Reaction

Which drugs are most reported with Loss of libido?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 8,864 reports · 134 co-occurring drugs

As of the last recalculation, Loss Of Libido appears in 8,864 FAERS reports alongside 134 co-occurring drug terms. The strongest observed disproportionality signal is FINASTERIDE (PRR 80.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Finasteride	1,676	80.2	82.5
Levonorgestrel	1,427	19.6	19.8
Relugolix	121	12.2	12.3
Escitslopram	224	9.3	9.3
Paroxetine Hydrochloride Hemihydrate	126	9.0	9.0
Paroxetine	126	8.8	8.8
Sertraline	417	8.7	8.7
Escitalopram Oxalate	250	8.3	8.3
Paroxetine Hydrochloride	272	7.2	7.2
Citalopram Hydrobromide	299	6.7	6.8
Paliperidone	65	6.6	6.6
Paliperidone Palmitate	89	6.5	6.6
Fluoxetine	181	6.5	6.5
Dutasteride	22	6.4	6.4
Testosterone	62	6.3	6.3
Minoxidil Foam 5% (Womens)	83	6.0	6.0
Citalopram	326	5.8	5.8
Escitalopram	324	5.6	5.6
Fluoxetine Hydrochloride	285	5.4	5.4
Leuprolide Acetate	167	5.1	5.1
Venlafaxine	154	5.1	5.1
Venlafaxine Hydrochloride	281	5.1	5.1
Aripiprazole Oral	88	5.0	5.0
Aripiprazole Orally Disintegrating	88	5.0	5.0
Etonogestrel And Ethinyl Estradiol	46	4.9	4.9
Testosterone Cypionate	18	4.7	4.7
Minoxidil	86	4.5	4.5
Lutetium Lu 177 Vipivotide Tetraxetan	25	4.5	4.5
Bicalutamide	28	4.3	4.3
Isotretinoin	88	4.2	4.2
Goserelin	23	4.0	4.0
Primidone	17	3.9	3.9
Etonogestrel	73	3.6	3.6
Medroxyprogesterone Acetate	75	3.6	3.6
Sertraline Hydrochloride	173	3.5	3.5
Vortioxetine	24	3.3	3.3
Vilazodone Hydrochloride	13	3.3	3.3
Nicotine Polacrilex Mini	21	3.3	3.3
Nicotine Polarilex	21	3.3	3.3
Aripiprazole	165	3.2	3.2
Desvenlafaxine Succinate	36	3.1	3.1
Bupropion	58	3.1	3.1
Temazepam	48	3.0	3.0
Mirtazapine	116	3.0	3.0
Quetiapine Fumarate	37	3.0	3.0
Bupropion Hydrochloride	122	2.9	2.9
Tamsulosin Hydrochloride	24	2.8	2.8
Quinine	10	2.7	2.7
Brexpiprazole	19	2.7	2.7
Drospirenone And Ethinyl Estradiol	49	2.6	2.6
Duloxetine Hydrochloride	198	2.5	2.5
Indapamide	19	2.5	2.5
Zinc	26	2.5	2.5
Zinc Chloride	26	2.5	2.5
Risperidone	136	2.4	2.4
Trazodone Hydrochloride	16	2.4	2.4
Apalutamide	12	2.4	2.4
Lurasidone Hydrochloride	21	2.4	2.4
Zinc Gluconate	26	2.3	2.3
Duloxetine	67	2.3	2.3
Quetiapine	180	2.2	2.2
Hydrocodone Bitartrate And Acetaminophen	52	2.2	2.2
Atomoxetine Hydrochloride	22	2.2	2.2
Asenapine Maleate	8	2.2	2.2
Buprenorphine Hydrochloride, Naloxone Hydrochloride	22	2.1	2.1
Desoximetasone	17	2.1	2.1
Lacosamide	33	2.1	2.1
Lithium Carbonate	14	1.9	1.9
Diazepam Oral Solution (Concentrate)	73	1.9	1.9
Diazepam Oral	73	1.9	1.9
Tadalafil	79	1.9	1.9
Terbinafine Hydrochloride	7	1.9	1.9
Multivitamin	39	1.8	1.8
Docetaxel Anhydrous	51	1.8	1.8
Docetaxel	51	1.8	1.8
Thyroid, Porcine	8	1.8	1.8
Enzalutamide	44	1.8	1.8
Methylphenidate Hydrochloride	44	1.7	1.7
Diazepam	89	1.7	1.7
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	13	1.7	1.7
Propranolol Hydrochloride	51	1.7	1.7
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	25	1.7	1.7
Liothyronine Sodium	6	1.6	1.6
Anastrozole	25	1.6	1.6
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	28	1.6	1.6
Sildenafil Powder,	24	1.6	1.6
Lithium	17	1.6	1.6
Lithium Bromatum	17	1.6	1.6
Divalproex Sodium	31	1.6	1.6
Fexofenadine	11	1.6	1.6
Sildenafil Citrate	84	1.6	1.6
Abiraterone	9	1.6	1.6
Acetaminophen And Codeine	8	1.5	1.5
Progesterone	15	1.5	1.5
Cariprazine	6	1.5	1.5
Doxazosin	18	1.5	1.5
Estradiol Gel 0.1%	29	1.5	1.5
Estradiol Transdermal	29	1.5	1.5
Guanfacine	5	1.5	1.5
Nicotine Polacrilex	24	1.5	1.5
Sildenafil	36	1.5	1.5
Levetiracetam In Sodium Chloride	48	1.5	1.5
Levetiracetam Oral	48	1.5	1.5
Levetiracetam Injection	48	1.5	1.5
Emtricitabine And Tenofovir Alafenamide	7	1.5	1.5
Amphetamine	5	1.4	1.4
Copper	26	1.4	1.4
Valproic Acid	19	1.4	1.4
Atazanavir	8	1.3	1.3
Dolutegravir Sodium	5	1.3	1.3
Naltrexone	17	1.3	1.3
Raltegravir	9	1.3	1.3
Levetiracetam	71	1.3	1.3
Clozapine	66	1.2	1.2
Nicotine	21	1.2	1.2
Varenicline Tartrate	41	1.2	1.2
Emtricitabine And Tenofovir Disoproxil Fumarate	23	1.2	1.2
Inclisiran	4	1.2	1.2
Methylphenidate	14	1.1	1.1
Cenobamate	4	1.1	1.1
Oxycodone Hydrochloride	101	1.1	1.1
Methadone Hydrochloride	5	1.1	1.1
Lisdexamfetamine Dimesylate	15	1.1	1.1
Fremanezumab-Vfrm	5	1.0	1.0
Hydromorphone Hydrochloride	39	1.0	1.0
Abiraterone Acetate	17	1.0	1.0
Naltrexone Hydrochloride And Bupropion Hydrochloride	3	0.8	0.8
Conjugated Estrogens And Medroxyprogesterone Acetate	8	0.8	0.8
Buprenorphine	31	0.8	0.8
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	3	0.8	0.8
Ledipasvir And Sofosbuvir	5	0.6	0.6
Valbenazine	6	0.6	0.6
Hydrocodone Bitartrate	10	0.5	0.5
Tapentadol Hydrochloride	6	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.