Reaction

Periodontitis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,114 reports · 62 co-occurring drugs

As of the last recalculation, Periodontitis appears in 2,114 FAERS reports alongside 62 co-occurring drug terms. The strongest observed disproportionality signal is ALENDRONATE SODIUM (PRR 30.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Alendronate Sodium	271	30.2	30.3
Chlorhexidine Gluconate	25	27.2	27.3
Febuxostat Tablets 40 Mg	23	22.5	22.6
Febuxostat Tablets 80 Mg	23	22.5	22.6
Fondaparinux Sodium	17	20.8	20.9
Granisetron Hydrochloride	21	20.0	20.0
Risedronate Sodium	59	19.2	19.2
Dexamethasone Sodium Phosphate	18	17.6	17.6
Buprenorphine Hydrochloride, Naloxone Hydrochloride	42	17.5	17.5
Goserelin	23	17.0	17.1
Exemestane	35	16.3	16.4
Zoledronic Acid	61	15.4	15.4
Bicalutamide	22	14.4	14.4
Febuxostat	23	13.6	13.7
Granisetron	13	12.3	12.3
Amitriptyline Hydrochloride	21	11.9	11.9
Meperidine Hydrochloride	11	11.8	11.8
Letrozole	68	11.2	11.2
Insulin Glargine-Yfgn	24	10.9	10.9
Fulvestrant	36	10.9	10.9
Anastrozole	39	10.6	10.6
Gemfibrozil	16	10.5	10.5
Doxepin Hydrochloride	13	10.2	10.2
Nebivolol	15	9.3	9.3
Filgrastim	34	9.0	9.0
Denosumab	172	9.0	9.0
Ferrous Sulfate	45	9.0	9.0
Ribociclib	28	8.8	8.8
Doxepin	9	8.8	8.8
Thalidomide	32	8.7	8.7
Cefazolin Sodium	10	8.2	8.2
Epoetin Alfa	9	7.5	7.5
Cefepime Hydrochloride	12	7.4	7.4
Romosozumab-Aqqg	10	7.3	7.3
Colchicine	19	7.2	7.2
Amoxicillin	54	7.1	7.1
Nifedipine	33	7.0	7.0
Cefepime	10	6.9	6.9
Naproxen Sodium Tablet, Coated	9	6.6	6.6
Naproxen Sodium, Coated Tablets	9	6.6	6.6
Naproxen Sodium 220Mg	9	6.6	6.6
Capecitabine	58	6.4	6.4
Baricitinib	6	6.1	6.1
Paclitaxel (Aibumin-Bound)	50	6.1	6.1
Raloxifene Hydrochloride	9	6.1	6.1
Melphalan Hydrochloride	15	5.9	5.9
Bevacizumab	72	5.9	5.9
Letrozole Tablets	28	5.8	5.8
Pitavastatin Calcium	6	5.8	5.8
Bortezomib	51	5.7	5.7
Cortisone Acetate	7	5.6	5.6
Paclitaxel	55	5.6	5.6
Trastuzumab	34	4.9	4.9
Ado-Trastuzumab Emtansine	4	4.7	4.7
Darbepoetin Alfa	25	4.6	4.6
Brinzolamide	4	4.5	4.5
Nicotine Polacrilex	15	3.9	3.9
Azacitidine	11	3.7	3.7
Alpelisib	3	3.4	3.4
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	3	2.9	2.9
Aflibercept	8	2.5	2.5
Ranitidine Hydrochloride	11	2.0	2.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.