Reaction

Osteoporotic Fracture reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,901 reports · 60 co-occurring drugs

As of the last recalculation, Osteoporotic Fracture appears in 1,901 FAERS reports alongside 60 co-occurring drug terms. The strongest observed disproportionality signal is RALOXIFENE HYDROCHLORIDE (PRR 44.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Raloxifene Hydrochloride	58	44.8	45.0
Emtricitabine And Tenofovir Disoproxil Fumarate	110	28.0	28.0
Naproxen Sodium Tablet, Coated	32	26.3	26.4
Naproxen Sodium, Coated Tablets	32	26.3	26.4
Naproxen Sodium 220Mg	32	26.3	26.3
Tenofovir Disoproxil Fumarate	75	25.8	25.9
Emtricitabine And Tenofovir Alafenamide	26	25.4	25.5
Raltegravir	36	24.3	24.4
Adalimumab-Fkjp	90	22.3	22.3
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	34	20.9	20.9
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	18	19.8	19.8
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	16	19.6	19.6
Romosozumab-Aqqg	24	19.6	19.6
Adalimumab-Aaty	81	19.5	19.6
Tenofovir Disoproxil Fumarate Tablets	15	19.2	19.2
Lopinavir And Ritonavir	23	18.8	18.8
Trimethoprim	20	18.8	18.8
Adalimumab-Adaz	81	17.5	17.5
Baricitinib	15	17.2	17.2
Zidovudine	20	16.5	16.6
Denosumab	260	16.1	16.1
Risedronate Sodium	41	14.7	14.8
Tocilizumab	139	14.3	14.3
Hydroxychloroquine	88	13.5	13.5
Nevirapine	10	12.2	12.2
Leflunomide	110	12.2	12.2
Ritonavir	31	11.8	11.8
Tofacitinib Citrate	14	11.8	11.8
Acetaminophen And Codeine	13	11.8	11.8
Canakinumab	11	11.2	11.2
Abatacept	132	11.1	11.2
Lamivudine	30	10.8	10.8
Alendronate Sodium Tablet	18	10.7	10.7
Darunavir	14	10.2	10.2
Hydroxychloroquine Sulfate	80	10.0	10.0
Atazanavir	13	10.0	10.0
Bleomycin Sulfate	9	9.6	9.6
Prednisolone	145	9.4	9.4
Prednisolone Oral	145	9.4	9.4
Prednisolone Oral Solution	145	9.4	9.4
Itraconazole	10	9.4	9.4
Desoximetasone	16	9.3	9.3
Naproxen	62	8.9	8.9
Loperamide Hydrochloride Oral	8	8.6	8.6
Lamivudine Oral	19	8.3	8.3
Efavirenz	8	7.9	7.9
Zoledronic Acid	28	7.7	7.7
Ifosfamide	15	7.7	7.7
Teriparatide	73	7.3	7.3
Anakinra	11	7.3	7.3
Sulfasalazine	48	6.9	6.9
Loperamide Hcl	8	6.8	6.8
Polatuzumab Vedotin	6	6.7	6.8
Medroxyprogesterone Acetate	28	6.2	6.2
Dolutegravir Sodium	5	6.1	6.1
Thiotepa	5	5.7	5.7
Abiraterone	7	5.6	5.6
Tofacitinib	83	5.1	5.1
Apalutamide	4	3.7	3.7
Abiraterone Acetate	10	2.7	2.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.