Reaction

Appendicectomy reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,509 reports · 90 co-occurring drugs

As of the last recalculation, Appendicectomy appears in 3,509 FAERS reports alongside 90 co-occurring drug terms. The strongest observed disproportionality signal is ALENDRONATE SODIUM (PRR 23.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Alendronate Sodium	361	23.5	23.6
Etonogestrel And Ethinyl Estradiol	65	17.7	17.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	21	14.5	14.6
Risankizumab-Rzaa	165	12.5	12.5
Upadacitinib	112	8.4	8.4
Vedolizumab	114	8.1	8.1
Risedronate Sodium	35	6.7	6.7
Armodafinil	23	6.5	6.5
Hyoscyamine Sulfate	10	6.5	6.5
Ascorbic Acid	25	6.4	6.4
Dornase Alfa	20	6.1	6.1
Sodium Oxybate	66	6.0	6.0
Pancrelipase	38	5.9	5.9
Butalbital, Acetaminophen, And Caffeine	10	5.6	5.6
Polatuzumab Vedotin	9	5.5	5.5
Azathioprine	77	5.3	5.3
Sitagliptin And Metformin Hydrochloride	19	5.2	5.3
Amlodipine Besylate And Benazepril Hydrochloride	8	5.1	5.2
Infliximab-Dyyb	25	5.1	5.1
Sitagliptin	60	5.0	5.0
Cladribine	8	4.9	4.9
Vitamin E	26	4.9	4.9
Buspirone Hydrochloride	9	4.8	4.9
Carisoprodol	15	4.7	4.7
Rizatriptan Benzoate	8	4.7	4.7
Dicyclomine Hydrochloride	11	4.6	4.6
Mesalamine	43	4.6	4.6
Infliximab	159	4.5	4.5
Mercaptopurine	13	4.5	4.5
Naltrexone Hydrochloride And Bupropion Hydrochloride	6	4.2	4.2
Lumacaftor And Ivacaftor	6	4.2	4.2
Liothyronine Sodium	6	4.1	4.1
Modafinil	22	4.1	4.1
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	24	4.1	4.1
Finasteride	40	4.0	4.0
Cabotegravir	5	3.7	3.7
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	25	3.6	3.6
Interferon Beta-1A	113	3.6	3.6
Adalimumab	386	3.5	3.5
Valsartan And Hydrochlorothiazide	8	3.5	3.5
Oxycodone And Acetaminophen Tablets	7	3.5	3.5
Tobramycin Solution	7	3.5	3.5
Amantadine	9	3.5	3.5
Orlistat	15	3.4	3.4
Tobramycin Sulfate	7	3.4	3.4
Agalsidase Beta	5	3.2	3.2
Epoprostenol	7	3.2	3.2
Drospirenone And Ethinyl Estradiol	23	3.1	3.1
Bendamustine Hcl	8	3.1	3.1
Lisinopril And Hydrochlorothiazide Tablets	4	3.0	3.0
Vortioxetine	8	2.8	2.8
Bimekizumab	10	2.8	2.8
Peginterferon Beta-1A	6	2.7	2.7
Bosentan	23	2.7	2.7
Niraparib	10	2.7	2.7
Ustekinumab	45	2.6	2.6
Ixekizumab	16	2.6	2.6
Selexipag	11	2.5	2.5
Ibrutinib	34	2.5	2.5
Certolizumab Pegol	48	2.4	2.4
Macitentan	28	2.4	2.4
Elexacaftor, Tezacaftor, And Ivacaftor	5	2.4	2.4
Clozapine	49	2.3	2.3
Naltrexone	12	2.3	2.3
Isotretinoin	19	2.3	2.3
Fluticasone Propionate And Salmeterol	16	2.3	2.3
Oral Semaglutide	28	2.3	2.3
Leuprolide Acetate	29	2.2	2.2
Pegvaliase-Pqpz	3	2.2	2.2
Medroxyprogesterone Acetate	17	2.0	2.0
Golimumab	29	2.0	2.0
Etonogestrel	16	2.0	2.0
Brivaracetam	3	2.0	2.0
Natalizumab	60	2.0	2.0
Buprenorphine Hydrochloride, Naloxone Hydrochloride	8	2.0	2.0
Exenatide	16	1.8	1.8
Hydrocodone Bitartrate And Acetaminophen	17	1.8	1.8
Conjugated Estrogens And Medroxyprogesterone Acetate	7	1.8	1.8
Dimethyl Fumarate	36	1.7	1.7
Peginterferon Alfa-2A	15	1.6	1.6
Voxelotor	6	1.6	1.6
Ambrisentan	33	1.6	1.6
Fremanezumab-Vfrm	3	1.6	1.6
Guselkumab	9	1.5	1.5
Glatiramer Acetate	15	1.5	1.5
Droxidopa	4	1.1	1.1
Levonorgestrel	36	1.1	1.1
Relugolix	4	1.0	1.0
Copper	7	1.0	1.0
Dupilumab	77	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.