Reaction

Suicidal Behaviour reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,128 reports · 113 co-occurring drugs

As of the last recalculation, Suicidal Behaviour appears in 4,128 FAERS reports alongside 113 co-occurring drug terms. The strongest observed disproportionality signal is VARENICLINE TARTRATE (PRR 23.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Varenicline Tartrate	339	23.2	23.3
Brexpiprazole	41	12.6	12.6
Ziprasidone Mesylate	35	12.5	12.5
Fluoxetine	159	12.5	12.5
Zonisamide	35	12.0	12.0
Fluoxetine Hydrochloride	269	11.3	11.3
Atomoxetine Hydrochloride	51	10.9	10.9
Ziprasidone	36	10.4	10.4
Quetiapine	335	9.5	9.5
Methylphenidate Hydrochloride	106	9.2	9.2
Guanfacine	14	9.0	9.0
Desvenlafaxine Succinate	47	8.9	8.9
Ethyl Alcohol	47	8.8	8.8
Vilazodone Hydrochloride	16	8.8	8.8
Diazepam Oral Solution (Concentrate)	146	8.5	8.5
Diazepam Oral	146	8.5	8.5
Sertraline	183	8.2	8.2
Asenapine Maleate	14	8.2	8.2
Lisdexamfetamine Dimesylate	51	7.9	7.9
Olanzapine Pamoate	61	7.6	7.6
Diazepam	175	7.5	7.5
Lurasidone Hydrochloride	31	7.5	7.5
Isopropyl Alcohol	48	7.2	7.2
Sertraline Hydrochloride	158	6.9	7.0
Lamotrigine	175	6.9	7.0
Venlafaxine Hydrochloride	175	6.9	6.9
Progesterone	31	6.9	6.9
Clobazam	33	6.9	6.9
Lithium Carbonate	23	6.9	6.9
Hydrocodone Bitartrate And Acetaminophen	74	6.7	6.7
Alcohol	51	6.7	6.7
Lamotirigine	93	6.7	6.7
Lamotrigine Extended-Release	93	6.7	6.7
Lamotrigine Chewable Dispersible	93	6.7	6.7
Lithium	33	6.6	6.7
Lithium Bromatum	33	6.6	6.7
Methylphenidate	37	6.5	6.5
Mirtazapine	115	6.5	6.5
Aripiprazole	150	6.4	6.4
Paroxetine	42	6.3	6.3
Vortioxetine	21	6.3	6.3
Aripiprazole Oral	50	6.2	6.2
Aripiprazole Orally Disintegrating	50	6.2	6.2
Paroxetine Hydrochloride Hemihydrate	40	6.1	6.1
Divalproex Sodium	54	5.9	5.9
Olanzapine	120	5.8	5.8
Valproic Acid	35	5.6	5.6
Levetiracetam In Sodium Chloride	85	5.6	5.6
Levetiracetam Oral	85	5.6	5.6
Levetiracetam Injection	85	5.6	5.6
Paroxetine Hydrochloride	99	5.6	5.6
Duloxetine Hydrochloride	200	5.6	5.6
Venlafaxine	77	5.5	5.5
Escitalopram	147	5.4	5.4
Propranolol Hydrochloride	76	5.4	5.4
Citalopram	140	5.3	5.3
Citalopram Hydrobromide	110	5.3	5.3
Escitslopram	60	5.3	5.3
Clonazepam	160	5.2	5.2
Quetiapine Fumarate	30	5.2	5.2
Oxcarbazepine	33	5.2	5.2
Montelukast	83	5.1	5.1
Levetiracetam	130	5.0	5.0
Bupropion Hydrochloride	96	5.0	5.0
Melatonin	53	5.0	5.0
Escitalopram Oxalate	70	4.9	4.9
Montelukast Sodium	115	4.9	4.9
Zolpidem Tartrate	127	4.9	4.9
Risperidone	120	4.7	4.7
Brivaracetam	8	4.5	4.5
Hydroxyzine	41	4.4	4.4
Topiramate	79	4.3	4.3
Lorazepam	150	4.3	4.3
Amphetamine	7	4.3	4.3
Sumatriptan Succinate	21	4.2	4.2
Buprenorphine Hydrochloride, Naloxone Hydrochloride	20	4.2	4.2
Isotretinoin	39	4.0	4.0
Clozapine	95	3.9	3.9
Cariprazine	7	3.8	3.8
Esketamine Hydrochloride	13	3.7	3.7
Sumatriptan	27	3.6	3.6
Haloperidol	17	3.5	3.5
Suvorexant	9	3.5	3.5
Oxycodone Hydrochloride	147	3.5	3.5
Haloperidol Lactate	17	3.5	3.5
Alprazolam	138	3.5	3.5
Finasteride	41	3.5	3.5
Hydromorphone Hydrochloride	59	3.3	3.3
Nicotine	26	3.3	3.3
Pregabalin	162	3.1	3.1
Lacosamide	22	3.0	3.0
Methadone	24	2.8	2.8
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	23	2.8	2.8
Fremanezumab-Vfrm	6	2.6	2.6
Derma Foam Excel Hand Sanitizer	4	2.5	2.5
Ethanol	4	2.5	2.5
Levodopa	6	2.5	2.5
Naltrexone	15	2.5	2.5
Interferon Beta-1A	86	2.3	2.3
Paliperidone	10	2.2	2.2
Oseltamivir Phosphate	10	2.1	2.1
Paliperidone Palmitate	13	2.0	2.0
Pegvaliase-Pqpz	3	1.8	1.8
Cenobamate	3	1.8	1.8
Drospirenone And Ethinyl Estradiol	13	1.5	1.5
Bimekizumab	6	1.4	1.4
Hydrocodone Bitartrate	12	1.4	1.4
Buprenorphine	24	1.3	1.3
Minoxidil Foam 5% (Womens)	8	1.2	1.2
Valbenazine	5	1.0	1.0
Minoxidil	8	0.9	0.9
Pimavanserin Tartrate	8	0.7	0.7
Etonogestrel	6	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.