Reaction

Hypertonic Bladder reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,841 reports · 119 co-occurring drugs

As of the last recalculation, Hypertonic Bladder appears in 2,841 FAERS reports alongside 119 co-occurring drug terms. The strongest observed disproportionality signal is DOXEPIN HYDROCHLORIDE (PRR 55.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Doxepin Hydrochloride	93	55.7	56.2
Rabeprazole	133	46.1	46.4
Fesoterodine Fumarate	65	45.0	45.2
Tolterodine Tartrate	47	39.0	39.2
Siponimod	44	36.7	36.9
Mirabegron	174	35.0	35.2
Vibegron	36	33.3	33.5
Pramipexole	64	31.3	31.4
Rosuvastatin Calcium	102	27.5	27.6
Rabeprazole Sodium	98	27.2	27.3
Oxybutynin	97	25.1	25.2
Calcium, Magnesium, Potassium, And Sodium Oxybates	22	18.9	18.9
Oxybutynin Chloride	21	17.7	17.7
Dalfampridine	136	14.5	14.6
Baclofen	158	14.2	14.2
Alendronate Sodium	183	14.1	14.2
Biotin	56	13.4	13.4
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	53	13.0	13.1
Dutasteride	14	12.7	12.7
Thiamine Hydrochloride	21	12.4	12.5
Terazosin Hydrochloride	15	12.4	12.4
Cyanocobalamin	52	11.8	11.8
Doxepin	13	9.4	9.4
Risedronate Sodium	39	9.3	9.3
Modafinil	39	9.0	9.0
Octreotide Acetate	37	9.0	9.0
Temazepam	44	8.7	8.7
Sodium Oxybate	76	8.7	8.7
Armodafinil	24	8.4	8.4
Methocarbamol Tablets	19	8.4	8.4
Tretinoin	9	8.1	8.2
Methocarbamol	25	8.1	8.1
Felodipine Extended-Release Tablets	12	7.7	7.8
Felodipine	12	7.7	7.8
Dimethyl Fumarate	123	7.6	7.6
Losartan Potassium And Hydrochlorothiazide	12	7.6	7.6
Calcium	146	7.5	7.5
Azelastine	18	7.4	7.4
Fenofibrate	35	7.3	7.3
Chlorhexidine Gluconate	9	7.2	7.2
Hyoscyamine Sulfate	9	7.2	7.2
Pitavastatin Calcium	10	7.2	7.2
Amitriptyline Hydrochloride	17	7.1	7.1
Interferon Beta-1A	177	7.1	7.1
Tamsulosin Hydrochloride	19	6.9	6.9
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	32	6.7	6.7
Cyclobenzaprine Hydrochloride	8	6.5	6.5
Fexofenadine Hcl	8	6.4	6.4
Ergocalciferol	300	6.3	6.3
Estrogens, Conjugated	49	6.1	6.1
Aripiprazole Oral	34	6.1	6.1
Aripiprazole Orally Disintegrating	34	6.1	6.1
Hydroxyzine	39	6.1	6.1
Teriflunomide	37	6.1	6.1
Infliximab-Dyyb	24	6.1	6.1
Venlafaxine	58	6.0	6.0
Ocrelizumab	50	6.0	6.0
Relugolix	19	5.9	5.9
Finasteride	48	5.9	5.9
Conjugated Estrogens	46	5.9	5.9
Rizatriptan Benzoate	8	5.8	5.8
Gabapentin	263	5.7	5.7
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	32	5.7	5.7
Amlodipine Besylate	110	5.7	5.7
Meclizine Hydrochloride	15	5.6	5.6
Lithium Carbonate	13	5.6	5.6
Vilazodone Hydrochloride	7	5.6	5.6
Eszopiclone	19	5.5	5.5
Nitrofurantoin	12	5.3	5.4
Buspirone Hydrochloride	8	5.3	5.3
Nitrofurantoin (Monohydrate/Macrocrystals)	12	5.3	5.3
Amantadine	11	5.2	5.2
Bupropion	31	5.1	5.1
Methylphenidate Hydrochloride	41	5.1	5.1
Fluoxetine Hydrochloride	87	5.1	5.1
Citalopram Hydrobromide	73	5.1	5.1
Paliperidone	16	5.0	5.1
Interferon Beta-1B	13	5.0	5.0
Bisoprolol Fumarate	90	5.0	5.0
Fingolimod Hcl	57	4.9	4.9
Bicalutamide	10	4.8	4.8
Guanfacine	5	4.7	4.7
Quinapril Hydrochloride	5	4.6	4.7
Tizanidine	15	4.6	4.6
Methylphenidate	18	4.6	4.6
Raloxifene Hydrochloride	9	4.5	4.5
Umeclidinium Bromide And Vilanterol Trifenatate	10	4.4	4.4
Fexofenadine Hydrochloride	13	4.4	4.4
Rasagiline Mesylate	6	4.0	4.0
Onabotulinumtoxina	41	3.9	3.9
Bupivacaine	5	3.9	3.9
Peginterferon Beta-1A	7	3.9	3.9
Amikacin	9	3.9	3.9
Donepezil Hydrochloride	19	3.8	3.8
Carbidopa And Levodopa	24	3.7	3.7
Dofetilide	5	3.5	3.5
Acetaminophen, Aspirin (Nsaid) And Caffeine	8	3.5	3.5
Suvorexant	6	3.4	3.4
Acetaminophen, Aspirin, And Caffeine	9	3.1	3.1
Glatiramer Acetate	25	3.1	3.1
Diroximel Fumarate	5	3.1	3.1
Avapritinib	5	3.0	3.0
Botulinum Toxin Type A	5	3.0	3.0
Loratadine And Pseudoephedrine Sulfate	3	2.8	2.8
Ravulizumab	5	2.7	2.7
Ofatumumab	12	2.7	2.7
Natalizumab	64	2.6	2.6
Leuprolide Acetate	27	2.6	2.6
Cariprazine	3	2.4	2.4
Rimegepant Sulfate	4	2.3	2.3
Bimatoprost	9	2.3	2.3
Conjugated Estrogens And Medroxyprogesterone Acetate	7	2.2	2.2
Enzalutamide	15	1.9	1.9
Abaloparatide	6	1.5	1.5
Droxidopa	4	1.4	1.4
Guselkumab	6	1.2	1.2
Pimavanserin Tartrate	8	1.1	1.1
Valbenazine	3	0.9	0.9
Copper	5	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.