Reaction

Tongue Discomfort reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,154 reports · 114 co-occurring drugs

As of the last recalculation, Tongue Discomfort appears in 4,154 FAERS reports alongside 114 co-occurring drug terms. The strongest observed disproportionality signal is CABOZANTINIB (PRR 25.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Cabozantinib	227	25.0	25.1
Sunitinib Malate	103	13.4	13.5
Nicotine Polacrilex	81	10.8	10.8
Chlorhexidine Gluconate	19	10.5	10.5
Asenapine Maleate	17	9.9	9.9
Nicotine	71	8.9	8.9
Lenvatinib	57	8.8	8.8
Axitinib	34	8.8	8.8
Efavirenz	18	8.1	8.1
Alpelisib	14	8.1	8.1
Buprenorphine Hydrochloride, Naloxone Hydrochloride	37	7.7	7.8
Regorafenib	17	7.4	7.4
Umeclidinium	13	7.3	7.3
Fluticasone Furoate And Vilanterol Trifenatate	47	6.6	6.6
Niraparib	29	6.6	6.6
Terbinafine Hydrochloride	11	6.2	6.2
Losartan Potassium And Hydrochlorothiazide	13	5.6	5.6
Sorafenib	21	5.1	5.1
Ibuprofen Tablets, Coated	42	5.0	5.0
Naproxen Sodium Tablet	52	5.0	5.0
Ibuprofen Sodium	42	5.0	5.0
Loperamide Hydrochloride Oral	10	4.9	4.9
Budesonide, Glycopyrrolate, And Formoterol Fumarate	10	4.8	4.8
Drs. Clotrimazole	11	4.8	4.8
Family Wellness Clotrimazole	11	4.8	4.8
Clotrimazole Topical	11	4.8	4.8
Rimegepant Sulfate	12	4.8	4.8
Thyroid, Porcine	10	4.7	4.7
Nirmatrelvir And Ritonavir	50	4.7	4.7
Clotrimazole	11	4.5	4.5
Tiotropium Bromide Inhalation Spray	10	4.5	4.5
Loperamide Hydrochloride	39	4.4	4.4
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	36	4.4	4.4
Vitamin C	77	4.3	4.3
Loperamide Hydrochloride And Dimethicone	27	4.2	4.2
Oxycodone And Acetaminophen Tablets	10	4.2	4.2
Umeclidinium Bromide And Vilanterol Trifenatate	14	4.2	4.2
Cholestyramine	10	4.2	4.2
Zinc	20	4.1	4.1
Zinc Chloride	20	4.1	4.1
Anastrozole Tablets	17	4.0	4.0
Magnesium	64	3.9	3.9
Loperamide Hcl	10	3.9	3.9
Amikacin	13	3.8	3.8
Calcitriol Capsules 0.25 Mcg	15	3.8	3.8
Calcitriol Capsules 0.5 Mcg	15	3.8	3.8
Vibegron	6	3.8	3.8
Fluticasone Furoate	9	3.7	3.7
Calcitriol	15	3.7	3.7
Naproxen Sodium Tablet, Coated	10	3.7	3.7
Naproxen Sodium, Coated Tablets	10	3.7	3.7
Naproxen Sodium 220Mg	10	3.7	3.7
Ribociclib	23	3.7	3.7
Baricitinib	7	3.6	3.6
Azelastine	13	3.6	3.6
Tizanidine	17	3.6	3.6
Estradiol Gel 0.1%	32	3.6	3.6
Estradiol Transdermal	32	3.6	3.6
Letrozole Tablets	34	3.6	3.6
Budesonide And Formoterol Fumarate Dihydrate	66	3.4	3.4
Desoximetasone	13	3.4	3.4
Losartan Potassium	53	3.4	3.4
Tapentadol Hydrochloride	22	3.3	3.3
Ropinirole	10	3.3	3.3
Prochlorperazine Maleate	6	3.3	3.3
Lisdexamfetamine Dimesylate	21	3.2	3.2
Lanreotide Acetate	5	3.2	3.2
Everolimus	32	3.2	3.2
Fluticasone Propionate And Salmeterol	26	3.1	3.1
Lovastatin	16	3.1	3.1
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	31	3.1	3.1
Mirabegron	24	3.1	3.1
Lifitegrast	10	3.1	3.1
Losartan	100	2.9	2.9
Rucaparib	5	2.8	2.8
Testosterone Cypionate	5	2.8	2.8
Nintedanib	15	2.4	2.4
Nivolumab	46	2.4	2.4
Buprenorphine	43	2.3	2.3
Palbociclib	44	2.3	2.3
Linaclotide	12	2.3	2.3
Vismodegib	4	2.3	2.3
Mometasone Furoate And Formoterol Fumarate Dihydrate	7	2.3	2.3
Panitumumab	7	2.2	2.2
Sarilumab	11	2.1	2.1
Elexacaftor, Tezacaftor, And Ivacaftor	5	2.0	2.0
Teriflunomide	18	2.0	2.0
Inclisiran	3	1.9	1.9
Trifluridine And Tipiracil	4	1.9	1.9
Oral Semaglutide	27	1.8	1.8
Valbenazine	9	1.8	1.8
Diclofenac Potassium, Film Coated	3	1.8	1.8
Diclofenac Potassium Tablets	3	1.8	1.8
Pembrolizumab	37	1.8	1.8
Emtricitabine And Tenofovir Alafenamide	4	1.8	1.8
Abemaciclib	7	1.8	1.8
Fremanezumab-Vfrm	4	1.7	1.7
Treprostinil	43	1.7	1.7
Siponimod	3	1.7	1.7
Diroximel Fumarate	4	1.7	1.7
Bimekizumab	7	1.6	1.6
Botulinum Toxin Type A	4	1.6	1.6
Alirocumab	8	1.6	1.6
Fam-Trastuzumab Deruxtecan-Nxki	3	1.5	1.5
Romosozumab-Aqqg	4	1.5	1.5
Olaparib	6	1.4	1.4
Abaloparatide	6	1.0	1.0
Evolocumab	33	1.0	1.0
Pomalidomide	18	0.9	0.9
Galcanezumab-Gnlm	5	0.8	0.8
Erenumab-Aooe	8	0.7	0.7
Pimavanserin Tartrate	7	0.6	0.6
Tirzepatide	20	0.6	0.6
Dupilumab	55	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.