Reaction

Lumbar Vertebral Fracture reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,482 reports · 141 co-occurring drugs

As of the last recalculation, Lumbar Vertebral Fracture appears in 4,482 FAERS reports alongside 141 co-occurring drug terms. The strongest observed disproportionality signal is ROMOSOZUMAB-AQQG (PRR 28.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Romosozumab-Aqqg	82	28.6	28.7
Denosumab	639	16.9	17.0
Raloxifene Hydrochloride	40	12.8	12.9
Alendronate Sodium	258	12.5	12.6
Alendronate Sodium Tablet	47	11.9	11.9
Teriparatide	270	11.8	11.8
Risedronate Sodium	68	10.3	10.3
Calcium	244	8.0	8.0
Zoledronic Acid	65	7.6	7.6
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	28	7.2	7.2
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	13	6.7	6.7
Teduglutide	18	6.2	6.2
Magnesium Sulfate In Water For	17	6.2	6.2
Dimenhydrinate	14	6.1	6.1
Magnesium Sulfate Heptahydrate	17	6.1	6.1
Magnesium Sulfate	17	6.1	6.1
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	13	6.0	6.0
Emtricitabine And Tenofovir Alafenamide	14	5.7	5.8
Prochlorperazine Maleate	11	5.6	5.6
Candesartan	42	5.5	5.5
Oxazepam	25	5.4	5.4
Fosaprepitant Dimeglumine	16	5.4	5.4
Dutasteride	9	5.1	5.2
Goserelin	14	4.9	4.9
Magnesium Hydroxide	14	4.8	4.8
Antacid	49	4.8	4.8
Baricitinib	10	4.8	4.8
Human Immunoglobulin G	21	4.7	4.7
Emtricitabine And Tenofovir Disoproxil Fumarate	46	4.7	4.7
Calcitriol Capsules 0.25 Mcg	20	4.7	4.7
Calcitriol Capsules 0.5 Mcg	20	4.7	4.7
Calcitriol	20	4.6	4.6
Calcium Carbonate	65	4.5	4.5
Ixazomib	28	4.5	4.5
Magnesium	79	4.5	4.5
Methocarbamol	22	4.5	4.5
Diltiazem Hydrochloride Extended-Release Tablets	11	4.5	4.5
Methocarbamol Tablets	16	4.4	4.5
Tenofovir Disoproxil Fumarate	31	4.4	4.4
Magnesium Oxide	39	4.4	4.4
Polyethylene Glycol	10	4.3	4.3
Oxycodone And Acetaminophen Tablets	11	4.3	4.3
Aprepitant	17	4.3	4.3
Rasagiline Mesylate	10	4.2	4.2
Tolterodine Tartrate	8	4.1	4.1
Lopinavir And Ritonavir	12	4.1	4.1
Doxepin Hydrochloride	11	4.1	4.1
Acetylcysteine	8	3.9	4.0
Exemestane	18	3.9	3.9
Torsemide	27	3.8	3.8
Letrozole Tablets	39	3.8	3.8
Letrozole	49	3.7	3.7
Doxepin	8	3.7	3.7
Terazosin Hydrochloride	7	3.7	3.7
Ergocalciferol	289	3.7	3.7
Febuxostat Tablets 40 Mg	8	3.7	3.7
Febuxostat Tablets 80 Mg	8	3.7	3.7
Cyclobenzaprine	39	3.7	3.7
Ropinirole	12	3.6	3.6
Duloxetine	53	3.6	3.6
Ribociclib	24	3.5	3.5
Fexofenadine Hcl	7	3.5	3.5
Daratumumab	30	3.5	3.5
Buprenorphine Hydrochloride, Naloxone Hydrochloride	18	3.5	3.5
Mupirocin	10	3.4	3.5
Sennosides	22	3.4	3.4
Mupirocin Calcium	10	3.4	3.4
Meloxicam	42	3.4	3.4
Abacavir Sulfate	7	3.3	3.3
Doxazosin	20	3.3	3.3
Abaloparatide	21	3.3	3.3
Leflunomide	71	3.2	3.2
Granisetron Hydrochloride	7	3.1	3.1
Upadacitinib	53	3.0	3.0
Pemetrexed	14	3.0	3.0
Diclofenac Sodium 1%	23	3.0	3.0
Diclofenac Sodium Topical	23	3.0	3.0
Diclofenac Sodium Topical Gel, 1%	23	3.0	3.0
Doxazosin Mesylate	23	3.0	3.0
Mepolizumab	31	2.9	2.9
Bortezomib	54	2.8	2.8
Eltrombopag Olamine	14	2.8	2.8
Oxycodone And Acetaminophen	14	2.8	2.8
Thalidomide	22	2.8	2.8
Asfotase Alfa	6	2.8	2.8
Bicalutamide	9	2.7	2.7
Ibrutinib	47	2.7	2.7
Donepezil Hydrochloride	21	2.7	2.7
Fentanyl Citrate	10	2.6	2.6
Fluticasone Furoate And Vilanterol Trifenatate	20	2.6	2.6
Dexamethasone 1.5 Mg	158	2.6	2.6
Dexamethasone	158	2.5	2.5
Febuxostat	9	2.5	2.5
Acyclovir	59	2.4	2.4
Entecavir	6	2.4	2.4
Oxycodone Hydrochloride And Acetaminophen	49	2.3	2.3
Timolol	6	2.3	2.3
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	4	2.3	2.3
Oxycodone	90	2.3	2.3
Rotigotine	7	2.2	2.3
Pembrolizumab	50	2.2	2.2
Granisetron	5	2.2	2.2
Pemetrexed Disodium	18	2.2	2.2
Mirabegron	18	2.2	2.2
Calcium, Magnesium, Potassium, And Sodium Oxybates	4	2.2	2.2
Travoprost	4	2.1	2.1
Fesoterodine Fumarate	5	2.1	2.1
Benralizumab	9	2.1	2.1
Dapagliflozin	14	2.1	2.1
Risankizumab-Rzaa	33	1.9	1.9
Azacitidine For	7	1.8	1.8
Lenalidomide	159	1.8	1.8
Vibegron	3	1.7	1.7
Ocrelizumab	23	1.7	1.7
Azacitidine	11	1.7	1.7
Leuprolide Acetate	28	1.7	1.7
Golimumab	30	1.6	1.6
Selinexor	3	1.6	1.6
Dabigatran Etexilate Mesylate	25	1.6	1.6
Tolvaptan	5	1.6	1.6
Nivolumab	33	1.6	1.6
Apalutamide	4	1.6	1.6
Oxycodone Hydrochloride	73	1.6	1.6
Dabigatran Etexilate	26	1.6	1.6
Acalabrutinib	4	1.5	1.5
Cortisone Acetate	4	1.5	1.5
Polatuzumab Vedotin	3	1.4	1.4
Paliperidone	7	1.4	1.4
Ravulizumab	4	1.4	1.4
Palbociclib	28	1.4	1.4
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	12	1.3	1.3
Pimavanserin Tartrate	16	1.3	1.3
Enzalutamide	17	1.3	1.3
Budesonide, Glycopyrrolate, And Formoterol Fumarate	3	1.3	1.3
Paricalcitol	4	1.3	1.3
Droxidopa	6	1.3	1.3
Sarilumab	7	1.2	1.2
Pomalidomide	27	1.2	1.2
Tafamidis	3	1.2	1.2
Durvalumab	5	1.1	1.1
Valbenazine	3	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.