Reaction

Which drugs are most reported with Breast tenderness?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,467 reports · 71 co-occurring drugs

As of the last recalculation, Breast Tenderness appears in 7,467 FAERS reports alongside 71 co-occurring drug terms. The strongest observed disproportionality signal is LEVONORGESTREL (PRR 49.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Levonorgestrel	2,421	49.1	49.7
Estradiol	453	15.5	15.6
Progesterone	115	14.2	14.3
Etonogestrel And Ethinyl Estradiol	104	13.2	13.3
Drospirenone And Ethinyl Estradiol	163	10.5	10.5
Etonogestrel	160	9.5	9.6
Estradiol Gel 0.1%	146	9.2	9.2
Estradiol Transdermal	146	9.2	9.2
Conjugated Estrogens And Medroxyprogesterone Acetate	65	7.7	7.8
Estrogens, Conjugated	133	6.3	6.4
Conjugated Estrogens	129	6.3	6.3
Dutasteride	16	5.5	5.5
Bicalutamide	29	5.3	5.3
Medroxyprogesterone Acetate	92	5.2	5.2
Paliperidone Palmitate	56	4.9	4.9
Finasteride	103	4.8	4.8
Raloxifene Hydrochloride	25	4.8	4.8
Leuprolide Acetate	130	4.7	4.7
Copper	51	3.3	3.3
Ezetimibe And Simvastatin	16	2.9	2.9
Multivitamin	52	2.9	2.9
Paliperidone	23	2.8	2.8
Goserelin	13	2.7	2.7
Spironolactone	131	2.6	2.6
Misoprostol	9	2.6	2.6
Enzalutamide	53	2.5	2.5
Rabeprazole Sodium	24	2.5	2.5
Anastrozole	32	2.4	2.4
Vilazodone Hydrochloride	8	2.4	2.4
Amlodipine Besylate And Benazepril Hydrochloride	8	2.4	2.4
Eplerenone	11	2.4	2.4
Vitamin E	26	2.3	2.3
Testosterone	19	2.3	2.3
Psyllium Husk	8	2.3	2.3
Liothyronine Sodium	7	2.2	2.2
Biotin	25	2.2	2.2
Fexofenadine	13	2.2	2.2
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	27	2.1	2.1
Ropinirole	11	2.0	2.0
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	29	2.0	2.0
Risperidone	91	1.9	1.9
Tamsulosin Hydrochloride	14	1.9	1.9
Apalutamide	8	1.9	1.9
Thyroid, Porcine	7	1.8	1.8
Bupropion Hydrochloride	62	1.8	1.8
Brexpiprazole	10	1.7	1.7
Icosapent Ethyl	5	1.6	1.6
Letrozole Tablets	28	1.6	1.6
Teriparatide	64	1.6	1.6
Cariprazine	5	1.5	1.5
Relugolix	12	1.4	1.4
Desvenlafaxine Succinate	13	1.3	1.3
Orlistat	12	1.3	1.3
Asenapine Maleate	4	1.3	1.3
Lisdexamfetamine Dimesylate	15	1.3	1.3
Lurasidone Hydrochloride	9	1.2	1.2
Abaloparatide	12	1.1	1.1
Elexacaftor, Tezacaftor, And Ivacaftor	5	1.1	1.1
Sofosbuvir	7	1.0	1.0
Fremanezumab-Vfrm	4	1.0	1.0
Naproxen Sodium Tablet	18	0.9	0.9
Galcanezumab-Gnlm	10	0.9	0.9
Minoxidil Foam 5% (Womens)	9	0.8	0.8
Ofatumumab	9	0.8	0.8
Varenicline Tartrate	20	0.7	0.7
Minoxidil	10	0.6	0.6
Tapentadol Hydrochloride	7	0.6	0.6
Erenumab-Aooe	11	0.6	0.6
Lifitegrast	3	0.5	0.5
Apremilast	24	0.5	0.5
Cinacalcet Hydrochloride	6	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.