Reaction

Drug Rash With Eosinophilia And Systemic Symptoms reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,248 reports · 90 co-occurring drugs

As of the last recalculation, Drug Rash With Eosinophilia And Systemic Symptoms appears in 3,248 FAERS reports alongside 90 co-occurring drug terms. The strongest observed disproportionality signal is RIFAMPICIN (PRR 62.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Rifampicin	96	62.6	63.2
Carbamazepine	446	49.3	49.6
Phenytoin	141	45.2	45.5
Zonisamide	78	34.6	34.8
Gentamicin	61	30.4	30.6
Gentamicin Sulfate	73	30.3	30.4
Vancomycin	219	26.0	26.1
Vancomycin Hydrochloride	233	24.3	24.4
Piperacillin And Tazobactam	41	20.8	20.9
Pyrazinamide	29	20.0	20.0
Valproate Sodium	59	18.6	18.7
Abacavir Sulfate	27	17.9	17.9
Lamotrigine	301	16.0	16.1
Piperacillin Sodium And Tazobactam Sodium	48	15.9	15.9
Atazanavir	34	15.3	15.3
Nevirapine	20	14.3	14.3
Raltegravir	35	13.7	13.7
Lamotirigine	146	13.6	13.7
Lamotrigine Extended-Release	146	13.6	13.7
Lamotrigine Chewable Dispersible	146	13.6	13.7
Isoniazid	34	13.6	13.6
Fondaparinux Sodium	16	12.7	12.8
Allopurinol	280	12.5	12.5
Ceftriaxone Sodium	73	12.5	12.5
Extended Phenytoin Sodium	32	12.4	12.4
Ceftriaxone	61	12.1	12.1
Sulfasalazine	142	12.1	12.1
Ampicillin	15	11.7	11.7
Ampicillin Sodium	15	11.7	11.7
Ritonavir	52	11.6	11.6
Amoxicillin	128	11.1	11.2
Phenobarbital	25	11.1	11.2
Valproic Acid	50	10.3	10.3
Amoxicillin And Clavulanate Potassium	42	10.0	10.0
Piperacillin Sodium,Tazobactam Sodium	41	10.0	10.0
Ketoprofen	20	9.8	9.8
Lopinavir And Ritonavir	20	9.5	9.5
Lithium Carbonate	25	9.5	9.5
Amikacin	25	9.5	9.5
Peginterferon Alfa-2A	76	9.2	9.2
Ribavirin	87	8.9	8.9
Sulfamethoxazole And Trimethoprim	106	8.3	8.3
Enoxaparin Sodium	69	7.8	7.8
Desloratadine	13	7.8	7.8
Daptomycin	11	7.7	7.7
Lamivudine	36	7.5	7.5
Enalapril Maleate	26	6.8	6.8
Metronidazole	64	6.5	6.5
Metronidazole Topical	47	6.4	6.4
Darunavir	15	6.4	6.4
Meropenem	29	5.8	5.8
Zidovudine	12	5.8	5.8
Ciprofolxacin	62	5.6	5.6
Ciprofloxacin Tablets	62	5.6	5.6
Ciprofloxacin Hydrochloride	81	5.4	5.5
Indomethacin	11	5.3	5.3
Daspone	8	5.3	5.3
Dapsone Gel, 5%	8	5.3	5.3
Clindamycin Phosphate	27	5.2	5.2
Ganciclovir	8	5.0	5.0
Levetiracetam	101	5.0	5.0
Ganciclovir Sodium	8	4.9	4.9
Dapsone	8	4.8	4.8
Cefazolin Sodium	9	4.8	4.8
Cefepime Hydrochloride	12	4.8	4.8
Oxcarbazepine	24	4.8	4.8
Emtricitabine And Tenofovir Disoproxil Fumarate	33	4.7	4.7
Olanzapine Pamoate	29	4.6	4.6
Diclofenac Sodium 1%	25	4.5	4.5
Diclofenac Sodium Topical	25	4.5	4.5
Diclofenac Sodium Topical Gel, 1%	25	4.5	4.5
Losartan Potassium And Hydrochlorothiazide	8	4.4	4.4
Rifampin	10	4.4	4.4
Levetiracetam In Sodium Chloride	52	4.4	4.4
Levetiracetam Oral	52	4.4	4.4
Levetiracetam Injection	52	4.4	4.4
Lithium	16	4.1	4.1
Lithium Bromatum	16	4.1	4.1
Quinapril Hydrochloride	5	4.1	4.1
Ritonavir 100 Mg	9	3.9	3.9
Tenofovir Disoproxil Fumarate Tablets	5	3.7	3.7
Clobazam	14	3.7	3.7
Linezolid	17	3.7	3.7
Cefepime	8	3.6	3.6
Tenofovir Disoproxil Fumarate	18	3.5	3.5
Levocetirizine Dihydrochloride	13	3.5	3.5
Rocuronium Bromide	6	3.3	3.3
Diclofenac Potassium, Film Coated	3	2.3	2.3
Diclofenac Potassium Tablets	3	2.3	2.3
Gefitinib	3	2.1	2.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.