Reaction

Therapeutic Product Effect Delayed reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,450 reports · 109 co-occurring drugs

As of the last recalculation, Therapeutic Product Effect Delayed appears in 4,450 FAERS reports alongside 109 co-occurring drug terms. The strongest observed disproportionality signal is RIMEGEPANT SULFATE (PRR 49.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Rimegepant Sulfate	131	49.8	50.3
Levodopa	80	31.5	31.7
Instalax Polyethylene Glycol 3350	54	20.6	20.7
Polyethylene Glycol 400	54	20.1	20.2
Docosanol	58	18.7	18.8
Vibegron	30	17.6	17.7
Glycerin, Lidocaine	45	15.2	15.2
Calcium, Magnesium, Potassium, And Sodium Oxybates	27	14.7	14.8
Eptinezumab-Jjmr	26	13.4	13.5
Loperamide Hydrochloride Oral	25	11.5	11.5
Carbidopa And Levodopa	99	10.0	10.0
Loperamide Hcl	25	9.1	9.2
Pimavanserin Tartrate	104	9.0	9.0
Rasagiline Mesylate	21	8.9	8.9
Polyethylene Glycol 3350	166	8.4	8.4
Suvorexant	22	8.0	8.0
Erenumab-Aooe	90	7.8	7.8
Pramipexole	25	7.7	7.7
Infliximab-Dyyb	47	7.6	7.6
Rotigotine	22	7.1	7.2
Drs. Clotrimazole	17	6.9	6.9
Family Wellness Clotrimazole	17	6.9	6.9
Clotrimazole Topical	17	6.9	6.9
Ropinirole	22	6.7	6.7
Clotrimazole	17	6.5	6.5
Atropine Sulfate	14	6.1	6.1
Quinine	11	6.0	6.0
Pseudoephedrine Hydrochloride	13	5.9	5.9
Ibuprofen Tablets, Coated	53	5.9	5.9
Ibuprofen Sodium	53	5.8	5.8
Fremanezumab-Vfrm	14	5.7	5.7
Pseudoephedrine Hcl	13	5.5	5.5
Acetaminophen, Aspirin (Nsaid) And Caffeine	20	5.5	5.5
Levocetirizine Dihydrochloride	27	5.3	5.3
Acetaminophen, Aspirin, And Caffeine	23	5.1	5.1
Linaclotide	29	5.1	5.1
Bisacodyl Suppositories	14	5.1	5.1
Biscodyl	14	5.0	5.0
Secukinumab	168	5.0	5.0
Bisacodyl	15	5.0	5.0
Risankizumab-Rzaa	86	5.0	5.0
Tofacitinib	189	5.0	5.0
Crisaborole	10	4.9	4.9
Amantadine	16	4.9	4.9
Trimethoprim	12	4.8	4.8
Tranexamic Acid	9	4.7	4.7
Mupirocin	13	4.5	4.5
Mupirocin Calcium	13	4.4	4.4
Magnesium Sulfate In Water For	12	4.4	4.4
Magnesium Sulfate Heptahydrate	12	4.3	4.3
Magnesium Sulfate	12	4.3	4.3
Magnesium Hydroxide	12	4.2	4.2
Bupivacaine	8	4.0	4.0
Upadacitinib	68	3.9	3.9
Cetirizine Hydrochloride Allergy	25	3.9	3.9
Cetirizine Hydrochloride Tablets	25	3.9	3.9
Rivastigmine	15	3.7	3.7
Naproxen Sodium Tablet	41	3.6	3.6
Diclofenac Sodium	114	3.6	3.6
Insulin Aspart	50	3.6	3.6
Minoxidil Foam 5% (Womens)	25	3.6	3.6
Carboxymethylcellulose Sodium	7	3.5	3.5
Minoxidil	33	3.5	3.5
Fexofenadine Hydrochloride	16	3.5	3.5
Mesalamine	39	3.3	3.3
Methylphenidate	20	3.2	3.2
Ibuprofen And Diphenhydramine Citrate	16	3.2	3.2
Loperamide Hydrochloride	30	3.2	3.2
Ravulizumab	9	3.1	3.1
Sumatriptan Succinate	16	3.0	3.0
Desoximetasone	12	3.0	3.0
Lifitegrast	10	2.9	2.9
Sodium Oxybate	40	2.9	2.9
Lisdexamfetamine Dimesylate	20	2.8	2.8
Triamcinolone Acetonide Ointment Usp, 0.05%	14	2.8	2.8
Insulin Degludec	14	2.8	2.8
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	21	2.8	2.8
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	24	2.7	2.7
Sumatriptan	22	2.7	2.7
Dofetilide	6	2.7	2.7
Methylphenidate Hydrochloride	33	2.6	2.6
Triamcinolone Acetonide	17	2.6	2.6
Cariprazine	5	2.5	2.5
Rocuronium Bromide	6	2.4	2.4
Ruxolitinib	36	2.4	2.4
Onabotulinumtoxina	38	2.3	2.3
Fesoterodine Fumarate	5	2.2	2.2
Desvenlafaxine Succinate	12	2.1	2.1
Brivaracetam	4	2.1	2.1
Tafamidis	5	2.0	2.0
Galcanezumab-Gnlm	13	1.9	1.9
Vedolizumab	35	1.9	1.9
Botulinum Toxin Type A	5	1.9	1.9
Romosozumab-Aqqg	5	1.7	1.7
Diclofenac Potassium, Film Coated	3	1.7	1.7
Diclofenac Potassium Tablets	3	1.7	1.7
Guselkumab	12	1.6	1.6
Bimekizumab	7	1.5	1.5
Belimumab	10	1.5	1.5
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	13	1.5	1.5
Brexpiprazole	5	1.4	1.4
Certolizumab Pegol	35	1.4	1.4
Esketamine Hydrochloride	5	1.3	1.3
Apremilast	38	1.2	1.2
Valbenazine	6	1.1	1.1
Nemolizumab-Ilto	3	1.1	1.1
Ixekizumab	8	1.0	1.0
Dupilumab	102	1.0	1.0
Droxidopa	4	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.