Reaction

Blood Prolactin Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,664 reports · 64 co-occurring drugs

As of the last recalculation, Blood Prolactin Increased appears in 4,664 FAERS reports alongside 64 co-occurring drug terms. The strongest observed disproportionality signal is PALIPERIDONE PALMITATE (PRR 162.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Paliperidone Palmitate	938	162.6	167.4
Paliperidone	394	82.3	83.7
Risperidone	1,533	76.2	77.0
Lurasidone Hydrochloride	131	28.7	28.9
Ziprasidone	110	28.5	28.7
Cariprazine	50	24.2	24.3
Ziprasidone Mesylate	76	24.2	24.3
Olanzapine	451	20.6	20.7
Olanzapine Pamoate	178	20.1	20.2
Brexpiprazole	69	18.8	18.9
Aripiprazole Oral	150	16.7	16.8
Aripiprazole Orally Disintegrating	150	16.7	16.8
Asenapine Maleate	28	14.5	14.5
Haloperidol	77	14.4	14.4
Haloperidol Lactate	78	14.3	14.3
Aripiprazole	362	14.2	14.3
Quetiapine Fumarate	92	14.2	14.2
Lithium	77	13.8	13.9
Lithium Bromatum	77	13.8	13.9
Lithium Carbonate	48	12.7	12.8
Quetiapine	384	9.6	9.6
Divalproex Sodium	96	9.4	9.4
Clozapine	216	8.0	8.0
Valproate Sodium	29	6.3	6.3
Clonidine	68	6.0	6.0
Lamotirigine	93	5.9	5.9
Lamotrigine Extended-Release	93	5.9	5.9
Lamotrigine Chewable Dispersible	93	5.9	5.9
Thiamine Hydrochloride	16	5.8	5.8
Guanfacine	9	5.1	5.1
Sertraline	127	4.9	4.9
Octreotide Acetate	33	4.8	4.8
Lamotrigine	139	4.8	4.8
Fluoxetine	71	4.8	4.8
Itraconazole	12	4.6	4.6
Valproic Acid	31	4.4	4.4
Fluoxetine Hydrochloride	121	4.3	4.3
Lorazepam	164	4.2	4.2
Topiramate	85	4.1	4.1
Sertraline Hydrochloride	101	3.9	3.9
Escitslopram	49	3.8	3.8
Atomoxetine Hydrochloride	20	3.8	3.8
Oxcarbazepine	27	3.7	3.7
Midazolam Hydrochloride	21	3.5	3.5
Escitalopram Oxalate	55	3.4	3.4
Mirtazapine	67	3.3	3.3
Clonazepam	115	3.3	3.3
Vortioxetine	12	3.2	3.2
Melatonin	38	3.1	3.1
Midazolam	17	3.0	3.0
Ritonavir 100 Mg	9	2.7	2.7
Darunavir	9	2.7	2.7
Lanreotide Acetate	4	2.3	2.3
Lisdexamfetamine Dimesylate	16	2.2	2.2
Naltrexone	14	2.0	2.0
Testosterone Cypionate	4	2.0	2.0
Somatropin	32	2.0	2.0
Desvenlafaxine Succinate	11	1.8	1.8
Medroxyprogesterone Acetate	17	1.5	1.5
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	3	1.3	1.3
Drospirenone And Ethinyl Estradiol	10	1.0	1.0
Valbenazine	5	0.9	0.9
Levonorgestrel	25	0.6	0.6
Copper	3	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.