Reaction

Sudden Cardiac Death reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,384 reports · 62 co-occurring drugs

As of the last recalculation, Sudden Cardiac Death appears in 3,384 FAERS reports alongside 62 co-occurring drug terms. The strongest observed disproportionality signal is METHADONE HYDROCHLORIDE (PRR 13.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Methadone Hydrochloride	23	13.2	13.2
Dronedarone	15	9.1	9.1
Methadone	62	9.1	9.1
Paricalcitol	19	8.3	8.3
Olanzapine	137	8.1	8.1
Eplerenone	16	7.7	7.7
Haloperidol	28	7.1	7.1
Haloperidol Lactate	28	7.0	7.0
Testosterone Cypionate	10	6.9	6.9
Testosterone	25	6.6	6.6
Agalsidase Beta	9	6.0	6.0
Atropine	8	6.0	6.0
Trazodone Hydrochloride	15	5.9	5.9
Dalteparin Sodium	10	5.8	5.8
Sildenafil Powder,	33	5.7	5.8
Theophylline Anhydrous	11	5.5	5.5
Lopinavir And Ritonavir	12	5.5	5.5
Tramadol Hydrochloride	33	5.4	5.4
Theophylline	10	5.4	5.4
Erythromycin	16	5.3	5.3
Oxazepam	18	5.2	5.2
Digoxin	58	5.0	5.0
Isosorbide Mononitrate	16	4.8	4.8
Epoetin Alfa	9	4.7	4.7
Torsemide	25	4.7	4.7
Ramipril	89	4.5	4.5
Diclofenac Sodium 1%	26	4.5	4.5
Diclofenac Sodium Topical	26	4.5	4.5
Sildenafil	42	4.5	4.5
Diclofenac Sodium Topical Gel, 1%	26	4.5	4.5
Aripiprazole	86	4.4	4.4
Mirtazapine	64	4.4	4.4
Aripiprazole Oral	29	4.3	4.3
Aripiprazole Orally Disintegrating	29	4.3	4.3
Bosentan	34	4.2	4.2
Ranolazine	7	4.1	4.1
Sotalol Hydrochloride	11	4.1	4.1
Methoxy Polyethylene Glycol-Epoetin Beta	7	3.9	3.9
Quinapril Hydrochloride	5	3.9	3.9
Sacubitril And Valsartan	71	3.8	3.8
Prasugrel Hydrochloride	6	3.6	3.6
Bleomycin Sulfate	6	3.6	3.6
Ziprasidone Mesylate	8	3.5	3.5
Sildenafil Citrate	65	3.2	3.2
Ziprasidone	9	3.1	3.1
Bortezomib	45	3.1	3.1
Tolvaptan	7	3.0	3.0
Dofetilide	5	2.9	2.9
Paliperidone	11	2.9	2.9
Thalidomide	17	2.9	2.9
Olaparib	9	2.7	2.7
Tafamidis	5	2.6	2.6
Ibrutinib	34	2.6	2.6
Clozapine	52	2.6	2.6
Daratumumab	16	2.5	2.5
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	12	2.4	2.4
Derma Foam Excel Hand Sanitizer	3	2.3	2.3
Ethanol	3	2.3	2.3
Pemetrexed	8	2.3	2.3
Sevelamer Carbonate	4	2.1	2.1
Acalabrutinib	4	2.0	2.0
Patiromer	4	1.8	1.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.