Reaction

Acne Cystic reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,985 reports · 38 co-occurring drugs

As of the last recalculation, Acne Cystic appears in 2,985 FAERS reports alongside 38 co-occurring drug terms. The strongest observed disproportionality signal is ADAPALENE (PRR 106.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Adapalene	1,447	106.6	107.4
Sulfur	104	89.1	90.2
Salicylic Acid	378	56.9	57.3
Anakinra	80	34.5	34.7
Elexacaftor, Tezacaftor, And Ivacaftor	24	13.5	13.5
Tretinoin	15	12.9	13.0
Isotretinoin	75	10.8	10.8
Dapsone	11	7.2	7.2
Upadacitinib	81	7.1	7.1
Levonorgestrel	160	5.8	5.8
Leflunomide	82	5.6	5.6
Naproxen Sodium Tablet, Coated	10	5.2	5.2
Naproxen Sodium, Coated Tablets	10	5.2	5.2
Naproxen Sodium 220Mg	10	5.2	5.2
Minocycline	8	4.8	4.8
Tofacitinib	109	4.2	4.2
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	25	4.2	4.2
Abatacept	80	4.1	4.1
Etonogestrel And Ethinyl Estradiol	13	4.1	4.1
Lisdexamfetamine Dimesylate	19	4.0	4.0
Fesoterodine Fumarate	6	3.9	3.9
Multivitamin	26	3.6	3.6
Dornase Alfa	10	3.6	3.6
Bimekizumab	9	3.0	3.0
Etonogestrel	20	2.9	2.9
Rimegepant Sulfate	5	2.8	2.8
Naltrexone Hydrochloride And Bupropion Hydrochloride	3	2.5	2.5
Fremanezumab-Vfrm	4	2.4	2.4
Drospirenone And Ethinyl Estradiol	15	2.4	2.4
Vismodegib	3	2.4	2.4
Lurasidone Hydrochloride	7	2.3	2.3
Copper	14	2.3	2.3
Botulinum Toxin Type A	4	2.2	2.2
Medroxyprogesterone Acetate	14	2.0	2.0
Vemurafenib	3	1.7	1.7
Nemolizumab-Ilto	3	1.6	1.6
Minoxidil	6	0.9	0.9
Dupilumab	54	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.