Reaction

Kounis Syndrome reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,231 reports · 98 co-occurring drugs

As of the last recalculation, Kounis Syndrome appears in 2,231 FAERS reports alongside 98 co-occurring drug terms. The strongest observed disproportionality signal is ROCURONIUM BROMIDE (PRR 74.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Rocuronium Bromide	90	74.2	74.8
Cefazolin	67	70.6	71.1
Cefazolin Sodium	77	61.7	62.1
Sevoflurane	32	36.4	36.6
Ceftriaxone Sodium	130	33.5	33.6
Adrenalinum	126	30.0	30.1
Daptomycin	29	29.7	29.8
Ceftriaxone	98	29.1	29.2
Propofol	108	28.9	29.0
Diclofenac Potassium, Film Coated	25	28.0	28.1
Diclofenac Potassium Tablets	25	28.0	28.1
Piperacillin And Tazobactam	36	26.7	26.7
Midazolam	68	25.9	26.0
Piperacillin Sodium,Tazobactam Sodium	69	25.0	25.1
Midazolam Hydrochloride	69	24.6	24.7
Cefuroxime	29	24.0	24.0
Diclofenac Potassium	25	21.8	21.9
Lidicaine	108	21.6	21.6
Burn Relief	108	21.6	21.6
Lidocaine Hydrochloride And Epinephrine	108	21.6	21.6
Lidocaine Hydrochloride	131	21.5	21.5
Lidocaine, Menthol	108	21.3	21.3
Bupivacaine	21	21.2	21.2
Lidocaine Hydrochloride And Epinephrine Bitartrate	111	20.4	20.4
Epinephrine	134	20.2	20.3
Phenobarbital	31	20.2	20.3
Lidocaine 4%	109	19.6	19.6
Iohexol	16	18.1	18.2
Lidocaine	108	18.1	18.1
Diclofenac	156	18.1	18.1
Vancomycin Hydrochloride	120	17.9	17.9
Piperacillin Sodium And Tazobactam Sodium	36	17.4	17.4
Metronidazole Topical	74	15.0	15.0
Atropine	12	13.6	13.6
Atropine Sulfate	15	13.0	13.1
Clopidogrel Bisulfate	127	12.2	12.2
Vancomycin	72	12.0	12.0
Methimazole	10	11.9	11.9
Diclofenac Sodium 1%	44	11.7	11.7
Diclofenac Sodium Topical	44	11.7	11.7
Diclofenac Sodium Topical Gel, 1%	44	11.7	11.7
Metronidazole	76	11.5	11.5
Diclofenac Sodium	160	10.6	10.6
Norepinephrine	12	10.5	10.5
Fentanyl	105	10.4	10.4
Clindamycin	31	10.3	10.3
Amoxicillin And Clavulanate Potassium	29	10.1	10.1
Norepinephrine Bitartrate	15	9.8	9.8
Captopril	10	9.7	9.8
Clindamycin Phosphate	33	9.3	9.3
Anti-Itch	65	9.3	9.3
Anti-Pruritic	65	9.3	9.3
Antipruritic (Anti-Itch)	65	9.3	9.3
Cool Relief Gel With Aloe	65	9.3	9.3
Drs. Hydrocortisone	65	9.3	9.3
Hydrocortisone Continuous Spray	65	9.3	9.3
Hydrocortisone Spray	65	9.3	9.3
Anti-Itch Cream	65	9.3	9.3
Hydrocortisone Lotion	65	9.3	9.3
Hydrocortisone Cream 1%	65	9.3	9.3
Hydrocortisone Cream 1/2%	65	9.3	9.3
Hydrocortisone 1%	65	9.3	9.3
Hydrocortisone Cream	65	9.2	9.2
Rizatriptan Benzoate	10	9.2	9.2
Amoxicillin	72	9.1	9.1
Hydrocortisone Acetate	65	8.6	8.6
Methylphenidate	26	8.5	8.5
Levofloxacin	53	8.4	8.4
Levofloxacin In 5% Dextrose	53	8.4	8.4
Amiodarone Hydrochloride	10	8.4	8.4
Ibuprofen Oral	165	8.3	8.3
Nebivolol	14	8.2	8.3
Methylphenidate Hydrochloride	51	8.2	8.2
Ibuprofen Capsule	163	8.1	8.2
Ibuprofen Tablet, Film Coated	163	8.1	8.2
Ibupfrofen	163	8.1	8.2
Ibuprofen Tablets Usp, 200Mg	163	8.1	8.2
Ibuprofen Capsules 200 Mg	163	8.1	8.1
Ibuprofen 200 Mg	163	8.1	8.1
Ibuprofen 200Mg	163	8.1	8.1
Paclitaxel (Aibumin-Bound)	64	7.4	7.5
Isosorbide Mononitrate	16	7.2	7.2
Dextrose	10	7.1	7.1
Dextrose Monohydrate	10	7.0	7.0
Isosorbide Dinitrate	14	6.7	6.7
Paclitaxel	64	6.2	6.2
Clopidogrel	122	6.0	6.0
Naproxen Sodium Tablet, Coated	8	5.5	5.5
Naproxen Sodium, Coated Tablets	8	5.5	5.5
Naproxen Sodium 220Mg	8	5.5	5.5
Granisetron	5	4.5	4.5
Levetiracetam In Sodium Chloride	35	4.3	4.3
Levetiracetam Oral	35	4.3	4.3
Levetiracetam Injection	35	4.3	4.3
Fentanyl Citrate	8	4.2	4.2
Carboplatin	50	3.7	3.7
Remdesivir	5	3.5	3.5
Copper	11	2.4	2.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.