no signal
1131 Gastric Cancer 186 0.4 0.4 no signal
1132 Salivary Hypersecretion 72 0.4 0.4 no signal
1133 Device Mechanical Issue 93 0.4 0.4 no signal
1134 Restlessness 264 0.4 0.4 no signal
1135 Psychomotor Hyperactivity 117 0.3 0.3 no signal
1136 Madarosis 82 0.3 0.3 no signal
1137 Skin Burning Sensation 488 0.3 0.3 no signal
1138 Breast Cancer Stage I 64 0.3 0.3 no signal
1139 Syringe Issue 119 0.3 0.3 no signal
1140 Blood Glucose Decreased 325 0.3 0.3 no signal
1141 Drug Dispensing Error 104 0.3 0.3 no signal
1142 Myoclonus 80 0.3 0.3 no signal
1143 Device Leakage 284 0.3 0.3 no signal
1144 Renal Injury 200 0.3 0.3 no signal
1145 Skin Irritation 303 0.3 0.3 no signal
1146 Hallucination, Auditory 105 0.3 0.3 no signal
1147 Skeletal Injury 69 0.3 0.3 no signal
1148 Product Storage Error 570 0.3 0.3 no signal
1149 Dysmenorrhoea 85 0.3 0.3 no signal
1150 Incorrect Dose Administered By Device 164 0.3 0.3 no signal
1151 Hair Colour Changes 81 0.3 0.3 no signal
1152 Device Occlusion 89 0.3 0.3 no signal
1153 Delusion 99 0.3 0.3 no signal
1154 Drug Administered At Inappropriate Site 68 0.3 0.3 no signal
1155 Hallucination, Visual 132 0.3 0.3 no signal
1156 Hallucination 467 0.3 0.3 no signal
1157 Caesarean Section 73 0.3 0.3 no signal
1158 Diabetic Ketoacidosis 148 0.3 0.3 no signal
1159 No Adverse Event 1,084 0.3 0.3 no signal
1160 Anger 206 0.3 0.3 no signal
1161 Incorrect Route Of Drug Administration 216 0.3 0.3 no signal
1162 Hereditary Angioedema 62 0.3 0.3 no signal
1163 Death 5,051 0.3 0.3 no signal
1164 Product Packaging Issue 54 0.3 0.3 no signal
1165 Device Dislocation 251 0.3 0.3 no signal
1166 Libido Decreased 71 0.3 0.3 no signal
1167 Plasma Cell Myeloma 223 0.3 0.3 no signal
1168 End Stage Renal Disease 105 0.3 0.3 no signal
1169 Bladder Cancer 330 0.3 0.3 no signal
1170 Suicide Attempt 336 0.3 0.3 no signal
1171 Device Delivery System Issue 143 0.3 0.3 no signal
1172 Metrorrhagia 94 0.3 0.3 no signal
1173 Erectile Dysfunction 139 0.3 0.3 no signal
1174 Electrocardiogram Qt Prolonged 191 0.3 0.3 no signal
1175 Rhabdomyolysis 216 0.3 0.3 no signal
1176 Dermatitis Atopic 256 0.3 0.3 no signal
1177 Hepatic Cancer 123 0.3 0.2 no signal
1178 Oesophageal Carcinoma 150 0.2 0.2 no signal
1179 Parkinsonism 48 0.2 0.2 no signal
1180 Emotional Distress 592 0.2 0.2 no signal
1181 Mania 80 0.2 0.2 no signal
1182 Abnormal Behaviour 194 0.2 0.2 no signal
1183 Serotonin Syndrome 93 0.2 0.2 no signal
1184 Abnormal Dreams 134 0.2 0.2 no signal
1185 Aggression 240 0.2 0.2 no signal
1186 Blood Glucose Fluctuation 52 0.2 0.2 no signal
1187 Product Complaint 115 0.2 0.2 no signal
1188 Circumstance Or Information Capable Of Leading To Medication Error 153 0.2 0.2 no signal
1189 Menstruation Irregular 120 0.2 0.2 no signal
1190 Paranoia 78 0.2 0.2 no signal
1191 Renal Cancer 215 0.2 0.2 no signal
1192 Product Use Complaint 67 0.2 0.2 no signal
1193 Expired Product Administered 143 0.2 0.2 no signal
1194 Device Breakage 169 0.2 0.2 no signal
1195 Wrong Technique In Device Usage Process 193 0.2 0.2 no signal
1196 Poor Quality Product Administered 42 0.2 0.2 no signal
1197 Product Packaging Quantity Issue 43 0.2 0.2 no signal
1198 Withdrawal Syndrome 165 0.2 0.2 no signal
1199 Product Substitution Issue 220 0.2 0.2 no signal
1200 Dystonia 74 0.2 0.2 no signal
1201 Economic Problem 58 0.2 0.2 no signal
1202 Product Administered At Inappropriate Site 67 0.2 0.2 no signal
1203 Inability To Afford Medication 36 0.2 0.2 no signal
1204 Application Site Pain 80 0.2 0.2 no signal
1205 Drug Dependence 561 0.2 0.2 no signal
1206 Respiratory Depression 42 0.2 0.2 no signal
1207 Device Difficult To Use 225 0.2 0.2 no signal
1208 Menstruation Delayed 35 0.2 0.2 no signal
1209 Incorrect Drug Administration Duration 88 0.2 0.2 no signal
1210 Sedation 78 0.1 0.1 no signal
1211 Intentional Overdose 185 0.1 0.1 no signal
1212 Application Site Erythema 74 0.1 0.1 no signal
1213 Schizophrenia 31 0.1 0.1 no signal
1214 Anhedonia 67 0.1 0.1 no signal
1215 Product Preparation Error 51 0.1 0.1 no signal
1216 Extra Dose Administered 98 0.1 0.1 no signal
1217 Gynaecomastia 75 0.1 0.1 no signal
1218 Pharmaceutical Product Complaint 62 0.1 0.1 no signal
1219 Peritonitis Bacterial 23 0.1 0.1 no signal
1220 Device Use Error 77 0.1 0.1 no signal
1221 Intentional Drug Misuse 47 0.1 0.1 no signal
1222 Application Site Pruritus 50 0.1 0.1 no signal
1223 Drug Dose Omission By Device 159 0.1 0.1 no signal
1224 Device Use Issue 34 0.1 0.1 no signal
1225 Drug Abuse 163 0.1 0.1 no signal
1226 Genital Haemorrhage 25 0.1 0.1 no signal
1227 Sickle Cell Anaemia With Crisis 30 0.1 0.1 no signal
1228 Intentional Self-injury 38 0.1 0.1 no signal
1229 Multiple Sclerosis Relapse 127 0.1 0.1 no signal
1230 Unintended Pregnancy 19 0.1 0.1 no signal
1231 Abnormal Weight Gain 22 0.1 0.1 no signal
1232 Product Taste Abnormal 21 0.1 0.1 no signal
1233 Akathisia 21 0.1 0.1 no signal
1234 Completed Suicide 125 0.1 0.1 no signal
1235 Application Site Rash 20 0.1 0.1 no signal
1236 Tardive Dyskinesia 41 0.1 0.1 no signal
1237 Product Physical Issue 28 0.1 0.1 no signal
1238 Extrapyramidal Disorder 35 0.1 0.1 no signal
1239 Hospice Care 13 0.1 0.1 no signal
1240 Poisoning Deliberate 12 0.1 0.1 no signal
1241 Product Odour Abnormal 13 0.1 0.1 no signal
1242 Drug Withdrawal Syndrome 109 0.1 0.1 no signal
1243 Sopor 16 0.1 0.1 no signal
1244 Colorectal Cancer 51 0.1 0.1 no signal
1245 Application Site Irritation 13 0.1 0.1 no signal
1246 Product Adhesion Issue 36 0.0 0.0 no signal
1247 Neuroleptic Malignant Syndrome 12 0.0 0.0 no signal
1248 Complication Of Device Insertion 16 0.0 0.0 no signal
1249 Accidental Underdose 10 0.0 0.0 no signal
1250 Dependence 37 0.0 0.0 no signal
1251 Embedded Device 6 0.0 0.0 no signal
1252 Complication Of Device Removal 8 0.0 0.0 no signal
1253 Device Adhesion Issue 7 0.0 0.0 no signal
1254 Unintentional Medical Device Removal 5 0.0 0.0 no signal
1255 Device Expulsion 14 0.0 0.0 no signal