OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Substance-Induced Psychotic Disorder reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,183 reports · 68 co-occurring drugs

As of the last recalculation, Substance-Induced Psychotic Disorder appears in 2,183 FAERS reports alongside 68 co-occurring drug terms. The strongest observed disproportionality signal is METHADONE HYDROCHLORIDE (PRR 23.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Methadone Hydrochloride2623.223.2
Amphetamine1820.920.9
Haloperidol Lactate5220.520.5
Haloperidol5120.520.5
Aripiprazole Oral7718.418.4
Aripiprazole Orally Disintegrating7718.418.4
Methylprednisolone Acetate1518.018.0
Levetiracetam In Sodium Chloride11615.015.0
Levetiracetam Oral11615.015.0
Levetiracetam Injection11615.015.0
Isoniazid2514.914.9
Prednisolone23914.114.1
Prednisolone Oral23914.114.1
Prednisolone Oral Solution23914.114.1
Diphenhydramine Hydrochloride Capsule, Liquid Filled3013.613.6
Methadone5412.312.3
Pyrazinamide1212.212.3
Methylprednisolone Sodium Succinate5210.910.9
Valproic Acid3510.710.8
Olanzapine11210.410.4
Metronidazole Topical5010.210.2
Hydrocortisone Sodium Succinate1010.210.2
Risperidone13410.210.2
Methylprednisolone1369.99.9
Methylphenidate Hydrochloride609.99.9
Levetiracetam1269.59.5
Selinexor88.88.8
Methylphenidate268.78.7
Dexamethasone Sodium Phosphate98.58.5
Aripiprazole1028.38.3
Metronidazole548.28.2
Bupivacaine88.28.2
Lorazepam1458.28.2
Lithium218.08.0
Lithium Bromatum218.08.0
Paliperidone197.87.8
Calcium, Magnesium, Potassium, And Sodium Oxybates77.87.8
Rasagiline Mesylate97.77.7
Tranexamic Acid77.57.5
Paroxetine Hydrochloride Hemihydrate267.57.5
Paroxetine267.47.4
Dexamethasone 1.5 Mg2057.37.3
Dexamethasone2057.27.2
Fluoxetine497.17.1
Clarithromycin246.76.7
Tacrolimus Ointment 0.1%796.26.2
Tacrolimus Extended-Release Capsules796.26.2
Amantadine106.26.2
Desvenlafaxine Succinate165.75.7
Clobazam135.15.1
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate225.15.1
Romiplostim85.15.1
Guanfacine44.94.9
Axicabtagene Ciloleucel54.84.8
Levodopa64.74.7
Olaparib104.64.6
Irinotecan Hydrochloride64.54.5
Suvorexant53.73.7
Ethyl Alcohol103.53.5
Naltrexone Hydrochloride And Bupropion Hydrochloride33.43.4
Buprenorphine293.03.0
Crizotinib43.03.0
Alcohol123.03.0
Brexpiprazole52.92.9
Remdesivir42.92.9
Paliperidone Palmitate92.72.7
Tapentadol Hydrochloride61.71.7
Esketamine Hydrochloride31.61.6

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.