Reaction

Heart Disease Congenital reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,525 reports · 72 co-occurring drugs

As of the last recalculation, Heart Disease Congenital appears in 3,525 FAERS reports alongside 72 co-occurring drug terms. The strongest observed disproportionality signal is PAROXETINE HYDROCHLORIDE (PRR 42.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Paroxetine Hydrochloride	555	42.6	42.8
Misoprostol	62	38.3	38.5
Zidovudine	52	23.3	23.4
Darunavir	55	21.8	21.9
Nicotine Polacrilex Mini	54	21.6	21.6
Nicotine Polarilex	54	21.6	21.6
Dalteparin Sodium	36	20.3	20.4
Ritonavir	83	17.2	17.2
Ritonavir 100 Mg	35	14.0	14.0
Sertraline Hydrochloride	258	13.8	13.8
Divalproex Sodium	105	13.7	13.7
Valproate Sodium	47	13.6	13.6
Palivizumab	33	12.8	12.8
Ampicillin	15	10.7	10.8
Ampicillin Sodium	15	10.7	10.8
Atazanavir	25	10.3	10.4
Ondansetron Hydrochloride	201	10.2	10.2
Raltegravir	26	9.4	9.4
Nicotine	59	8.7	8.8
Ondansetron	152	8.5	8.5
Ondansetron Tablets	152	8.5	8.5
Nicotine Polacrilex	54	8.4	8.5
Lopinavir And Ritonavir	19	8.3	8.3
Promethazine Hydrochloride	26	8.3	8.3
Epoetin Alfa	16	8.0	8.0
Torsemide	44	7.9	7.9
Tenofovir Disoproxil Fumarate Tablets	10	6.9	6.9
Thiamine Hydrochloride	14	6.7	6.7
Sertraline	120	6.2	6.2
Miconazole Nitrate	9	6.1	6.1
Valproic Acid	32	6.0	6.0
Methadone Hydrochloride	11	6.0	6.0
Phenytoin	21	6.0	6.0
Hydrocodone Bitartrate And Acetaminophen	54	5.7	5.7
Bleomycin Sulfate	10	5.7	5.7
Fluoxetine Hydrochloride	114	5.4	5.4
Enoxaparin Sodium	52	5.4	5.4
Carbamazepine	60	5.4	5.4
Emtricitabine And Tenofovir Disoproxil Fumarate	41	5.4	5.4
Paroxetine Hydrochloride Hemihydrate	29	5.2	5.2
Paroxetine	29	5.1	5.1
Ezetimibe	63	5.0	5.0
Indomethacin	11	4.9	4.9
Ramipril	100	4.9	4.9
Bosentan	41	4.8	4.9
Fluoxetine	54	4.8	4.8
Clobazam	19	4.6	4.6
Methimazole	6	4.5	4.5
Tacrolimus Ointment 0.1%	89	4.3	4.3
Tacrolimus Extended-Release Capsules	89	4.3	4.3
Lamotirigine	51	4.3	4.3
Lamotrigine Extended-Release	51	4.3	4.3
Lamotrigine Chewable Dispersible	51	4.3	4.3
Hydroxychloroquine	53	4.2	4.2
Venlafaxine Hydrochloride	92	4.2	4.2
Oxazepam	15	4.1	4.1
Ibuprofen And Diphenhydramine Citrate	16	4.1	4.1
Vigabatrin	10	4.1	4.1
Lamotrigine	87	4.0	4.0
Tacrolimus	103	4.0	4.0
Methadone	28	3.9	3.9
Lamivudine	20	3.8	3.8
Levetiracetam In Sodium Chloride	47	3.6	3.6
Levetiracetam Oral	47	3.6	3.6
Levetiracetam Injection	47	3.6	3.6
Lamivudine Oral	14	3.3	3.3
Levetiracetam	65	2.9	2.9
Tenofovir Disoproxil Fumarate	15	2.7	2.7
Isotretinoin	19	2.3	2.3
Oxycodone Hydrochloride	75	2.1	2.1
Hydrocodone Bitartrate	14	1.9	1.9
Oxymorphone Hydrochloride	3	1.5	1.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.