Reaction

Depression Suicidal reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,416 reports · 82 co-occurring drugs

As of the last recalculation, Depression Suicidal appears in 3,416 FAERS reports alongside 82 co-occurring drug terms. The strongest observed disproportionality signal is ATAZANAVIR (PRR 70.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Atazanavir	158	70.2	71.0
Ritonavir 100 Mg	138	58.6	59.2
Lopinavir And Ritonavir	117	54.4	54.9
Metoclopramide	364	45.1	45.4
Raltegravir	111	42.3	42.6
Ritonavir	155	33.8	34.0
Metoclopramide Hydrochloride	369	32.5	32.7
Lamivudine Oral	125	31.2	31.4
Lamivudine	126	25.8	25.9
Quetiapine Fumarate	106	22.6	22.6
Valproic Acid	111	22.1	22.2
Tenofovir Disoproxil Fumarate Tablets	29	20.6	20.7
Efavirenz	36	19.9	19.9
Bupropion	116	16.4	16.4
Tenofovir Disoproxil Fumarate	85	16.0	16.1
Valproate Sodium	49	14.6	14.7
Citalopram Hydrobromide	225	13.6	13.6
Finasteride	122	12.7	12.8
Citalopram	239	11.4	11.4
Sertraline	195	10.7	10.7
Clonazepam	229	9.3	9.3
Interferon Beta-1B	27	8.6	8.7
Quetiapine	247	8.3	8.4
Risperidone	169	8.1	8.1
Bupropion Hydrochloride	121	7.7	7.7
Montelukast	100	7.4	7.5
Sertraline Hydrochloride	121	6.4	6.4
Terbinafine Hydrochloride	9	6.2	6.2
Dutasteride	8	6.0	6.0
Fluoxetine	64	5.9	5.9
Theophylline	11	5.8	5.9
Venlafaxine	66	5.7	5.7
Drospirenone And Ethinyl Estradiol	40	5.6	5.6
Fexofenadine	15	5.6	5.6
Theophylline Anhydrous	11	5.4	5.4
Fexofenadine Hcl	8	5.3	5.3
Venlafaxine Hydrochloride	109	5.2	5.2
Fluoxetine Hydrochloride	102	5.0	5.0
Tranexamic Acid	7	4.8	4.8
Atomoxetine Hydrochloride	18	4.6	4.6
Diroximel Fumarate	9	4.6	4.6
Duloxetine	52	4.6	4.6
Canakinumab	8	4.5	4.5
Nicotine Polacrilex Mini	11	4.5	4.5
Nicotine Polarilex	11	4.5	4.5
Tizanidine Hydrochloride	13	4.4	4.4
Trazodone Hydrochloride	11	4.3	4.3
Progesterone	16	4.3	4.3
Levonorgestrel	137	4.3	4.3
Cetiirizine	29	4.2	4.2
Varenicline Tartrate	53	4.1	4.1
Lamotirigine	45	3.9	3.9
Lamotrigine Extended-Release	45	3.9	3.9
Lamotrigine Chewable Dispersible	45	3.9	3.9
Modafinil	20	3.8	3.8
Naltrexone Hydrochloride And Bupropion Hydrochloride	5	3.6	3.6
Isotretinoin	28	3.5	3.5
Brivaracetam	5	3.4	3.4
Sumatriptan Succinate	14	3.4	3.4
Cariprazine	5	3.3	3.3
Cenobamate	4	2.9	2.9
Natalizumab	82	2.8	2.8
Oral Semaglutide	33	2.8	2.8
Dimethyl Fumarate	55	2.8	2.8
Baricitinib	4	2.5	2.5
Vortioxetine	7	2.5	2.5
Desvenlafaxine Succinate	11	2.5	2.5
Apremilast	57	2.4	2.4
Esketamine Hydrochloride	7	2.4	2.4
Tirzepatide	58	2.2	2.2
Medroxyprogesterone Acetate	17	2.1	2.1
Etonogestrel	16	2.0	2.0
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	3	2.0	2.0
Peginterferon Beta-1A	4	1.9	1.9
Ethyl Alcohol	8	1.8	1.8
Olaparib	5	1.5	1.5
Valbenazine	6	1.5	1.5
Bimekizumab	5	1.4	1.4
Orlistat	6	1.4	1.4
Galcanezumab-Gnlm	6	1.2	1.2
Paliperidone Palmitate	6	1.1	1.1
Erenumab-Aooe	10	1.1	1.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.