Reaction

Trigeminal Neuralgia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,973 reports · 93 co-occurring drugs

As of the last recalculation, Trigeminal Neuralgia appears in 3,973 FAERS reports alongside 93 co-occurring drug terms. The strongest observed disproportionality signal is CARBAMAZEPINE (PRR 47.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Carbamazepine	531	47.8	48.1
Oxcarbazepine	158	26.5	26.6
Siponimod	36	21.3	21.4
Teriflunomide	139	16.7	16.7
Dalfampridine	197	15.1	15.1
Interferon Beta-1A	470	14.3	14.4
Ocrelizumab	155	13.6	13.6
Baclofen	207	13.2	13.3
Fingolimod Hcl	197	12.5	12.5
Natalizumab	380	12.0	12.0
Eptinezumab-Jjmr	20	11.6	11.6
Diroximel Fumarate	25	11.1	11.1
Alemtuzumab	33	9.0	9.0
Dimethyl Fumarate	201	9.0	9.0
Peginterferon Beta-1A	22	8.8	8.8
Interferon Beta-1B	31	8.5	8.5
Dimenhydrinate	16	7.9	7.9
Modafinil	47	7.7	7.7
Oxybutynin Chloride	12	7.2	7.2
Glatiramer Acetate	80	7.1	7.1
Ofatumumab	42	6.7	6.7
Pregabalin	319	6.6	6.6
Gabapentin	412	6.5	6.5
Dutasteride	10	6.5	6.5
Tizanidine Hydrochloride	21	6.1	6.1
Calcium, Magnesium, Potassium, And Sodium Oxybates	10	6.1	6.1
Dronabinol	9	5.9	5.9
Ozanimod Hydrochloride	9	5.7	5.7
Cyanocobalamin	34	5.4	5.5
Meclizine Hcl 12.5Mg	14	5.4	5.4
Meclizine Hcl 25Mg	14	5.4	5.4
Meclizine Hcl 12.5 Mg	14	5.4	5.4
Meclizine Hcl 25 Mg	14	5.4	5.4
Methimazole	8	5.3	5.4
Primidone	10	5.2	5.2
Meclizine Hydrochloride	19	5.1	5.1
Amantadine	15	5.1	5.1
Meclizine	15	4.8	4.8
Armodafinil	19	4.7	4.7
Nebivolol	14	4.6	4.6
Amitriptyline Hydrochloride	15	4.5	4.5
Duloxetine	58	4.4	4.4
Tizanidine	20	4.4	4.4
Lidicaine	40	4.3	4.3
Burn Relief	40	4.3	4.3
Misoprostol	8	4.3	4.3
Lidocaine Hydrochloride And Epinephrine	40	4.3	4.3
Candesartan	29	4.3	4.3
Clotrimazole	10	4.3	4.3
Lidocaine, Menthol	40	4.3	4.3
Rizatriptan Benzoate	8	4.1	4.1
Onabotulinumtoxina	60	4.1	4.1
Drs. Clotrimazole	9	4.1	4.1
Family Wellness Clotrimazole	9	4.1	4.1
Clotrimazole Topical	9	4.1	4.1
Magnesium	63	4.1	4.1
Duloxetine Hydrochloride	140	4.0	4.0
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	23	4.0	4.0
Topiramate	68	3.9	3.9
Ixazomib	21	3.8	3.8
Phenytoin	15	3.8	3.8
Oxybutynin	21	3.8	3.8
Extended Phenytoin Sodium	12	3.8	3.8
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	25	3.7	3.7
Sumatriptan	26	3.6	3.6
Lacosamide	25	3.5	3.5
Galcanezumab-Gnlm	21	3.5	3.5
Fulvestrant	22	3.5	3.5
Lovastatin	17	3.5	3.5
Thyroid, Porcine	7	3.4	3.4
Sumatriptan Succinate	16	3.3	3.3
Amlodipine Besylate And Valsartan	7	3.3	3.3
Rimegepant Sulfate	8	3.3	3.3
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	26	3.3	3.3
Micafungin Sodium	5	3.1	3.1
Emtricitabine And Tenofovir Alafenamide	6	2.8	2.8
Naltrexone	15	2.6	2.6
Diclofenac Potassium, Film Coated	4	2.5	2.5
Diclofenac Potassium Tablets	4	2.5	2.5
Vortioxetine	8	2.5	2.5
Methadone Hydrochloride	5	2.4	2.4
Erenumab-Aooe	23	2.2	2.2
Cenegermin-Bkbj	5	2.2	2.2
Sodium Oxybate	25	2.0	2.0
Diclofenac Potassium	4	1.9	1.9
Fremanezumab-Vfrm	4	1.8	1.8
Apalutamide	4	1.8	1.8
Tapentadol Hydrochloride	11	1.7	1.7
Botulinum Toxin Type A	4	1.7	1.7
Esketamine Hydrochloride	4	1.2	1.2
Hydrocodone Bitartrate	9	1.1	1.1
Pirfenidone	7	0.9	0.9
Pomalidomide	15	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.