Reaction

Large Intestinal Ulcer reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,667 reports · 83 co-occurring drugs

As of the last recalculation, Large Intestinal Ulcer appears in 2,667 FAERS reports alongside 83 co-occurring drug terms. The strongest observed disproportionality signal is ENCORAFENIB (PRR 29.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Encorafenib	37	29.6	29.7
Sevelamer Carbonate	30	20.6	20.6
Vedolizumab	191	18.6	18.6
Ganciclovir	21	16.1	16.2
Ganciclovir Sodium	21	15.6	15.6
Valganciclovir Hydrochloride Powder,	24	15.5	15.5
Mesalamine	106	15.3	15.3
Valganciclovir	36	15.1	15.1
Valganciclovir Hydrochloride	36	15.1	15.1
Indomethacin	21	12.5	12.5
Infliximab-Dyyb	45	12.2	12.2
Diclofenac	119	11.2	11.3
Mycophenilic Acid	29	11.0	11.0
Bisacodyl Suppositories	18	10.9	10.9
Biscodyl	18	10.8	10.8
Bisacodyl	19	10.6	10.6
Azathioprine	115	10.6	10.6
Diclofenac Sodium 1%	46	10.2	10.2
Diclofenac Sodium Topical	46	10.2	10.2
Diclofenac Sodium Topical Gel, 1%	46	10.2	10.2
Olmesartan Medoxomil	42	9.2	9.3
Adalimumab-Fkjp	50	8.6	8.6
Adalimumab-Aaty	50	8.4	8.4
Mercaptopurine	18	8.1	8.2
Diclofenac Sodium	145	7.9	7.9
Mycophenolic Acid	32	7.9	7.9
Loperamide Hydrochloride And Dimethicone	32	7.9	7.9
Anti-Itch	65	7.7	7.7
Anti-Pruritic	65	7.7	7.7
Antipruritic (Anti-Itch)	65	7.7	7.7
Cool Relief Gel With Aloe	65	7.7	7.7
Drs. Hydrocortisone	65	7.7	7.7
Hydrocortisone Continuous Spray	65	7.7	7.7
Hydrocortisone Spray	65	7.7	7.7
Anti-Itch Cream	65	7.7	7.7
Hydrocortisone Lotion	65	7.7	7.7
Hydrocortisone Cream 1%	65	7.7	7.7
Hydrocortisone Cream 1/2%	65	7.7	7.7
Hydrocortisone 1%	65	7.7	7.7
Hydrocortisone Cream	65	7.7	7.7
Adalimumab-Adaz	51	7.7	7.7
Sirolimus	13	7.6	7.6
Tacrolimus	143	7.5	7.5
Hydrocortisone Acetate	67	7.4	7.4
Tacrolimus Ointment 0.1%	112	7.3	7.3
Tacrolimus Extended-Release Capsules	112	7.3	7.3
Everolimus Tablets	15	7.0	7.0
Loperamide Hydrochloride	39	6.9	6.9
Anti-Thymocyte Globulin (Rabbit)	7	6.8	6.8
Midazolam Hydrochloride	23	6.7	6.7
Cholestyramine	10	6.5	6.5
Remdesivir	11	6.5	6.5
Prednisolone	142	6.4	6.4
Prednisolone Oral	142	6.4	6.4
Prednisolone Oral Solution	142	6.4	6.4
Budesonide	47	6.3	6.3
Diphenoxylate Hydrochloride And Atropine Sulfate	11	6.3	6.3
Infliximab	166	6.3	6.3
Loperamide Hydrochloride Oral	8	6.1	6.1
Cefepime	11	6.0	6.0
Mycophenolate Mofetil	101	6.0	6.0
Mycophenolate Mofetil Hydrochloride	101	6.0	6.0
Loperamide Hcl	9	5.5	5.5
Cefepime Hydrochloride	11	5.3	5.3
Piperacillin Sodium,Tazobactam Sodium	18	5.3	5.3
Gefitinib	6	5.2	5.2
Instalax Polyethylene Glycol 3350	8	5.0	5.0
Adalimumab	401	5.0	5.0
Polyethylene Glycol 400	8	4.9	4.9
Ustekinumab	63	4.9	4.9
Polatuzumab Vedotin	6	4.8	4.8
Bendamustine Hcl	9	4.5	4.5
Upadacitinib	46	4.5	4.5
Tofacitinib Citrate	7	4.2	4.2
Isotretinoin	25	4.0	4.0
Deferasirox	13	3.8	3.8
Dasatinib	18	3.8	3.8
Risankizumab-Rzaa	34	3.3	3.3
Cetuximab	13	3.2	3.2
Fentanyl Citrate	7	3.1	3.1
Ipilimumab	14	2.5	2.5
Trifluridine And Tipiracil	3	2.2	2.2
Lenvatinib	9	2.1	2.1

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.