Reaction

Hepatitis Toxic reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,591 reports · 80 co-occurring drugs

As of the last recalculation, Hepatitis Toxic appears in 2,591 FAERS reports alongside 80 co-occurring drug terms. The strongest observed disproportionality signal is PYRAZINAMIDE (PRR 67.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Pyrazinamide	77	67.8	68.4
Isoniazid	86	44.1	44.3
Rifampicin	39	31.4	31.5
Terbinafine Hydrochloride	14	12.7	12.7
Linezolid	46	12.6	12.6
Zidovudine	19	11.5	11.5
Ceftriaxone	44	10.9	11.0
Moxifloxacin	19	10.9	10.9
Abacavir Sulfate	13	10.8	10.8
Ursosiol	24	10.0	10.0
Rifampin	18	10.0	10.0
Nevirapine	11	9.8	9.8
Ceftriaxone Sodium	46	9.8	9.8
Acetylcysteine	11	9.4	9.4
Efavirenz	13	9.4	9.4
Ritonavir 100 Mg	17	9.2	9.2
Nebivolol	18	9.1	9.1
Ursodiol	24	8.9	8.9
Dronedarone	11	8.7	8.7
Cefuroxime	12	8.5	8.5
Tenofovir Disoproxil Fumarate Tablets	9	8.4	8.4
Cetirizine Hcl	9	7.9	7.9
Lamivudine	29	7.6	7.6
Moxifloxacin Hydrochloride	19	7.6	7.6
Cladribine	9	7.5	7.6
Posaconazole Delayed-Release	10	7.3	7.3
Lamivudine Oral	22	7.0	7.0
Fondaparinux Sodium	7	7.0	7.0
Darunavir	13	6.9	6.9
Dalteparin Sodium	9	6.9	6.9
Ado-Trastuzumab Emtansine	7	6.7	6.7
Daspone	8	6.6	6.6
Dapsone Gel, 5%	8	6.6	6.6
Posaconazole	13	6.5	6.5
Pemetrexed Disodium	30	6.4	6.4
Raltegravir	13	6.4	6.4
Voriconazole Injection	17	6.3	6.3
Chlorthalidone	9	6.2	6.2
Levofloxacin	46	6.2	6.2
Levofloxacin In 5% Dextrose	46	6.2	6.2
Atazanavir	11	6.2	6.2
Voriconazole	23	6.1	6.1
Dapsone	8	6.0	6.0
Pemetrexed	16	6.0	6.0
Meropenem	22	5.5	5.5
Rocuronium Bromide	8	5.5	5.5
Clarithromycin	23	5.4	5.4
Ribociclib	21	5.4	5.4
Propofol	24	5.3	5.3
Ritonavir	19	5.3	5.3
Axitinib	12	5.0	5.0
Pembrolizumab	63	4.9	4.9
Zonisamide	9	4.9	4.9
Obinutuzumab	10	4.9	4.9
Regorafenib	7	4.9	4.9
Brentuximab Vedotin	6	4.7	4.7
Interferon Beta-1B	11	4.6	4.6
Imatinib	10	4.6	4.6
Dolutegravir Sodium	5	4.5	4.5
Gefitinib	5	4.5	4.5
Bendamustine Hcl	8	4.2	4.2
Pegaspargase	6	3.9	3.9
Sevoflurane	4	3.9	3.9
Crizotinib	6	3.8	3.8
Abemaciclib	9	3.6	3.6
Vemurafenib	5	3.3	3.3
Tolvaptan	6	3.3	3.3
Polatuzumab Vedotin	4	3.3	3.3
Pertuzumab	11	3.3	3.3
Tenofovir Disoproxil Fumarate	13	3.2	3.2
Blinatumomab	4	3.1	3.1
Sunitinib Malate	15	3.1	3.1
Bosentan	18	2.9	2.9
Emtricitabine And Tenofovir Disoproxil Fumarate	16	2.8	2.8
Vismodegib	3	2.7	2.7
Pazopanib Hydrochloride	9	2.7	2.7
Dabrafenib	7	2.7	2.7
Remdesivir	4	2.4	2.4
Atezolizumab	11	2.3	2.3
Alirocumab	5	1.6	1.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.