Reaction

Temporomandibular Joint Syndrome reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,676 reports · 59 co-occurring drugs

As of the last recalculation, Temporomandibular Joint Syndrome appears in 2,676 FAERS reports alongside 59 co-occurring drug terms. The strongest observed disproportionality signal is ALENDRONATE SODIUM (PRR 40.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Alendronate Sodium	443	40.7	40.9
Risedronate Sodium	56	14.3	14.3
Raloxifene Hydrochloride	25	13.4	13.5
Denosumab	264	11.1	11.2
Sodium Oxybate	85	10.3	10.3
Rizatriptan Benzoate	12	9.2	9.2
Conjugated Estrogens	65	8.9	8.9
Butalbital, Acetaminophen, And Caffeine	12	8.8	8.8
Estrogens, Conjugated	64	8.6	8.6
Methocarbamol	24	8.3	8.3
Meclizine Hcl 12.5Mg	14	8.0	8.0
Meclizine Hcl 25Mg	14	8.0	8.0
Meclizine Hcl 12.5 Mg	14	8.0	8.0
Meclizine Hcl 25 Mg	14	8.0	8.0
Zoledronic Acid	39	7.7	7.7
Meclizine	15	7.2	7.2
Clindamycin	25	6.9	6.9
Amlodipine Besylate And Benazepril Hydrochloride	8	6.8	6.8
Tretinoin	7	6.7	6.7
Ezetimibe And Simvastatin	13	6.7	6.7
Armodafinil	18	6.7	6.7
Modafinil	27	6.6	6.6
Carisoprodol	16	6.6	6.6
Ibuprofen And Diphenhydramine Citrate	19	6.4	6.4
Romosozumab-Aqqg	11	6.3	6.3
Teriparatide	89	6.3	6.3
Ciprofloxacin Hydrochloride And Hydrocortisone	16	6.0	6.0
Meclizine Hydrochloride	15	6.0	6.0
Biotin	23	5.8	5.8
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	26	5.8	5.8
Sumatriptan	27	5.6	5.6
Ado-Trastuzumab Emtansine	6	5.5	5.5
Conjugated Estrogens And Medroxyprogesterone Acetate	16	5.3	5.3
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	28	5.3	5.3
Etonogestrel And Ethinyl Estradiol	15	5.3	5.3
Azelastine	12	5.2	5.2
Thyroid, Porcine	7	5.1	5.1
Cetirizine Hcl	6	5.1	5.1
Vilazodone Hydrochloride	6	5.1	5.1
Sumatriptan Succinate	16	4.9	4.9
Selexipag	16	4.8	4.8
Fexofenadine Hydrochloride	13	4.7	4.7
Asfotase Alfa	6	4.7	4.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	5	4.5	4.5
Lisdexamfetamine Dimesylate	19	4.5	4.5
Desvenlafaxine Succinate	15	4.3	4.3
Lapatinib	8	4.0	4.0
Acetaminophen, Aspirin (Nsaid) And Caffeine	8	3.7	3.7
Vortioxetine	8	3.7	3.7
Onabotulinumtoxina	36	3.7	3.7
Acetaminophen, Aspirin, And Caffeine	9	3.3	3.3
Lifitegrast	6	2.9	2.9
Hydrocodone Bitartrate And Acetaminophen	20	2.8	2.8
Medroxyprogesterone Acetate	17	2.7	2.7
Lurasidone Hydrochloride	7	2.6	2.6
Botulinum Toxin Type A	4	2.5	2.5
Benralizumab	6	2.3	2.3
Erenumab-Aooe	10	1.4	1.4
Adapalene	3	0.1	0.1

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.