Reaction

Muscle Fatigue reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,172 reports · 112 co-occurring drugs

As of the last recalculation, Muscle Fatigue appears in 4,172 FAERS reports alongside 112 co-occurring drug terms. The strongest observed disproportionality signal is RAVULIZUMAB (PRR 17.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ravulizumab	48	17.9	18.0
Losartan Potassium And Hydrochlorothiazide	30	13.0	13.0
Inclisiran	13	8.1	8.1
Risedronate Sodium	47	7.6	7.6
Dalfampridine	105	7.5	7.5
Alirocumab	33	6.6	6.6
Niacin	15	6.5	6.5
Relugolix	29	6.2	6.2
Ezetimibe	86	5.8	5.8
Asfotase Alfa	11	5.5	5.5
Ofatumumab	34	5.1	5.1
Vismodegib	9	5.1	5.1
Diroximel Fumarate	12	5.0	5.0
Ciprofolxacin	65	4.6	4.6
Ciprofloxacin Tablets	65	4.6	4.6
Selexipag	23	4.5	4.5
Octreotide Acetate	27	4.4	4.4
Ciprofloxacin Hydrochloride	84	4.4	4.4
Ketoconazole	15	4.3	4.3
Itraconazole	10	4.3	4.3
Ezetimibe And Simvastatin	13	4.3	4.3
Ciprofloxacin	76	4.2	4.2
Sulfur	7	4.1	4.2
Testosterone	19	4.1	4.1
Niraparib	18	4.1	4.1
Rasagiline Mesylate	9	4.0	4.0
Diphenoxylate Hydrochloride And Atropine Sulfate	11	4.0	4.0
Elexacaftor, Tezacaftor, And Ivacaftor	10	4.0	4.0
Indapamide	14	3.9	3.9
Sorafenib	16	3.9	3.9
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	23	3.8	3.8
Thyroid, Porcine	8	3.8	3.8
Abaloparatide	22	3.7	3.7
Atorvastatin Calcium	175	3.6	3.6
Multivitamin	36	3.6	3.6
Rosuvastatin	143	3.6	3.6
Ocrelizumab	44	3.6	3.6
Cetiirizine	30	3.6	3.6
Fenofibrate	25	3.5	3.5
Sulfasalazine	54	3.5	3.5
Regorafenib	8	3.4	3.4
Peginterferon Beta-1A	9	3.4	3.4
Oxybutynin Chloride	6	3.4	3.4
Modafinil	22	3.4	3.4
Baclofen	58	3.4	3.4
Rucaparib	6	3.4	3.4
Ketoconazole Foam	10	3.4	3.4
Ketoconazole Cream, 2%	10	3.4	3.4
Pravastatin Sodium	13	3.3	3.3
Amantadine	10	3.2	3.2
Tizanidine	15	3.1	3.1
Dimethyl Fumarate	76	3.1	3.1
Naltrexone	19	3.1	3.1
Atorvastatin Calcium, Film Coated	42	3.0	3.0
Zoledronic Acid	24	3.0	3.0
Fingolimod Hcl	51	3.0	3.0
Rifampicin	6	3.0	3.0
Pitavastatin Calcium	6	2.9	2.9
Voclosporin	5	2.9	2.9
Armodafinil	12	2.8	2.8
Ibuprofen Tablets, Coated	24	2.8	2.8
Botulinum Toxin Type A	7	2.8	2.8
Ibuprofen Sodium	24	2.8	2.8
Teriparatide	62	2.8	2.8
Eculizumab	29	2.7	2.7
Interferon Beta-1B	10	2.6	2.6
Drospirenone And Ethinyl Estradiol	23	2.6	2.6
Dapagliflozin	16	2.5	2.5
Interferon Beta-1A	97	2.5	2.5
Leuprolide Acetate	38	2.5	2.5
Brexpiprazole	8	2.4	2.4
Suvorexant	6	2.3	2.3
Medroxyprogesterone Acetate	23	2.3	2.3
Riociguat	15	2.3	2.3
Natalizumab	82	2.3	2.3
Siponimod	4	2.2	2.2
Fremanezumab-Vfrm	5	2.2	2.2
Onabotulinumtoxina	33	2.1	2.1
Pemetrexed Disodium	16	2.1	2.1
Evolocumab	67	2.1	2.1
Avapritinib	5	2.1	2.1
Ticagrelor	13	2.0	2.0
Enzalutamide	23	2.0	2.0
Glatiramer Acetate	23	1.9	1.9
Cabotegravir	3	1.9	1.9
Tofacitinib	67	1.8	1.8
Pegvaliase-Pqpz	3	1.8	1.8
Ozanimod Hydrochloride	3	1.8	1.8
Ruxolitinib	25	1.7	1.7
Selinexor	3	1.7	1.7
Asenapine Maleate	3	1.7	1.7
Pirfenidone	14	1.7	1.7
Lenvatinib	11	1.7	1.7
Lurasidone Hydrochloride	7	1.7	1.7
Teriflunomide	15	1.7	1.7
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	6	1.7	1.7
Rimegepant Sulfate	4	1.6	1.6
Dornase Alfa	6	1.5	1.5
Abiraterone	4	1.5	1.5
Emtricitabine And Tenofovir Alafenamide	3	1.3	1.3
Nemolizumab-Ilto	3	1.2	1.2
Velpatasvir And Sofosbuvir	3	1.2	1.2
Abiraterone Acetate	9	1.1	1.1
Paliperidone Palmitate	7	1.1	1.1
Erenumab-Aooe	11	1.0	1.0
Nirmatrelvir And Ritonavir	9	0.8	0.8
Valbenazine	4	0.8	0.8
Etonogestrel	7	0.7	0.7
Pomalidomide	15	0.7	0.7
Apremilast	21	0.7	0.7
Tirzepatide	22	0.7	0.7
Cinacalcet Hydrochloride	6	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.