Reaction

Hyperprolactinaemia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,417 reports · 79 co-occurring drugs

As of the last recalculation, Hyperprolactinaemia appears in 6,417 FAERS reports alongside 79 co-occurring drug terms. The strongest observed disproportionality signal is RISPERIDONE (PRR 360.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Risperidone	4,483	360.6	373.2
Paliperidone	1,268	219.5	232.2
Paliperidone Palmitate	355	37.8	38.2
Aripiprazole Oral	429	36.0	36.4
Aripiprazole Orally Disintegrating	429	36.0	36.4
Haloperidol	255	35.4	35.8
Haloperidol Lactate	257	35.0	35.4
Olanzapine	655	21.9	22.0
Aripiprazole	655	19.2	19.3
Lithium	109	14.2	14.3
Lithium Bromatum	109	14.2	14.3
Ziprasidone	57	10.6	10.6
Olanzapine Pamoate	116	9.3	9.4
Cariprazine	26	9.1	9.1
Ziprasidone Mesylate	39	8.9	8.9
Quetiapine	480	8.7	8.7
Quetiapine Fumarate	74	8.2	8.2
Brexpiprazole	41	8.1	8.1
Lurasidone Hydrochloride	48	7.5	7.5
Valproate Sodium	43	6.8	6.8
Lithium Carbonate	34	6.5	6.5
Valproic Acid	55	5.7	5.7
Divalproex Sodium	80	5.6	5.6
Clozapine	208	5.5	5.5
Paroxetine Hydrochloride Hemihydrate	56	5.5	5.5
Paroxetine	56	5.4	5.4
Guanfacine	13	5.4	5.4
Methylphenidate Hydrochloride	83	4.6	4.6
Venlafaxine	95	4.4	4.4
Fluoxetine	84	4.1	4.1
Sertraline	138	3.9	3.9
Doxepin	12	3.8	3.8
Sumatriptan Succinate	29	3.7	3.7
Cenobamate	9	3.5	3.5
Tranexamic Acid	9	3.3	3.3
Fluoxetine Hydrochloride	126	3.2	3.2
Clonazepam	154	3.2	3.2
Paroxetine Hydrochloride	86	3.1	3.1
Doxepin Hydrochloride	12	3.1	3.1
Mirtazapine	84	3.0	3.0
Venlafaxine Hydrochloride	120	3.0	3.0
Metoclopramide	50	3.0	3.0
Escitslopram	52	2.9	2.9
Testosterone Cypionate	8	2.9	2.9
Methylphenidate	25	2.8	2.8
Itraconazole	10	2.8	2.8
Carbamazepine	57	2.8	2.8
Desloratadine	9	2.7	2.7
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	28	2.6	2.6
Vortioxetine	13	2.5	2.5
Escitalopram Oxalate	55	2.5	2.5
Citalopram Hydrobromide	79	2.4	2.4
Diazepam Oral Solution (Concentrate)	65	2.4	2.4
Diazepam Oral	65	2.4	2.4
Testosterone	17	2.4	2.4
Sumatriptan	27	2.3	2.3
Asenapine Maleate	6	2.2	2.2
Lamotirigine	49	2.2	2.2
Lamotrigine Extended-Release	49	2.2	2.2
Lamotrigine Chewable Dispersible	49	2.2	2.2
Metoclopramide Hydrochloride	52	2.2	2.2
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	28	2.2	2.2
Atomoxetine Hydrochloride	16	2.2	2.2
Progesterone	15	2.1	2.1
Oxazepam	14	2.1	2.1
Estradiol Gel 0.1%	28	2.0	2.0
Estradiol Transdermal	28	2.0	2.0
Oxcarbazepine	20	2.0	2.0
Bupropion	27	2.0	2.0
Clobazam	14	1.9	1.9
Ivacaftor	4	1.6	1.6
Orlistat	13	1.6	1.6
Amphetamine	4	1.6	1.6
Brivaracetam	4	1.4	1.4
Suvorexant	5	1.3	1.3
Medroxyprogesterone Acetate	13	0.8	0.8
Rimegepant Sulfate	3	0.8	0.8
Vigabatrin	3	0.7	0.7
Etonogestrel	7	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.